Motif ID: AIRE.p2

Z-value: 1.396


Transcription factors associated with AIRE.p2:

Gene SymbolEntrez IDGene Name
AIRE 326 autoimmune regulator

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
AIREhg19_v1_chr21_+_45705720_457057690.271.4e-01Click!


Activity profile for motif AIRE.p2.

activity profile for motif AIRE.p2


Sorted Z-values histogram for motif AIRE.p2

Sorted Z-values for motif AIRE.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of AIRE.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr19_-_14785626 9.636 NM_032571
EMR3
egf-like module containing, mucin-like, hormone receptor-like 3
chr1_+_84630575 8.771 NM_001242860
NM_001242861
PRKACB

protein kinase, cAMP-dependent, catalytic, beta

chr4_-_74847669 7.765 NM_002619
PF4
platelet factor 4
chr7_-_38313232 7.519 NM_001003799
NM_001003806
TARP

TRGV9
TCR gamma alternate reading frame protein

T cell receptor gamma variable 9
chr3_+_46395224 6.045 NM_001123041
NM_001123396
CCR2

chemokine (C-C motif) receptor 2

chr19_-_39826676 5.939 NM_004877
GMFG
glia maturation factor, gamma
chr19_-_8642337 5.735 MYO1F
myosin IF
chr15_+_58430394 5.502 NM_020980
AQP9
aquaporin 9
chr7_-_115608366 4.719 NM_001244583
TFEC
transcription factor EC
chr13_-_99910548 4.567 NM_001098200
NM_005292
GPR18

G protein-coupled receptor 18

chr19_+_52266640 4.001 NM_001462
FPR2
formyl peptide receptor 2
chr1_-_169680677 3.930 NM_000655
SELL
selectin L
chr3_-_194119994 3.830 NM_004488
GP5
glycoprotein V (platelet)
chr3_-_150920946 3.703 NM_013308
GPR171
G protein-coupled receptor 171
chr4_-_84035888 3.602 PLAC8
placenta-specific 8
chr4_+_15704752 3.574 BST1
bone marrow stromal cell antigen 1
chr17_-_72709010 3.553 NM_139018
CD300LF
CD300 molecule-like family member f
chr12_-_53600999 3.548 NM_000889
ITGB7
integrin, beta 7
chr14_-_106725232 3.273 ZCWPW2
IGHV3-23
IGKV3-20
IGK@
zinc finger, CW type with PWWP domain 2
immunoglobulin heavy variable 3-23
immunoglobulin kappa variable 3-20
immunoglobulin kappa locus
chr1_+_160709038 3.072 NM_021181
SLAMF7
SLAM family member 7
chr17_-_34207308 3.031 NM_002985
CCL5
chemokine (C-C motif) ligand 5
chr14_-_106714594 2.986


chr2_+_218989997 2.956 NM_001168298
CXCR2
chemokine (C-X-C motif) receptor 2
chr17_-_6983503 2.898 NM_006344
NM_182906
CLEC10A

C-type lectin domain family 10, member A

chr11_-_73693883 2.811 NM_003355
UCP2
uncoupling protein 2 (mitochondrial, proton carrier)
chr2_-_32490688 2.773 NM_001199139
NM_021209
NLRC4

NLR family, CARD domain containing 4

chr2_+_29038862 2.737 NM_001008779
SPDYA
speedy homolog A (Xenopus laevis)
chr6_-_159466019 2.704 NM_054114
NM_138810
NM_152133
TAGAP


T-cell activation RhoGTPase activating protein


chr6_-_32784727 2.669 NM_002120
HLA-DOB
major histocompatibility complex, class II, DO beta
chr4_-_84035908 2.641 NM_001130715
NM_016619
PLAC8

placenta-specific 8

chr1_+_161185084 2.637 NM_004106
FCER1G
Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide
chr19_+_1026271 2.628 NM_004368
NM_201277
CNN2

calponin 2

chr12_-_10282680 2.588 NM_022570
NM_197947
NM_197948
NM_197949
NM_197950
NM_197954
CLEC7A





C-type lectin domain family 7, member A





chr17_+_65936590 2.567 BPTF
bromodomain PHD finger transcription factor
chr1_+_181002560 2.538 NM_001194999
NM_001195000
NM_001195035
NM_001531
MR1



major histocompatibility complex, class I-related



chr1_+_161185061 2.515 FCER1G
Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide
chr19_+_50936159 2.505 NM_004533
MYBPC2
myosin binding protein C, fast type
chr2_-_87018802 2.422 NM_001768
NM_171827
CD8A

