Motif ID: EBF1.p2

Z-value: 1.571


Transcription factors associated with EBF1.p2:

Gene SymbolEntrez IDGene Name
EBF1 1879 early B-cell factor 1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
EBF1hg19_v1_chr5_-_158526698_1585267870.383.0e-02Click!


Activity profile for motif EBF1.p2.

activity profile for motif EBF1.p2


Sorted Z-values histogram for motif EBF1.p2

Sorted Z-values for motif EBF1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of EBF1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr22_+_23229959 5.522 NM_001178126
IGLL5
IGLC1
immunoglobulin lambda-like polypeptide 5
immunoglobulin lambda constant 1 (Mcg marker)
chr9_-_136344182 2.553 NM_001145099
NM_017585
SLC2A6

solute carrier family 2 (facilitated glucose transporter), member 6

chr3_+_186560478 2.388 ADIPOQ
adiponectin, C1Q and collagen domain containing
chr19_-_51327003 2.376 NM_002257
KLK1
kallikrein 1
chr14_-_106478129 2.305 IGHV4-31
IGHD
IGHG3
IGHM
immunoglobulin heavy variable 4-31
immunoglobulin heavy constant delta
immunoglobulin heavy constant gamma 3 (G3m marker)
immunoglobulin heavy constant mu
chr14_-_106780535 2.301 IGHA1
IGHA2
IGHD
IGHG1
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant alpha 2 (A2m marker)
immunoglobulin heavy constant delta
immunoglobulin heavy constant gamma 1 (G1m marker)
chr16_+_89696775 2.152 DPEP1
dipeptidase 1 (renal)
chr10_-_81320141 2.102 NM_001098668
SFTPA1
SFTPA2
surfactant protein A1
surfactant protein A2
chr19_+_42381189 2.094 NM_001783
NM_021601
CD79A

CD79a molecule, immunoglobulin-associated alpha

chr10_+_81370694 2.094 NM_001093770
NM_001164644
NM_001164645
NM_001164646
NM_001164647
NM_005411
SFTPA1





surfactant protein A1





chr2_-_85895863 1.972 NM_000542
NM_198843
SFTPB

surfactant protein B

chr3_+_186560462 1.953 NM_001177800
NM_004797
ADIPOQ

adiponectin, C1Q and collagen domain containing

chr14_-_106791054 1.949 IGHV4-31
IGHV3-30
IGHA1
IGHD
IGHG1
IGHG2
IGHG3
IGHM
SCFV
immunoglobulin heavy variable 4-31
immunoglobulin heavy variable 3-30
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant delta
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant gamma 2 (G2m marker)
immunoglobulin heavy constant gamma 3 (G3m marker)
immunoglobulin heavy constant mu
single-chain Fv fragment
chr22_-_37545944 1.771 NM_000878
IL2RB
interleukin 2 receptor, beta
chr22_+_22550159 1.766 IGLV6-57
immunoglobulin lambda variable 6-57
chr14_-_106994001 1.762 IGHV3-48
IGH@
IGHA1
IGHM
immunoglobulin heavy variable 3-48
immunoglobulin heavy locus
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant mu
chr7_+_128577990 1.714 NM_001098629
NM_001098630
NM_001242452
IRF5


interferon regulatory factor 5


chr14_-_107013122 1.700 IGHV4-31
IGHG1
immunoglobulin heavy variable 4-31
immunoglobulin heavy constant gamma 1 (G1m marker)
chr14_-_107199126 1.689 IGHG3
immunoglobulin heavy constant gamma 3 (G3m marker)
chr14_-_107048697 1.659 IGHG1
immunoglobulin heavy constant gamma 1 (G1m marker)
chr14_-_106877689 1.621 IGHV4-31
IGH@
IGHA1
IGHA2
IGHG1
IGHG4
IGHM
immunoglobulin heavy variable 4-31
immunoglobulin heavy locus
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant alpha 2 (A2m marker)
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant gamma 4 (G4m marker)
immunoglobulin heavy constant mu
chr1_-_108507474 1.589 NM_006113
VAV3
vav 3 guanine nucleotide exchange factor
chr19_-_2308155 1.568 NM_001101391
LINGO3
leucine rich repeat and Ig domain containing 3
chr1_+_207627614 1.522 NM_001006658
NM_001877
CR2

