Motif ID: AUGACAC

Z-value: 0.805


Mature miRNA associated with seed AUGACAC:

NamemiRBase Accession
hsa-miR-425 MIMAT0003393



Activity profile for motif AUGACAC.

activity profile for motif AUGACAC


Sorted Z-values histogram for motif AUGACAC

Sorted Z-values for motif AUGACAC



Network of associatons between targets according to the STRING database.



First level regulatory network of AUGACAC

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr19_-_55954229 2.951 NM_001145176
SHISA7
shisa homolog 7 (Xenopus laevis)
chr5_-_74162614 1.916 NM_015566
FAM169A
family with sequence similarity 169, member A
chr1_-_52456292 1.874 NM_002867
RAB3B
RAB3B, member RAS oncogene family
chr22_-_44708730 1.665 NM_001099294
KIAA1644
KIAA1644
chr7_+_45614081 1.622 NM_021116
ADCY1
adenylate cyclase 1 (brain)
chr20_+_10199455 1.553 NM_003081
NM_130811
SNAP25

synaptosomal-associated protein, 25kDa

chr11_+_33563772 1.534 NM_012194
C11orf41
chromosome 11 open reading frame 41
chr9_+_132934685 1.478 NM_014286
NCS1
neuronal calcium sensor 1
chr12_-_130388211 1.465 NM_133448
TMEM132D
transmembrane protein 132D
chr1_-_160039946 1.384 NM_002241
KCNJ10
potassium inwardly-rectifying channel, subfamily J, member 10
chr10_+_105036783 1.364 NM_032727
INA
internexin neuronal intermediate filament protein, alpha
chr9_+_132962871 1.338 NM_001128826
NCS1
neuronal calcium sensor 1
chr1_+_163038934 1.312 NM_001113381
RGS4
regulator of G-protein signaling 4
chr18_+_55019720 1.214 NM_015879
ST8SIA3
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
chr6_+_24126349 1.132 NM_080723
NRSN1
neurensin 1
chr4_+_2061238 1.120 NM_178557
NAT8L
N-acetyltransferase 8-like (GCN5-related, putative)
chr5_+_175223519 1.113 NM_006650
CPLX2
complexin 2
chr8_-_26371387 1.113 NM_007257
PNMA2
paraneoplastic antigen MA2
chr1_+_163038564 1.091 NM_005613
RGS4
regulator of G-protein signaling 4
chrX_+_51075082 1.076 NM_153183
NUDT10
nudix (nucleoside diphosphate linked moiety X)-type motif 10
chr13_+_37248048 1.008 NM_203451
SERTM1
serine-rich and transmembrane domain containing 1
chr14_-_77608132 1.006 NM_174976
ZDHHC22
zinc finger, DHHC-type containing 22
chr7_+_154862545 0.982 NM_024012
HTR5A
5-hydroxytryptamine (serotonin) receptor 5A
chr17_-_6459746 0.967 NM_001165966
NM_031220
PITPNM3

PITPNM family member 3

chr5_+_175298492 0.962 NM_001008220
CPLX2
complexin 2
chr17_+_41177247 0.948 NM_005440
RND2
Rho family GTPase 2
chr8_+_120220554 0.913 NM_052886
MAL2
mal, T-cell differentiation protein 2 (gene/pseudogene)
chr4_-_122686281 0.909 NM_152399
TMEM155
transmembrane protein 155
chr1_+_163041694 0.900 NM_001113380
RGS4
regulator of G-protein signaling 4
chr10_-_50970321 0.895 NM_001143996
NM_001143997
NM_018245
OGDHL


oxoglutarate dehydrogenase-like


chr22_+_26565424 0.892 NM_001184773
NM_001184774
NM_001184775
NM_001184776
NM_001184777
NM_021115
SEZ6L





seizure related 6 homolog (mouse)-like





chr1_+_163038395 0.873 NM_001102445
RGS4
regulator of G-protein signaling 4
chr18_+_67068134 0.863 NM_152721
DOK6
docking protein 6
chr5_+_140514787 0.843 NM_015669
PCDHB5
protocadherin beta 5
chr11_-_9025531 0.842 NM_020645
NRIP3
nuclear receptor interacting protein 3
chr11_+_109292837 0.809 NM_207645
C11orf87
chromosome 11 open reading frame 87
chr1_-_166944504 0.809 NM_199351
ILDR2
immunoglobulin-like domain containing receptor 2
chr9_-_117267710 0.793 NM_001173425
NM_015404
DFNB31

deafness, autosomal recessive 31

chr17_-_10741398 0.793 NM_001101387
PIRT
phosphoinositide-interacting regulator of transient receptor potential channels
chr11_+_7273141 0.790 NM_175733
SYT9
synaptotagmin IX
chr8_-_139509064 0.776 NM_015912
FAM135B
family with sequence similarity 135, member B
chr6_-_24645955 0.775 NM_001168375
NM_001168376
NM_001168374
NM_001168377
NM_014809
KIAA0319




