Motif ID: CTCF.p2

Z-value: 1.665


Transcription factors associated with CTCF.p2:

Gene SymbolEntrez IDGene Name
CTCF 10664 CCCTC-binding factor (zinc finger protein)

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
CTCFhg19_v1_chr16_+_67596309_675964790.503.7e-03Click!


Activity profile for motif CTCF.p2.

activity profile for motif CTCF.p2


Sorted Z-values histogram for motif CTCF.p2

Sorted Z-values for motif CTCF.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of CTCF.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr22_+_22697538 3.542


chr14_-_107083398 2.808 IGH@
IGHA1
IGHG1
immunoglobulin heavy locus
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
chr22_+_22550159 2.766 IGLV6-57
immunoglobulin lambda variable 6-57
chr14_-_106877689 2.471 IGHV4-31
IGH@
IGHA1
IGHA2
IGHG1
IGHG4
IGHM
immunoglobulin heavy variable 4-31
immunoglobulin heavy locus
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant alpha 2 (A2m marker)
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant gamma 4 (G4m marker)
immunoglobulin heavy constant mu
chr14_-_106610338 2.454 IGHV4-31
IGHG1
immunoglobulin heavy variable 4-31
immunoglobulin heavy constant gamma 1 (G1m marker)
chr22_+_22550112 2.447


chr22_+_22723972 2.015


chr14_-_106573348 1.932 IGHV4-31
IGHA1
IGHA2
IGHG1
IGHG3
IGHM
immunoglobulin heavy variable 4-31
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant alpha 2 (A2m marker)
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant gamma 3 (G3m marker)
immunoglobulin heavy constant mu
chr19_+_49977465 1.776 NM_001204502
NM_001459
FLT3LG

fms-related tyrosine kinase 3 ligand

chr14_-_106518424 1.775 IGH@
IGHA1
IGHG1
IGHG2
IGHM
immunoglobulin heavy locus
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant gamma 2 (G2m marker)
immunoglobulin heavy constant mu
chr15_+_81071708 1.754 NM_018689
KIAA1199
KIAA1199
chr17_-_18528844 1.712 CCDC144B
coiled-coil domain containing 144B (pseudogene)
chr14_-_107199126 1.666 IGHG3
immunoglobulin heavy constant gamma 3 (G3m marker)
chr1_-_36565849 1.661 NM_005202
COL8A2
collagen, type VIII, alpha 2
chr14_-_106994001 1.657 IGHV3-48
IGH@
IGHA1
IGHM
immunoglobulin heavy variable 3-48
immunoglobulin heavy locus
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant mu
chr7_-_100171269 1.626 NM_001168682
SAP25
Sin3A-associated protein, 25kDa
chr2_-_87035518 1.585 NM_001145873
CD8A
CD8a molecule
chr4_+_102711833 1.574 BANK1
B-cell scaffold protein with ankyrin repeats 1
chr12_-_56583244 1.522 SMARCC2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2
chr11_-_66103874 1.516 NM_004292
RIN1
Ras and Rab interactor 1
chr12_+_49208615 1.504 CACNB3
calcium channel, voltage-dependent, beta 3 subunit
chr11_+_67034164 1.502 ADRBK1
adrenergic, beta, receptor kinase 1
chr14_-_107013122 1.456 IGHV4-31
IGHG1
immunoglobulin heavy variable 4-31
immunoglobulin heavy constant gamma 1 (G1m marker)
chr6_+_138188352 1.454 NM_006290
TNFAIP3
tumor necrosis factor, alpha-induced protein 3
chr14_-_107211131 1.405 IGHG1
immunoglobulin heavy constant gamma 1 (G1m marker)
chr9_+_138594030 1.389 NM_020822
KCNT1
potassium channel, subfamily T, member 1
chr10_+_104154228 1.371 NM_001077493
NM_001077494
NFKB2

nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)

chr16_+_67679011 1.365 NM_001013838
RLTPR
RGD motif, leucine rich repeats, tropomodulin domain and proline-rich containing
chr11_+_67034148 1.361 ADRBK1
adrenergic, beta, receptor kinase 1
chr19_-_49149252 1.353 NM_001217
CA11
carbonic anhydrase XI
chr1_-_202129731 1.334 PTPN7
protein tyrosine phosphatase, non-receptor type 7
chr19_+_35634153 1.329 NM_022006
FXYD7
FXYD domain containing ion transport regulator 7
chr6_-_30043547 1.321 NM_170769
NM_025236
RNF39