complement component (3d/Epstein Barr virus) receptor 2

chr17_-_38721701 1.506 NM_001838
CCR7
chemokine (C-C motif) receptor 7
chr1_+_32716839 1.500 NM_005356
LCK
lymphocyte-specific protein tyrosine kinase
chr7_+_128578246 1.499 NM_032643
IRF5
interferon regulatory factor 5
chr5_+_3596167 1.469 NM_024337
IRX1
iroquois homeobox 1
chr14_-_107259620 1.462 IGHV5-78
immunoglobulin heavy variable 5-78 (pseudogene)
chr6_-_32551993 1.444 HLA-DRB1
HLA-DRB4
HLA-DRB5
major histocompatibility complex, class II, DR beta 1
major histocompatibility complex, class II, DR beta 4
major histocompatibility complex, class II, DR beta 5
chr1_-_202130677 1.407 NM_001199797
NM_002832
PTPN7

protein tyrosine phosphatase, non-receptor type 7

chr10_-_73848766 1.372 NM_001134434
NM_014767
SPOCK2

sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2

chr16_+_776957 1.357 NM_032304
HAGHL
hydroxyacylglutathione hydrolase-like
chr8_-_119964059 1.357 NM_002546
TNFRSF11B
tumor necrosis factor receptor superfamily, member 11b
chr10_+_70587293 1.354 NM_001130159
NM_001130160
NM_001130161
NM_152709
STOX1



storkhead box 1



chr14_-_106691698 1.333


chr16_+_56899118 1.332 NM_000339
NM_001126107
NM_001126108
SLC12A3


solute carrier family 12 (sodium/chloride transporters), member 3


chr19_-_55836668 1.328 NM_001085488
TMEM150B
transmembrane protein 150B
chr11_-_67205151 1.323 NM_005608
PTPRCAP
protein tyrosine phosphatase, receptor type, C-associated protein
chr17_+_73584138 1.317 MYO15B
myosin XVB pseudogene
chr10_-_73848530 1.295 NM_001244950
SPOCK2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
chr11_-_101454658 1.270 NM_004621
TRPC6
transient receptor potential cation channel, subfamily C, member 6
chr16_+_89696674 1.239 DPEP1
dipeptidase 1 (renal)
chr15_+_41136178 1.237 NM_003710
NM_181642
SPINT1

serine peptidase inhibitor, Kunitz type 1

chr10_-_73848263 1.224 SPOCK2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
chr8_-_11324184 1.221 NM_053279
FAM167A
family with sequence similarity 167, member A
chr4_+_42399855 1.201 NM_001080505
SHISA3
shisa homolog 3 (Xenopus laevis)
chr8_+_142138684 1.194 NM_014957
DENND3
DENN/MADD domain containing 3
chr15_-_22473092 1.193


chr10_-_73848278 1.176 SPOCK2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
chr7_+_26331493 1.171 NM_001199835
NM_013322
SNX10

sorting nexin 10

chr16_+_22825481 1.162 HS3ST2
heparan sulfate (glucosamine) 3-O-sulfotransferase 2
chr10_-_73848309 1.126 SPOCK2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
chr15_-_63673918 1.116 CA12
carbonic anhydrase XII
chr20_-_62284701 1.106 NM_015894
STMN3
stathmin-like 3
chr17_+_76126835 1.101 NM_152468
TMC8
transmembrane channel-like 8
chr6_-_132722564 1.096 NM_015529
MOXD1
monooxygenase, DBH-like 1
chr6_-_32731266 1.091 NM_001198858
HLA-DQB2
major histocompatibility complex, class II, DQ beta 2
chr17_-_16875388 1.091 NM_012452
TNFRSF13B
tumor necrosis factor receptor superfamily, member 13B
chr22_+_37309618 1.077 NM_000395
CSF2RB
colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
chr2_-_182521732 1.076 NM_001030311
NM_001030312
NM_001030313
NM_001160277
NM_201548
CERKL




ceramide kinase-like




chr22_+_22723972 1.071


chr7_+_102074002 1.069 ORAI2
ORAI calcium release-activated calcium modulator 2
chr11_+_62037629 1.065 NM_002411
SCGB2A2
secretoglobin, family 2A, member 2
chr4_+_4861371 1.050 NM_002448
MSX1
msh homeobox 1
chr6_-_32634287 1.036 NM_001243961
NM_002123
HLA-DQB1

