Motif ID: CEBPA,B_DDIT3.p2

Z-value: 1.872


Transcription factors associated with CEBPA,B_DDIT3.p2:

Gene SymbolEntrez IDGene Name
CEBPA 1050 CCAAT/enhancer binding protein (C/EBP), alpha
CEBPB 1051 CCAAT/enhancer binding protein (C/EBP), beta
DDIT3 1649 DNA-damage-inducible transcript 3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
DDIT3hg19_v1_chr12_-_57914287_57914302-0.327.0e-02Click!
CEBPBhg19_v1_chr20_+_48807460_488078010.163.7e-01Click!
CEBPAhg19_v1_chr19_-_33793429_337934370.144.4e-01Click!


Activity profile for motif CEBPA,B_DDIT3.p2.

activity profile for motif CEBPA,B_DDIT3.p2


Sorted Z-values histogram for motif CEBPA,B_DDIT3.p2

Sorted Z-values for motif CEBPA,B_DDIT3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of CEBPA,B_DDIT3.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr8_+_22019167 7.931 NM_001172357
NM_001172410
NM_003018
SFTPC


surfactant protein C


chr19_-_51920841 7.482 NM_001171156
NM_001171157
NM_001171158
NM_001171159
NM_001171160
NM_001171161
NM_033130
SIGLEC10






sialic acid binding Ig-like lectin 10






chr17_-_34524054 6.877 NM_001001437
NM_021006
CCL3L3
CCL3
CCL3L1
chemokine (C-C motif) ligand 3-like 3
chemokine (C-C motif) ligand 3
chemokine (C-C motif) ligand 3-like 1
chr9_+_117085302 6.868 NM_000607
ORM1
orosomucoid 1
chr9_+_117092068 6.792 NM_000608
ORM2
orosomucoid 2
chr5_-_140013285 6.636 NM_001040021
NM_001174104
NM_001174105
CD14


CD14 molecule


chr5_-_140012730 6.563 CD14
CD14 molecule
chr4_-_38806410 6.446 NM_003263
TLR1
toll-like receptor 1
chr20_+_54987167 6.371 NM_001164116
NM_001164114
NM_001164115
NM_020356
CASS4



Cas scaffolding protein family member 4



chr6_+_12717036 6.237 NM_001242648
NM_030948
PHACTR1

phosphatase and actin regulator 1

chr20_+_57766074 6.086 NM_178457
ZNF831
zinc finger protein 831
chr19_+_41430123 5.976 CYP2B7P1
cytochrome P450, family 2, subfamily B, polypeptide 7 pseudogene 1
chr3_+_186330859 5.971 AHSG
alpha-2-HS-glycoprotein
chr19_+_45452427 5.901 APOC2
apolipoprotein C-II
chr2_-_113594325 5.702 NM_000576
IL1B
interleukin 1, beta
chr3_+_186330844 5.657 NM_001622
AHSG
alpha-2-HS-glycoprotein
chr17_-_64225496 5.387 NM_000042
APOH
apolipoprotein H (beta-2-glycoprotein I)
chr9_+_80911990 5.356 NM_021154
NM_058179
PSAT1

phosphoserine aminotransferase 1

chr20_+_24929904 5.177 CST7
cystatin F (leukocystatin)
chr6_+_131894343 5.148 NM_000045
NM_001244438
ARG1

arginase, liver

chr16_-_21663962 4.682 NM_005849
IGSF6
immunoglobulin superfamily, member 6
chr3_+_186330711 4.664 AHSG
alpha-2-HS-glycoprotein
chr14_+_21423627 4.538 NM_002934
RNASE2
ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin)
chr17_-_34207308 4.319 NM_002985
CCL5
chemokine (C-C motif) ligand 5
chr19_+_6887576 4.304 NM_001974
EMR1
egf-like module containing, mucin-like, hormone receptor-like 1
chr18_+_61637262 4.238 NM_001031848
NM_002640
NM_198833
SERPINB8


