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Motif ID: ATF6.p2

Z-value: 1.359

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr17_-_46688362	3.943	NM_004502	HOXB7	homeobox B7
chr17_-_46688279	3.791		HOXB7	homeobox B7
chr7_-_73184535	3.248	NM_001306	CLDN3	claudin 3
chr17_-_46687925	2.897		HOXB7	homeobox B7
chr19_+_16187266	2.556		TPM4	tropomyosin 4
chr14_-_38064440	2.502	NM_004496	FOXA1	forkhead box A1
chr20_-_44420538	2.495	NM_080614	WFDC3	WAP four-disulfide core domain 3
chr7_+_94024201	2.470		COL1A2	collagen, type I, alpha 2
chr19_+_16187315	2.465		TPM4	tropomyosin 4
chr19_+_16187306	2.238		TPM4	tropomyosin 4
chr7_-_27224762	2.138	NM_005523	HOXA11	homeobox A11
chr8_-_95274540	2.074	NM_005261 NM_181702	GEM	GTP binding protein overexpressed in skeletal muscle
chr2_+_176987412	2.050	NM_014213	HOXD9	homeobox D9
chr7_-_37956377	2.015		SFRP4	secreted frizzled-related protein 4
chr3_+_100211554	2.005		TMEM45A	transmembrane protein 45A
chr7_-_37956515	1.958	NM_003014	SFRP4	secreted frizzled-related protein 4
chr1_+_151483861	1.952	NM_020770	CGN	cingulin
chr1_+_156030965	1.919	NM_020387	RAB25	RAB25, member RAS oncogene family
chr6_+_151561094	1.903	NM_005100	AKAP12	A kinase (PRKA) anchor protein 12
chr19_+_16187047	1.890	NM_003290	TPM4	tropomyosin 4
chr1_+_233749749	1.883	NM_002245	KCNK1	potassium channel, subfamily K, member 1
chr12_+_56552141	1.799		MYL6	myosin, light chain 6, alkali, smooth muscle and non-muscle
chr11_+_43963809	1.761	NM_001145033	C11orf96	chromosome 11 open reading frame 96
chr3_+_100211408	1.747	NM_018004	TMEM45A	transmembrane protein 45A
chr7_+_27225009	1.744		HOXA11-AS1	HOXA11 antisense RNA 1 (non-protein coding)
chr6_-_31846816	1.729	NM_001178044 NM_025257	SLC44A4	solute carrier family 44, member 4
chr19_-_4670375	1.652	NM_019107	C19orf10	chromosome 19 open reading frame 10
chr5_-_44388666	1.646	NM_004465	FGF10	fibroblast growth factor 10
chr6_-_31846766	1.646		SLC44A4	solute carrier family 44, member 4
chr17_-_46655544	1.606	NM_024015	HOXB4	homeobox B4
chr2_-_28113954	1.561		LOC100302650	uncharacterized LOC100302650
chr8_+_120220554	1.559	NM_052886	MAL2	mal, T-cell differentiation protein 2 (gene/pseudogene)
chr7_+_94023872	1.551	NM_000089	COL1A2	collagen, type I, alpha 2
chr8_-_95274520	1.518		GEM	GTP binding protein overexpressed in skeletal muscle
chr7_-_19157262	1.495	NM_000474	TWIST1	twist homolog 1 (Drosophila)
chr3_-_150263899	1.469		SERP1	stress-associated endoplasmic reticulum protein 1
chr12_+_112451151	1.465	NM_001034025 NM_006817	ERP29	endoplasmic reticulum protein 29
chr19_-_4670332	1.459		C19orf10	chromosome 19 open reading frame 10
chr17_+_59529778	1.445		TBX4	T-box 4
chr22_+_38864015	1.435	NM_006855 NM_016657	KDELR3	KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
chr17_-_13505217	1.435	NM_006042	HS3ST3A1	heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1
chr20_-_22564893	1.413		FOXA2	forkhead box A2
chr1_+_32712817	1.412	NM_032648	FAM167B	family with sequence similarity 167, member B
