Motif ID: AR.p2

Z-value: 3.543


Transcription factors associated with AR.p2:

Gene SymbolEntrez IDGene Name
AR 367 androgen receptor

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
ARhg19_v1_chrX_+_66766350_66766392-0.494.0e-03Click!


Activity profile for motif AR.p2.

activity profile for motif AR.p2


Sorted Z-values histogram for motif AR.p2

Sorted Z-values for motif AR.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of AR.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr14_-_107131217 50.008 IGHA1
immunoglobulin heavy constant alpha 1
chr14_-_106552313 44.816 IGHA1
IGHD
IGHG1
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant delta
immunoglobulin heavy constant gamma 1 (G1m marker)
chr14_-_106691698 42.784


chr14_-_106692107 39.505 IGHV4-31
IGHA1
IGHD
IGHG1
IGHG3
immunoglobulin heavy variable 4-31
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant delta
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant gamma 3 (G3m marker)
chr14_-_106573348 38.532 IGHV4-31
IGHA1
IGHA2
IGHG1
IGHG3
IGHM
immunoglobulin heavy variable 4-31
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant alpha 2 (A2m marker)
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant gamma 3 (G3m marker)
immunoglobulin heavy constant mu
chr14_-_107113943 38.185 IGHA1
IGHG1
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
chr14_-_107211131 35.405 IGHG1
immunoglobulin heavy constant gamma 1 (G1m marker)
chr14_-_107048697 34.638 IGHG1
immunoglobulin heavy constant gamma 1 (G1m marker)
chr14_-_106518424 34.633 IGH@
IGHA1
IGHG1
IGHG2
IGHM
immunoglobulin heavy locus
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant gamma 2 (G2m marker)
immunoglobulin heavy constant mu
chr14_-_106926393 34.460 IGHA1
IGHG1
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
chr14_-_107199126 33.765 IGHG3
immunoglobulin heavy constant gamma 3 (G3m marker)
chr14_-_106725620 31.802 IGHV4-31
IGHV3-23
IGHA1
IGHG1
IGHM
immunoglobulin heavy variable 4-31
immunoglobulin heavy variable 3-23
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant mu
chr14_-_106586333 30.574 IGHV4-31
immunoglobulin heavy variable 4-31
chr14_-_106994001 28.324 IGHV3-48
IGH@
IGHA1
IGHM
immunoglobulin heavy variable 3-48
immunoglobulin heavy locus
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant mu
chr14_-_107218786 26.223 IGHA1
IGHG1
IGHM
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant mu
chr1_-_1149495 20.811 NM_003327
TNFRSF4
tumor necrosis factor receptor superfamily, member 4
chr14_-_107099379 20.106 IGHG1
IGHG3
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant gamma 3 (G3m marker)
chr14_-_106725232 15.470 ZCWPW2
IGHV3-23
IGKV3-20
IGK@
zinc finger, CW type with PWWP domain 2
immunoglobulin heavy variable 3-23
immunoglobulin kappa variable 3-20
immunoglobulin kappa locus
chr1_-_150738232 14.272 CTSS
cathepsin S
chr7_+_150147936 9.873 NM_175571
GIMAP8
GTPase, IMAP family member 8
chr1_-_150738255 9.761 CTSS
cathepsin S
chr19_+_17638064 9.448 FAM129C
family with sequence similarity 129, member C
chr7_+_150147882 8.811 GIMAP8
GTPase, IMAP family member 8
chr14_-_106791054 7.275 IGHV4-31
IGHV3-30
IGHA1
IGHD
IGHG1
IGHG2
IGHG3
IGHM
SCFV
immunoglobulin heavy variable 4-31
immunoglobulin heavy variable 3-30
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant delta
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant gamma 2 (G2m marker)
immunoglobulin heavy constant gamma 3 (G3m marker)
immunoglobulin heavy constant mu
single-chain Fv fragment
chr1_-_150738292 7.141 NM_001199739
NM_004079
CTSS

cathepsin S

chr14_-_106610338 6.172 IGHV4-31
IGHG1
immunoglobulin heavy variable 4-31
immunoglobulin heavy constant gamma 1 (G1m marker)
chr1_-_202129731 5.933 PTPN7
protein tyrosine phosphatase, non-receptor type 7
chr6_-_26235160 5.730 NM_005320
HIST1H1D
histone cluster 1, H1d
chr1_-_156786500 5.340 NM_001161441
NM_001161442
NM_001161444
NM_003975
SH2D2A



SH2 domain containing 2A



chr1_-_202129705 5.228 PTPN7
protein tyrosine phosphatase, non-receptor type 7
chr6_+_31638727 5.007 NM_021221
LY6G5B
lymphocyte antigen 6 complex, locus G5B
chr12_+_113416267 4.740 NM_001032731
NM_002535
NM_016817
OAS2


