Motif ID: ATF6.p2

Z-value: 1.359


Transcription factors associated with ATF6.p2:

Gene SymbolEntrez IDGene Name
ATF6 22926 activating transcription factor 6

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
ATF6hg19_v1_chr1_+_161736122_161736150-0.336.7e-02Click!


Activity profile for motif ATF6.p2.

activity profile for motif ATF6.p2


Sorted Z-values histogram for motif ATF6.p2

Sorted Z-values for motif ATF6.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ATF6.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr17_-_46688362 3.943 NM_004502
 HOXB7
homeobox B7
chr17_-_46688279 3.791 HOXB7
homeobox B7
chr7_-_73184535 3.248 NM_001306
 CLDN3
claudin 3
chr17_-_46687925 2.897 HOXB7
homeobox B7
chr19_+_16187266 2.556 TPM4
tropomyosin 4
chr14_-_38064440 2.502 NM_004496
 FOXA1
forkhead box A1
chr20_-_44420538 2.495 NM_080614
 WFDC3
WAP four-disulfide core domain 3
chr7_+_94024201 2.470 COL1A2
collagen, type I, alpha 2
chr19_+_16187315 2.465 TPM4
tropomyosin 4
chr19_+_16187306 2.238 TPM4
tropomyosin 4
chr7_-_27224762 2.138 NM_005523
 HOXA11
homeobox A11
chr8_-_95274540 2.074 NM_005261
NM_181702
 GEM

GTP binding protein overexpressed in skeletal muscle

chr2_+_176987412 2.050 NM_014213
 HOXD9
homeobox D9
chr7_-_37956377 2.015 SFRP4
secreted frizzled-related protein 4
chr3_+_100211554 2.005 TMEM45A
transmembrane protein 45A
chr7_-_37956515 1.958 NM_003014
 SFRP4
secreted frizzled-related protein 4
chr1_+_151483861 1.952 NM_020770
 CGN
cingulin
chr1_+_156030965 1.919 NM_020387
 RAB25
RAB25, member RAS oncogene family
chr6_+_151561094 1.903 NM_005100
 AKAP12
A kinase (PRKA) anchor protein 12
chr19_+_16187047 1.890 NM_003290
 TPM4
tropomyosin 4

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 51 entries
Enrichment   P-value GO Accession GO Term
95.42 1.66e-03 GO:0060487 lung epithelial cell differentiation
85.88 2.36e-03 GO:0060479 lung cell differentiation
66.07 5.59e-03 GO:0060428 lung epithelium development
57.26 8.85e-03 GO:0060441 epithelial tube branching involved in lung morphogenesis
42.95 2.19e-02 GO:0060425 lung morphogenesis
18.48 4.04e-04 GO:0030324 lung development
18.13 3.92e-03 GO:0048706 embryonic skeletal system development
17.91 4.88e-04 GO:0030323 respiratory tube development
15.49 1.15e-03 GO:0060541 respiratory system development
15.08 9.67e-03 GO:0048754 branching morphogenesis of a tube
14.19 1.30e-02 GO:0035107 appendage morphogenesis
14.19 1.30e-02 GO:0035108 limb morphogenesis
13.76 2.29e-03 GO:0048705 skeletal system morphogenesis
13.65 1.57e-02 GO:0048736 appendage development
13.65 1.57e-02 GO:0060173 limb development
13.03 4.97e-04 GO:0009952 anterior/posterior pattern formation
12.03 4.96e-03 GO:0060562 epithelial tube morphogenesis
11.75 3.22e-02 GO:0001763 morphogenesis of a branching structure
11.53 1.13e-03 GO:0035239 tube morphogenesis
10.72 3.49e-04 GO:0002009 morphogenesis of an epithelium

Gene overrepresentation in compartment category:

Showing 1 to 1 of 1 entries
Enrichment   P-value GO Accession GO Term
6.36 2.72e-03 GO:0031012 extracellular matrix

Gene overrepresentation in function category:

Showing 1 to 6 of 6 entries
Enrichment   P-value GO Accession GO Term
14.33 1.79e-02 GO:0005201 extracellular matrix structural constituent
7.45 1.09e-03 GO:0016563 transcription activator activity
4.91 1.14e-03 GO:0043565 sequence-specific DNA binding
4.02 1.40e-03 GO:0001071 nucleic acid binding transcription factor activity
4.02 1.40e-03 GO:0003700 sequence-specific DNA binding transcription factor activity
3.93 1.82e-03 GO:0030528 transcription regulator activity