serpin peptidase inhibitor, clade B (ovalbumin), member 8


chr5_-_66492574 4.230 NM_005582
CD180
CD180 molecule
chr11_+_59824054 4.224 NM_001031666
NM_001031809
NM_006138
MS4A3


membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)


chr11_+_59824129 4.165 MS4A3
membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)
chr14_+_21359542 3.968 NM_002935
RNASE3
ribonuclease, RNase A family, 3
chr20_+_24929862 3.940 NM_003650
CST7
cystatin F (leukocystatin)
chr19_+_47813074 3.889 NM_001736
C5AR1
complement component 5a receptor 1
chr9_-_71590754 3.795


chr11_-_33913835 3.750 NM_005574
LMO2
LIM domain only 2 (rhombotin-like 1)
chr12_-_113841654 3.712 NM_006843
SDS
serine dehydratase
chr8_-_17743062 3.606 FGL1
fibrinogen-like 1
chr11_+_67777788 3.577 NM_000694
NM_001030010
ALDH3B1

aldehyde dehydrogenase 3 family, member B1

chr3_+_46395574 3.567 CCR2
chemokine (C-C motif) receptor 2
chr5_-_140013034 3.548 NM_000591
CD14
CD14 molecule
chr4_+_40198526 3.483 NM_004310
RHOH
ras homolog gene family, member H
chr11_+_67777795 3.462 ALDH3B1
aldehyde dehydrogenase 3 family, member B1
chr4_+_187187342 3.287 F11
coagulation factor XI
chr3_+_1134619 3.199 NM_014461
CNTN6
contactin 6
chr6_-_116447225 3.178 NM_000493
COL10A1
collagen, type X, alpha 1
chr19_-_44174497 3.159 NM_001005376
NM_001005377
NM_002659
PLAUR


plasminogen activator, urokinase receptor


chr11_-_104972147 3.057 NM_001007232
NM_001223
NM_033292
NM_033293
NM_033294
NM_033295
CARD17
CASP1




caspase recruitment domain family, member 17
caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)




chr3_+_46395224 3.036 NM_001123041
NM_001123396
CCR2

chemokine (C-C motif) receptor 2

chr16_+_27438578 3.028 NM_021798
IL21R
interleukin 21 receptor
chr19_+_41497182 2.895 NM_000767
CYP2B6
cytochrome P450, family 2, subfamily B, polypeptide 6
chr19_+_1450208 2.864 APC2
adenomatosis polyposis coli 2
chr11_+_71846755 2.862 NM_000804
FOLR3
folate receptor 3 (gamma)
chr22_+_23054862 2.853 IGLV3-21
IGLJ3
IGLC1
immunoglobulin lambda variable 3-21
immunoglobulin lambda joining 3
immunoglobulin lambda constant 1 (Mcg marker)
chr6_-_41254392 2.751 NM_001242589
NM_001242590
NM_018643
TREM1


triggering receptor expressed on myeloid cells 1


chr9_-_117156684 2.666 NM_030767
AKNA
AT-hook transcription factor
chr1_+_192127591 2.638 NM_130782
RGS18
regulator of G-protein signaling 18
chr14_-_68162419 2.541 NM_001252650
NM_016026
RDH11

retinol dehydrogenase 11 (all-trans/9-cis/11-cis)