chr19_+_38810461	1.391	NM_004823	KCNK6	potassium channel, subfamily K, member 6
chr1_-_173837122	1.355		GAS5	growth arrest-specific 5 (non-protein coding)
chr3_-_57583153	1.348	NM_001660	ARF4	ADP-ribosylation factor 4
chr3_-_73673978	1.344	NM_015009	PDZRN3	PDZ domain containing ring finger 3
chr14_+_101292451	1.312		MEG3	maternally expressed 3 (non-protein coding)
chr1_+_19970674	1.309	NM_005380	NBL1	neuroblastoma, suppression of tumorigenicity 1
chr3_-_57583090	1.309		ARF4	ADP-ribosylation factor 4
chr17_-_46703613	1.306	NM_024017	HOXB9	homeobox B9
chr3_-_57583080	1.301		ARF4	ADP-ribosylation factor 4
chr3_-_156877882	1.299		CCNL1	cyclin L1
chr2_-_216300770	1.294	NM_002026 NM_054034 NM_212474 NM_212476 NM_212478 NM_212482	FN1	fibronectin 1
chr2_-_216300444	1.287		FN1	fibronectin 1
chr19_-_5340700	1.284	NM_002850 NM_130853 NM_130854 NM_130855	PTPRS	protein tyrosine phosphatase, receptor type, S
chr14_+_23305913	1.276		MMP14	matrix metallopeptidase 14 (membrane-inserted)
chr2_-_133427624	1.272		LYPD1	LY6/PLAUR domain containing 1
chr21_-_44846927	1.272	NM_173354	SIK1	salt-inducible kinase 1
chr11_-_66610703	1.271
chr14_+_23305907	1.265		MMP14	matrix metallopeptidase 14 (membrane-inserted)
chr19_+_38810751	1.263		KCNK6	potassium channel, subfamily K, member 6
chr4_+_37455551	1.255	NM_001104629	C4orf19	chromosome 4 open reading frame 19
chr19_+_38810540	1.236		KCNK6	potassium channel, subfamily K, member 6
chr2_-_1748285	1.224	NM_012293	PXDN	peroxidasin homolog (Drosophila)
chr6_-_32936230	1.219
chr14_+_103388992	1.213	NM_030943	AMN	amnionless homolog (mouse)
chr19_+_50031232	1.212		RCN3	reticulocalbin 3, EF-hand calcium binding domain
chr8_+_95653272	1.209		ESRP1	epithelial splicing regulatory protein 1
chr11_-_68780667	1.207	NM_001098515 NM_145015	MRGPRF	MAS-related GPR, member F
chr6_-_75915753	1.203		COL12A1	collagen, type XII, alpha 1
chr6_-_31846751	1.201		SLC44A4	solute carrier family 44, member 4
chr13_+_113951537	1.176		LAMP1	lysosomal-associated membrane protein 1
chr3_-_57582866	1.163		ARF4	ADP-ribosylation factor 4
chr10_+_112257624	1.152	NM_004419	DUSP5	dual specificity phosphatase 5
chrX_+_47441802	1.138		TIMP1	TIMP metallopeptidase inhibitor 1
chr1_+_233749917	1.130		KCNK1	potassium channel, subfamily K, member 1
chr18_-_19748928	1.130		LOC100128893	uncharacterized LOC100128893
chr22_+_38597938	1.126	NM_001161572 NM_001161574 NM_012323	MAFF	v-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian)
chr20_-_22565050	1.115	NM_021784	FOXA2	forkhead box A2
chr12_+_112451261	1.109		ERP29	endoplasmic reticulum protein 29
chr4_+_85504056	1.091	NM_001263	CDS1	CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1
chr2_+_28615695	1.083		FOSL2	FOS-like antigen 2
chr11_+_66188474	1.081	NM_178864	NPAS4	neuronal PAS domain protein 4
chr14_-_38064176	1.075		FOXA1	forkhead box A1
chrX_-_100914816	1.070	NM_014782 NM_177949	ARMCX2	armadillo repeat containing, X-linked 2
chr6_-_75915566	1.057	NM_004370 NM_080645	COL12A1	collagen, type XII, alpha 1
chr3_+_139654001	1.045	NM_022131	CLSTN2	calsyntenin 2
