Motif ID: CUACAGU

Z-value: 1.087


Mature miRNA associated with seed CUACAGU:

NamemiRBase Accession
hsa-miR-139-5p MIMAT0000250



Activity profile for motif CUACAGU.

activity profile for motif CUACAGU


Sorted Z-values histogram for motif CUACAGU

Sorted Z-values for motif CUACAGU



Network of associatons between targets according to the STRING database.



First level regulatory network of CUACAGU

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chrX_-_25034064 2.549 NM_139058
ARX
aristaless related homeobox
chr16_+_58534045 2.414 NM_001242833
NM_001242834
NM_001242835
NM_001242836
NDRG4



NDRG family member 4



chr9_-_101470836 2.403 NM_005458
GABBR2
gamma-aminobutyric acid (GABA) B receptor, 2
chr16_+_58498725 2.250 NM_022910
NDRG4
NDRG family member 4
chr16_+_58497993 2.101 NM_001130487
NDRG4
NDRG family member 4
chr5_+_6448735 1.906 NM_001145161
UBE2QL1
ubiquitin-conjugating enzyme E2Q family-like 1
chr6_-_46047978 1.896 NM_001114086
CLIC5
chloride intracellular channel 5
chrX_-_142723921 1.846 NM_001184749
SLITRK4
SLIT and NTRK-like family, member 4
chr16_+_58497548 1.818 NM_020465
NDRG4
NDRG family member 4
chr2_+_27070962 1.765 NM_020134
NM_001253723
NM_001253724
DPYSL5


dihydropyrimidinase-like 5


chrX_-_142722318 1.744 NM_001184750
SLITRK4
SLIT and NTRK-like family, member 4
chr5_-_136834887 1.725 NM_004598
SPOCK1
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
chr6_-_45983279 1.502 NM_016929
CLIC5
chloride intracellular channel 5
chr1_+_167064086 1.456 NM_001080426
DUSP27
dual specificity phosphatase 27 (putative)
chrX_+_105412297 1.437 NM_001171020
NM_152423
MUM1L1

melanoma associated antigen (mutated) 1-like 1

chr12_-_117799410 1.357 NM_000620
NM_001204218
NOS1

nitric oxide synthase 1 (neuronal)

chrX_-_114468604 1.349 NM_001243963
NM_020871
LRCH2

leucine-rich repeats and calponin homology (CH) domain containing 2

chr11_-_118047336 1.334 NM_004588
SCN2B
sodium channel, voltage-gated, type II, beta
chr1_+_237205701 1.304 NM_001035
RYR2
ryanodine receptor 2 (cardiac)
chr7_+_154002194 1.298 NM_001936
DPP6
dipeptidyl-peptidase 6
chr12_-_117747214 1.284 NM_001204214
NOS1
nitric oxide synthase 1 (neuronal)
chr10_-_99393175 1.263 NM_178832
MORN4
MORN repeat containing 4
chr1_-_72748147 1.237 NM_173808
NEGR1
neuronal growth regulator 1
chr3_+_120627026 1.234 NM_014980
STXBP5L
syntaxin binding protein 5-like
chr16_+_76343734 1.220 NM_138994
CNTNAP4
contactin associated protein-like 4
chr4_+_113739203 1.207 NM_001127493
ANK2
ankyrin 2, neuronal
chr3_-_69171536 1.198 NM_198271
LMOD3
leiomodin 3 (fetal)
chr4_-_168155576 1.196 NM_001204353
SPOCK3
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
chr7_+_153749740 1.154 NM_130797
DPP6
dipeptidyl-peptidase 6
chr8_+_91803777 1.150 NM_022351
NECAB1
N-terminal EF-hand calcium binding protein 1
chr5_-_160975124 1.147 NM_000813
NM_021911
GABRB2

gamma-aminobutyric acid (GABA) A receptor, beta 2

chr5_+_126626455 1.143 NM_032446
MEGF10
multiple EGF-like-domains 10
chr7_+_153584383 1.141 NM_001039350
DPP6
dipeptidyl-peptidase 6
chr1_-_183387501 1.127 NM_015039
NMNAT2
nicotinamide nucleotide adenylyltransferase 2
chr16_-_46782104 1.125 NM_182493
MYLK3
myosin light chain kinase 3
chr6_+_84743250 1.118 NM_138409
MRAP2
melanocortin 2 receptor accessory protein 2
chr16_-_4292052 1.104 NM_001098814
SRL
sarcalumenin
chr7_+_31092067 1.093 NM_001118
NM_001199635
NM_001199636
NM_001199637
ADCYAP1R1