chr10_-_73497580 2.503 NM_001168390
C10orf105
chromosome 10 open reading frame 105
chr2_+_128175989 2.493 NM_000312
PROC
protein C (inactivator of coagulation factors Va and VIIIa)
chr7_+_90339146 2.487 CDK14
cyclin-dependent kinase 14
chr12_-_49259549 2.468 NM_014470
RND1
Rho family GTPase 1
chr6_+_12716887 2.461 PHACTR1
phosphatase and actin regulator 1
chr22_-_17700265 2.404 CECR1
cat eye syndrome chromosome region, candidate 1
chrX_-_153095332 2.397 PDZD4
PDZ domain containing 4
chr18_-_67624159 2.386 NM_006566
CD226
CD226 molecule
chr5_-_94224601 2.381 MCTP1
multiple C2 domains, transmembrane 1
chr7_-_111428944 2.372 DOCK4
dedicator of cytokinesis 4
chr17_-_77813049 2.364 NM_003655
CBX4
chromobox homolog 4
chrX_-_105282714 2.338 NM_000354
SERPINA7
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7
chr1_+_111770280 2.313 NM_001025197
NM_004000
CHI3L2

chitinase 3-like 2

chr5_+_57787260 2.241 NM_152687
GAPT
GRB2-binding adaptor protein, transmembrane
chr8_-_27115935 2.236 STMN4
stathmin-like 4
chr3_-_148939784 2.220 NM_000096
CP
ceruloplasmin (ferroxidase)
chr11_+_63057371 2.185 NM_001039752
SLC22A10
solute carrier family 22, member 10
chr22_+_35779103 2.153 HMOX1
heme oxygenase (decycling) 1
chr9_-_123812535 2.146 NM_001735
C5
complement component 5
chr15_-_55563091 2.132 NM_183236
RAB27A
RAB27A, member RAS oncogene family
chr12_-_10151689 2.082 NM_001099431
NM_016509
CLEC1B

C-type lectin domain family 1, member B

chr6_+_32605182 2.078 NM_002122
HLA-DQA1
major histocompatibility complex, class II, DQ alpha 1
chr3_+_130569368 2.072 NM_001199180
NM_001199181
NM_001199182
ATP2C1


ATPase, Ca++ transporting, type 2C, member 1


chr19_-_4302381 2.070 NM_001169126
NM_144615
TMIGD2

transmembrane and immunoglobulin domain containing 2

chr4_+_108814419 2.063 NM_001136257
NM_152621
SGMS2

sphingomyelin synthase 2

chr17_+_4337218 2.030 NM_182538
SPNS3
spinster homolog 3 (Drosophila)
chr21_-_15918635 2.029 NM_022136
SAMSN1
SAM domain, SH3 domain and nuclear localization signals 1
chr22_+_40297085 1.977 NM_004810
GRAP2
GRB2-related adaptor protein 2
chr17_-_34625628 1.976 NM_001001437
NM_021006
CCL3L3
CCL3
CCL3L1
chemokine (C-C motif) ligand 3-like 3
chemokine (C-C motif) ligand 3
chemokine (C-C motif) ligand 3-like 1
chr1_-_173933176 1.961 RC3H1
ring finger and CCCH-type domains 1
chr12_-_63328857 1.952 PPM1H
protein phosphatase, Mg2+/Mn2+ dependent, 1H
chr4_+_187187117 1.945 NM_000128
F11
coagulation factor XI
chr1_+_150954498 1.944 NM_003568
ANXA9
annexin A9
chrX_-_40506666 1.943 CXorf38
chromosome X open reading frame 38
chrX_-_40506800 1.899 NM_144970
CXorf38
chromosome X open reading frame 38
chr16_-_21663908 1.890 IGSF6
immunoglobulin superfamily, member 6
chr3_+_186435097 1.873 NM_000893
NM_001102416
NM_001166451
KNG1


kininogen 1


chr3_+_32993065 1.858 NM_005508
CCR4
chemokine (C-C motif) receptor 4
chr12_-_53074172 1.829 NM_006121
KRT1
keratin 1
chr19_-_53233134 1.765 NM_030972
ZNF611
zinc finger protein 611
chrX_+_144908927 1.764 NM_004709
CXorf1
chromosome X open reading frame 1
chr5_+_161275897 1.758 NM_001127646
GABRA1
gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr11_+_67171400 1.755 NM_198517
TBC1D10C
TBC1 domain family, member 10C
chr4_-_71532341 1.749 NM_144646
IGJ
immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
chr16_+_27341305 1.730 IL4R
interleukin 4 receptor
chr3_+_186739643 1.705 NM_003032
ST6GAL1
ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
chr22_+_40297183 1.666 GRAP2
GRB2-related adaptor protein 2
chr16_-_18798077 1.624


chr4_-_153601085 1.592 NM_152680
TMEM154
transmembrane protein 154
chr1_+_161676761 1.587 NM_001184866
NM_001184867
NM_001184870
NM_001184871
NM_001184872
NM_001184873
NM_032738
FCRLA