chr14_+_24836144	1.038	NM_001136022 NM_001198967	NFATC4	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
chr2_-_97535669	1.028	NM_017789	SEMA4C	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
chr11_-_75921785	1.020		WNT11	wingless-type MMTV integration site family, member 11
chr3_+_193853930	1.018	NM_005524	HES1	hairy and enhancer of split 1, (Drosophila)
chr3_+_193853937	1.018		HES1	hairy and enhancer of split 1, (Drosophila)
chr11_-_35547144	1.002	NM_001001991 NM_015430	PAMR1	peptidase domain containing associated with muscle regeneration 1
chr14_-_106174914	0.999		IGHA1	immunoglobulin heavy constant alpha 1
chr2_+_219745243	0.987	NM_025216	WNT10A	wingless-type MMTV integration site family, member 10A
chr3_-_150264234	0.982		SERP1	stress-associated endoplasmic reticulum protein 1
chrX_+_47441650	0.981	NM_003254	TIMP1	TIMP metallopeptidase inhibitor 1
chr14_+_23305792	0.974	NM_004995	MMP14	matrix metallopeptidase 14 (membrane-inserted)
chr5_+_137801166	0.967		EGR1	early growth response 1
chr3_-_75484091	0.955		FAM86DP	family with sequence similarity 86, member D, pseudogene
chr11_+_69455938	0.953		CCND1	cyclin D1
chr3_+_184097860	0.949	NM_003741	CHRD	chordin
chr6_+_31982538	0.945	NM_001242823 NM_001252204 NM_007293 NM_001002029	LOC100293534 C4A C4B	complement C4-B-like complement component 4A (Rodgers blood group) complement component 4B (Chido blood group)
chr16_-_54320367	0.943	NM_024336	IRX3	iroquois homeobox 3
chr19_-_47290541	0.941	NM_001145144	SLC1A5	solute carrier family 1 (neutral amino acid transporter), member 5
chr8_-_22550708	0.941	NM_004430	EGR3	early growth response 3
chr19_-_10341947	0.931	NM_004230	S1PR2	sphingosine-1-phosphate receptor 2
chr3_-_150264264	0.925		SERP1	stress-associated endoplasmic reticulum protein 1
chr5_+_137801178	0.923	NM_001964	EGR1	early growth response 1
chr20_-_61051025	0.921	NM_080473	GATA5	GATA binding protein 5
chr16_+_4385141	0.921		GLIS2	GLIS family zinc finger 2
chr17_-_40575117	0.918	NM_012232	PTRF	polymerase I and transcript release factor
chr10_-_118032975	0.910	NM_005264	GFRA1	GDNF family receptor alpha 1
chr2_-_288181	0.903	NM_001002919	FAM150B	family with sequence similarity 150, member B
chr12_+_54393876	0.903	NM_006897	HOXC9	homeobox C9
chr19_+_49458129	0.903		BAX	BCL2-associated X protein
chr1_-_235812994	0.894	NM_001098722	GNG4	guanine nucleotide binding protein (G protein), gamma 4
chr3_+_50306578	0.889		SEMA3B	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
chr7_-_6523689	0.879	NM_001100603 NM_006854	KDELR2	KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2
chr11_+_69455884	0.875		CCND1	cyclin D1
chr3_-_124653571	0.868	NM_033049	MUC13	mucin 13, cell surface associated
chr17_-_74533623	0.863	NM_134268	CYGB	cytoglobin
chr1_-_171621750	0.859	NM_000261	MYOC	myocilin, trabecular meshwork inducible glucocorticoid response
chr3_-_150264134	0.850		SERP1	stress-associated endoplasmic reticulum protein 1
chr7_+_65670256	0.847	NM_003596	TPST1	tyrosylprotein sulfotransferase 1