2'-5'-oligoadenylate synthetase 2, 69/71kDa


chr19_-_54876671 4.709 NM_002287
NM_021706
LAIR1

leukocyte-associated immunoglobulin-like receptor 1

chr9_-_117156684 4.135 NM_030767
AKNA
AT-hook transcription factor
chr3_+_52279742 4.112 NM_144641
PPM1M
protein phosphatase, Mg2+/Mn2+ dependent, 1M
chr3_-_111314181 3.386 NM_024508
ZBED2
zinc finger, BED-type containing 2
chr1_-_27953046 3.363 NM_001042729
FGR
Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog
chr2_+_135011829 3.193 NM_002410
MGAT5
mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase
chr15_-_90349819 3.052 ANPEP
alanyl (membrane) aminopeptidase
chr16_-_67970734 2.999 NM_002801
PSMB10
proteasome (prosome, macropain) subunit, beta type, 10
chr1_+_22979681 2.917 NM_000491
C1QB
complement component 1, q subcomponent, B chain
chr2_+_87755059 2.861 LINC00152
long intergenic non-protein coding RNA 152
chr11_+_63974144 2.828 NM_031471
NM_178443
FERMT3

fermitin family member 3

chr19_+_39899749 2.749


chr2_-_109605668 2.724 NM_022336
EDAR
ectodysplasin A receptor
chr1_+_151129104 2.517 NM_001204848
NM_024575
TNFAIP8L2-SCNM1
TNFAIP8L2
TNFAIP8L2-SCNM1 readthrough
tumor necrosis factor, alpha-induced protein 8-like 2
chr9_+_95736717 2.308 NM_033086
FGD3
FYVE, RhoGEF and PH domain containing 3
chr6_-_6320897 2.023 NM_000129
F13A1
coagulation factor XIII, A1 polypeptide
chr21_-_35884503 1.946 KCNE1
potassium voltage-gated channel, Isk-related family, member 1
chr6_-_6320875 1.922 F13A1
coagulation factor XIII, A1 polypeptide
chr8_-_23177481 1.919 LOXL2
lysyl oxidase-like 2
chr5_-_176937337 1.874 NM_001144875
NM_001144876
DOK3

docking protein 3

chr7_+_142960588 1.855 GSTK1
glutathione S-transferase kappa 1
chr1_+_12185955 1.824 NM_152942
TNFRSF8
tumor necrosis factor receptor superfamily, member 8
chr4_-_42154576 1.823 BEND4
BEN domain containing 4
chr1_+_181003143 1.671 MR1
major histocompatibility complex, class I-related
chr1_-_156785938 1.653 NM_001161443
SH2D2A
SH2 domain containing 2A
chr11_+_63974190 1.634 FERMT3
fermitin family member 3
chr12_-_91505541 1.631 NM_002345
LUM
lumican
chr10_+_70847817 1.599 NM_002727
SRGN
serglycin
chr19_-_41934634 1.481 NM_198540
B3GNT8
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8
chr15_-_40398286 1.442 NM_001003942
NM_001003943
BMF

Bcl2 modifying factor

chr7_-_131833385 1.424 PLXNA4
plexin A4
chr19_+_55417507 1.411 NM_001145457
NM_001145458
NM_001242356
NM_001242357
NM_004829
NCR1




natural cytotoxicity triggering receptor 1




chr17_-_48264039 1.328 COL1A1
collagen, type I, alpha 1
chr2_+_241544819 1.326 NM_001195381
NM_001195382
GPR35

G protein-coupled receptor 35

chr7_+_142960502 1.237 NM_001143679
NM_001143680
NM_001143681
NM_015917
GSTK1



glutathione S-transferase kappa 1



chr19_+_50472856 1.184 SIGLEC16
sialic acid binding Ig-like lectin 16 (gene/pseudogene)
chr14_+_21156922 1.181 NM_001097577
NM_194431
ANG
RNASE4
angiogenin, ribonuclease, RNase A family, 5
ribonuclease, RNase A family, 4
chr10_+_75673346 1.038 PLAU
plasminogen activator, urokinase
chr6_-_30899926 1.005 NM_205854
SFTA2
surfactant associated 2
chr5_-_149792276 0.953 CD74
CD74 molecule, major histocompatibility complex, class II invariant chain
chr12_-_53575121 0.877 CSAD
cysteine sulfinic acid decarboxylase
chr2_-_56412904 0.853 LOC100129434
uncharacterized LOC100129434
chr4_-_10686314 0.799 NM_052964
CLNK
cytokine-dependent hematopoietic cell linker
chr3_+_46448678 0.794 NM_003965
NM_001130910
CCRL2

