Motif ID: CDC5L.p2

Z-value: 1.233


Transcription factors associated with CDC5L.p2:

Gene SymbolEntrez IDGene Name
CDC5L 988 CDC5 cell division cycle 5-like (S. pombe)

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
CDC5Lhg19_v1_chr6_+_44355440_443555600.202.8e-01Click!


Activity profile for motif CDC5L.p2.

activity profile for motif CDC5L.p2


Sorted Z-values histogram for motif CDC5L.p2

Sorted Z-values for motif CDC5L.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of CDC5L.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr2_+_167744996 7.236 NM_001079810
NM_001199143
NM_152381
 XIRP2


xin actin-binding repeat containing 2


chr10_-_21186530 6.871 NM_006393
 NEBL
nebulette
chr7_+_123295860 4.539 NM_207163
 LMOD2
leiomodin 2 (cardiac)
chr18_-_24445652 4.033 NM_001650
 AQP4
aquaporin 4
chr14_-_23877480 4.007 NM_002471
 MYH6
myosin, heavy chain 6, cardiac muscle, alpha
chr11_-_13517525 3.727 NM_000315
 PTH
parathyroid hormone
chr4_+_41614933 3.604 LIMCH1
LIM and calponin homology domains 1
chr3_+_35721115 3.603 NM_001025068
NM_001025069
 ARPP21

cAMP-regulated phosphoprotein, 21kDa

chr17_+_4487275 3.441 NM_198501
 SMTNL2
smoothelin-like 2
chr7_-_113559048 3.245 NM_002711
 PPP1R3A
protein phosphatase 1, regulatory subunit 3A
chr12_-_111358353 2.984 NM_000432
 MYL2
myosin, light chain 2, regulatory, cardiac, slow
chr4_+_41614911 2.912 NM_001112719
NM_001112720
 LIMCH1

LIM and calponin homology domains 1

chr20_+_20037289 2.857 NM_001167816
 C20orf26
chromosome 20 open reading frame 26
chr2_-_161056573 2.632 NM_000888
 ITGB6
integrin, beta 6
chr2_-_161056762 2.500 ITGB6
integrin, beta 6
chr2_-_211179765 2.410 NM_079420
 MYL1
myosin, light chain 1, alkali; skeletal, fast
chr8_-_107782417 2.352 NM_139166
 ABRA
actin-binding Rho activating protein
chr4_+_41614725 2.192 LIMCH1
LIM and calponin homology domains 1
chr4_-_177190258 2.059 NM_080874
 ASB5
ankyrin repeat and SOCS box containing 5
chr2_-_179659680 1.939 TTN
titin

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 37 entries
Enrichment   P-value GO Accession GO Term
173.23 1.39e-02 GO:0048739 cardiac muscle fiber development
162.40 1.67e-04 GO:0055003 cardiac myofibril assembly
118.12 4.90e-04 GO:0045214 sarcomere organization
99.95 8.46e-04 GO:0055006 cardiac cell development
99.95 8.46e-04 GO:0055013 cardiac muscle cell development
82.50 3.65e-05 GO:0030239 myofibril assembly
80.21 9.91e-07 GO:0031032 actomyosin structure organization
70.24 5.53e-08 GO:0030049 muscle filament sliding
70.24 5.53e-08 GO:0033275 actin-myosin filament sliding
68.39 6.56e-08 GO:0070252 actin-mediated cell contraction
56.50 5.16e-03 GO:0055007 cardiac muscle cell differentiation
50.97 4.19e-07 GO:0030048 actin filament-based movement
44.21 2.26e-05 GO:0055002 striated muscle cell development
41.93 1.29e-02 GO:0035051 cardiac cell differentiation
41.93 1.29e-02 GO:0055008 cardiac muscle tissue morphogenesis
40.62 1.42e-02 GO:0048747 muscle fiber development
40.62 1.42e-02 GO:0060415 muscle tissue morphogenesis
39.39 4.08e-05 GO:0055001 muscle cell development
35.13 2.21e-02 GO:0006941 striated muscle contraction
34.21 2.40e-02 GO:0048644 muscle organ morphogenesis

Gene overrepresentation in compartment category:

Showing 1 to 10 of 10 entries
Enrichment   P-value GO Accession GO Term
66.64 2.23e-02 GO:0005865 striated muscle thin filament
48.14 4.34e-02 GO:0005859 muscle myosin complex
48.14 4.34e-02 GO:0032982 myosin filament
27.09 7.49e-04 GO:0016459 myosin complex
26.54 4.70e-06 GO:0030017 sarcomere
26.15 3.87e-07 GO:0030016 myofibril
24.67 5.83e-07 GO:0043292 contractile fiber
23.02 1.10e-05 GO:0044449 contractile fiber part
12.14 1.18e-05 GO:0015629 actin cytoskeleton
3.64 2.88e-03 GO:0005856 cytoskeleton

Gene overrepresentation in function category:

Showing 1 to 5 of 5 entries
Enrichment   P-value GO Accession GO Term
96.25 1.39e-02 GO:0005283 sodium:amino acid symporter activity
78.75 2.12e-02 GO:0005416 cation:amino acid symporter activity
60.44 4.00e-08 GO:0008307 structural constituent of muscle
13.82 1.06e-07 GO:0003779 actin binding
10.11 6.32e-08 GO:0008092 cytoskeletal protein binding