Motif ID: BACH2.p2

Z-value: 1.229


Transcription factors associated with BACH2.p2:

Gene SymbolEntrez IDGene Name
BACH2 60468 BTB and CNC homology 1, basic leucine zipper transcription factor 2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
BACH2hg19_v1_chr6_-_91006580_910066440.281.2e-01Click!


Activity profile for motif BACH2.p2.

activity profile for motif BACH2.p2


Sorted Z-values histogram for motif BACH2.p2

Sorted Z-values for motif BACH2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of BACH2.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_+_17634689 3.921 NM_012387
PADI4
peptidyl arginine deiminase, type IV
chr19_+_38794800 3.404 NM_033520
C19orf33
chromosome 19 open reading frame 33
chr6_-_24877453 3.274 NM_015864
FAM65B
family with sequence similarity 65, member B
chr14_-_94855120 3.225 NM_000295
SERPINA1
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chr1_+_154377847 3.174 IL6R
interleukin 6 receptor
chr14_-_25103365 3.074 NM_004131
GZMB
granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
chr1_-_162381805 3.020 NM_053282
SH2D1B
SH2 domain containing 1B
chr1_+_154378044 2.729 IL6R
interleukin 6 receptor
chr16_+_31366519 2.682 ITGAX
integrin, alpha X (complement component 3 receptor 4 subunit)
chr21_+_30517897 2.656 C21orf7
chromosome 21 open reading frame 7
chr5_-_90610218 2.639 LOC100505994
uncharacterized LOC100505994
chr1_+_154377668 2.637 NM_000565
NM_001206866
NM_181359
IL6R


interleukin 6 receptor


chr5_+_35856990 2.548 NM_002185
IL7R
interleukin 7 receptor
chr4_+_74606222 2.435 NM_000584
IL8
interleukin 8
chr6_+_106959729 2.389 NM_001624
AIM1
absent in melanoma 1
chr1_+_223889253 2.353 NM_001146068
CAPN2
calpain 2, (m/II) large subunit
chr14_-_94854910 2.118 SERPINA1
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chr3_-_187454247 2.107 NM_001130845
BCL6
B-cell CLL/lymphoma 6
chr16_+_30076993 2.088 NM_001243177
NM_184041
ALDOA

aldolase A, fructose-bisphosphate

chr22_+_23134980 2.012


chr12_-_8219001 1.973 C3AR1
complement component 3a receptor 1
chr22_+_23165273 1.950


chr9_-_107665959 1.940 ABCA1
ATP-binding cassette, sub-family A (ABC1), member 1
chrY_+_15016775 1.937 DDX3Y
DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked
chr19_-_44174497 1.937 NM_001005376
NM_001005377
NM_002659
PLAUR


plasminogen activator, urokinase receptor


chr1_-_84972259 1.931 NM_005274
GNG5
guanine nucleotide binding protein (G protein), gamma 5
chr15_+_89182038 1.927 NM_002201
ISG20
interferon stimulated exonuclease gene 20kDa
chr12_-_8218930 1.908 NM_004054
C3AR1
complement component 3a receptor 1
chr16_+_30077120 1.906 ALDOA
aldolase A, fructose-bisphosphate
chr6_+_44195008 1.899 SLC29A1
solute carrier family 29 (nucleoside transporters), member 1
chr16_+_30077146 1.856 ALDOA
aldolase A, fructose-bisphosphate
chrX_-_129244422 1.826 ELF4
E74-like factor 4 (ets domain transcription factor)
chr7_-_95225802 1.815 NM_002612
PDK4
pyruvate dehydrogenase kinase, isozyme 4
chr1_+_26606586 1.803 SH3BGRL3
SH3 domain binding glutamic acid-rich protein like 3
chr11_-_118134986 1.797 MPZL2
myelin protein zero-like 2
chr10_-_31288420 1.776 NM_001143769
ZNF438
zinc finger protein 438
chr20_+_44637539 1.767 NM_004994
MMP9
matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
chr22_+_23040394 1.761 IGL@
immunoglobulin lambda locus
chr3_-_71834187 1.755 NM_001126128
NM_021935
PROK2