Fc receptor-like A






chr7_-_37024664 1.582 NM_001039459
ELMO1
engulfment and cell motility 1
chr4_-_10023094 1.580 NM_020041
SLC2A9
solute carrier family 2 (facilitated glucose transporter), member 9
chr19_-_47128293 1.550 NM_000960
PTGIR
prostaglandin I2 (prostacyclin) receptor (IP)
chr12_+_65224214 1.543


chr1_-_1711453 1.543 NM_001198994
NADK
NAD kinase
chr17_+_56315786 1.526 NM_001160102
NM_006151
LPO

lactoperoxidase

chr1_+_84630374 1.522 PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr18_+_29598444 1.521 NM_017831
RNF125
ring finger protein 125
chr19_-_8567473 1.512 NM_032152
PRAM1
PML-RARA regulated adaptor molecule 1
chr15_+_89182038 1.501 NM_002201
ISG20
interferon stimulated exonuclease gene 20kDa
chr14_-_74226634 1.496 C14orf43
chromosome 14 open reading frame 43
chr5_-_176836488 1.478 F12
coagulation factor XII (Hageman factor)
chr2_+_191301020 1.452 MFSD6
major facilitator superfamily domain containing 6
chr8_-_27115897 1.452 NM_030795
STMN4
stathmin-like 4
chr20_+_5987897 1.435 NM_001127458
CRLS1
cardiolipin synthase 1
chr20_+_32150139 1.434 NM_001039709
NM_005093
CBFA2T2

core-binding factor, runt domain, alpha subunit 2; translocated to, 2

chr20_+_19955778 1.411 RIN2
Ras and Rab interactor 2
chr1_+_196857143 1.403 NM_001201550
NM_001201551
NM_006684
CFHR4


complement factor H-related 4


chr12_-_121736110 1.399 NM_006549
NM_153499
NM_153500
NM_172214
NM_172215
NM_172216
CAMKK2





calcium/calmodulin-dependent protein kinase kinase 2, beta





chr11_-_116663106 1.383 NM_001166598
NM_052968
APOA5

apolipoprotein A-V

chr6_+_80340971 1.378 NM_031469
SH3BGRL2
SH3 domain binding glutamic acid-rich protein like 2
chr2_-_158731622 1.373 NM_001105
ACVR1
activin A receptor, type I
chr12_-_9885859 1.353 NM_001253748
NM_001253750
NM_172004
CLECL1


C-type lectin-like 1


chr7_+_28338939 1.351 NM_182899
CREB5
cAMP responsive element binding protein 5
chr16_+_24266873 1.331 NM_006539
CACNG3
calcium channel, voltage-dependent, gamma subunit 3
chr19_-_14785626 1.328 NM_032571
EMR3
egf-like module containing, mucin-like, hormone receptor-like 3
chr2_+_219246751 1.314 NM_000578
SLC11A1
solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1
chr2_-_21231406 1.298 APOB
apolipoprotein B (including Ag(x) antigen)
chr1_-_151826042 1.267 NM_182578
THEM5
thioesterase superfamily member 5
chr11_+_2323356 1.266 TSPAN32
tetraspanin 32
chr12_-_58135853 1.262 NM_014770
AGAP2
ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
chr14_-_106780535 1.249 IGHA1
IGHA2
IGHD
IGHG1
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant alpha 2 (A2m marker)
immunoglobulin heavy constant delta
immunoglobulin heavy constant gamma 1 (G1m marker)
chr1_-_55331350 1.240 DHCR24
24-dehydrocholesterol reductase
chr20_+_361938 1.236 TRIB3
tribbles homolog 3 (Drosophila)
chr11_-_84634219 1.217 DLG2
discs, large homolog 2 (Drosophila)
chr19_+_39786964 1.204 NM_172140
IL29
interleukin 29 (interferon, lambda 1)
chr19_-_18197632 1.199 NM_005535
NM_153701
IL12RB1