ring finger protein 39

chr1_+_248100492 1.294 NM_175911
OR2L13
olfactory receptor, family 2, subfamily L, member 13
chr17_+_16593571 1.291 NM_014695
CCDC144B
CCDC144A
coiled-coil domain containing 144B (pseudogene)
coiled-coil domain containing 144A
chr1_+_151129104 1.289 NM_001204848
NM_024575
TNFAIP8L2-SCNM1
TNFAIP8L2
TNFAIP8L2-SCNM1 readthrough
tumor necrosis factor, alpha-induced protein 8-like 2
chr11_+_67033929 1.246 ADRBK1
adrenergic, beta, receptor kinase 1
chr17_+_45810609 1.240 NM_013351
TBX21
T-box 21
chr6_-_41673677 1.232 TFEB
transcription factor EB
chr19_+_49977817 1.228 NM_001204503
FLT3LG
fms-related tyrosine kinase 3 ligand
chr11_-_64511550 1.221 NM_001098671
RASGRP2
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr14_-_106829736 1.196 IGHA1
IGHD
IGHG3
IGHM
SKAP2
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant delta
immunoglobulin heavy constant gamma 3 (G3m marker)
immunoglobulin heavy constant mu
src kinase associated phosphoprotein 2
chr19_-_47734215 1.176 NM_014417
BBC3
BCL2 binding component 3
chr11_+_67033889 1.162 NM_001619
ADRBK1
adrenergic, beta, receptor kinase 1
chrX_-_71497052 1.157 RPS4X
ribosomal protein S4, X-linked
chr16_-_15950850 1.153 NM_001040113
NM_001040114
NM_002474
NM_022844
MYH11



myosin, heavy chain 11, smooth muscle



chr14_-_106725232 1.143 ZCWPW2
IGHV3-23
IGKV3-20
IGK@
zinc finger, CW type with PWWP domain 2
immunoglobulin heavy variable 3-23
immunoglobulin kappa variable 3-20
immunoglobulin kappa locus
chr16_-_2390593 1.142 ABCA3
ATP-binding cassette, sub-family A (ABC1), member 3
chr5_-_146833150 1.132 NM_001387
DPYSL3
dihydropyrimidinase-like 3
chr2_-_75426613 1.124 NM_001058
NM_015727
TACR1

tachykinin receptor 1

chr16_-_2390737 1.123 NM_001089
ABCA3
ATP-binding cassette, sub-family A (ABC1), member 3
chrX_-_71497079 1.108 NM_001007
RPS4X
ribosomal protein S4, X-linked
chr17_-_40833840 1.102 NM_016602
CCR10
chemokine (C-C motif) receptor 10
chr9_-_117160748 1.101 AKNA
AT-hook transcription factor
chr16_+_31484497 1.091 NM_015927
TGFB1I1
transforming growth factor beta 1 induced transcript 1
chr6_+_35436177 1.068 NM_007104
RPL10A
ribosomal protein L10a
chr11_+_60691911 1.055 NM_017870
NM_178031
TMEM132A

transmembrane protein 132A

chr6_+_35436196 1.050 RPL10A
ribosomal protein L10a
chr14_-_96180402 1.047 NM_001098725
NM_021966
TCL1A

T-cell leukemia/lymphoma 1A

chr17_+_1958354 1.043 NM_006497
HIC1
hypermethylated in cancer 1
chr16_+_71392615 1.030 NM_001740
NM_007088
CALB2

calbindin 2

chr9_-_136024522 1.023 NM_001042368
RALGDS
ral guanine nucleotide dissociation stimulator
chr19_-_2051222 1.023 NM_017572
NM_199054
MKNK2

MAP kinase interacting serine/threonine kinase 2

chr22_+_23412727 1.022 GNAZ
guanine nucleotide binding protein (G protein), alpha z polypeptide
chr12_+_49208214 1.005 NM_001206917
CACNB3
calcium channel, voltage-dependent, beta 3 subunit
chr11_+_46368881 0.996 NM_001199266
NM_001199267
NM_001199268
NM_003646
DGKZ



diacylglycerol kinase, zeta



chr16_-_2390711 0.972 ABCA3
ATP-binding cassette, sub-family A (ABC1), member 3
chr22_+_23412364 0.970 NM_002073
GNAZ
guanine nucleotide binding protein (G protein), alpha z polypeptide
chr20_-_46415277 0.966 NM_001161841
NM_198596
SULF2

sulfatase 2

chr1_+_93297532 0.954 NM_000969
RPL5
ribosomal protein L5
chr12_-_120638894 0.939 RPLP0
ribosomal protein, large, P0
chr12_+_7033625 0.934 NM_001007026
ATN1
atrophin 1
chr15_-_38856830 0.931 NM_001128602
NM_005739
RASGRP1