CD8a molecule

chr19_+_7599037 2.419 NM_006702
NM_001166112
PNPLA6

patatin-like phospholipase domain containing 6

chr2_-_85637486 2.415 NM_001747
CAPG
capping protein (actin filament), gelsolin-like
chr1_-_89664510 2.394 NM_052941
GBP4
guanylate binding protein 4
chr12_-_10151689 2.387 NM_001099431
NM_016509
CLEC1B

C-type lectin domain family 1, member B

chr6_-_133078894 2.387 NM_001242350
NM_004665
VNN2

vanin 2

chr13_-_41556188 2.351 ELF1
E74-like factor 1 (ets domain transcription factor)
chr11_+_122709205 2.298 NM_019604
CRTAM
cytotoxic and regulatory T cell molecule
chr8_-_101965601 2.254 NM_003406
YWHAZ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
chr5_+_75699003 2.163 NM_006633
IQGAP2
IQ motif containing GTPase activating protein 2
chr16_-_3627353 2.155 NM_178844
NLRC3
NLR family, CARD domain containing 3
chr7_+_141695678 2.136 NM_004668
MGAM
maltase-glucoamylase (alpha-glucosidase)
chr19_+_18208596 2.133 NM_015016
MAST3
microtubule associated serine/threonine kinase 3
chr1_-_225616556 2.128 NM_194442
LBR
lamin B receptor
chr6_+_29759682 2.094 NM_001207043
LOC554223
histocompatibility antigen-related
chr19_-_4916814 2.083


chr11_+_64937624 2.054 NM_001008778
SPDYC
speedy homolog C (Xenopus laevis)
chr4_-_123542165 2.053 NM_001207006
NM_021803
IL21

interleukin 21

chr1_-_32385258 2.006 NM_001195100
NM_001195101
PTP4A2

protein tyrosine phosphatase type IVA, member 2

chr2_+_152214105 1.980 NM_007115
TNFAIP6
tumor necrosis factor, alpha-induced protein 6
chr14_-_106725620 1.980 IGHV4-31
IGHV3-23
IGHA1
IGHG1
IGHM
immunoglobulin heavy variable 4-31
immunoglobulin heavy variable 3-23
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant mu
chr5_-_39203061 1.960 FYB
FYN binding protein
chr18_+_21572736 1.959 NM_153211
TTC39C
tetratricopeptide repeat domain 39C
chr1_+_158801105 1.914 NM_002432
MNDA
myeloid cell nuclear differentiation antigen
chr1_-_8003224 1.867 NM_001561
TNFRSF9
tumor necrosis factor receptor superfamily, member 9
chr4_+_74347461 1.785 NM_001133
AFM
afamin
chr12_+_47610051 1.768 NM_138371
FAM113B
family with sequence similarity 113, member B
chr1_-_20445991 1.749 NM_012400
PLA2G2D
phospholipase A2, group IID
chr16_-_11680756 1.747 NM_001136472
NM_001136473
LITAF

lipopolysaccharide-induced TNF factor

chr3_+_63884074 1.694 NM_001177387
ATXN7
ataxin 7
chr1_+_84609987 1.693 PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr19_+_17638064 1.692 FAM129C
family with sequence similarity 129, member C
chr10_-_101841593 1.682 NM_001308
CPN1
carboxypeptidase N, polypeptide 1
chr3_+_46283871 1.672 NM_001164680
NM_001837
NM_178328
NM_178329
CCR3