KIAA0319




chr2_+_166326156 0.769 NM_001172173
CSRNP3
cysteine-serine-rich nuclear protein 3
chr5_+_143550395 0.768 NM_020768
KCTD16
potassium channel tetramerisation domain containing 16
chr11_-_133402227 0.753 NM_001012393
OPCML
opioid binding protein/cell adhesion molecule-like
chr19_-_46974789 0.751 NM_001103149
NM_018215
PNMAL1

PNMA-like 1

chr1_-_26232643 0.750 NM_203401
STMN1
stathmin 1
chr5_-_160975124 0.749 NM_000813
NM_021911
GABRB2

gamma-aminobutyric acid (GABA) A receptor, beta 2

chr5_-_138775213 0.744 NM_152686
DNAJC18
DnaJ (Hsp40) homolog, subfamily C, member 18
chr2_+_166428845 0.743 NM_024969
CSRNP3
cysteine-serine-rich nuclear protein 3
chr20_+_58251715 0.737 NM_001199506
PHACTR3
phosphatase and actin regulator 3
chr17_-_39890882 0.736 NM_001079870
NM_001079871
NM_177977
HAP1


huntingtin-associated protein 1


chr14_+_64932216 0.728 NM_004857
AKAP5
A kinase (PRKA) anchor protein 5
chr13_-_95364248 0.726 NM_007084
SOX21
SRY (sex determining region Y)-box 21
chr16_+_8768403 0.723 NM_020686
ABAT
4-aminobutyrate aminotransferase
chr11_-_132812870 0.706 NM_002545
OPCML
opioid binding protein/cell adhesion molecule-like
chr6_+_96463844 0.702 NM_006581
FUT9
fucosyltransferase 9 (alpha (1,3) fucosyltransferase)
chrX_-_6146655 0.692 NM_181332
NLGN4X
neuroligin 4, X-linked
chr1_+_154540250 0.691 NM_000748
CHRNB2
cholinergic receptor, nicotinic, beta 2 (neuronal)
chr20_-_31239558 0.687 NM_182584
C20orf203
chromosome 20 open reading frame 203
chr20_+_58179601 0.684 NM_080672
PHACTR3
phosphatase and actin regulator 3
chr3_+_159943252 0.683 NM_001168214
C3orf80
chromosome 3 open reading frame 80
chr20_+_58296264 0.671 NM_183244
NM_183246
PHACTR3

phosphatase and actin regulator 3

chr20_+_58152563 0.662 NM_001199505
PHACTR3
phosphatase and actin regulator 3
chr12_+_108523464 0.654 NM_014653
WSCD2
WSC domain containing 2
chr15_+_52043738 0.653 NM_001142885
NM_014548
TMOD2

tropomodulin 2 (neuronal)

chr20_-_41818464 0.649 NM_007050
NM_133170
PTPRT

protein tyrosine phosphatase, receptor type, T

chr12_-_10324675 0.648 NM_001172632
NM_001172633
NM_002543
OLR1


oxidized low density lipoprotein (lectin-like) receptor 1


chr4_+_88754120 0.648 NM_001184695
NM_001184696
NM_001184697
NM_020203
MEPE



matrix extracellular phosphoglycoprotein



chrX_-_152939764 0.636 NM_001039582
PNCK
pregnancy up-regulated non-ubiquitously expressed CaM kinase
chr3_+_39851028 0.633 NM_015460
MYRIP
myosin VIIA and Rab interacting protein
chrX_+_113818550 0.633 NM_000868
HTR2C
5-hydroxytryptamine (serotonin) receptor 2C
chrX_+_37865834 0.632 NM_001163335
NM_138780
SYTL5

synaptotagmin-like 5

chr17_+_76227390 0.626 NM_001204210
NM_001204211
NM_001204212
TMEM235


transmembrane protein 235


chr4_-_90759446 0.625 NM_001146055
SNCA
synuclein, alpha (non A4 component of amyloid precursor)
chr4_+_118955499 0.622 NM_004784
NDST3
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3
chr20_-_43438881 0.619 NM_001205317
NM_182970
RIMS4