prokineticin 2

chrX_-_129244471 1.744 NM_001421
ELF4
E74-like factor 4 (ets domain transcription factor)
chr1_-_152009406 1.717 S100A11
S100 calcium binding protein A11
chr11_+_2924504 1.715 SLC22A18
solute carrier family 22, member 18
chr12_-_10875848 1.713 NM_001145426
NM_003651
CSDA

cold shock domain protein A

chr11_-_118134868 1.711


chr5_+_179247841 1.694 NM_003900
SQSTM1
sequestosome 1
chr17_-_18162018 1.689 FLII
flightless I homolog (Drosophila)
chr5_+_179247903 1.687 SQSTM1
sequestosome 1
chr21_+_30452872 1.683 NM_020152
C21orf7
chromosome 21 open reading frame 7
chr16_+_31366529 1.663 ITGAX
integrin, alpha X (complement component 3 receptor 4 subunit)
chr11_-_118134956 1.653 MPZL2
myelin protein zero-like 2
chr19_-_44174271 1.648 PLAUR
plasminogen activator, urokinase receptor
chr16_+_56642477 1.647 NM_005953
MT2A
metallothionein 2A
chr6_+_29910308 1.645 HLA-A
major histocompatibility complex, class I, A
chr6_+_33043702 1.645 NM_002121
HLA-DPB1
major histocompatibility complex, class II, DP beta 1
chr3_+_154797644 1.643 NM_007287
MME
membrane metallo-endopeptidase
chr20_-_52199635 1.637 NM_006526
ZNF217
zinc finger protein 217
chr1_+_36621457 1.631 MAP7D1
MAP7 domain containing 1
chr1_-_152009440 1.610 S100A11
S100 calcium binding protein A11
chr2_+_113875469 1.605 NM_000577
NM_173841
NM_173843
IL1RN


interleukin 1 receptor antagonist


chr17_-_42345434 1.605 NM_000342
SLC4A1
solute carrier family 4, anion exchanger, member 1 (erythrocyte membrane protein band 3, Diego blood group)
chr11_-_118135197 1.581 NM_005797
NM_144765
MPZL2

myelin protein zero-like 2

chr22_-_37545944 1.578 NM_000878
IL2RB
interleukin 2 receptor, beta
chr1_-_84971848 1.577 GNG5
guanine nucleotide binding protein (G protein), gamma 5
chr7_+_143078395 1.571 ZYX
zyxin
chr1_-_6662681 1.566 KLHL21
kelch-like 21 (Drosophila)
chr1_-_152009490 1.566 NM_005620
S100A11
S100 calcium binding protein A11
chrY_+_15016698 1.565 NM_004660
DDX3Y
DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked
chr1_-_89591685 1.564 NM_004120
GBP2
guanylate binding protein 2, interferon-inducible
chr2_+_169926084 1.561 DHRS9
dehydrogenase/reductase (SDR family) member 9
chr17_+_21188021 1.554 MAP2K3
mitogen-activated protein kinase kinase 3
chr1_-_6662898 1.551 NM_014851
KLHL21
kelch-like 21 (Drosophila)
chr5_+_179247911 1.547 SQSTM1
sequestosome 1
chr21_+_30671113 1.519 BACH1
BTB and CNC homology 1, basic leucine zipper transcription factor 1
chr10_+_104155431 1.517 NM_002502
NFKB2
nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
chr7_+_143078358 1.502 NM_001010972
NM_003461
ZYX

zyxin

chr13_-_41593405 1.502 ELF1
E74-like factor 1 (ets domain transcription factor)
chr11_+_67351065 1.502 NM_000852
GSTP1
glutathione S-transferase pi 1
chr7_+_143078457 1.498 ZYX
zyxin
chr17_-_18161869 1.493 FLII
flightless I homolog (Drosophila)
chr12_-_15114495 1.482 NM_001175
ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
chr1_+_36621751 1.479 NM_018067
MAP7D1
MAP7 domain containing 1
chr1_-_108231122 1.478 NM_001079874
VAV3
vav 3 guanine nucleotide exchange factor
chr11_+_10476665 1.467 NM_001025389
AMPD3
adenosine monophosphate deaminase 3
chr7_-_158611301 1.464 ESYT2
extended synaptotagmin-like protein 2
chr10_+_17270257 1.460 NM_003380
VIM
vimentin
chr12_+_122614486 1.459 MLXIP
MLX interacting protein
chr19_+_49376488 1.451 PPP1R15A
protein phosphatase 1, regulatory subunit 15A
chr1_+_26606621 1.450 SH3BGRL3
SH3 domain binding glutamic acid-rich protein like 3
chr10_-_6019454 1.444 NM_002189
NM_172200
IL15RA