major histocompatibility complex, class II, DQ beta 1

chr22_+_37257004 1.033 NM_000631
NM_013416
NCF4

neutrophil cytosolic factor 4, 40kDa

chr7_-_100171269 1.028 NM_001168682
SAP25
Sin3A-associated protein, 25kDa
chr15_-_63674074 1.026 NM_001218
NM_206925
CA12

carbonic anhydrase XII

chr1_-_202129731 1.026 PTPN7
protein tyrosine phosphatase, non-receptor type 7
chr16_+_68679198 1.016 CDH3
cadherin 3, type 1, P-cadherin (placental)
chr14_-_106926393 1.015 IGHA1
IGHG1
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
chr17_+_59529778 1.013 TBX4
T-box 4
chr8_-_33424642 1.013 NM_024787
RNF122
ring finger protein 122
chr1_-_1051458 1.013 C1orf159
chromosome 1 open reading frame 159
chr14_+_61788398 1.006 NM_006255
PRKCH
protein kinase C, eta
chr7_-_150329285 0.997 GIMAP6
GTPase, IMAP family member 6
chr7_-_150329735 0.988 NM_001244071
NM_001244072
NM_024711
GIMAP6


GTPase, IMAP family member 6


chr1_-_115632047 0.980 NM_005725
TSPAN2
tetraspanin 2
chr19_+_7702020 0.979 STXBP2
syntaxin binding protein 2
chr11_+_111808017 0.974 DIXDC1
DIX domain containing 1
chr4_+_2819888 0.965 NM_001145856
SH3BP2
SH3-domain binding protein 2
chr17_-_56409868 0.963


chr16_+_23194037 0.956 NM_001039
SCNN1G
sodium channel, nonvoltage-gated 1, gamma
chr16_+_23313590 0.955 NM_000336
SCNN1B
sodium channel, nonvoltage-gated 1, beta
chr16_+_68679229 0.955 CDH3
cadherin 3, type 1, P-cadherin (placental)
chr11_+_46403302 0.953 NM_001012333
MDK
midkine (neurite growth-promoting factor 2)
chr19_+_47813074 0.949 NM_001736
C5AR1
complement component 5a receptor 1
chr1_+_27668499 0.943 SYTL1
synaptotagmin-like 1
chr2_-_242800989 0.917 NM_005018
PDCD1
programmed cell death 1
chrX_+_128913881 0.914 NM_018990
SASH3
SAM and SH3 domain containing 3
chr5_-_180018465 0.911 NM_052863
SCGB3A1
secretoglobin, family 3A, member 1
chrX_-_119445306 0.911 NM_001104544
NM_001104545
NM_017938
FAM70A


family with sequence similarity 70, member A


chr4_+_2813966 0.910 SH3BP2
SH3-domain binding protein 2
chr8_-_38326115 0.904 FGFR1
fibroblast growth factor receptor 1
chr11_-_128737132 0.903 NM_153764
NM_153765
NM_153766
NM_153767
KCNJ1



potassium inwardly-rectifying channel, subfamily J, member 1



chr16_+_3115641 0.902 NM_001012632
NM_001012636
IL32

interleukin 32

chr15_-_79237353 0.900 NM_004390
CTSH
cathepsin H
chr11_+_827584 0.898 NM_173584
EFCAB4A
EF-hand calcium binding domain 4A
chr15_-_38856830 0.894 NM_001128602
NM_005739
RASGRP1

RAS guanyl releasing protein 1 (calcium and DAG-regulated)

chr5_+_133450353 0.882 NM_003202
TCF7
transcription factor 7 (T-cell specific, HMG-box)
chr7_+_102073953 0.880 NM_001126340
NM_032831
ORAI2

ORAI calcium release-activated calcium modulator 2

chr15_-_79237320 0.879 CTSH
cathepsin H
chr11_+_60223281 0.871 NM_021950
NM_152866
MS4A1

membrane-spanning 4-domains, subfamily A, member 1

chr9_-_137809710 0.871 NM_002003
FCN1
ficolin (collagen/fibrinogen domain containing) 1
chr13_+_111154013 0.863 COL4A2
collagen, type IV, alpha 2
chrX_+_128913897 0.856 SASH3
SAM and SH3 domain containing 3
chr16_+_1290677 0.851 NM_003294
TPSB2
TPSAB1
tryptase beta 2 (gene/pseudogene)
tryptase alpha/beta 1
chr5_-_100238870 0.850 NM_175052
NM_005668
ST8SIA4

ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4

chr14_-_107034760 0.850 IGHG1
immunoglobulin heavy constant gamma 1 (G1m marker)
chr4_+_2794712 0.850 NM_001122681
SH3BP2
SH3-domain binding protein 2
chrX_-_153881757 0.849 NM_020994
NM_172377
CTAG2

cancer/testis antigen 2

chr9_-_117150217 0.836 AKNA
AT-hook transcription factor
chr1_+_27668462 0.836 NM_001193308
NM_032872
SYTL1

synaptotagmin-like 1

chr21_-_43816123 0.835 NM_024022
NM_032405
TMPRSS3

transmembrane protease, serine 3

chr6_+_1390068 0.830 NM_001452
FOXF2
forkhead box F2
chr9_+_139221931 0.828 NM_001145638
NM_015597
GPSM1

G-protein signaling modulator 1

chr16_+_1306272 0.820 NM_012217
TPSD1
tryptase delta 1
chr16_+_22825806 0.819 NM_006043
HS3ST2
heparan sulfate (glucosamine) 3-O-sulfotransferase 2
chr6_-_31550065 0.819 NM_002341
NM_009588
LTB

lymphotoxin beta (TNF superfamily, member 3)

chr4_-_90758126 0.818 NM_001146054
NM_007308
NM_000345
SNCA


synuclein, alpha (non A4 component of amyloid precursor)


chr22_+_45098091 0.817 NM_181334
PRR5-ARHGAP8
PRR5
PRR5-ARHGAP8 readthrough
proline rich 5 (renal)
chr16_+_215972 0.809 NM_001003938
HBM
hemoglobin, mu
chr5_-_141257943 0.805 NM_002587
NM_032420
PCDH1

protocadherin 1

chr14_-_105531739 0.799 NM_013345
GPR132
G protein-coupled receptor 132
chr17_-_8815799 0.796 NM_014308
PIK3R5
phosphoinositide-3-kinase, regulatory subunit 5
chr15_+_81293286 0.795 NM_022566
MESDC1
mesoderm development candidate 1
chr20_+_39969420 0.794 NM_022896
LPIN3
lipin 3
chr22_-_43116796 0.794 NM_017436
A4GALT
alpha 1,4-galactosyltransferase
chr2_-_31361591 0.792 NM_001253826
NM_024572
GALNT14

UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 14 (GalNAc-T14)

chr7_+_26331611 0.791 SNX10
sorting nexin 10
chr22_-_30662787 0.790 NM_020530
OSM
oncostatin M
chr7_+_30791744 0.786 NM_001199219
NM_006774
INMT-FAM188B
INMT

INMT-FAM188B readthrough (non-protein coding)
indolethylamine N-methyltransferase

chr5_+_148651443 0.784 AFAP1L1
actin filament associated protein 1-like 1
chr16_+_86544104 0.768 NM_001451
FOXF1
forkhead box F1
chr19_+_39903749 0.761 NM_022835
PLEKHG2
pleckstrin homology domain containing, family G (with RhoGef domain) member 2
chr12_-_51717835 0.757 BIN2
bridging integrator 2
chr14_+_73704204 0.756 NM_173462
PAPLN
papilin, proteoglycan-like sulfated glycoprotein
chr19_-_8642309 0.749 NM_012335
MYO1F
myosin IF
chr3_+_32433151 0.747 NM_138410
NM_181472
CMTM7

CKLF-like MARVEL transmembrane domain containing 7

chr15_-_44969085 0.746 NM_001145112
PATL2
protein associated with topoisomerase II homolog 2 (yeast)
chr22_+_45098046 0.745 NM_181333
PRR5
proline rich 5 (renal)
chr17_-_62009620 0.744 NM_000626
NM_001039933
NM_021602
CD79B