regulating synaptic membrane exocytosis 4

chr2_+_11674241 0.607 NM_014668
GREB1
growth regulation by estrogen in breast cancer 1
chrX_-_6145887 0.594 NM_020742
NLGN4X
neuroligin 4, X-linked
chr10_-_133109983 0.594 NM_174937
TCERG1L
transcription elongation regulator 1-like
chr11_+_24518515 0.585 NM_001009909
NM_001252008
NM_001252010
LUZP2


leucine zipper protein 2


chr4_-_170947428 0.585 NM_021647
MFAP3L
microfibrillar-associated protein 3-like
chr19_-_44324767 0.579 NM_182573
LYPD5
LY6/PLAUR domain containing 5
chr16_+_23765947 0.577 NM_022097
CHP2
calcineurin B homologous protein 2
chr7_+_87257704 0.576 NM_001134405
NM_001134406
NM_138290
RUNDC3B


RUN domain containing 3B


chr1_-_226076766 0.574 NM_020997
LEFTY1
left-right determination factor 1
chr6_+_72922513 0.573 NM_001168407
NM_001168408
RIMS1

regulating synaptic membrane exocytosis 1

chr11_-_12030882 0.570 NM_013253
DKK3
dickkopf 3 homolog (Xenopus laevis)
chr1_-_26233367 0.568 NM_203399
STMN1
stathmin 1
chr1_+_39957298 0.555 NM_181809
BMP8A
bone morphogenetic protein 8a
chr17_+_70117154 0.554 NM_000346
SOX9
SRY (sex determining region Y)-box 9
chr11_-_12030622 0.553 NM_015881
DKK3
dickkopf 3 homolog (Xenopus laevis)
chr3_-_160822625 0.550 NM_033169
NM_001038628
NM_003781
NM_033167
NM_033168
B3GALNT1




beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)




chr9_-_117265452 0.545 NM_001083885
DFNB31
deafness, autosomal recessive 31
chr1_-_196577438 0.531 NM_198503
KCNT2
potassium channel, subfamily T, member 2
chr12_-_48119224 0.528 NM_001172439
NM_001172440
NM_006025
ENDOU


endonuclease, polyU-specific


chr5_-_83680590 0.527 NM_005711
EDIL3
EGF-like repeats and discoidin I-like domains 3
chr5_-_34043234 0.527 NM_030945
NM_181435
C1QTNF3

C1q and tumor necrosis factor related protein 3

chr20_-_6104056 0.522 NM_017671
FERMT1
fermitin family member 1
chr22_-_39240016 0.518 NM_014293
NPTXR
neuronal pentraxin receptor
chrX_+_38420690 0.517 NM_004615
TSPAN7
tetraspanin 7
chr8_+_104152876 0.515 NM_001024372
NM_024812
BAALC

brain and acute leukemia, cytoplasmic

chr3_+_178276487 0.515 NM_005832
KCNMB2
potassium large conductance calcium-activated channel, subfamily M, beta member 2
chr16_+_8814567 0.514 NM_001127448
ABAT
4-aminobutyrate aminotransferase
chr14_-_88737160 0.506 NM_138318
KCNK10
potassium channel, subfamily K, member 10
chr11_-_12030128 0.503 NM_001018057
DKK3
dickkopf 3 homolog (Xenopus laevis)
chr1_+_226736500 0.501 NM_001003665
C1orf95
chromosome 1 open reading frame 95
chr4_-_156298094 0.500 NM_001039580
MAP9
microtubule-associated protein 9
chr20_-_36889173 0.493 NM_001029864
KIAA1755
KIAA1755
chr22_+_35937351 0.488 NM_014310
RASD2
RASD family, member 2
chr7_+_79764087 0.486 NM_002069
GNAI1
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
chr11_-_6502563 0.486 NM_001242854
NM_001242855
NM_001242856
NM_012402
ARFIP2



ADP-ribosylation factor interacting protein 2



chr4_-_17513676 0.480 NM_000320
QDPR
quinoid dihydropteridine reductase
chr11_-_74109417 0.470 NM_173582
PGM2L1
phosphoglucomutase 2-like 1
chr8_+_91803777 0.469 NM_022351
NECAB1
N-terminal EF-hand calcium binding protein 1
chr7_+_128828712 0.466 NM_005631
SMO
smoothened, frizzled family receptor
chr19_-_44306525 0.464 NM_001031749
LYPD5
LY6/PLAUR domain containing 5
chr4_-_90758126 0.461 NM_001146054
NM_007308
NM_000345
SNCA


synuclein, alpha (non A4 component of amyloid precursor)


chr14_-_94254765 0.455 NM_178013
PRIMA1
proline rich membrane anchor 1
chr12_+_1929432 0.455 NM_001039029
NM_001163925
NM_001163926
LRTM2