adenylate cyclase activating polypeptide 1 (pituitary) receptor type I



chrX_-_142722869 1.085 NM_173078
SLITRK4
SLIT and NTRK-like family, member 4
chr10_+_119301955 1.085 NM_001165924
NM_004098
EMX2

empty spiracles homeobox 2

chr12_-_117742856 1.075 NM_001204213
NOS1
nitric oxide synthase 1 (neuronal)
chr7_+_140774031 1.074 NM_001195278
LOC100507421
transmembrane protein 178-like
chr4_-_168155732 1.073 NM_001040159
NM_001204352
NM_001204354
NM_001204355
NM_001204356
NM_001204358
NM_001251967
NM_016950
SPOCK3







sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3







chr6_-_127840499 1.065 NM_001012279
C6orf174
chromosome 6 open reading frame 174
chr6_-_127780534 1.039 NM_014702
KIAA0408
KIAA0408
chr10_+_134000335 1.037 NM_006426
DPYSL4
dihydropyrimidinase-like 4
chr14_+_67999915 1.036 NM_020715
PLEKHH1
pleckstrin homology domain containing, family H (with MyTH4 domain) member 1
chr6_-_53530505 1.024 NM_001003760
KLHL31
kelch-like 31 (Drosophila)
chr1_+_57110745 1.005 NM_006252
PRKAA2
protein kinase, AMP-activated, alpha 2 catalytic subunit
chr2_+_210288668 0.990 NM_001039538
MAP2
microtubule-associated protein 2
chr3_-_116164363 0.987 NM_002338
LSAMP
limbic system-associated membrane protein
chr4_+_186064416 0.982 NM_001151
SLC25A4
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4
chrX_-_8700170 0.970 NM_000216
KAL1
Kallmann syndrome 1 sequence
chr3_+_158991035 0.969 NM_001197107
NM_001197108
NM_014575
SCHIP1


schwannomin interacting protein 1


chr11_-_118016134 0.969 NM_001142349
SCN4B
sodium channel, voltage-gated, type IV, beta
chr6_-_105584982 0.966 NM_001199563
BVES
blood vessel epicardial substance
chr1_+_203096835 0.956 NM_000674
NM_001048230
ADORA1

adenosine A1 receptor

chr4_-_65275000 0.954 NM_001010874
TECRL
trans-2,3-enoyl-CoA reductase-like
chr6_-_105584542 0.941 NM_007073
BVES
blood vessel epicardial substance
chr6_+_101846860 0.933 NM_001166247
NM_021956
NM_175768
GRIK2


glutamate receptor, ionotropic, kainate 2


chr3_-_179754516 0.930 NM_016559
PEX5L
peroxisomal biogenesis factor 5-like
chr18_+_11751470 0.919 NM_001142339
NM_002071
GNAL

guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type

chr3_+_159557649 0.919 NM_001197109
SCHIP1
schwannomin interacting protein 1
chr13_+_39261172 0.912 NM_207361
FREM2
FRAS1 related extracellular matrix protein 2
chr5_-_58334936 0.905 NM_001197221
NM_001197222
PDE4D

phosphodiesterase 4D, cAMP-specific

chr4_+_113970784 0.893 NM_001148
NM_020977
ANK2

ankyrin 2, neuronal

chr16_+_18995255 0.883 NM_024847
TMC7
transmembrane channel-like 7
chr2_-_172750724 0.882 NM_003705
SLC25A12
solute carrier family 25 (mitochondrial carrier, Aralar), member 12
chr5_-_58571916 0.880 NM_001197220
PDE4D
phosphodiesterase 4D, cAMP-specific
chr10_-_99393851 0.874 NM_001098831
MORN4
MORN repeat containing 4
chr17_-_41985112 0.872 NM_005374
MPP2
membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)
chr6_-_105584220 0.861 NM_147147
BVES
blood vessel epicardial substance
chr19_+_10541334 0.859 NM_001111308
PDE4A
phosphodiesterase 4A, cAMP-specific
chr5_-_45696219 0.854 NM_021072
HCN1
hyperpolarization activated cyclic nucleotide-gated potassium channel 1
chr11_-_118023534 0.851 NM_001142348
NM_174934
SCN4B

sodium channel, voltage-gated, type IV, beta

chr12_+_125811161 0.844 NM_052907
TMEM132B
transmembrane protein 132B
chr18_+_49866541 0.842 NM_005215
DCC
deleted in colorectal carcinoma
chr18_+_55816546 0.838 NM_001144965
NM_001144968
NM_001144969
NM_001144971
NEDD4L