interleukin 15 receptor, alpha

chr2_+_113763448 1.433 NM_014440
IL36A
interleukin 36, alpha
chr2_-_85641128 1.430 CAPG
capping protein (actin filament), gelsolin-like
chr9_-_107666046 1.430 ABCA1
ATP-binding cassette, sub-family A (ABC1), member 1
chr22_+_23063107 1.428 IGLJ3
immunoglobulin lambda joining 3
chr16_+_29789560 1.423 NM_152338
ZG16
zymogen granule protein 16 homolog (rat)
chr16_+_57662301 1.403 NM_001145771
NM_001145772
NM_001145773
NM_201524
NM_201525
GPR56




G protein-coupled receptor 56




chr7_+_143078399 1.382 ZYX
zyxin
chr10_+_17270469 1.374 VIM
vimentin
chr18_+_55297533 1.370 NM_001242804
LOC100505549
uncharacterized LOC100505549
chr17_+_21187967 1.369 NM_145109
MAP2K3
mitogen-activated protein kinase kinase 3
chr17_-_38721701 1.367 NM_001838
CCR7
chemokine (C-C motif) receptor 7
chr1_+_174844655 1.362 NM_001035230
RABGAP1L
RAB GTPase activating protein 1-like
chr19_-_52255099 1.357 NM_001193306
NM_002029
FPR1

formyl peptide receptor 1

chr21_+_30671227 1.351 BACH1
BTB and CNC homology 1, basic leucine zipper transcription factor 1
chr2_+_89185055 1.348


chr2_+_201997687 1.328 NM_001202518
CFLAR
CASP8 and FADD-like apoptosis regulator
chr14_+_22989334 1.321


chr19_+_36630999 1.320 CAPNS1
calpain, small subunit 1
chr6_-_41673677 1.305 TFEB
transcription factor EB
chr7_+_143058794 1.302 ZYX
zyxin
chr7_+_143078447 1.301 ZYX
zyxin
chr7_+_1577118 1.300 MAFK
v-maf musculoaponeurotic fibrosarcoma oncogene homolog K (avian)
chr1_+_223900226 1.299 CAPN2
calpain 2, (m/II) large subunit
chr17_+_75372164 1.298 NM_001113494
SEPT9
septin 9
chr22_-_39151457 1.292 NM_001199580
SUN2
Sad1 and UNC84 domain containing 2
chr21_+_30671217 1.285 NM_001186
BACH1
BTB and CNC homology 1, basic leucine zipper transcription factor 1
chr7_+_143078444 1.284 ZYX
zyxin
chr14_-_94849552 1.278 SERPINA1
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chr1_-_28520379 1.272 NM_001164721
NM_001164722
PTAFR

platelet-activating factor receptor

chr16_-_18798077 1.269


chr14_-_24777064 1.264


chr1_-_84971882 1.259 GNG5
guanine nucleotide binding protein (G protein), gamma 5
chrX_-_129244652 1.256 NM_001127197
ELF4
E74-like factor 4 (ets domain transcription factor)
chr12_-_39299335 1.251 NM_153634
CPNE8
copine VIII
chr19_+_36631001 1.250 CAPNS1
calpain, small subunit 1
chr2_+_87755059 1.231 LINC00152
long intergenic non-protein coding RNA 152
chr22_+_22723972 1.230


chr19_+_36630846 1.223 NM_001003962
NM_001749
CAPNS1

calpain, small subunit 1

chr1_+_223900061 1.223 NM_001748
CAPN2
calpain 2, (m/II) large subunit
chr17_+_80193649 1.215 NM_001206952
SLC16A3
solute carrier family 16, member 3 (monocarboxylic acid transporter 4)
chr8_-_133772808 1.211 NM_001145153
NM_144649
TMEM71