interleukin 12 receptor, beta 1

chr12_+_7060433 1.196 NM_002831
NM_080549
PTPN6

protein tyrosine phosphatase, non-receptor type 6

chr7_+_90338711 1.195 NM_012395
CDK14
cyclin-dependent kinase 14
chr1_+_236681513 1.179 NM_201545
LGALS8
lectin, galactoside-binding, soluble, 8
chr1_+_66258192 1.170 NM_001037341
PDE4B
phosphodiesterase 4B, cAMP-specific
chr3_-_42305438 1.169 NM_001174138
CCK
cholecystokinin
chr17_-_72709010 1.168 NM_139018
CD300LF
CD300 molecule-like family member f
chr6_+_31895201 1.165 NM_000063
NM_001145903
C2

complement component 2

chr2_+_204571379 1.160 CD28
CD28 molecule
chr9_+_130860769 1.155 SLC25A25
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25
chr16_-_30394133 1.150 NM_052838
SEPT1
septin 1
chrX_+_37639306 1.145 CYBB
cytochrome b-245, beta polypeptide
chr14_-_106452693 1.144 IGHG1
immunoglobulin heavy constant gamma 1 (G1m marker)
chr2_-_21228189 1.143 APOB
apolipoprotein B (including Ag(x) antigen)
chr6_+_31895401 1.138 C2
complement component 2
chr18_+_21032786 1.108 NM_003831
RIOK3
RIO kinase 3 (yeast)
chr9_-_130712866 1.106 NM_203305
FAM102A
family with sequence similarity 102, member A
chr12_+_15699544 1.099 PTPRO
protein tyrosine phosphatase, receptor type, O
chr11_-_104916041 1.096 NM_001017534
NM_052889
CARD16

caspase recruitment domain family, member 16

chr14_-_107199126 1.092 IGHG3
immunoglobulin heavy constant gamma 3 (G3m marker)
chr7_+_73624086 1.077 NM_014146
NM_032463
NM_032464
LAT2


linker for activation of T cells family, member 2


chr1_+_153330329 1.073 NM_002965
S100A9
S100 calcium binding protein A9
chr19_-_7796977 1.070 NM_001244856
NM_198492
CLEC4G

C-type lectin domain family 4, member G

chr19_-_54876410 1.060 LAIR1
leukocyte-associated immunoglobulin-like receptor 1
chr14_-_60337350 1.025 NM_021136
RTN1
reticulon 1
chr6_+_167525294 1.021 NM_004367
CCR6
chemokine (C-C motif) receptor 6
chr11_-_2323066 1.021 NM_001142946
C11orf21
chromosome 11 open reading frame 21
chr4_+_159131400 1.016 NM_018342
TMEM144
transmembrane protein 144
chr7_+_26400503 1.014 NM_001199837
SNX10
sorting nexin 10
chr3_+_149192479 1.012 TM4SF4
transmembrane 4 L six family member 4
chr8_-_27941387 1.008 NM_001010906
C8orf80
chromosome 8 open reading frame 80
chr1_-_116383692 0.999 NM_005599
NHLH2
nescient helix loop helix 2
chr5_-_24645084 0.993 NM_006727
CDH10
cadherin 10, type 2 (T2-cadherin)
chr12_-_122296619 0.988 NM_002150
HPD
4-hydroxyphenylpyruvate dioxygenase
chr3_-_42843217 0.984