chr16_-_79634610	0.847	NM_001031804 NM_005360	MAF	v-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian)
chr14_+_23305816	0.838		MMP14	matrix metallopeptidase 14 (membrane-inserted)
chr2_+_28615771	0.837	NM_005253	FOSL2	FOS-like antigen 2
chr3_+_122785855	0.835	NM_006810	PDIA5	protein disulfide isomerase family A, member 5
chr7_+_5632435	0.825	NM_003088	FSCN1	fascin homolog 1, actin-bundling protein (Strongylocentrotus purpuratus)
chr17_+_7210929	0.825		EIF5A	eukaryotic translation initiation factor 5A
chr11_-_2018703	0.823		H19	H19, imprinted maternally expressed transcript (non-protein coding)
chr18_+_19749403	0.821	NM_005257	GATA6	GATA binding protein 6
chr6_-_7910278	0.820	NM_001145549	TXNDC5	thioredoxin domain containing 5 (endoplasmic reticulum)
chr9_+_102584136	0.819	NM_006981 NM_173199 NM_173200	NR4A3	nuclear receptor subfamily 4, group A, member 3
chr19_-_55628780	0.819	NM_017607	PPP1R12C	protein phosphatase 1, regulatory subunit 12C
chr7_+_27224163	0.814
chr11_+_69455837	0.808	NM_053056	CCND1	cyclin D1
chr5_-_172198160	0.806	NM_004417	DUSP1	dual specificity phosphatase 1
chr3_-_150264280	0.795	NM_014445	SERP1	stress-associated endoplasmic reticulum protein 1
chr4_+_166299942	0.787	NM_001873	CPE	carboxypeptidase E
chr17_+_7210841	0.787	NM_001970	EIF5A	eukaryotic translation initiation factor 5A
chr19_+_49990864	0.785	NM_012423	RPL13A	ribosomal protein L13a
chr9_+_137533643	0.782	NM_000093	COL5A1	collagen, type V, alpha 1
chr17_+_7211260	0.774	NM_001143761	EIF5A	eukaryotic translation initiation factor 5A
chr17_-_56084656	0.768	NM_001078166 NM_006924	SRSF1	serine/arginine-rich splicing factor 1
chr1_-_62785067	0.765	NM_181712	KANK4	KN motif and ankyrin repeat domains 4
chr5_-_131563481	0.764	NM_001017974 NM_001142598 NM_001142599	P4HA2	prolyl 4-hydroxylase, alpha polypeptide II
chr12_-_114843888	0.763	NM_181486	TBX5	T-box 5
chr12_+_56552044	0.763	NM_021019 NM_079423	MYL6	myosin, light chain 6, alkali, smooth muscle and non-muscle
chr6_-_7910716	0.757	NM_030810	TXNDC5	thioredoxin domain containing 5 (endoplasmic reticulum)
chr16_+_84328400	0.756	NM_021197	WFDC1	WAP four-disulfide core domain 1
chr7_+_5632453	0.741		FSCN1	fascin homolog 1, actin-bundling protein (Strongylocentrotus purpuratus)
chr2_+_176972005	0.741	NM_021192	HOXD11	homeobox D11
chrX_+_153060073	0.734		SSR4	signal sequence receptor, delta
chr9_+_6757636	0.731	NM_001146694 NM_001146695 NM_015061	KDM4C	lysine (K)-specific demethylase 4C
chr14_-_77494974	0.729	NM_024496	IRF2BPL	interferon regulatory factor 2 binding protein-like
chr1_-_20812727	0.726	NM_018584	CAMK2N1	calcium/calmodulin-dependent protein kinase II inhibitor 1
chr17_-_35293920	0.725
chrX_-_100662905	0.725	NM_000169	GLA	galactosidase, alpha
chr19_-_55895602	0.716	NM_001190764	TMEM238	transmembrane protein 238
chr2_+_28615668	0.716		FOSL2	FOS-like antigen 2
chr17_-_31386	0.714	NM_003585	DOC2B	double C2-like domains, beta
chr1_-_16482426	0.713	NM_004431	EPHA2	EPH receptor A2
chr11_+_120081669	0.710	NM_178507	OAF	OAF homolog (Drosophila)