transmembrane protein 71

chrX_+_12993224 1.209 NM_021109
TMSB4X
thymosin beta 4, X-linked
chr3_+_160394946 1.205 NM_025047
ARL14
ADP-ribosylation factor-like 14
chr21_-_36421195 1.202 RUNX1
runt-related transcription factor 1
chr18_+_61637262 1.202 NM_001031848
NM_002640
NM_198833
SERPINB8


serpin peptidase inhibitor, clade B (ovalbumin), member 8


chr6_-_31704318 1.202 NM_001288
CLIC1
chloride intracellular channel 1
chr10_-_121602030 1.201 MCMBP
minichromosome maintenance complex binding protein
chr17_+_21188032 1.195 MAP2K3
mitogen-activated protein kinase kinase 3
chr15_-_80263460 1.192 NM_001114735
NM_004049
BCL2A1

BCL2-related protein A1

chr11_-_65430427 1.191 NM_001145138
NM_001243984
NM_001243985
NM_021975
RELA



v-rel reticuloendotheliosis viral oncogene homolog A (avian)



chr8_-_11710921 1.182


chr1_-_153935190 1.176 SLC39A1
solute carrier family 39 (zinc transporter), member 1
chr6_-_31704070 1.164 CLIC1
chloride intracellular channel 1
chr7_-_33080517 1.156 NM_001166118
NM_016489
NT5C3

5'-nucleotidase, cytosolic III

chr18_-_74207145 1.153 NM_014643
ZNF516
zinc finger protein 516
chr13_+_53602829 1.145 NM_006418
OLFM4
olfactomedin 4
chr10_-_73611050 1.143 NM_001042465
NM_001042466
NM_002778
PSAP


prosaposin


chr16_+_1290677 1.133 NM_003294
TPSB2
TPSAB1
tryptase beta 2 (gene/pseudogene)
tryptase alpha/beta 1
chr10_-_73611005 1.133 PSAP
prosaposin
chr16_-_12010518 1.131 NM_001130007
GSPT1
G1 to S phase transition 1
chr3_-_71774407 1.128 NM_001134651
EIF4E3
eukaryotic translation initiation factor 4E family member 3
chr17_-_18162042 1.126 NM_002018
FLII
flightless I homolog (Drosophila)
chrX_-_154563735 1.125 NM_001289
CLIC2
chloride intracellular channel 2
chr5_-_141061798 1.118 NM_022481
ARAP3
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
chr4_-_74088773 1.112 ANKRD17
ankyrin repeat domain 17
chr22_+_22676814 1.108


chr22_+_39378404 1.107 NM_004900
APOBEC3D
APOBEC3B
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3D
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B
chr14_-_23426356 1.099 HAUS4
HAUS augmin-like complex, subunit 4
chr22_-_39151979 1.099 SUN2
Sad1 and UNC84 domain containing 2
chr16_-_1280162 1.098 NM_024164
TPSB2
TPSAB1
tryptase beta 2 (gene/pseudogene)
tryptase alpha/beta 1
chr17_-_43502992 1.090 NM_199282
ARHGAP27
Rho GTPase activating protein 27
chr6_-_31704093 1.086 CLIC1
chloride intracellular channel 1
chr7_-_7758237 1.083 NM_002947
RPA3
replication protein A3, 14kDa
chr2_+_48541767 1.083 NM_002158
FOXN2
forkhead box N2
chr5_-_141061749 1.080 ARAP3
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
chr14_-_23426265 1.077 NM_001166269
NM_001166270
NM_017815
HAUS4


