Motif ID: CUX2.p2

Z-value: 1.579


Transcription factors associated with CUX2.p2:

Gene SymbolEntrez IDGene Name
CUX2 23316 cut-like homeobox 2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
CUX2hg19_v1_chr12_+_111471827_1114719170.154.2e-01Click!


Activity profile for motif CUX2.p2.

activity profile for motif CUX2.p2


Sorted Z-values histogram for motif CUX2.p2

Sorted Z-values for motif CUX2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of CUX2.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 153 entries
PromoterScoreRefseqGene SymbolGene Name
chr3_+_52811601 11.488 NM_002215
 ITIH1
inter-alpha-trypsin inhibitor heavy chain 1
chr1_+_57320442 11.203 NM_000562
 C8A
complement component 8, alpha polypeptide
chr1_-_159684274 10.959 NM_000567
 CRP
C-reactive protein, pentraxin-related
chr4_-_72649734 9.635 NM_000583
 GC
group-specific component (vitamin D binding protein)
chr7_-_100239136 9.549 NM_003227
 TFR2
transferrin receptor 2
chr19_-_58864820 8.349 NM_130786
 A1BG
alpha-1-B glycoprotein
chr1_-_157811491 8.290 NM_005894
 CD5L
CD5 molecule-like
chr1_+_198608216 8.288 PTPRC
protein tyrosine phosphatase, receptor type, C
chr1_+_198608244 7.571 PTPRC
protein tyrosine phosphatase, receptor type, C
chr1_+_198608136 7.353 NM_002838
NM_080921
NM_080923
 PTPRC


protein tyrosine phosphatase, receptor type, C


chr2_-_89165652 6.681


chrX_+_123480131 5.864 NM_001114937
NM_002351
 SH2D1A

SH2 domain containing 1A

chr3_-_170744458 5.573 SLC2A2
solute carrier family 2 (facilitated glucose transporter), member 2
chr13_-_46756291 5.287 LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr7_-_36764000 5.183 NM_001177506
NM_001177507
NM_001637
 AOAH


acyloxyacyl hydrolase (neutrophil)


chr14_+_88490893 4.873 LOC283587
uncharacterized LOC283587
chr17_-_64225496 4.546 NM_000042
 APOH
apolipoprotein H (beta-2-glycoprotein I)
chr13_-_46756295 4.287 LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr1_+_206730456 4.016 NM_182665
 RASSF5
Ras association (RalGDS/AF-6) domain family member 5
chr3_-_170744529 3.911 SLC2A2
solute carrier family 2 (facilitated glucose transporter), member 2

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 16 of 16 entries
Enrichment   P-value GO Accession GO Term
211.11 8.64e-03 GO:0031639 plasminogen activation
27.71 3.25e-03 GO:0072376 protein activation cascade
14.89 5.08e-03 GO:0002252 immune effector process
12.02 1.42e-02 GO:0002696 positive regulation of leukocyte activation
11.82 1.54e-02 GO:0050867 positive regulation of cell activation
10.22 3.06e-02 GO:0051249 regulation of lymphocyte activation
9.94 3.50e-02 GO:0002253 activation of immune response
9.37 9.62e-03 GO:0050778 positive regulation of immune response
9.34 8.32e-05 GO:0002684 positive regulation of immune system process
9.28 4.81e-02 GO:0002694 regulation of leukocyte activation
8.22 1.07e-03 GO:0050776 regulation of immune response
6.72 3.44e-04 GO:0002682 regulation of immune system process
5.24 9.47e-03 GO:0048584 positive regulation of response to stimulus
5.17 1.05e-02 GO:0006952 defense response
4.19 8.62e-03 GO:0002376 immune system process
3.54 3.66e-03 GO:0048583 regulation of response to stimulus

Gene overrepresentation in compartment category:

Showing 1 to 2 of 2 entries
Enrichment   P-value GO Accession GO Term
60.34 2.87e-02 GO:0042613 MHC class II protein complex
3.12 3.37e-03 GO:0005576 extracellular region

Gene overrepresentation in function category:

Showing 1 to 9 of 9 entries
Enrichment   P-value GO Accession GO Term
168.90 2.52e-03 GO:0051637 Gram-positive bacterial cell surface binding
105.57 7.02e-03 GO:0032395 MHC class II receptor activity
52.80 2.97e-02 GO:0051635 bacterial cell surface binding
49.69 3.37e-02 GO:0043499 eukaryotic cell surface binding
42.24 4.68e-02 GO:0030169 low-density lipoprotein particle binding
38.40 1.52e-04 GO:0043498 cell surface binding
3.50 1.62e-03 GO:0004872 receptor activity
3.09 3.03e-03 GO:0004871 signal transducer activity
3.09 3.03e-03 GO:0060089 molecular transducer activity