chr19_+_49990849	0.710		RPL13A	ribosomal protein L13a
chr5_+_94890777	0.709	NM_198150	ARSK	arylsulfatase family, member K
chr16_-_82045045	0.706	NM_145168	SDR42E1	short chain dehydrogenase/reductase family 42E, member 1
chr17_+_79885567	0.702		LOC92659	uncharacterized LOC92659
chr4_+_52917440	0.701	NM_145263	SPATA18	spermatogenesis associated 18 homolog (rat)
chr19_+_38810520	0.699		KCNK6	potassium channel, subfamily K, member 6
chr20_-_4229519	0.698	NM_000678	ADRA1D	adrenergic, alpha-1D-, receptor
chr13_+_45915479	0.697		LOC100190939	uncharacterized LOC100190939
chr6_-_6007632	0.695	NM_016588	NRN1	neuritin 1
chr5_-_1524022	0.690	NM_024830	LPCAT1	lysophosphatidylcholine acyltransferase 1
chr10_-_50122279	0.686	NM_001006939	LRRC18	leucine rich repeat containing 18
chr17_-_36904545	0.683	NM_007144	PCGF2	polycomb group ring finger 2
chr17_-_45928530	0.680		SP6	Sp6 transcription factor
chrX_+_153059903	0.680	NM_001204526 NM_006280	SSR4	signal sequence receptor, delta
chr17_-_56084571	0.680		SRSF1	serine/arginine-rich splicing factor 1
chr10_+_5406975	0.680	NM_053049	UCN3	urocortin 3 (stresscopin)
chr22_-_19166276	0.672		SLC25A1	solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
chr12_+_120907599	0.671	NM_001037494	DYNLL1	dynein, light chain, LC8-type 1
chrX_+_102611379	0.667	NM_001006612 NM_001006613 NM_001006614 NM_016303	WBP5	WW domain binding protein 5
chr3_+_50306305	0.666		SEMA3B	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
chr4_-_119757183	0.664		SEC24D	SEC24 family, member D (S. cerevisiae)
chr5_+_121647773	0.660	NM_001242935 NM_005460	SNCAIP	synuclein, alpha interacting protein
chr7_-_27170351	0.659	NM_002141	HOXA4	homeobox A4
chr11_+_68451978	0.652	NM_015973	GAL	galanin prepropeptide
chr10_-_128077072	0.647	NM_003474 NM_021641	ADAM12	ADAM metallopeptidase domain 12
chr12_+_120933916	0.646		DYNLL1	dynein, light chain, LC8-type 1
chr12_+_112451229	0.645
chr16_+_15737123	0.645	NM_001143979	NDE1	nudE nuclear distribution gene E homolog 1 (A. nidulans)
chr2_-_74692534	0.644	NM_001146158 NM_006302	MOGS	mannosyl-oligosaccharide glucosidase
chr17_+_31255170	0.636		TMEM98	transmembrane protein 98
chr17_-_56084514	0.636		SRSF1	serine/arginine-rich splicing factor 1
chr5_-_1523908	0.634		LPCAT1	lysophosphatidylcholine acyltransferase 1
chr11_-_114466471	0.634	NM_001077639 NM_017678	FAM55D	family with sequence similarity 55, member D
chr2_-_157189040	0.633	NM_006186	NR4A2	nuclear receptor subfamily 4, group A, member 2

Gene overrepresentation in process category:

Enrichment	P-value	GO Accession	GO Term
10.69	2.31e-06	GO:0001501	skeletal system development
6.43	9.80e-06	GO:0009790	embryo development
6.35	1.35e-04	GO:0009887	organ morphogenesis
5.17	1.45e-04	GO:0009888	tissue development
3.87	1.61e-04	GO:0009653	anatomical structure morphogenesis
9.28	2.22e-04	GO:0048729	tissue morphogenesis
10.72	3.49e-04	GO:0002009	morphogenesis of an epithelium
18.48	4.04e-04	GO:0030324	lung development
10.33	4.60e-04	GO:0003002	regionalization