HAUS augmin-like complex, subunit 4


chr2_+_87754991 1.073 LINC00152
long intergenic non-protein coding RNA 152
chr11_-_66103874 1.065 NM_004292
RIN1
Ras and Rab interactor 1
chr1_+_17866276 1.060 NM_018125
ARHGEF10L
Rho guanine nucleotide exchange factor (GEF) 10-like
chr6_+_64231626 1.050 PTP4A1
protein tyrosine phosphatase type IVA, member 1
chr8_-_59572247 1.049 NSMAF
neutral sphingomyelinase (N-SMase) activation associated factor
chr7_+_150065330 1.041 REPIN1
replication initiator 1
chr13_-_41593491 1.041 NM_172373
ELF1
E74-like factor 1 (ets domain transcription factor)
chr16_+_28505920 1.037 NM_018690
APOBR
apolipoprotein B receptor
chr17_-_7590731 1.036 NM_000546
NM_001126112
NM_001126113
NM_001126114
TP53



tumor protein p53



chr1_-_225616556 1.028 NM_194442
LBR
lamin B receptor
chr6_-_31704304 1.023 CLIC1
chloride intracellular channel 1
chr5_+_73981055 1.020 HEXB
hexosaminidase B (beta polypeptide)
chr10_-_73611041 1.015 PSAP
prosaposin
chr21_-_36421461 1.007 RUNX1
runt-related transcription factor 1
chr22_+_20861964 1.002 MED15
mediator complex subunit 15
chr19_-_3969734 0.993 NM_001348
DAPK3
death-associated protein kinase 3
chr6_-_111927473 0.991 NM_001164281
NM_147686
TRAF3IP2

TRAF3 interacting protein 2

chr7_+_150434679 0.989 GIMAP5
GTPase, IMAP family member 5
chr2_+_28615771 0.987 NM_005253
FOSL2
FOS-like antigen 2
chr16_+_31404596 0.968 NM_005353
ITGAD
integrin, alpha D
chr3_+_184038050 0.960 NM_004953
EIF4G1
eukaryotic translation initiation factor 4 gamma, 1
chr5_+_40841296 0.959 NM_032587
CARD6
caspase recruitment domain family, member 6
chr22_-_39152008 0.959 NM_001199579
NM_015374
SUN2

Sad1 and UNC84 domain containing 2

chr17_+_75085234 0.955 NM_001204410
SEC14L1
LINC00338
SEC14-like 1 (S. cerevisiae)
long intergenic non-protein coding RNA 338
chr1_+_223900328 0.955 CAPN2
calpain 2, (m/II) large subunit
chr19_+_10959105 0.954 NM_001136482
C19orf38
chromosome 19 open reading frame 38
chr6_-_31704281 0.953 CLIC1
chloride intracellular channel 1
chr8_-_59571920 0.949 NM_001144772
NSMAF
neutral sphingomyelinase (N-SMase) activation associated factor
chr15_+_89631380 0.945 NM_007011
NM_152924
ABHD2

abhydrolase domain containing 2

chr13_+_28196004 0.944 POLR1D
polymerase (RNA) I polypeptide D, 16kDa
chr10_-_73610958 0.942 PSAP
prosaposin
chr8_-_59572385 0.941 NSMAF
neutral sphingomyelinase (N-SMase) activation associated factor
chr1_-_1149495 0.939 NM_003327
TNFRSF4
tumor necrosis factor receptor superfamily, member 4
chr22_+_20861886 0.936 MED15
mediator complex subunit 15
chr3_-_12800739 0.936 NM_018306
TMEM40
transmembrane protein 40

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
3.27 2.43e-04 GO:0002376 immune system process
1.56 6.22e-04 GO:0065007 biological regulation
7.73 1.69e-03 GO:0019221 cytokine-mediated signaling pathway
2.33 1.73e-03 GO:0006950 response to stress
1.58 2.88e-03 GO:0050794 regulation of cellular process
6.97 3.92e-03 GO:0071345 cellular response to cytokine stimulus
1.54 4.50e-03 GO:0050789 regulation of biological process
5.59 8.27e-03 GO:0034097 response to cytokine stimulus
3.31 8.84e-03 GO:0009611 response to wounding
3.43 1.05e-02 GO:0006952 defense response
8.57 1.19e-02 GO:0032496 response to lipopolysaccharide
3.49 1.63e-02 GO:0006955 immune response
7.79 2.20e-02 GO:0002237 response to molecule of bacterial origin
1.84 2.99e-02 GO:0023052 signaling
5.35 3.22e-02 GO:0006954 inflammatory response
1.88 4.71e-02 GO:0007165 signal transduction

Nothing significant found in compartment category.

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
1.44 2.42e-02 GO:0005515 protein binding