CD79b molecule, immunoglobulin-associated beta


chr12_-_108991783 0.742 TMEM119
transmembrane protein 119
chr10_-_14646237 0.741 FAM107B
family with sequence similarity 107, member B
chr8_-_6735438 0.741 NM_005218
DEFB1
defensin, beta 1
chr6_-_167275657 0.738 NM_001006932
RPS6KA2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr12_-_108991893 0.737 NM_181724
TMEM119
transmembrane protein 119
chr5_+_80256457 0.734 NM_006909
RASGRF2
Ras protein-specific guanine nucleotide-releasing factor 2
chr16_+_86544233 0.733 FOXF1
forkhead box F1
chr7_-_86688944 0.732 NM_001142749
KIAA1324L
KIAA1324-like
chr19_+_1026271 0.730 NM_004368
NM_201277
CNN2

calponin 2

chr2_-_110873638 0.719 MALL
mal, T-cell differentiation protein-like
chr5_+_31193852 0.718 CDH6
cadherin 6, type 2, K-cadherin (fetal kidney)
chr9_-_114937464 0.715 NM_022486
SUSD1
sushi domain containing 1
chr6_-_32151996 0.712 NM_001136
NM_001206929
NM_001206932
NM_001206934
NM_001206936
NM_001206940
NM_001206954
NM_001206966
NM_172197
AGER








advanced glycosylation end product-specific receptor








chr5_-_153825348 0.709 FLJ38109
uncharacterized LOC386627
chr1_-_168698412 0.705 NM_001937
DPT
dermatopontin
chr6_+_31691120 0.704 NM_025260
NM_138272
NM_138273
NM_138274
NM_138275
NM_138277
C6orf25





chromosome 6 open reading frame 25





chr5_+_80256557 0.692 RASGRF2
Ras protein-specific guanine nucleotide-releasing factor 2
chr15_-_90349819 0.691 ANPEP
alanyl (membrane) aminopeptidase
chr20_-_52790511 0.690 NM_000782
NM_001128915
CYP24A1

cytochrome P450, family 24, subfamily A, polypeptide 1

chr22_-_50968409 0.688 TYMP
thymidine phosphorylase
chr3_-_50360109 0.683 NM_003773
NM_033158
HYAL2

hyaluronoglucosaminidase 2

chr12_-_48152860 0.683 NM_001098531
RAPGEF3
Rap guanine nucleotide exchange factor (GEF) 3
chr9_+_140172273 0.679 NM_017723
C9orf167
chromosome 9 open reading frame 167
chr3_-_142607737 0.679 NM_013363
PCOLCE2
procollagen C-endopeptidase enhancer 2
chr7_+_89840999 0.677 NM_001244944
NM_001244945
NM_152999
NM_001040665
NM_001244946
STEAP2




STEAP family member 2, metalloreductase




chr19_-_14260728 0.676 LPHN1
latrophilin 1
chr3_+_154797644 0.675 NM_007287
MME
membrane metallo-endopeptidase
chr19_-_7812396 0.673 NM_001144893
NM_001144894
NM_001144895
NM_001144896
NM_001144897
NM_001144899
NM_021155
CD209






CD209 molecule






chr7_+_127881330 0.669 NM_000230
LEP
leptin
chr11_+_46403205 0.663 NM_002391
MDK
midkine (neurite growth-promoting factor 2)
chr8_-_144654921 0.662 NM_001100878
C8orf73
chromosome 8 open reading frame 73
chr5_+_148651395 0.659 NM_001146337
NM_152406
AFAP1L1

actin filament associated protein 1-like 1

chr12_-_108991843 0.659 TMEM119
transmembrane protein 119
chr19_-_53400812 0.657 ZNF320
zinc finger protein 320
chr3_-_69435429 0.657 NM_015123
FRMD4B
FERM domain containing 4B
chr22_-_46933066 0.655 NM_014246
CELSR1
cadherin, EGF LAG seven-pass G-type receptor 1 (flamingo homolog, Drosophila)
chr22_-_43117270 0.651 A4GALT
alpha 1,4-galactosyltransferase
chr16_+_4385141 0.649 GLIS2
GLIS family zinc finger 2
chr16_-_3184858 0.649


chr5_-_149792276 0.649 CD74
CD74 molecule, major histocompatibility complex, class II invariant chain
chr21_+_44073650 0.647 NM_001001567
NM_001001568
NM_001001569
NM_001001570
NM_001001571
NM_001001572
NM_001001573
NM_001001574
NM_001001575
NM_001001576
NM_001001577
NM_001001578
NM_001001579
NM_001001580
NM_001001581
NM_001001582
NM_001001583
NM_001001584
NM_001001585
NM_002606
PDE9A



















phosphodiesterase 9A



















chr7_+_139528951 0.646 NM_001061
NM_001166253
NM_030984
TBXAS1


thromboxane A synthase 1 (platelet)


chr6_+_36973409 0.636 NM_173558
FGD2
FYVE, RhoGEF and PH domain containing 2
chr12_-_48152180 0.636 NM_001098532
NM_006105
RAPGEF3