neural precursor cell expressed, developmentally down-regulated 4-like



chr2_+_73144603 0.836 NM_004097
EMX1
empty spiracles homeobox 1
chr1_-_145039631 0.835 NM_001198832
PDE4DIP
phosphodiesterase 4D interacting protein
chr1_-_216896640 0.834 NM_001243515
NM_001243518
NM_001243519
NM_001438
ESRRG



estrogen-related receptor gamma



chr1_+_2985730 0.833 NM_022114
NM_199454
PRDM16

PR domain containing 16

chr12_+_26348268 0.830 NM_001135823
SSPN
sarcospan (Kras oncogene-associated gene)
chr18_+_11689135 0.826 NM_182978
GNAL
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type
chr2_+_210444364 0.824 NM_002374
NM_031845
NM_031847
MAP2


microtubule-associated protein 2


chr6_+_118869441 0.820 NM_002667
PLN
phospholamban
chr6_-_109762373 0.818 NM_001111298
NM_173672
PPIL6

peptidylprolyl isomerase (cyclophilin)-like 6

chr17_+_18128868 0.815 NM_004140
LLGL1
lethal giant larvae homolog 1 (Drosophila)
chr7_+_20370724 0.809 NM_002214
ITGB8
integrin, beta 8
chr2_+_220325533 0.805 NM_001173476
SPEG
SPEG complex locus
chr22_+_42372763 0.800 NM_019106
NM_145733
SEPT3

septin 3

chr19_+_16830786 0.789 NM_001007525
NWD1
NACHT and WD repeat domain containing 1
chr1_-_183274008 0.789 NM_170706
NMNAT2
nicotinamide nucleotide adenylyltransferase 2
chr7_+_94539209 0.778 NM_001166161
NM_001166162
NM_001166163
PPP1R9A


protein phosphatase 1, regulatory subunit 9A


chr5_+_31799030 0.774 NM_178140
PDZD2
PDZ domain containing 2
chr2_+_166326156 0.768 NM_001172173
CSRNP3
cysteine-serine-rich nuclear protein 3
chr3_+_42695175 0.767 NM_145166
ZBTB47
zinc finger and BTB domain containing 47
chr5_+_139175385 0.763 NM_032289
PSD2
pleckstrin and Sec7 domain containing 2
chr1_+_171810611 0.762 NM_001136127
NM_015569
DNM3

dynamin 3

chr22_-_33402648 0.760 NM_003490
NM_133633
SYN3

synapsin III

chr3_+_135684463 0.758 NM_001190447
NM_002718
PPP2R3A

protein phosphatase 2, regulatory subunit B'', alpha

chr3_+_32148000 0.757 NM_015141
GPD1L
glycerol-3-phosphate dehydrogenase 1-like
chr12_+_5153084 0.750 NM_002234
KCNA5
potassium voltage-gated channel, shaker-related subfamily, member 5
chrX_-_43832920 0.748 NM_000266
NDP
Norrie disease (pseudoglioma)
chr12_+_26348488 0.746 NM_005086
SSPN
sarcospan (Kras oncogene-associated gene)
chrX_+_37208527 0.745 NM_000950
NM_001142395
NM_001173486
NM_001173489
NM_001173490
PRRG1




proline rich Gla (G-carboxyglutamic acid) 1




chr5_+_161274196 0.732 NM_000806
GABRA1
gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr17_+_42733744 0.728 NM_001145080
C17orf104
chromosome 17 open reading frame 104
chr18_+_55862577 0.724 NM_001144970
NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like
chr6_-_137366100 0.721 NM_014432
IL20RA
interleukin 20 receptor, alpha
chr2_-_166930130 0.717 NM_001165963
NM_001165964
NM_006920
SCN1A


sodium channel, voltage-gated, type I, alpha subunit


chr8_+_35092963 0.715 NM_080872
UNC5D
unc-5 homolog D (C. elegans)
chr6_+_146348781 0.715 NM_000838
NM_001114329
GRM1

glutamate receptor, metabotropic 1

chr9_-_23821842 0.714 NM_001171195
ELAVL2
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chr7_-_83270746 0.710 NM_001178129
SEMA3E
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
chr9_-_23821477 0.707 NM_001171197
ELAVL2
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chr18_-_40857245 0.703 NM_020783
SYT4
synaptotagmin IV
chr1_-_217262946 0.700 NM_001243506
NM_206594
NM_206595
ESRRG


