Motif ID: CDX1,2,4.p2

Z-value: 1.859


Transcription factors associated with CDX1,2,4.p2:

Gene SymbolEntrez IDGene Name
CDX1 1044 caudal type homeobox 1
CDX2 1045 caudal type homeobox 2
CDX4 1046 caudal type homeobox 4

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
CDX1hg19_v1_chr5_+_149546340_1495464370.383.2e-02Click!
CDX4hg19_v1_chrX_+_72667089_726670890.336.4e-02Click!
CDX2hg19_v1_chr13_-_28543423_285435040.173.7e-01Click!


Activity profile for motif CDX1,2,4.p2.

activity profile for motif CDX1,2,4.p2


Sorted Z-values histogram for motif CDX1,2,4.p2

Sorted Z-values for motif CDX1,2,4.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of CDX1,2,4.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr12_-_122107559 7.087 NM_173855
 MORN3
MORN repeat containing 3
chr1_-_67594219 5.333 NM_001013674
 C1orf141
chromosome 1 open reading frame 141
chr7_+_151653463 5.143 NM_145292
 GALNTL5
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 5
chr8_+_24151579 5.081 NM_014265
NM_021777
 ADAM28

ADAM metallopeptidase domain 28

chr10_+_32856650 4.736 NM_024688
 C10orf68
chromosome 10 open reading frame 68
chr3_+_107096187 4.138 NM_032600
 CCDC54
coiled-coil domain containing 54
chr6_-_130544098 3.989 NM_001017373
 SAMD3
sterile alpha motif domain containing 3
chr3_+_108541544 3.920 NM_016388
 TRAT1
T cell receptor associated transmembrane adaptor 1
chr22_+_23054862 3.629 IGLV3-21
IGLJ3
IGLC1
immunoglobulin lambda variable 3-21
immunoglobulin lambda joining 3
immunoglobulin lambda constant 1 (Mcg marker)
chr5_+_94727047 3.589 NM_152548
 FAM81B
family with sequence similarity 81, member B
chr11_+_7110164 3.467 NM_014469
 RBMXL2
RNA binding motif protein, X-linked-like 2
chr10_+_97759847 3.442 NM_001001732
NM_001159747
 CC2D2B

coiled-coil and C2 domain containing 2B

chr1_+_160709038 3.274 NM_021181
 SLAMF7
SLAM family member 7
chr14_-_106452693 3.167 IGHG1
immunoglobulin heavy constant gamma 1 (G1m marker)
chr3_+_57094468 3.104 NM_181727
 SPATA12
spermatogenesis associated 12
chr6_-_49834188 3.047 NM_001131
NM_170609
 CRISP1

cysteine-rich secretory protein 1

chr17_-_34195745 2.992 NM_152781
 C17orf66
chromosome 17 open reading frame 66
chr12_+_49297892 2.983 NM_033124
 CCDC65
coiled-coil domain containing 65
chr9_-_139927291 2.877 NM_004479
 FUT7
fucosyltransferase 7 (alpha (1,3) fucosyltransferase)
chr18_-_51880942 2.828 NM_139171
 STARD6
StAR-related lipid transfer (START) domain containing 6

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 39 entries
Enrichment   P-value GO Accession GO Term
46.70 1.50e-02 GO:0050857 positive regulation of antigen receptor-mediated signaling pathway
24.58 7.02e-05 GO:0050853 B cell receptor signaling pathway
18.32 4.01e-02 GO:0030101 natural killer cell activation
12.29 5.84e-03 GO:0030888 regulation of B cell proliferation
11.80 4.25e-02 GO:0046651 lymphocyte proliferation
10.09 3.91e-03 GO:0006968 cellular defense response
8.79 9.97e-03 GO:0031294 lymphocyte costimulation
8.79 9.97e-03 GO:0031295 T cell costimulation
8.52 1.23e-02 GO:0007338 single fertilization
8.16 7.14e-05 GO:0002768 immune response-regulating cell surface receptor signaling pathway
7.71 4.72e-04 GO:0002429 immune response-activating cell surface receptor signaling pathway
7.69 6.55e-03 GO:0009566 fertilization
6.70 1.82e-02 GO:0050851 antigen receptor-mediated signaling pathway
6.39 8.54e-04 GO:0050870 positive regulation of T cell activation
6.31 1.09e-05 GO:0046649 lymphocyte activation
6.23 3.08e-02 GO:0050670 regulation of lymphocyte proliferation
6.19 4.25e-05 GO:0002696 positive regulation of leukocyte activation
6.17 1.34e-04 GO:0051251 positive regulation of lymphocyte activation
6.17 3.31e-02 GO:0032944 regulation of mononuclear cell proliferation
6.09 5.26e-05 GO:0050867 positive regulation of cell activation

Gene overrepresentation in compartment category:

Showing 1 to 3 of 3 entries
Enrichment   P-value GO Accession GO Term
6.21 1.99e-04 GO:0009897 external side of plasma membrane
2.99 3.25e-02 GO:0009986 cell surface
2.08 2.13e-05 GO:0005576 extracellular region

Gene overrepresentation in function category:

Showing 1 to 6 of 6 entries
Enrichment   P-value GO Accession GO Term
13.62 1.13e-04 GO:0003823 antigen binding
4.51 5.73e-03 GO:0005529 sugar binding
2.99 4.40e-02 GO:0030246 carbohydrate binding
1.98 3.01e-03 GO:0004872 receptor activity
1.78 1.41e-02 GO:0004871 signal transducer activity
1.78 1.41e-02 GO:0060089 molecular transducer activity