2.51	4.69e-04	GO:0007275	multicellular organismal development
17.91	4.88e-04	GO:0030323	respiratory tube development
13.03	4.97e-04	GO:0009952	anterior/posterior pattern formation
8.17	6.45e-04	GO:0007389	pattern specification process
2.37	8.46e-04	GO:0032502	developmental process
3.23	1.10e-03	GO:0048513	organ development
11.53	1.13e-03	GO:0035239	tube morphogenesis
15.49	1.15e-03	GO:0060541	respiratory system development
7.57	1.21e-03	GO:0048598	embryonic morphogenesis
7.44	1.39e-03	GO:0060429	epithelium development
8.86	1.46e-03	GO:0035295	tube development
95.42	1.66e-03	GO:0060487	lung epithelial cell differentiation
13.76	2.29e-03	GO:0048705	skeletal system morphogenesis
85.88	2.36e-03	GO:0060479	lung cell differentiation
2.60	2.68e-03	GO:0048731	system development
18.13	3.92e-03	GO:0048706	embryonic skeletal system development
2.44	4.68e-03	GO:0048856	anatomical structure development
12.03	4.96e-03	GO:0060562	epithelial tube morphogenesis
66.07	5.59e-03	GO:0060428	lung epithelium development
57.26	8.85e-03	GO:0060441	epithelial tube branching involved in lung morphogenesis
15.08	9.67e-03	GO:0048754	branching morphogenesis of a tube
6.75	1.06e-02	GO:0043009	chordate embryonic development
6.67	1.16e-02	GO:0009792	embryo development ending in birth or egg hatching
14.19	1.30e-02	GO:0035107	appendage morphogenesis
14.19	1.30e-02	GO:0035108	limb morphogenesis
2.83	1.41e-02	GO:0030154	cell differentiation
7.75	1.51e-02	GO:0061061	muscle structure development
2.69	1.56e-02	GO:0051252	regulation of RNA metabolic process
13.65	1.57e-02	GO:0048736	appendage development
13.65	1.57e-02	GO:0060173	limb development
7.49	1.88e-02	GO:0001944	vasculature development
9.50	1.89e-02	GO:0048732	gland development
3.92	1.97e-02	GO:0006357	regulation of transcription from RNA polymerase II promoter
2.75	2.04e-02	GO:0048869	cellular developmental process
4.72	2.04e-02	GO:0010628	positive regulation of gene expression
42.95	2.19e-02	GO:0060425	lung morphogenesis
2.51	2.48e-02	GO:0010468	regulation of gene expression
11.75	3.22e-02	GO:0001763	morphogenesis of a branching structure
2.65	3.38e-02	GO:0006355	regulation of transcription, DNA-dependent
2.52	3.89e-02	GO:2000112	regulation of cellular macromolecule biosynthetic process
2.41	4.63e-02	GO:0019219	regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.41	4.63e-02	GO:0031326	regulation of cellular biosynthetic process

Gene overrepresentation in compartment category:

Enrichment	P-value	GO Accession	GO Term
6.36	2.72e-03	GO:0031012	extracellular matrix

Gene overrepresentation in function category:

Enrichment	P-value	GO Accession	GO Term
7.45	1.09e-03	GO:0016563	transcription activator activity
4.91	1.14e-03	GO:0043565	sequence-specific DNA binding
4.02	1.40e-03	GO:0001071	nucleic acid binding transcription factor activity
4.02	1.40e-03	GO:0003700	sequence-specific DNA binding transcription factor activity
3.93	1.82e-03	GO:0030528	transcription regulator activity
14.33	1.79e-02	GO:0005201	extracellular matrix structural constituent