Rap guanine nucleotide exchange factor (GEF) 3

chr19_+_12305869 0.635


chr19_-_51487070 0.633 NM_139277
NM_001207053
NM_001243126
NM_005046
KLK7



kallikrein-related peptidase 7



chr16_+_28943259 0.630 NM_001178098
NM_001770
CD19

CD19 molecule

chr11_-_85430382 0.627 NM_001162952
NM_206930
SYTL2

synaptotagmin-like 2

chr12_-_108991832 0.626 TMEM119
transmembrane protein 119
chr22_+_37678519 0.623 CYTH4
cytohesin 4
chr2_+_228678556 0.623 NM_001130046
NM_004591
CCL20

chemokine (C-C motif) ligand 20

chr1_+_901876 0.620 NM_001160184
NM_032129
PLEKHN1

pleckstrin homology domain containing, family N member 1

chr4_+_2043719 0.620 NM_001168243
NM_001141936
C4orf48

chromosome 4 open reading frame 48

chr2_-_169103886 0.620 NM_013233
STK39
serine threonine kinase 39
chr17_-_37381920 0.619 NM_198993
STAC2
SH3 and cysteine rich domain 2
chr7_-_93519990 0.619 NM_006528
TFPI2
tissue factor pathway inhibitor 2
chr17_-_73874634 0.619 NM_033452
TRIM47
tripartite motif containing 47

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
5.24 3.71e-08 GO:0002376 immune system process
6.93 5.03e-08 GO:0006955 immune response
21.94 9.42e-07 GO:0002429 immune response-activating cell surface receptor signaling pathway
21.11 1.29e-06 GO:0002768 immune response-regulating cell surface receptor signaling pathway
20.85 1.42e-05 GO:0050851 antigen receptor-mediated signaling pathway
11.71 2.24e-05 GO:0002253 activation of immune response
12.97 5.90e-05 GO:0002757 immune response-activating signal transduction
12.67 7.05e-05 GO:0002764 immune response-regulating signaling pathway
65.15 1.24e-04 GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II
9.21 1.73e-04 GO:0050778 positive regulation of immune response
58.30 2.01e-04 GO:0050853 B cell receptor signaling pathway
25.18 5.48e-04 GO:0019882 antigen processing and presentation
30.78 2.92e-03 GO:0007585 respiratory gaseous exchange
9.38 3.19e-03 GO:0051249 regulation of lymphocyte activation
4.84 4.58e-03 GO:0002682 regulation of immune system process
6.12 4.92e-03 GO:0002684 positive regulation of immune system process
6.06 5.32e-03 GO:0050776 regulation of immune response
8.52 5.98e-03 GO:0002694 regulation of leukocyte activation
8.19 7.68e-03 GO:0050865 regulation of cell activation
10.14 9.43e-03 GO:0051251 positive regulation of lymphocyte activation
9.45 1.40e-02 GO:0002696 positive regulation of leukocyte activation
9.30 1.54e-02 GO:0050867 positive regulation of cell activation
9.04 1.80e-02 GO:0019221 cytokine-mediated signaling pathway
6.86 2.37e-02 GO:0034097 response to cytokine stimulus
17.88 2.58e-02 GO:0031294 lymphocyte costimulation
17.88 2.58e-02 GO:0031295 T cell costimulation
17.88 2.58e-02 GO:0060333 interferon-gamma-mediated signaling pathway
8.16 3.18e-02 GO:0071345 cellular response to cytokine stimulus
16.30 3.71e-02 GO:0071346 cellular response to interferon-gamma

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
79.11 1.13e-05 GO:0042613 MHC class II protein complex
34.62 3.85e-04 GO:0042611 MHC protein complex
184.57 2.94e-03 GO:0019814 immunoglobulin complex
184.57 2.94e-03 GO:0019815 B cell receptor complex

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
69.23 7.55e-15 GO:0003823 antigen binding