chemokine (C-C motif) receptor 3



chr2_-_20527120 1.666 NM_015317
PUM2
pumilio homolog 2 (Drosophila)
chr5_+_65372744 1.660 ERBB2IP
erbb2 interacting protein
chr13_-_41593491 1.652 NM_172373
ELF1
E74-like factor 1 (ets domain transcription factor)
chr6_+_42897236 1.638 CNPY3
canopy 3 homolog (zebrafish)
chr10_-_32667543 1.623 EPC1
enhancer of polycomb homolog 1 (Drosophila)
chr6_-_31560497 1.600 NM_001145466
NM_001145467
NM_147130
NCR3


natural cytotoxicity triggering receptor 3


chr4_+_69681709 1.587 NM_001075
NM_001144767
UGT2B10

UDP glucuronosyltransferase 2 family, polypeptide B10

chr11_-_73693820 1.583 UCP2
uncoupling protein 2 (mitochondrial, proton carrier)
chr4_+_74270832 1.583 ALB
albumin
chr5_-_147162056 1.546 JAKMIP2
janus kinase and microtubule interacting protein 2
chr2_-_231789940 1.522 NM_005683
GPR55
G protein-coupled receptor 55
chr6_-_53213747 1.517 NM_001242828
NM_001242830
NM_001242831
NM_021814
ELOVL5



ELOVL fatty acid elongase 5



chr12_+_9980076 1.507 NM_016523
KLRF1
killer cell lectin-like receptor subfamily F, member 1
chr16_+_81812897 1.504 NM_002661
PLCG2
phospholipase C, gamma 2 (phosphatidylinositol-specific)
chr16_-_28621279 1.498 NM_001055
NM_177529
SULT1A1

sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1

chrX_+_1387692 1.498 NM_001161529
NM_001161531
NM_001161532
NM_006140
NM_172245
NM_172246
NM_172249
CSF2RA






colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)






chr22_+_23029175 1.494 IGLV3-25
immunoglobulin lambda variable 3-25
chr16_+_81812899 1.493 PLCG2
phospholipase C, gamma 2 (phosphatidylinositol-specific)
chr8_-_37727937 1.491 RAB11FIP1
RAB11 family interacting protein 1 (class I)
chr9_+_6720862 1.477 NM_001146696
KDM4C
lysine (K)-specific demethylase 4C
chr22_-_36556781 1.475 NM_145640
APOL3
apolipoprotein L, 3
chr19_-_6670078 1.466 TNFSF14
tumor necrosis factor (ligand) superfamily, member 14
chr4_-_39033981 1.462 NM_024943
TMEM156
transmembrane protein 156
chr14_-_60632019 1.454 DHRS7
dehydrogenase/reductase (SDR family) member 7
chr7_+_116451073 1.454 CAPZA2
capping protein (actin filament) muscle Z-line, alpha 2
chr21_-_19775958 1.447 NM_002772
TMPRSS15
transmembrane protease, serine 15
chr4_+_74719012 1.443 NM_002620
PF4V1
platelet factor 4 variant 1
chrY_+_1337692 1.417 NM_001161529
NM_001161531
NM_001161532
NM_006140
NM_172245
NM_172246
NM_172249
CSF2RA






colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)






chr13_-_41556360 1.410 NM_001145353
ELF1
E74-like factor 1 (ets domain transcription factor)
chr19_+_47813074 1.389 NM_001736
C5AR1
complement component 5a receptor 1
chr3_-_32023237 1.329 NM_001174060
NM_017784
OSBPL10

oxysterol binding protein-like 10

chr12_+_10457044 1.325 NM_001114396
KLRD1
killer cell lectin-like receptor subfamily D, member 1
chr19_-_13617037 1.320 NM_000068
NM_001127221
NM_001127222
NM_001174080
NM_023035
CACNA1A




calcium channel, voltage-dependent, P/Q type, alpha 1A subunit




chr19_+_55174425 1.319 LILRB4
leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4
chr7_+_77469446 1.300 NM_001127357
NM_001127359
NM_020432
PHTF2