RAS guanyl releasing protein 1 (calcium and DAG-regulated)

chr1_+_17248425 0.930 NM_014675
CROCC
ciliary rootlet coiled-coil, rootletin
chr16_-_69788798 0.929 NM_014062
NOB1
NIN1/RPN12 binding protein 1 homolog (S. cerevisiae)
chr14_+_31343642 0.924 NM_001135058
NM_004086
COCH

coagulation factor C homolog, cochlin (Limulus polyphemus)

chr6_+_151186884 0.914 MTHFD1L
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like
chr12_+_58120029 0.904 LOC100130776
uncharacterized LOC100130776
chr15_-_83209185 0.897 NM_001199057
NM_001021
RPS17L
RPS17
ribosomal protein S17-like
ribosomal protein S17
chr16_+_15737123 0.888 NM_001143979
NDE1
nudE nuclear distribution gene E homolog 1 (A. nidulans)
chr12_-_120638909 0.885 RPLP0
ribosomal protein, large, P0
chr10_-_79789164 0.872 POLR3A
polymerase (RNA) III (DNA directed) polypeptide A, 155kDa
chr12_-_56583301 0.850 NM_001130420
NM_003075
NM_139067
SMARCC2


SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2


chr18_+_14179298 0.849 ANKRD20A5P
ankyrin repeat domain 20 family, member A5, pseudogene
chr22_+_22676814 0.848


chr19_-_19754369 0.844 GMIP
GEM interacting protein
chr14_+_52118539 0.843 NM_152330
FRMD6
FERM domain containing 6
chr17_-_9862765 0.833 NM_003644
GAS7
growth arrest-specific 7
chr10_-_30024594 0.826 NM_003174
SVIL
supervillin
chr1_+_223900328 0.825 CAPN2
calpain 2, (m/II) large subunit
chr19_-_19754452 0.815 NM_016573
GMIP
GEM interacting protein
chr17_-_33469269 0.815 NM_001014445
NM_018096
NLE1

notchless homolog 1 (Drosophila)

chr9_-_139622599 0.814 SNORA43
SNHG7
small nucleolar RNA, H/ACA box 43
small nucleolar RNA host gene 7 (non-protein coding)
chr17_+_7591666 0.813 NM_001143992
NM_018081
WRAP53

WD repeat containing, antisense to TP53

chr7_+_148959219 0.809 NM_001195220
ZNF783
zinc finger family member 783
chr9_-_134615216 0.807 RAPGEF1
Rap guanine nucleotide exchange factor (GEF) 1
chr19_+_54041332 0.805 NM_001079906
NM_001253798
NM_001253799
ZNF331


zinc finger protein 331


chr16_+_71392637 0.799 CALB2
calbindin 2
chr1_+_93297598 0.798 RPL5
ribosomal protein L5
chr1_+_93297614 0.794 RPL5
ribosomal protein L5
chr22_+_19705990 0.785 SEPT5-GP1BB
SEPT5-GP1BB readthrough
chr1_-_17766142 0.780 RCC2
regulator of chromosome condensation 2
chr8_+_17434700 0.778 PDGFRL
platelet-derived growth factor receptor-like
chr17_+_19912608 0.776 NM_001243439
SPECC1
sperm antigen with calponin homology and coiled-coil domains 1
chr11_+_125034604 0.767 PKNOX2
PBX/knotted 1 homeobox 2
chr14_-_75078669 0.762 NM_000428
LTBP2
latent transforming growth factor beta binding protein 2
chr15_+_101390032 0.761 LOC145757
uncharacterized LOC145757
chr16_+_69345250 0.751 NM_013245
VPS4A
vacuolar protein sorting 4 homolog A (S. cerevisiae)
chr2_+_234263153 0.744 DGKD
diacylglycerol kinase, delta 130kDa
chr2_-_136875629 0.743 NM_003467
CXCR4
chemokine (C-X-C motif) receptor 4
chr19_-_1650246 0.739 NM_001136139
TCF3
transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)
chr15_+_68117940 0.734 NM_001031807
SKOR1
SKI family transcriptional corepressor 1
chr12_-_120638912 0.732 NM_001002
NM_053275
RPLP0