leucine-rich repeats and transmembrane domains 2


chr1_-_184006828 0.452 NM_015101
GLT25D2
glycosyltransferase 25 domain containing 2
chr14_-_88789531 0.451 NM_138317
KCNK10
potassium channel, subfamily K, member 10
chr12_-_104234968 0.448 NM_001031701
NT5DC3
5'-nucleotidase domain containing 3
chr11_-_123525300 0.447 NM_001040151
NM_018400
SCN3B

sodium channel, voltage-gated, type III, beta

chr8_-_33330630 0.446 NM_032664
FUT10
fucosyltransferase 10 (alpha (1,3) fucosyltransferase)
chr20_+_8112762 0.444 NM_015192
NM_182734
PLCB1

phospholipase C, beta 1 (phosphoinositide-specific)

chr15_+_69606741 0.441 NM_001104554
PAQR5
progestin and adipoQ receptor family member V
chr2_-_73496595 0.433 NM_001080410
FBXO41
F-box protein 41
chr12_+_72666462 0.427 NM_013381
TRHDE
thyrotropin-releasing hormone degrading enzyme
chr15_+_69591272 0.421 NM_017705
PAQR5
progestin and adipoQ receptor family member V
chr16_+_18995255 0.421 NM_024847
TMC7
transmembrane channel-like 7
chr1_-_241803203 0.419 NM_014322
OPN3
opsin 3
chr16_+_8806825 0.419 NM_000663
ABAT
4-aminobutyrate aminotransferase
chr4_-_96470350 0.416 NM_003728
UNC5C
unc-5 homolog C (C. elegans)
chr4_+_88742549 0.413 NM_001184694
MEPE
matrix extracellular phosphoglycoprotein
chr18_-_47721165 0.409 NM_001080467
MYO5B
myosin VB
chr12_+_57828457 0.405 NM_005538
INHBC
inhibin, beta C
chr4_-_170924911 0.403 NM_001009554
MFAP3L
microfibrillar-associated protein 3-like
chrX_-_152938742 0.403 NM_001135740
PNCK
pregnancy up-regulated non-ubiquitously expressed CaM kinase
chr18_+_52495618 0.402 NM_004163
RAB27B
RAB27B, member RAS oncogene family
chr18_+_55102777 0.397 NM_004852
ONECUT2
one cut homeobox 2
chr13_-_46425756 0.394 NM_198849
SIAH3
seven in absentia homolog 3 (Drosophila)
chr3_+_178254223 0.393 NM_181361
KCNMB2
potassium large conductance calcium-activated channel, subfamily M, beta member 2
chr14_-_88793250 0.392 NM_021161
KCNK10
potassium channel, subfamily K, member 10
chr11_-_26593667 0.387 NM_001135091
NM_001135092
NM_145650
MUC15


mucin 15, cell surface associated


chr16_+_85061303 0.386 NM_014732
KIAA0513
KIAA0513
chr5_+_68800003 0.383 NM_001205255
OCLN
occludin
chr1_-_22469414 0.377 NM_030761
WNT4
wingless-type MMTV integration site family, member 4
chr8_+_75736771 0.377 NM_015886
PI15
peptidase inhibitor 15
chr6_+_73076431 0.373 NM_001168411
RIMS1
regulating synaptic membrane exocytosis 1
chr4_-_7044664 0.373 NM_153376
CCDC96
coiled-coil domain containing 96
chrX_-_10851808 0.369 NM_033290
MID1
midline 1 (Opitz/BBB syndrome)
chr8_-_143695812 0.367 NM_015193
ARC
activity-regulated cytoskeleton-associated protein
chr5_+_178368193 0.364 NM_001178089
NM_001178090
NM_182594
ZNF454


zinc finger protein 454


chr13_+_46039024 0.363 NM_031431
COG3
component of oligomeric golgi complex 3
chr17_-_27332888 0.362 NM_001098635
NM_178860
SEZ6

seizure related 6 homolog (mouse)

chr6_+_72926462 0.360 NM_001168410
RIMS1
regulating synaptic membrane exocytosis 1
chr5_+_156696351 0.359 NM_014376
CYFIP2
cytoplasmic FMR1 interacting protein 2
chr14_-_93651242 0.359 NM_022151
MOAP1
modulator of apoptosis 1
chr10_-_129691202 0.359 NM_152311
CLRN3
clarin 3
chr5_+_156693051 0.359 NM_001037333
NM_001037332
CYFIP2