putative homeodomain transcription factor 2


chr13_-_41593405 1.299 ELF1
E74-like factor 1 (ets domain transcription factor)
chr4_+_15704691 1.294 BST1
bone marrow stromal cell antigen 1
chr13_+_31309644 1.290 NM_001629
ALOX5AP
arachidonate 5-lipoxygenase-activating protein
chr6_-_32977351 1.275 NM_002119
HLA-DOA
major histocompatibility complex, class II, DO alpha
chr12_-_27235454 1.260 NM_001080406
C12orf71
chromosome 12 open reading frame 71
chr13_-_46742678 1.256 LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr6_-_33756905 1.245 NM_181336
LEMD2
LEM domain containing 2
chr19_+_22235253 1.240 NM_033468
ZNF257
zinc finger protein 257
chr19_-_23869939 1.239 NM_138330
ZNF675
zinc finger protein 675
chr7_+_55433140 1.238 NM_018697
LANCL2
LanC lantibiotic synthetase component C-like 2 (bacterial)
chr6_+_36210944 1.233 NM_173676
NM_001145716
PNPLA1

patatin-like phospholipase domain containing 1

chr13_-_48987017 1.228 LPAR6
lysophosphatidic acid receptor 6
chr13_+_50202434 1.224 NM_138450
ARL11
ADP-ribosylation factor-like 11
chr4_+_54292035 1.205 FIP1L1
FIP1 like 1 (S. cerevisiae)
chr10_+_97471535 1.204 NM_001098175
ENTPD1
ectonucleoside triphosphate diphosphohydrolase 1
chr4_+_109571732 1.198 NM_021227
OSTC
oligosaccharyltransferase complex subunit
chr2_-_119605758 1.189 NM_001426
EN1
engrailed homeobox 1
chr2_-_214015053 1.169 NM_016260
IKZF2
IKAROS family zinc finger 2 (Helios)
chr14_-_106452693 1.165 IGHG1
immunoglobulin heavy constant gamma 1 (G1m marker)
chr11_+_5641173 1.139 NM_001003827
TRIM34
tripartite motif containing 34
chr7_+_76109826 1.135 NM_001102596
DTX2
deltex homolog 2 (Drosophila)
chr2_+_68592317 1.135 NM_002664
PLEK
pleckstrin
chr7_-_38375172 1.126 TRGV7
T cell receptor gamma variable 7 (pseudogene)
chr22_+_23010757 1.119


chr15_-_50411405 1.116 NM_024837
ATP8B4
ATPase, class I, type 8B, member 4
chr9_+_117373622 1.115 NM_153045
C9orf91
chromosome 9 open reading frame 91
chr1_-_115053758 1.096 NM_015906
NM_033020
TRIM33

tripartite motif containing 33

chr19_-_58892382 1.094 NM_001129730
NM_138466
ZNF837

zinc finger protein 837

chr16_+_10522724 1.087 NM_024997
ATF7IP2
activating transcription factor 7 interacting protein 2
chr5_-_94224601 1.069 MCTP1
multiple C2 domains, transmembrane 1
chr11_-_64727608 1.059 NM_001037225
C11orf85
chromosome 11 open reading frame 85
chr2_+_135596185 1.052 NM_138326
ACMSD
aminocarboxymuconate semialdehyde decarboxylase
chr4_+_74606222 1.046 NM_000584
IL8
interleukin 8
chr7_-_150329735 1.041 NM_001244071
NM_001244072
NM_024711
GIMAP6


GTPase, IMAP family member 6


chr4_+_170581212 1.040 NM_001243374
CLCN3
chloride channel 3
chr11_-_47510518 1.039 NM_001025596
NM_001172640
CELF1

CUGBP, Elav-like family member 1

chr6_+_42897184 1.037 CNPY3
canopy 3 homolog (zebrafish)
chr6_-_66417069 1.006 NM_001142800
NM_001142801
EYS

eyes shut homolog (Drosophila)

chr1_+_84609941 1.006 NM_182948
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr10_+_7745354 1.005 ITIH2
inter-alpha-trypsin inhibitor heavy chain 2
chr17_+_42422665 1.004 GRN
granulin
chr13_-_48987247 1.004 LPAR6
lysophosphatidic acid receptor 6
chr8_-_66701175 0.989 NM_002603
PDE7A
phosphodiesterase 7A
chr7_-_77045706 0.988 NM_017439
PION
pigeon homolog (Drosophila)
chr2_-_176948689 0.977 NM_001080458
EVX2
even-skipped homeobox 2
chr16_-_1494489 0.970 NM_001143980
CCDC154
coiled-coil domain containing 154
chr4_+_15704572 0.964 NM_004334
BST1
bone marrow stromal cell antigen 1
chr1_-_160492982 0.958 NM_001184714
NM_001184715
NM_001184716
NM_052931
SLAMF6