chemokine (C-C motif) receptor-like 2

chrX_+_118602362 0.783 NM_001152
SLC25A5
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5
chr2_-_231789940 0.775 NM_005683
GPR55
G protein-coupled receptor 55
chr1_-_104239071 0.738 NM_001008221
AMY1A
amylase, alpha 1A (salivary)
chr1_-_145715561 0.733 NM_007053
CD160
CD160 molecule
chr19_-_15391261 0.731 NM_014299
NM_058243
BRD4

bromodomain containing 4

chr14_-_77542533 0.718


chr11_-_72433379 0.714 NM_001135190
NM_015242
ARAP1

ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1

chr2_+_231280906 0.706 SP100
SP100 nuclear antigen
chr11_+_117070039 0.676 NM_001001522
NM_003186
TAGLN

transgelin

chr1_+_104198140 0.647 NM_001008221
AMY1A
amylase, alpha 1A (salivary)
chr17_-_40346427 0.592 NM_001142622
NM_001142623
NM_032484
GHDC


GH3 domain containing


chr4_+_166128823 0.540 KLHL2
kelch-like 2, Mayven (Drosophila)
chr10_+_102758072 0.526 LZTS2
leucine zipper, putative tumor suppressor 2
chr15_+_65914269 0.525 NM_004727
SLC24A1
solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
chr16_-_67970651 0.517 PSMB10
proteasome (prosome, macropain) subunit, beta type, 10
chr1_+_204042191 0.463 NM_005686
SOX13
SRY (sex determining region Y)-box 13
chr9_-_124984018 0.453 NM_001242335
LHX6
LIM homeobox 6
chr4_+_71494460 0.413 NM_031889
ENAM
enamelin
chr3_-_152058778 0.384 NM_001123228
TMEM14E
transmembrane protein 14E
chr9_+_27524311 0.374 NM_020124
IFNK
interferon, kappa
chr15_+_85291802 0.358 NM_014630
ZNF592
zinc finger protein 592
chr1_-_153588789 0.355 NM_020672
S100A14
S100 calcium binding protein A14
chr22_-_39150952 0.331 SUN2
Sad1 and UNC84 domain containing 2
chr7_+_87563432 0.323 NM_004194
NM_016351
NM_021721
NM_021722
NM_021723
ADAM22




ADAM metallopeptidase domain 22




chrX_+_118602391 0.322 SLC25A5
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5
chr1_+_104292278 0.316 NM_001008221
AMY1A
amylase, alpha 1A (salivary)
chr18_+_12991329 0.297 NM_032142
CEP192
centrosomal protein 192kDa
chr16_-_787888 0.270 NARFL
nuclear prelamin A recognition factor-like
chr2_-_109605616 0.251 EDAR
ectodysplasin A receptor
chr12_+_21525801 0.244 NM_000415
IAPP
islet amyloid polypeptide
chr12_+_52347163 0.222 NM_020327
ACVR1B
activin A receptor, type IB
chr6_+_18387580 0.210 NM_182757
RNF144B
ring finger protein 144B
chr16_-_67977956 0.199 NM_000229
LCAT
lecithin-cholesterol acyltransferase
chr8_+_62200524 0.159 NM_173519
CLVS1
clavesin 1
chr12_-_7245048 0.141 C1R
complement component 1, r subcomponent
chr11_-_65638672 0.139 EFEMP2
EGF containing fibulin-like extracellular matrix protein 2
chr12_+_51318515 0.110 NM_014033
METTL7A
methyltransferase like 7A
chr2_+_242577098 0.089 ATG4B
ATG4 autophagy related 4 homolog B (S. cerevisiae)
chr6_-_154831788 0.062 CNKSR3
CNKSR family member 3
chr11_+_113659924 0.051 LOC390251
SH3-domain GRB2-like 1 pseudogene
chr17_-_3496122 0.036 NM_080706
TRPV1
transient receptor potential cation channel, subfamily V, member 1
chr2_+_242576975 0.017 NM_013325
NM_178326
ATG4B

ATG4 autophagy related 4 homolog B (S. cerevisiae)

chr11_-_7847518 0.013 NM_153445
OR5P3
olfactory receptor, family 5, subfamily P, member 3
chr6_+_29079586 0.008 NM_001005216
OR2J3
olfactory receptor, family 2, subfamily J, member 3

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
6.74 9.13e-06 GO:0006955 immune response
4.76 6.28e-05 GO:0002376 immune system process

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
3.16 5.83e-04 GO:0005576 extracellular region
20.32 3.02e-02 GO:0031983 vesicle lumen
63.99 3.04e-02 GO:0005583 fibrillar collagen

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
61.59 8.29e-10 GO:0003823 antigen binding
54.15 3.29e-02 GO:0005035 death receptor activity