Motif ID: EBF1.p2

Z-value: 1.571


Transcription factors associated with EBF1.p2:

Gene SymbolEntrez IDGene Name
EBF1 1879 early B-cell factor 1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
EBF1hg19_v1_chr5_-_158526698_1585267870.383.0e-02Click!


Activity profile for motif EBF1.p2.

activity profile for motif EBF1.p2


Sorted Z-values histogram for motif EBF1.p2

Sorted Z-values for motif EBF1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of EBF1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr22_+_23229959 5.522 NM_001178126
 IGLL5
IGLC1
immunoglobulin lambda-like polypeptide 5
immunoglobulin lambda constant 1 (Mcg marker)
chr9_-_136344182 2.553 NM_001145099
NM_017585
 SLC2A6

solute carrier family 2 (facilitated glucose transporter), member 6

chr3_+_186560478 2.388 ADIPOQ
adiponectin, C1Q and collagen domain containing
chr19_-_51327003 2.376 NM_002257
 KLK1
kallikrein 1
chr14_-_106478129 2.305 IGHV4-31
IGHD
IGHG3
IGHM
immunoglobulin heavy variable 4-31
immunoglobulin heavy constant delta
immunoglobulin heavy constant gamma 3 (G3m marker)
immunoglobulin heavy constant mu
chr14_-_106780535 2.301 IGHA1
IGHA2
IGHD
IGHG1
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant alpha 2 (A2m marker)
immunoglobulin heavy constant delta
immunoglobulin heavy constant gamma 1 (G1m marker)
chr16_+_89696775 2.152 DPEP1
dipeptidase 1 (renal)
chr10_-_81320141 2.102 NM_001098668
 SFTPA1
SFTPA2
surfactant protein A1
surfactant protein A2
chr19_+_42381189 2.094 NM_001783
NM_021601
 CD79A

CD79a molecule, immunoglobulin-associated alpha

chr10_+_81370694 2.094 NM_001093770
NM_001164644
NM_001164645
NM_001164646
NM_001164647
NM_005411
 SFTPA1





surfactant protein A1





chr2_-_85895863 1.972 NM_000542
NM_198843
 SFTPB

surfactant protein B

chr3_+_186560462 1.953 NM_001177800
NM_004797
 ADIPOQ

adiponectin, C1Q and collagen domain containing

chr14_-_106791054 1.949 IGHV4-31
IGHV3-30
IGHA1
IGHD
IGHG1
IGHG2
IGHG3
IGHM
SCFV
immunoglobulin heavy variable 4-31
immunoglobulin heavy variable 3-30
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant delta
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant gamma 2 (G2m marker)
immunoglobulin heavy constant gamma 3 (G3m marker)
immunoglobulin heavy constant mu
single-chain Fv fragment
chr22_-_37545944 1.771 NM_000878
 IL2RB
interleukin 2 receptor, beta
chr22_+_22550159 1.766 IGLV6-57
immunoglobulin lambda variable 6-57
chr14_-_106994001 1.762 IGHV3-48
IGH@
IGHA1
IGHM
immunoglobulin heavy variable 3-48
immunoglobulin heavy locus
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant mu
chr7_+_128577990 1.714 NM_001098629
NM_001098630
NM_001242452
 IRF5


interferon regulatory factor 5


chr14_-_107013122 1.700 IGHV4-31
IGHG1
immunoglobulin heavy variable 4-31
immunoglobulin heavy constant gamma 1 (G1m marker)
chr14_-_107199126 1.689 IGHG3
immunoglobulin heavy constant gamma 3 (G3m marker)
chr14_-_107048697 1.659 IGHG1
immunoglobulin heavy constant gamma 1 (G1m marker)

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 29 entries
Enrichment   P-value GO Accession GO Term
65.15 1.24e-04 GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II
58.30 2.01e-04 GO:0050853 B cell receptor signaling pathway
30.78 2.92e-03 GO:0007585 respiratory gaseous exchange
25.18 5.48e-04 GO:0019882 antigen processing and presentation
21.94 9.42e-07 GO:0002429 immune response-activating cell surface receptor signaling pathway
21.11 1.29e-06 GO:0002768 immune response-regulating cell surface receptor signaling pathway
20.85 1.42e-05 GO:0050851 antigen receptor-mediated signaling pathway
17.88 2.58e-02 GO:0031294 lymphocyte costimulation
17.88 2.58e-02 GO:0031295 T cell costimulation
17.88 2.58e-02 GO:0060333 interferon-gamma-mediated signaling pathway
16.30 3.71e-02 GO:0071346 cellular response to interferon-gamma
12.97 5.90e-05 GO:0002757 immune response-activating signal transduction
12.67 7.05e-05 GO:0002764 immune response-regulating signaling pathway
11.71 2.24e-05 GO:0002253 activation of immune response
10.14 9.43e-03 GO:0051251 positive regulation of lymphocyte activation
9.45 1.40e-02 GO:0002696 positive regulation of leukocyte activation
9.38 3.19e-03 GO:0051249 regulation of lymphocyte activation
9.30 1.54e-02 GO:0050867 positive regulation of cell activation
9.21 1.73e-04 GO:0050778 positive regulation of immune response
9.04 1.80e-02 GO:0019221 cytokine-mediated signaling pathway

Gene overrepresentation in compartment category:

Showing 1 to 4 of 4 entries
Enrichment   P-value GO Accession GO Term
184.57 2.94e-03 GO:0019814 immunoglobulin complex
184.57 2.94e-03 GO:0019815 B cell receptor complex
79.11 1.13e-05 GO:0042613 MHC class II protein complex
34.62 3.85e-04 GO:0042611 MHC protein complex

Gene overrepresentation in function category:

Showing 1 to 1 of 1 entries
Enrichment   P-value GO Accession GO Term
69.23 7.55e-15 GO:0003823 antigen binding