ribosomal protein, large, P0

chr19_-_19051899 0.725 HOMER3
homer homolog 3 (Drosophila)
chr10_+_103892786 0.719 NM_015062
PPRC1
peroxisome proliferator-activated receptor gamma, coactivator-related 1
chr10_+_6244839 0.717 NM_004566
PFKFB3
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
chr17_+_72199794 0.717 NM_000999
NM_001035258
RPL38

ribosomal protein L38

chr7_+_148844440 0.709 NM_170686
ZNF398
zinc finger protein 398
chr2_+_11273178 0.709 NM_182500
C2orf50
chromosome 2 open reading frame 50
chr3_-_52029860 0.709 RPL29
ribosomal protein L29
chr3_+_5164032 0.705 ARL8B
ADP-ribosylation factor-like 8B
chr22_-_22307212 0.699 NM_014634
PPM1F
protein phosphatase, Mg2+/Mn2+ dependent, 1F
chr2_+_234263141 0.698 NM_152879
DGKD
diacylglycerol kinase, delta 130kDa
chr19_-_19052032 0.697 NM_004838
HOMER3
homer homolog 3 (Drosophila)
chr3_-_52029907 0.692 RPL29
ribosomal protein L29
chr17_+_16318848 0.690 NM_016113
TRPV2
transient receptor potential cation channel, subfamily V, member 2
chr1_+_109642814 0.677 SCARNA2
small Cajal body-specific RNA 2
chr22_-_50682915 0.677 TUBGCP6
tubulin, gamma complex associated protein 6
chr10_-_79789290 0.677 NM_007055
POLR3A
polymerase (RNA) III (DNA directed) polypeptide A, 155kDa
chr6_-_33547833 0.676 BAK1
BCL2-antagonist/killer 1
chr11_+_8008866 0.676 NM_003754
EIF3F
eukaryotic translation initiation factor 3, subunit F
chr17_-_8868931 0.673 NM_001142633
NM_001251851
NM_001251852
NM_001251853
NM_001251855
PIK3R5




phosphoinositide-3-kinase, regulatory subunit 5




chr19_+_39903749 0.662 NM_022835
PLEKHG2
pleckstrin homology domain containing, family G (with RhoGef domain) member 2
chr19_+_53073515 0.659 NM_018260
ZNF701
zinc finger protein 701
chr6_+_151187064 0.659 MTHFD1L
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like
chr4_-_24981769 0.654 NM_173463
CCDC149
coiled-coil domain containing 149
chr12_-_120703488 0.651 PXN
paxillin
chr7_-_92747317 0.651 NM_001193307
NM_017654
SAMD9

sterile alpha motif domain containing 9

chr17_+_63133501 0.649 RGS9
regulator of G-protein signaling 9
chr4_-_2010702 0.646 WHSC2
Wolf-Hirschhorn syndrome candidate 2
chr6_+_151186814 0.644 NM_001242767
NM_001242769
NM_015440
MTHFD1L


methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like


chr17_-_43209681 0.642 NM_133373
PLCD3
phospholipase C, delta 3
chr21_+_42741983 0.642 MX2
myxovirus (influenza virus) resistance 2 (mouse)
chr3_-_52029957 0.642 NM_000992
RPL29
ribosomal protein L29
chr1_+_36348816 0.642 EIF2C1
eukaryotic translation initiation factor 2C, 1
chr17_+_16318911 0.640 TRPV2
transient receptor potential cation channel, subfamily V, member 2
chr17_+_62075710 0.639 NM_001164257
NM_001191029
NM_001191030
NM_001191031
C17orf72



chromosome 17 open reading frame 72



chr11_-_71524890 0.632 LOC285407
asparagine-linked glycosylation 1 homolog pseudogene
chr16_+_30406711 0.632 NM_152652
ZNF48
zinc finger protein 48
chr19_+_1941184 0.632 CSNK1G2
casein kinase 1, gamma 2
chr7_-_27183225 0.631 NM_019102
HOXA5
homeobox A5
chr8_-_146012653 0.624 NM_030580
ZNF34
zinc finger protein 34
chr17_+_72199841 0.622 RPL38
ribosomal protein L38
chr1_+_28844762 0.619 RCC1
regulator of chromosome condensation 1
chr6_-_41703345 0.615 TFEB
transcription factor EB
chr17_-_16395479 0.615 NM_001113567
NM_207387
FAM211A