chr12_-_54758228 0.975 NM_020370
GPR84
G protein-coupled receptor 84
chr2_+_234296799 0.966 NM_003648
DGKD
diacylglycerol kinase, delta 130kDa
chr1_+_24834083 0.961 NM_001251978
RCAN3
RCAN family member 3
chr1_-_173962050 0.961 NM_172071
RC3H1
ring finger and CCCH-type domains 1
chr4_+_141178439 0.946 NM_032547
SCOC
short coiled-coil protein
chr20_+_62795826 0.945 NM_004535
MYT1
myelin transcription factor 1
chr22_+_22723972 0.944


chr3_-_150920946 0.942 NM_013308
GPR171
G protein-coupled receptor 171
chr2_-_37297372 0.941 HEATR5B
HEAT repeat containing 5B
chr11_-_104905849 0.941 CASP1
caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)
chr19_-_50868877 0.930 NM_004851
NAPSA
napsin A aspartic peptidase
chr1_+_40859016 0.929 NM_001198979
SMAP2
small ArfGAP2
chr14_-_106494166 0.925 IGHV4-31
IGHA1
immunoglobulin heavy variable 4-31
immunoglobulin heavy constant alpha 1
chr11_+_67171379 0.921 TBC1D10C
TBC1 domain family, member 10C
chr1_+_66458389 0.916 NM_001037340
PDE4B
phosphodiesterase 4B, cAMP-specific
chr8_+_24151579 0.913 NM_014265
NM_021777
ADAM28

ADAM metallopeptidase domain 28

chr12_-_15114495 0.899 NM_001175
ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
chr1_-_40563141 0.899 NM_000310
NM_001142604
PPT1

palmitoyl-protein thioesterase 1

chr9_+_116342939 0.886 NM_021106
RGS3
regulator of G-protein signaling 3
chr7_-_115608366 0.882 NM_001244583
TFEC
transcription factor EC
chr15_-_73051650 0.881