estrogen-related receptor gamma


chr8_-_17555158 0.698 NM_020749
MTUS1
microtubule associated tumor suppressor 1
chr5_-_132073143 0.689 NM_007054
KIF3A
kinesin family member 3A
chr6_-_90121966 0.688 NM_021244
RRAGD
Ras-related GTP binding D
chr20_-_9819406 0.684 NM_020341
NM_177990
PAK7

p21 protein (Cdc42/Rac)-activated kinase 7

chr5_-_138775213 0.684 NM_152686
DNAJC18
DnaJ (Hsp40) homolog, subfamily C, member 18
chr3_+_135741576 0.683 NM_181897
PPP2R3A
protein phosphatase 2, regulatory subunit B'', alpha
chr15_-_40545109 0.678 NM_001039905
C15orf56
chromosome 15 open reading frame 56
chr16_+_25703346 0.677 NM_006040
HS3ST4
heparan sulfate (glucosamine) 3-O-sulfotransferase 4
chr20_+_44650260 0.676 NM_001134771
SLC12A5
solute carrier family 12 (potassium/chloride transporter), member 5
chr5_-_58652671 0.674 NM_001197219
PDE4D
phosphodiesterase 4D, cAMP-specific
chr1_+_42846427 0.663 NM_173642
RIMKLA
ribosomal modification protein rimK-like family member A
chr5_+_161277702 0.663 NM_001127648
GABRA1
gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr10_+_73723992 0.656 NM_004273
CHST3
carbohydrate (chondroitin 6) sulfotransferase 3
chr5_+_161275541 0.652 NM_001127645
GABRA1
gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr1_-_217311095 0.651 NM_001134285
ESRRG
estrogen-related receptor gamma
chr6_-_46138584 0.647 NM_021572
ENPP5
ectonucleotide pyrophosphatase/phosphodiesterase 5 (putative)
chr16_+_18995508 0.646 NM_001160364
TMC7
transmembrane channel-like 7
chr7_-_107880492 0.643 NM_001037132
NRCAM
neuronal cell adhesion molecule
chr8_+_21900389 0.643 NM_003867
FGF17
fibroblast growth factor 17
chrX_-_92928566 0.643 NM_004538
NAP1L3
nucleosome assembly protein 1-like 3
chr2_+_149632772 0.639 NM_004522
KIF5C
kinesin family member 5C
chr13_+_51796363 0.639 NM_001242312
NM_145019
FAM124A

family with sequence similarity 124A

chr5_-_59064437 0.632 NM_001197218
PDE4D
phosphodiesterase 4D, cAMP-specific
chr15_+_79575145 0.626 NM_001146341
ANKRD34C
ankyrin repeat domain 34C
chr17_+_11144739 0.624 NM_001173461
NM_001173462
NM_207386
SHISA6


shisa homolog 6 (Xenopus laevis)


chr16_+_29823408 0.618 NM_145239
PRRT2
proline-rich transmembrane protein 2
chr14_-_103989195 0.616 NM_001823
CKB
creatine kinase, brain
chr18_+_55711388 0.612 NM_001144967
NM_001243960
NM_015277
NEDD4L


neural precursor cell expressed, developmentally down-regulated 4-like


chr7_+_94536926 0.612 NM_001166160
NM_017650
PPP1R9A

protein phosphatase 1, regulatory subunit 9A

chr9_-_93405066 0.609 NM_017594
DIRAS2
DIRAS family, GTP-binding RAS-like 2
chr9_-_91793681 0.608 NM_016848
SHC3
SHC (Src homology 2 domain containing) transforming protein 3
chrX_-_15402469 0.606 NM_004469
FIGF
c-fos induced growth factor (vascular endothelial growth factor D)
chr12_+_70172748 0.606 NM_001024647
RAB3IP
RAB3A interacting protein (rabin3)
chr16_-_755718 0.605 NM_153350
FBXL16
F-box and leucine-rich repeat protein 16
chr1_+_70225857 0.596 NM_020794
LRRC7
leucine rich repeat containing 7
chr1_-_214724974 0.592 NM_005401
PTPN14
protein tyrosine phosphatase, non-receptor type 14
chr3_+_141043054 0.590 NM_001080412
ZBTB38
zinc finger and BTB domain containing 38
chr5_+_161277391 0.590 NM_001127647
GABRA1
gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr1_+_205538111 0.583 NM_181644
MFSD4
major facilitator superfamily domain containing 4
chr1_+_110082493 0.579 NM_031936
GPR61
G protein-coupled receptor 61
chr12_-_48119224 0.576 NM_001172439
NM_001172440
NM_006025
ENDOU