family with sequence similarity 211, member A

chr6_+_87647023 0.614 NM_000865
HTR1E
5-hydroxytryptamine (serotonin) receptor 1E
chrX_+_47053271 0.610 UBA1
ubiquitin-like modifier activating enzyme 1
chr7_+_75831194 0.610 NM_001110199
SRRM3
serine/arginine repetitive matrix 3
chr14_-_107218786 0.606 IGHA1
IGHG1
IGHM
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant mu
chr19_+_1941157 0.603 NM_001319
CSNK1G2
casein kinase 1, gamma 2
chr1_-_156675237 0.601 NM_001878
NM_001199723
CRABP2

cellular retinoic acid binding protein 2

chr15_-_22473092 0.600


chr15_-_40599872 0.600 PLCB2
phospholipase C, beta 2
chr1_+_203830732 0.599 NM_003094
SNRPE
small nuclear ribonucleoprotein polypeptide E
chr10_-_15761655 0.599 NM_003638
ITGA8
integrin, alpha 8
chr12_-_120703549 0.595 NM_001080855
NM_001243756
NM_002859
PXN


paxillin


chr3_+_38035614 0.595 VILL
villin-like
chr4_-_120548329 0.593 NM_033430
PDE5A
phosphodiesterase 5A, cGMP-specific
chr1_-_17766241 0.591 NM_018715
RCC2
regulator of chromosome condensation 2
chr9_+_131183122 0.587 CERCAM
cerebral endothelial cell adhesion molecule
chr5_-_180670874 0.587 NM_006098
GNB2L1
guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1
chr2_-_166060552 0.586 NM_001081676
NM_001081677
NM_006922
SCN3A


sodium channel, voltage-gated, type III, alpha subunit


chr22_-_50682793 0.583 TUBGCP6
tubulin, gamma complex associated protein 6
chr1_+_159175048 0.583 NM_001122951
DARC
Duffy blood group, chemokine receptor
chr22_-_31503484 0.581 NM_080430
SELM
selenoprotein M
chr11_+_125034558 0.580 NM_022062
PKNOX2
PBX/knotted 1 homeobox 2
chr7_-_38389424 0.580


chr22_+_19705891 0.578 NM_001009939
SEPT5
septin 5
chr19_+_33793743 0.577 LOC80054
uncharacterized LOC80054
chr6_-_32920812 0.575 NM_006120
HLA-DMA
major histocompatibility complex, class II, DM alpha
chr19_-_1848359 0.575 REXO1
REX1, RNA exonuclease 1 homolog (S. cerevisiae)
chr11_-_117102758 0.567 PCSK7
proprotein convertase subtilisin/kexin type 7
chr2_-_158184145 0.567 NM_001009959
ERMN
ermin, ERM-like protein
chr8_-_102217868 0.565 NM_001042511
ZNF706
zinc finger protein 706
chr7_-_38389575 0.564 TRGV5
T cell receptor gamma variable 5
chr19_-_33793441 0.563 CEBPA
CCAAT/enhancer binding protein (C/EBP), alpha
chr1_+_37940180 0.563 ZC3H12A
zinc finger CCCH-type containing 12A
chr15_-_75194542 0.563 C15orf17
chromosome 15 open reading frame 17
chr2_-_154335181 0.558 NM_019845
RPRM
reprimo, TP53 dependent G2 arrest mediator candidate
chr3_-_183543295 0.557 NM_024871
MAP6D1
MAP6 domain containing 1
chr18_-_21166440 0.557 NM_000271
NPC1
Niemann-Pick disease, type C1
chr11_-_64510461 0.556 RASGRP2
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr7_-_22539795 0.555 NM_001164460
NM_207342
STEAP1B

STEAP family member 1B

chr8_+_67341244 0.554 NM_015169
RRS1
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
chr22_+_31608280 0.553 LIMK2
LIM domain kinase 2
chr12_+_110338064 0.546 NM_001143852
TCHP
trichoplein, keratin filament binding
chrX_+_47053302 0.541 UBA1
ubiquitin-like modifier activating enzyme 1
chr22_+_31608145 0.539 LIMK2
LIM domain kinase 2
chr17_-_8286444 0.532 NM_000987
RPL26
ribosomal protein L26

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
5.07 8.30e-06 GO:0002376 immune system process
6.22 7.85e-05 GO:0006955 immune response
1.84 1.91e-02 GO:0050896 response to stimulus

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
4.62 2.95e-03 GO:0005624 membrane fraction
4.47 3.88e-03 GO:0005626 insoluble fraction
3.75 7.65e-03 GO:0000267 cell fraction

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
70.38 1.07e-11 GO:0003823 antigen binding