chr1_+_248058857 0.858 NM_001001957
OR2W3
olfactory receptor, family 2, subfamily W, member 3
chr16_+_56966025 0.838 HERPUD1
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
5.50 4.99e-13 GO:0006955 immune response
4.08 6.08e-12 GO:0002376 immune system process
4.91 3.44e-11 GO:0006952 defense response
8.10 1.79e-09 GO:0006954 inflammatory response
4.32 2.71e-09 GO:0009611 response to wounding
28.34 3.10e-06 GO:0030195 negative regulation of blood coagulation
27.36 4.06e-06 GO:0050819 negative regulation of coagulation
2.40 4.57e-06 GO:0006950 response to stress
1.69 5.85e-06 GO:0050896 response to stimulus
7.29 6.68e-06 GO:0032101 regulation of response to external stimulus
5.01 1.67e-05 GO:0002684 positive regulation of immune system process
3.96 2.80e-05 GO:0002682 regulation of immune system process
20.35 3.72e-05 GO:0030193 regulation of blood coagulation
14.87 5.08e-05 GO:0072376 protein activation cascade
18.90 6.38e-05 GO:0050818 regulation of coagulation
5.39 1.07e-04 GO:0051240 positive regulation of multicellular organismal process
16.53 1.67e-04 GO:0061041 regulation of wound healing
2.43 2.72e-04 GO:0048583 regulation of response to stimulus
4.96 3.09e-04 GO:0045087 innate immune response
4.41 6.03e-04 GO:0050776 regulation of immune response
50.38 6.12e-04 GO:0031638 zymogen activation
5.44 6.91e-04 GO:0050778 positive regulation of immune response
5.87 8.49e-04 GO:0051241 negative regulation of multicellular organismal process
85.01 2.33e-03 GO:0031639 plasminogen activation
37.79 2.36e-03 GO:0002825 regulation of T-helper 1 type immune response
7.62 2.44e-03 GO:0050870 positive regulation of T cell activation
6.45 3.06e-03 GO:0002696 positive regulation of leukocyte activation
3.86 3.43e-03 GO:0080134 regulation of response to stress
6.34 3.56e-03 GO:0050867 positive regulation of cell activation
3.61 4.10e-03 GO:0042060 wound healing
5.47 4.78e-03 GO:0002694 regulation of leukocyte activation
9.92 5.69e-03 GO:0006959 humoral immune response
30.23 6.37e-03 GO:0010574 regulation of vascular endothelial growth factor production
2.56 6.89e-03 GO:0051239 regulation of multicellular organismal process
5.27 6.91e-03 GO:0050865 regulation of cell activation
12.15 8.22e-03 GO:0002822 regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
2.07 9.03e-03 GO:0042221 response to chemical stimulus
11.94 9.12e-03 GO:0002819 regulation of adaptive immune response
26.67 1.09e-02 GO:0007597 blood coagulation, intrinsic pathway
16.20 1.13e-02 GO:0002824 positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
6.23 1.27e-02 GO:0051251 positive regulation of lymphocyte activation
2.93 1.29e-02 GO:0040011 locomotion
15.75 1.30e-02 GO:0002821 positive regulation of adaptive immune response
6.15 1.40e-02 GO:0050863 regulation of T cell activation
4.88 1.43e-02 GO:0001817 regulation of cytokine production
8.36 1.77e-02 GO:0045765 regulation of angiogenesis
48.58 2.00e-02 GO:0010758 regulation of macrophage chemotaxis
22.67 2.18e-02 GO:0072378 blood coagulation, fibrin clot formation
2.67 2.98e-02 GO:0009605 response to external stimulus
1.76 3.11e-02 GO:0007165 signal transduction
42.51 3.17e-02 GO:0002827 positive regulation of T-helper 1 type immune response
42.51 3.17e-02 GO:0051006 positive regulation of lipoprotein lipase activity
6.39 3.18e-02 GO:0002237 response to molecule of bacterial origin
6.17 4.08e-02 GO:0002697 regulation of immune effector process
9.07 4.45e-02 GO:0002699 positive regulation of immune effector process

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
4.72 3.61e-11 GO:0005615 extracellular space
2.86 5.67e-10 GO:0005576 extracellular region
3.75 6.27e-09 GO:0044421 extracellular region part
37.79 3.19e-04 GO:0042627 chylomicron
22.67 2.95e-03 GO:0034361 very-low-density lipoprotein particle
22.67 2.95e-03 GO:0034385 triglyceride-rich lipoprotein particle
12.96 2.88e-02 GO:0032994 protein-lipid complex
12.96 2.88e-02 GO:0034358 plasma lipoprotein particle
1.54 3.74e-02 GO:0071944 cell periphery

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
22.67 3.06e-07 GO:0003823 antigen binding
113.34 1.15e-04 GO:0060230 lipoprotein lipase activator activity
5.01 8.75e-04 GO:0004857 enzyme inhibitor activity
2.80 1.82e-03 GO:0030234 enzyme regulator activity
56.67 2.27e-03 GO:0060229 lipase activator activity
4.04 3.50e-03 GO:0030246 carbohydrate binding
14.17 4.35e-03 GO:0004869 cysteine-type endopeptidase inhibitor activity
5.55 6.22e-03 GO:0061134 peptidase regulator activity
6.22 7.66e-03 GO:0004866 endopeptidase inhibitor activity
5.97 1.02e-02 GO:0061135 endopeptidase regulator activity
5.89 1.12e-02 GO:0030414 peptidase inhibitor activity
11.12 1.44e-02 GO:0042379 chemokine receptor binding
1.94 2.04e-02 GO:0004871 signal transducer activity
1.94 2.04e-02 GO:0060089 molecular transducer activity
5.04 3.31e-02 GO:0005126 cytokine receptor binding