SLAM family member 6



chr12_-_46357949 0.955


chr5_-_94417185 0.949 MCTP1
multiple C2 domains, transmembrane 1
chr16_-_11680146 0.949 NM_004862
LITAF
lipopolysaccharide-induced TNF factor
chr12_-_56753912 0.945 STAT2
signal transducer and activator of transcription 2, 113kDa
chr14_-_60632058 0.943 NM_016029
DHRS7
dehydrogenase/reductase (SDR family) member 7
chr21_-_35884503 0.942 KCNE1
potassium voltage-gated channel, Isk-related family, member 1
chr6_+_26365397 0.933 NM_001197247
NM_001197249
NM_007047
NM_001197248
BTN3A2



butyrophilin, subfamily 3, member A2



chr10_+_7745341 0.929 ITIH2
inter-alpha-trypsin inhibitor heavy chain 2
chr19_-_48752921 0.914 NM_001184901
NM_001184903
NM_014959
CARD8


caspase recruitment domain family, member 8


chr14_+_39734475 0.911 NM_203354
CTAGE5
CTAGE family, member 5
chr1_+_241695433 0.906 NM_003679
KMO
kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
chr12_+_20963637 0.903 NM_019844
SLCO1B3
solute carrier organic anion transporter family, member 1B3
chr16_-_11375094 0.902 NM_002761
PRM1
protamine 1
chr4_+_40198526 0.896 NM_004310
RHOH
ras homolog gene family, member H
chr22_+_35796294 0.891 MCM5
minichromosome maintenance complex component 5
chr10_-_50342052 0.890 NM_001164484
FAM170B
family with sequence similarity 170, member B
chr12_-_30848805 0.888 NM_006390
IPO8
importin 8
chr2_+_68592432 0.888 PLEK
pleckstrin
chr4_+_109571780 0.887 OSTC
oligosaccharyltransferase complex subunit
chr2_-_37544165 0.882 NM_005813
PRKD3
protein kinase D3
chr12_-_8088629 0.879 NM_006931
SLC2A3
solute carrier family 2 (facilitated glucose transporter), member 3
chr16_+_66586518 0.868 CKLF
chemokine-like factor
chr5_-_156390206 0.864 NM_001146726
NM_138379
TIMD4

T-cell immunoglobulin and mucin domain containing 4

chr17_+_75181294 0.863 NM_001144001
SEC14L1
SEC14-like 1 (S. cerevisiae)
chr4_+_70146216 0.858 NM_001207004
NM_053039
UGT2B28

UDP glucuronosyltransferase 2 family, polypeptide B28

chr2_+_172821874 0.845 HAT1
histone acetyltransferase 1
chr19_-_9415794 0.844 NM_198535
ZNF266
ZNF699
zinc finger protein 266
zinc finger protein 699
chr7_-_38389575 0.842 TRGV5
T cell receptor gamma variable 5
chr1_-_89591685 0.841 NM_004120
GBP2
guanylate binding protein 2, interferon-inducible
chr10_+_7745325 0.839 ITIH2
inter-alpha-trypsin inhibitor heavy chain 2
chr3_+_132036210 0.837 NM_001099
NM_001134194
ACPP

acid phosphatase, prostate

chr17_-_18177716 0.833 TOP3A
topoisomerase (DNA) III alpha
chr19_-_48759141 0.833 NM_001184902
NM_001184904
CARD8

caspase recruitment domain family, member 8

chr3_-_151102536 0.823 NM_022788
P2RY12
purinergic receptor P2Y, G-protein coupled, 12
chr1_+_43282775 0.816 NM_001017922
ERMAP
erythroblast membrane-associated protein (Scianna blood group)
chr10_+_7745284 0.814 ITIH2
inter-alpha-trypsin inhibitor heavy chain 2
chr4_-_103245468 0.814 NM_001135148
SLC39A8
solute carrier family 39 (zinc transporter), member 8
chr3_+_151591428 0.813 NM_033050
SUCNR1
succinate receptor 1
chr6_+_119215240 0.805 NM_014034
ASF1A
ASF1 anti-silencing function 1 homolog A (S. cerevisiae)
chr4_-_69886112 0.797 NM_001075
NM_001144767
UGT2B10