endonuclease, polyU-specific


chr10_+_52834233 0.575 NM_006258
PRKG1
protein kinase, cGMP-dependent, type I
chr8_+_58906968 0.573 NM_147189
FAM110B
family with sequence similarity 110, member B
chrX_-_77041678 0.573 NM_000489
NM_138270
ATRX

alpha thalassemia/mental retardation syndrome X-linked

chr16_+_76311175 0.571 NM_033401
CNTNAP4
contactin associated protein-like 4
chrX_+_105066531 0.568 NM_198465
NRK
Nik related kinase
chr18_-_12656730 0.563 NM_001128627
SPIRE1
spire homolog 1 (Drosophila)
chr19_+_10563581 0.557 NM_006202
PDE4A
phosphodiesterase 4A, cAMP-specific
chr4_-_139163222 0.555 NM_014331
SLC7A11
solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
chr1_+_155829259 0.550 NM_152280
SYT11
synaptotagmin XI
chr5_+_161275897 0.550 NM_001127646
GABRA1
gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr13_-_37494370 0.548 NM_001127217
NM_005905
SMAD9

SMAD family member 9

chr16_-_10276610 0.548 NM_000833
GRIN2A
glutamate receptor, ionotropic, N-methyl D-aspartate 2A
chr2_-_217560247 0.546 NM_000599
IGFBP5
insulin-like growth factor binding protein 5
chr7_-_108096693 0.543 NM_001193582
NM_001193583
NM_001193584
NM_005010
NRCAM



neuronal cell adhesion molecule



chr2_+_220408742 0.540 NM_001005209
TMEM198
transmembrane protein 198
chr8_-_133459508 0.538 NM_001204824
KCNQ3
potassium voltage-gated channel, KQT-like subfamily, member 3
chr8_-_81787015 0.535 NM_001033723
ZNF704
zinc finger protein 704
chr1_-_154164551 0.532 NM_152263
TPM3
tropomyosin 3
chr1_+_29562947 0.531 NM_001195001
NM_005704
NM_133177
NM_133178
PTPRU



protein tyrosine phosphatase, receptor type, U



chr7_-_79082870 0.531 NM_012301
MAGI2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr8_-_105601234 0.527 NM_001135703
NM_013437
LRP12

low density lipoprotein receptor-related protein 12

chr5_+_161274684 0.525 NM_001127643
GABRA1
gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr18_-_12657911 0.523 NM_001128626
NM_020148
SPIRE1

spire homolog 1 (Drosophila)

chr3_+_138066489 0.522 NM_001252091
NM_012219
MRAS

muscle RAS oncogene homolog

chr3_+_179370779 0.518 NM_003940
USP13
ubiquitin specific peptidase 13 (isopeptidase T-3)
chr2_+_170683900 0.516 NM_172070
UBR3
ubiquitin protein ligase E3 component n-recognin 3 (putative)
chr12_-_110505499 0.513 NM_207435
C12orf76
chromosome 12 open reading frame 76
chr1_-_85155885 0.508 NM_001166295
NM_001166417
NM_001166293
NM_001166294
NM_014021
SSX2IP




synovial sarcoma, X breakpoint 2 interacting protein




chr15_-_79383080 0.508 NM_001145648
NM_002891
RASGRF1

Ras protein-specific guanine nucleotide-releasing factor 1

chr3_-_184870727 0.506 NM_001025266
C3orf70
chromosome 3 open reading frame 70
chr15_-_65360297 0.505 NM_016563
RASL12
RAS-like, family 12
chr10_-_7661613 0.505 NM_032817
ITIH5
inter-alpha-trypsin inhibitor heavy chain family, member 5
chr15_-_48470453 0.504 NM_016132
MYEF2
myelin expression factor 2
chr11_+_66025070 0.502 NM_001134776
NM_001134774
NM_022822
KLC2


kinesin light chain 2


chr4_+_646965 0.499 NM_001145292
PDE6B
phosphodiesterase 6B, cGMP-specific, rod, beta
chr20_-_23402038 0.497 NM_022080
NAPB
N-ethylmaleimide-sensitive factor attachment protein, beta
chrX_-_63005212 0.497 NM_001173479
ARHGEF9
Cdc42 guanine nucleotide exchange factor (GEF) 9
chr11_+_35684342 0.496 NM_017583
TRIM44
tripartite motif containing 44
chr1_-_225840660 0.492 NM_001008493
NM_018212
ENAH

enabled homolog (Drosophila)

chr7_+_94285676 0.491 NM_001172437
NM_001172438
PEG10

paternally expressed 10

chr1_+_220701547 0.491 NM_018650
MARK1
MAP/microtubule affinity-regulating kinase 1

Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Nothing significant found in function category.