Motif ID: AGUGGUU

Z-value: 1.091


Mature miRNA associated with seed AGUGGUU:

NamemiRBase Accession
hsa-miR-140-5p MIMAT0000431



Activity profile for motif AGUGGUU.

activity profile for motif AGUGGUU


Sorted Z-values histogram for motif AGUGGUU

Sorted Z-values for motif AGUGGUU



Network of associatons between targets according to the STRING database.



First level regulatory network of AGUGGUU

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr2_-_217560247 5.818 NM_000599
 IGFBP5
insulin-like growth factor binding protein 5
chr5_-_172756505 4.403 NM_003714
 STC2
stanniocalcin 2
chr1_-_68299047 4.253 NM_018841
 GNG12
guanine nucleotide binding protein (G protein), gamma 12
chr6_+_168841829 4.051 NM_001166412
NM_022138
 SMOC2

SPARC related modular calcium binding 2

chr5_+_32710742 3.937 NM_001204376
 NPR3
natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C)
chr1_+_82266081 3.872 NM_012302
 LPHN2
latrophilin 2
chr5_+_38845962 3.832 NM_003999
 OSMR
oncostatin M receptor
chr1_+_159141376 3.776 NM_021189
NM_001127173
 CADM3

cell adhesion molecule 3

chr5_+_32711437 3.761 NM_000908
NM_001204375
 NPR3

natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C)

chr5_-_141704575 3.372 NM_001127496
NM_030964
 SPRY4

sprouty homolog 4 (Drosophila)

chr5_-_38595506 3.228 NM_002310
 LIFR
leukemia inhibitory factor receptor alpha
chr15_-_48937795 3.217 NM_000138
 FBN1
fibrillin 1
chr4_-_174451356 3.060 NM_021973
 HAND2
heart and neural crest derivatives expressed 2
chr10_-_7661613 2.948 NM_032817
 ITIH5
inter-alpha-trypsin inhibitor heavy chain family, member 5
chr7_-_42276617 2.905 NM_000168
 GLI3
GLI family zinc finger 3
chr5_-_38556682 2.889 NM_001127671
 LIFR
leukemia inhibitory factor receptor alpha
chr11_+_12695851 2.824 NM_021961
 TEAD1
TEA domain family member 1 (SV40 transcriptional enhancer factor)
chr4_+_55095263 2.807 NM_006206
 PDGFRA
platelet-derived growth factor receptor, alpha polypeptide
chr11_-_8932497 2.712 NM_005418
 ST5
suppression of tumorigenicity 5
chr1_-_79472360 2.594 NM_022159
 ELTD1
EGF, latrophilin and seven transmembrane domain containing 1

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 29 entries
Enrichment   P-value GO Accession GO Term
39.22 3.41e-02 GO:0001759 organ induction
12.36 3.12e-02 GO:0021537 telencephalon development
7.81 3.28e-04 GO:0022603 regulation of anatomical structure morphogenesis
6.90 4.10e-02 GO:0040007 growth
6.88 1.23e-02 GO:0035295 tube development
6.04 3.09e-02 GO:0001501 skeletal system development
4.60 9.50e-04 GO:2000026 regulation of multicellular organismal development
4.07 1.74e-03 GO:0050793 regulation of developmental process
4.02 4.61e-03 GO:0009888 tissue development
3.86 3.34e-03 GO:0042127 regulation of cell proliferation
3.27 4.53e-02 GO:0010646 regulation of cell communication
3.04 8.05e-04 GO:0007166 cell surface receptor linked signaling pathway
3.03 4.35e-04 GO:0048513 organ development
3.03 9.74e-03 GO:0007399 nervous system development
3.00 1.11e-02 GO:0009653 anatomical structure morphogenesis
2.89 1.37e-06 GO:0048731 system development
2.80 1.70e-03 GO:0030154 cell differentiation
2.73 2.72e-03 GO:0048869 cellular developmental process
2.67 7.51e-07 GO:0007275 multicellular organismal development
2.60 2.10e-05 GO:0048856 anatomical structure development

Gene overrepresentation in compartment category:

Showing 1 to 7 of 7 entries
Enrichment   P-value GO Accession GO Term
6.55 7.84e-04 GO:0005578 proteinaceous extracellular matrix
5.55 2.90e-03 GO:0031012 extracellular matrix
3.23 7.71e-03 GO:0044421 extracellular region part
2.58 1.76e-03 GO:0005576 extracellular region
2.52 1.52e-03 GO:0044459 plasma membrane part
1.86 1.04e-02 GO:0005886 plasma membrane
1.83 1.38e-02 GO:0071944 cell periphery

Gene overrepresentation in function category:

Showing 1 to 6 of 6 entries
Enrichment   P-value GO Accession GO Term
148.14 5.61e-03 GO:0004924 oncostatin-M receptor activity
4.80 9.49e-03 GO:0042803 protein homodimerization activity
3.96 8.62e-03 GO:0046983 protein dimerization activity
3.91 9.80e-03 GO:0005509 calcium ion binding
3.44 2.95e-02 GO:0042802 identical protein binding
1.64 4.39e-04 GO:0005515 protein binding