UDP glucuronosyltransferase 2 family, polypeptide B10

chr19_-_6591012 0.797 CD70
CD70 molecule
chrX_-_131573638 0.795 NM_018388
NM_133486
MBNL3

muscleblind-like 3 (Drosophila)

chr4_+_155484131 0.789 NM_001184741
NM_005141
FGB

fibrinogen beta chain

chr6_+_4890225 0.785 NM_001143971
CDYL
chromodomain protein, Y-like
chr22_-_17700265 0.783 CECR1
cat eye syndrome chromosome region, candidate 1
chr7_-_64467006 0.772 NM_001007253
ERV3-1
endogenous retrovirus group 3, member 1

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
4.08 1.21e-09 GO:0002376 immune system process
5.05 1.08e-08 GO:0006955 immune response
5.23 1.41e-08 GO:0002682 regulation of immune system process
4.06 2.42e-06 GO:0009611 response to wounding
4.10 1.00e-05 GO:0006952 defense response
5.34 3.18e-05 GO:0050776 regulation of immune response
6.72 4.48e-05 GO:0006954 inflammatory response
4.84 1.24e-04 GO:0001775 cell activation
5.06 1.74e-04 GO:0002684 positive regulation of immune system process
3.77 1.83e-04 GO:0048584 positive regulation of response to stimulus
1.68 1.84e-04 GO:0050896 response to stimulus
2.64 2.25e-04 GO:0007166 cell surface receptor linked signaling pathway
6.09 4.22e-04 GO:0050778 positive regulation of immune response
2.04 4.53e-04 GO:0007165 signal transduction
1.89 5.83e-04 GO:0051716 cellular response to stimulus
6.57 5.94e-04 GO:0045321 leukocyte activation
2.22 2.06e-03 GO:0006950 response to stress
2.10 3.46e-03 GO:0048518 positive regulation of biological process
2.37 5.01e-03 GO:0048583 regulation of response to stimulus
9.52 5.61e-03 GO:0002429 immune response-activating cell surface receptor signaling pathway
5.80 5.75e-03 GO:0050865 regulation of cell activation
1.85 7.00e-03 GO:0023052 signaling
9.16 7.25e-03 GO:0002768 immune response-regulating cell surface receptor signaling pathway
15.97 9.17e-03 GO:0030595 leukocyte chemotaxis
5.98 1.29e-02 GO:0051249 regulation of lymphocyte activation
45.77 1.93e-02 GO:0042119 neutrophil activation
13.21 2.35e-02 GO:0048520 positive regulation of behavior
5.43 2.77e-02 GO:0002694 regulation of leukocyte activation
12.72 2.83e-02 GO:0006968 cellular defense response
12.49 3.09e-02 GO:0060326 cell chemotaxis
6.14 3.12e-02 GO:0050867 positive regulation of cell activation
8.87 3.77e-02 GO:0050851 antigen receptor-mediated signaling pathway
17.72 4.56e-02 GO:0002690 positive regulation of leukocyte chemotaxis

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
68.65 3.56e-02 GO:0005639 integral to nuclear inner membrane
68.65 3.56e-02 GO:0031229 intrinsic to nuclear inner membrane

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
2.44 9.80e-04 GO:0004872 receptor activity
2.21 2.14e-03 GO:0004871 signal transducer activity
2.21 2.14e-03 GO:0060089 molecular transducer activity
13.47 4.86e-03 GO:0042379 chemokine receptor binding
4.15 1.04e-02 GO:0030246 carbohydrate binding
13.74 2.87e-02 GO:0003823 antigen binding
68.65 4.49e-02 GO:0048020 CCR chemokine receptor binding
11.95 4.95e-02 GO:0008009 chemokine activity
5.35 4.99e-02 GO:0005126 cytokine receptor binding