cytoplasmic FMR1 interacting protein 2

chr15_+_51633712 0.359 NM_181789
GLDN
gliomedin
chr16_+_18995508 0.356 NM_001160364
TMC7
transmembrane channel-like 7
chr1_+_154966061 0.356 NM_018655
LENEP
lens epithelial protein
chr1_+_28099682 0.355 NM_177424
STX12
syntaxin 12
chr15_-_52483564 0.354 NM_016194
GNB5
guanine nucleotide binding protein (G protein), beta 5
chr19_+_11976843 0.354 NM_152262
ZNF439
zinc finger protein 439
chr3_-_178789597 0.353 NM_022470
NM_152240
ZMAT3

zinc finger, matrin-type 3

chr18_-_29264394 0.353 NM_004775
B4GALT6
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6
chr8_+_63161499 0.348 NM_173688
NKAIN3
Na+/K+ transporting ATPase interacting 3
chr17_-_61523544 0.347 NM_001017916
NM_001915
CYB561

cytochrome b-561

chr11_+_121322848 0.347 NM_003105
SORL1
sortilin-related receptor, L(DLR class) A repeats containing
chr1_+_2518071 0.345 NM_001195736
NM_001195737
NM_001195738
NM_001195740
NM_001195741
NM_152371
FAM213B





family with sequence similarity 213, member B





chr4_+_37585854 0.342 NM_018302
C4orf19
chromosome 4 open reading frame 19
chr6_-_41006927 0.340 NM_173561
UNC5CL
unc-5 homolog C (C. elegans)-like
chr20_-_4990913 0.339 NM_203327
SLC23A2
solute carrier family 23 (nucleobase transporters), member 2
chr13_+_51796363 0.338 NM_001242312
NM_145019
FAM124A

family with sequence similarity 124A

chr4_-_53525316 0.336 NM_022832
USP46
ubiquitin specific peptidase 46
chr1_+_25943958 0.336 NM_020379
MAN1C1
mannosidase, alpha, class 1C, member 1
chr9_+_133884503 0.335 NM_006059
LAMC3
laminin, gamma 3
chr17_+_53342320 0.333 NM_002126
HLF
hepatic leukemia factor
chr6_+_158402887 0.333 NM_003898
SYNJ2
synaptojanin 2
chr13_+_24734788 0.332 NM_001166271
NM_153023
SPATA13

spermatogenesis associated 13

chr6_+_72926144 0.332 NM_001168409
RIMS1
regulating synaptic membrane exocytosis 1
chr17_+_43861628 0.332 NM_001145146
NM_001145147
NM_001145148
NM_004382
CRHR1



corticotropin releasing hormone receptor 1



chr15_-_52472075 0.328 NM_006578
GNB5
guanine nucleotide binding protein (G protein), beta 5
chr13_-_37494370 0.326 NM_001127217
NM_005905
SMAD9

SMAD family member 9

chr4_+_37455551 0.321 NM_001104629
C4orf19
chromosome 4 open reading frame 19
chr6_+_157802479 0.320 NM_024630
NM_153746
ZDHHC14

zinc finger, DHHC-type containing 14

chr20_-_4982133 0.319 NM_005116
SLC23A2
solute carrier family 23 (nucleobase transporters), member 2
chr11_-_8832881 0.319 NM_139157
ST5
suppression of tumorigenicity 5
chr2_+_54952148 0.317 NM_001039753
EML6
echinoderm microtubule associated protein like 6
chr7_-_138665853 0.317 NM_001164665
NM_020910
KIAA1549

KIAA1549

chr5_-_148442606 0.317 NM_024577
SH3TC2
SH3 domain and tetratricopeptide repeats 2
chr15_+_32322690 0.311 NM_000746
NM_001190455
CHRNA7

cholinergic receptor, nicotinic, alpha 7

chr11_+_13690151 0.306 NM_032228
FAR1
fatty acyl CoA reductase 1
chr13_-_30169795 0.300 NM_003045
SLC7A1
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chr15_-_56035176 0.299 NM_173814
PRTG
protogenin
chr8_-_88886224 0.298 NM_152418
DCAF4L2
DDB1 and CUL4 associated factor 4-like 2
chr2_+_26568900 0.298 NM_033505
EPT1
ethanolaminephosphotransferase 1 (CDP-ethanolamine-specific)

Gene Ontology Analysis

Nothing significant found in process category.

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
2.04 6.48e-03 GO:0016020 membrane
98.81 8.51e-03 GO:0031201 SNARE complex
9.85 2.62e-02 GO:0043005 neuron projection
9.73 2.75e-02 GO:0045202 synapse
2.13 3.03e-02 GO:0044425 membrane part

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
170.63 2.12e-03 GO:0017075 syntaxin-1 binding
69.55 1.34e-02 GO:0019905 syntaxin binding
58.69 1.88e-02 GO:0000149 SNARE binding