Motif ID: ELF1,2,4.p2

Z-value: 2.824


Transcription factors associated with ELF1,2,4.p2:

Gene SymbolEntrez IDGene Name
ELF1 1997 E74-like factor 1 (ets domain transcription factor)
ELF2 1998 E74-like factor 2 (ets domain transcription factor)
ELF4 2000 E74-like factor 4 (ets domain transcription factor)

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
ELF1hg19_v1_chr13_-_41556188_415562040.631.2e-04Click!
ELF4hg19_v1_chrX_-_129244652_1292447230.476.5e-03Click!
ELF2hg19_v1_chr4_-_140060601_140060605-0.163.9e-01Click!


Activity profile for motif ELF1,2,4.p2.

activity profile for motif ELF1,2,4.p2


Sorted Z-values histogram for motif ELF1,2,4.p2

Sorted Z-values for motif ELF1,2,4.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ELF1,2,4.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_+_153330329 6.705 NM_002965
 S100A9
S100 calcium binding protein A9
chr19_+_3178735 6.530 NM_003775
 S1PR4
sphingosine-1-phosphate receptor 4
chr1_-_36948914 6.395 NM_000760
NM_156039
NM_172313
 CSF3R


colony stimulating factor 3 receptor (granulocyte)


chr1_-_36948423 6.366 CSF3R
colony stimulating factor 3 receptor (granulocyte)
chr10_-_72362513 6.355 NM_001083116
NM_005041
 PRF1

perforin 1 (pore forming protein)

chr10_-_72362441 5.998 PRF1
perforin 1 (pore forming protein)
chr1_-_161039413 5.750 ARHGAP30
Rho GTPase activating protein 30
chr19_-_51875790 5.604 NM_005601
 NKG7
natural killer cell group 7 sequence
chr1_-_156786500 5.575 NM_001161441
NM_001161442
NM_001161444
NM_003975
 SH2D2A



SH2 domain containing 2A



chr6_-_42419782 5.158 NM_033502
 TRERF1
transcriptional regulating factor 1
chr11_-_118123001 5.042 NM_198275
 MPZL3
myelin protein zero-like 3
chr11_+_118175294 4.927 NM_000733
 CD3E
CD3e molecule, epsilon (CD3-TCR complex)
chr5_+_137801166 4.790 EGR1
early growth response 1
chr1_-_161039649 4.699 ARHGAP30
Rho GTPase activating protein 30
chr15_+_81589240 4.662 NM_004513
 IL16
interleukin 16
chr5_+_137801178 4.588 NM_001964
 EGR1
early growth response 1
chr19_-_19754369 4.524 GMIP
GEM interacting protein
chr22_+_38035683 4.399 NM_018957
 SH3BP1
SH3-domain binding protein 1
chr4_-_153601085 4.369 NM_152680
 TMEM154
transmembrane protein 154
chr1_+_161185084 4.236 NM_004106
 FCER1G
Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 70 entries
Enrichment   P-value GO Accession GO Term
22.71 1.84e-02 GO:0010819 regulation of T cell chemotaxis
22.71 1.84e-02 GO:0010820 positive regulation of T cell chemotaxis
22.71 1.84e-02 GO:2000401 regulation of lymphocyte migration
22.71 1.84e-02 GO:2000403 positive regulation of lymphocyte migration
22.71 1.84e-02 GO:2000404 regulation of T cell migration
22.71 1.84e-02 GO:2000406 positive regulation of T cell migration
8.33 5.37e-06 GO:0030217 T cell differentiation
7.95 6.82e-07 GO:0050852 T cell receptor signaling pathway
7.69 2.21e-08 GO:0050851 antigen receptor-mediated signaling pathway
7.32 1.21e-09 GO:0042110 T cell activation
7.30 4.51e-03 GO:0042102 positive regulation of T cell proliferation
7.08 9.40e-08 GO:0002429 immune response-activating cell surface receptor signaling pathway
6.81 1.84e-07 GO:0002768 immune response-regulating cell surface receptor signaling pathway
6.69 2.59e-06 GO:0030098 lymphocyte differentiation
6.23 4.34e-12 GO:0046649 lymphocyte activation
5.77 3.33e-02 GO:0002831 regulation of response to biotic stimulus
5.76 1.19e-02 GO:0042129 regulation of T cell proliferation
5.53 5.19e-12 GO:0045321 leukocyte activation
5.52 1.76e-02 GO:0042113 B cell activation
5.45 2.06e-05 GO:0002521 leukocyte differentiation

Gene overrepresentation in compartment category:

Showing 1 to 9 of 9 entries
Enrichment   P-value GO Accession GO Term
23.18 1.02e-06 GO:0042101 T cell receptor complex
4.15 1.74e-03 GO:0043235 receptor complex
3.76 5.45e-03 GO:0045121 membrane raft
3.75 1.11e-02 GO:0009897 external side of plasma membrane
2.64 2.97e-02 GO:0015629 actin cytoskeleton
1.65 1.07e-03 GO:0005829 cytosol
1.26 1.87e-04 GO:0005737 cytoplasm
1.10 4.79e-05 GO:0044464 cell part
1.10 4.88e-05 GO:0005623 cell

Gene overrepresentation in function category:

Showing 1 to 11 of 11 entries
Enrichment   P-value GO Accession GO Term
12.55 1.60e-03 GO:0005164 tumor necrosis factor receptor binding
9.94 3.54e-02 GO:0001637 G-protein chemoattractant receptor activity
9.94 3.54e-02 GO:0004950 chemokine receptor activity
7.69 3.37e-02 GO:0032813 tumor necrosis factor receptor superfamily binding
4.79 1.04e-03 GO:0019955 cytokine binding
4.34 6.80e-03 GO:0017124 SH3 domain binding
2.87 2.07e-02 GO:0005096 GTPase activator activity
2.69 3.37e-04 GO:0030695 GTPase regulator activity
2.62 5.83e-04 GO:0060589 nucleoside-triphosphatase regulator activity
2.01 2.45e-03 GO:0030234 enzyme regulator activity
1.31 6.26e-05 GO:0005515 protein binding