Motif ID: ELF1,2,4.p2

Z-value: 2.824


Transcription factors associated with ELF1,2,4.p2:

Gene SymbolEntrez IDGene Name
ELF1 1997 E74-like factor 1 (ets domain transcription factor)
ELF2 1998 E74-like factor 2 (ets domain transcription factor)
ELF4 2000 E74-like factor 4 (ets domain transcription factor)

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
ELF1hg19_v1_chr13_-_41556188_415562040.631.2e-04Click!
ELF4hg19_v1_chrX_-_129244652_1292447230.476.5e-03Click!
ELF2hg19_v1_chr4_-_140060601_140060605-0.163.9e-01Click!


Activity profile for motif ELF1,2,4.p2.

activity profile for motif ELF1,2,4.p2


Sorted Z-values histogram for motif ELF1,2,4.p2

Sorted Z-values for motif ELF1,2,4.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ELF1,2,4.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_+_153330329 6.705 NM_002965
S100A9
S100 calcium binding protein A9
chr19_+_3178735 6.530 NM_003775
S1PR4
sphingosine-1-phosphate receptor 4
chr1_-_36948914 6.395 NM_000760
NM_156039
NM_172313
CSF3R


colony stimulating factor 3 receptor (granulocyte)


chr1_-_36948423 6.366 CSF3R
colony stimulating factor 3 receptor (granulocyte)
chr10_-_72362513 6.355 NM_001083116
NM_005041
PRF1

perforin 1 (pore forming protein)

chr10_-_72362441 5.998 PRF1
perforin 1 (pore forming protein)
chr1_-_161039413 5.750 ARHGAP30
Rho GTPase activating protein 30
chr19_-_51875790 5.604 NM_005601
NKG7
natural killer cell group 7 sequence
chr1_-_156786500 5.575 NM_001161441
NM_001161442
NM_001161444
NM_003975
SH2D2A



SH2 domain containing 2A



chr6_-_42419782 5.158 NM_033502
TRERF1
transcriptional regulating factor 1
chr11_-_118123001 5.042 NM_198275
MPZL3
myelin protein zero-like 3
chr11_+_118175294 4.927 NM_000733
CD3E
CD3e molecule, epsilon (CD3-TCR complex)
chr5_+_137801166 4.790 EGR1
early growth response 1
chr1_-_161039649 4.699 ARHGAP30
Rho GTPase activating protein 30
chr15_+_81589240 4.662 NM_004513
IL16
interleukin 16
chr5_+_137801178 4.588 NM_001964
EGR1
early growth response 1
chr19_-_19754369 4.524 GMIP
GEM interacting protein
chr22_+_38035683 4.399 NM_018957
SH3BP1
SH3-domain binding protein 1
chr4_-_153601085 4.369 NM_152680
TMEM154
transmembrane protein 154
chr1_+_161185084 4.236 NM_004106
FCER1G
Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide
chrX_-_70331297 4.202 NM_000206
IL2RG
interleukin 2 receptor, gamma
chr9_-_139927291 4.180 NM_004479
FUT7
fucosyltransferase 7 (alpha (1,3) fucosyltransferase)
chr1_-_161039586 4.171 ARHGAP30
Rho GTPase activating protein 30
chr1_+_161185061 4.119 FCER1G
Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide
chr22_+_38035694 4.101 SH3BP1
SH3-domain binding protein 1
chr3_-_183273407 4.097 NM_130446
KLHL6
kelch-like 6 (Drosophila)
chr3_+_186714335 4.011


chr2_+_98330030 4.004 NM_001079
ZAP70
zeta-chain (TCR) associated protein kinase 70kDa
chr19_-_19754452 4.000 NM_016573
GMIP
GEM interacting protein
chr16_-_50715116 3.803 SNX20
sorting nexin 20
chr5_+_176853673 3.760 NM_001004105
NM_001004106
NM_002082
GRK6


G protein-coupled receptor kinase 6


chr22_+_17565844 3.747 NM_014339
IL17RA
interleukin 17 receptor A
chr1_+_32716839 3.746 NM_005356
LCK
lymphocyte-specific protein tyrosine kinase
chr1_-_167487701 3.702 NM_000734
NM_198053
CD247

CD247 molecule

chr16_+_50308020 3.679 ADCY7
adenylate cyclase 7
chrX_-_77582979 3.612 NM_006639
CYSLTR1
cysteinyl leukotriene receptor 1
chr4_+_40198526 3.599 NM_004310
RHOH
ras homolog gene family, member H
chr22_+_17565920 3.531 IL17RA
interleukin 17 receptor A
chr20_-_33735060 3.519 NM_001145025
NM_018217
EDEM2

ER degradation enhancer, mannosidase alpha-like 2

chr22_+_38035718 3.513 SH3BP1
SH3-domain binding protein 1
chr11_-_64512925 3.511 NM_153819
RASGRP2
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr16_+_30194925 3.508 CORO1A
coronin, actin binding protein, 1A
chr14_+_75988765 3.485 NM_006399
BATF
basic leucine zipper transcription factor, ATF-like
chr7_+_50348255 3.482 IKZF1
IKAROS family zinc finger 1 (Ikaros)
chrX_+_135730335 3.479 NM_000074
CD40LG
CD40 ligand
chr7_+_143078395 3.475 ZYX
zyxin
chr16_-_3627353 3.411 NM_178844
NLRC3
NLR family, CARD domain containing 3
chr11_-_67169309 3.404 PPP1CA
protein phosphatase 1, catalytic subunit, alpha isozyme
chr13_+_49280619 3.379 NM_020377
CYSLTR2
cysteinyl leukotriene receptor 2
chr2_-_175547471 3.374 NM_001077269
WIPF1
WAS/WASL interacting protein family, member 1
chr9_-_117150217 3.351 AKNA
AT-hook transcription factor
chr17_-_18950238 3.321 NM_006613
GRAP
GRB2-related adaptor protein
chr7_+_143078399 3.297 ZYX
zyxin
chr4_-_155533800 3.265 FGG
fibrinogen gamma chain
chr16_+_28996369 3.209 NM_001014987
NM_001014988
NM_014387
LAT


linker for activation of T cells


chr11_-_64510339 3.204 RASGRP2
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr10_-_12238053 3.169 NM_014142
NUDT5
nudix (nucleoside diphosphate linked moiety X)-type motif 5
chr11_-_67169252 3.162 PPP1CA
protein phosphatase 1, catalytic subunit, alpha isozyme
chr1_+_203734283 3.138 NM_001136190
NM_017773
LAX1

lymphocyte transmembrane adaptor 1

chr11_+_128563955 3.105 FLI1
Friend leukemia virus integration 1
chrX_+_48542193 3.087 WAS
Wiskott-Aldrich syndrome (eczema-thrombocytopenia)
chr5_-_171615095 3.086 STK10
serine/threonine kinase 10
chr21_+_43823970 3.066 NM_001001895
NM_001243467
NM_018961
UBASH3A


ubiquitin associated and SH3 domain containing A


chr3_+_30648372 3.053 TGFBR2
transforming growth factor, beta receptor II (70/80kDa)
chr16_+_57702156 3.044 NM_170776
GPR97
G protein-coupled receptor 97
chr20_-_33734894 3.035 EDEM2
ER degradation enhancer, mannosidase alpha-like 2
chr16_+_28996146 3.013 NM_001014989
LAT
linker for activation of T cells
chr5_-_180237114 3.010 NM_001114617
MGAT1
mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
chr11_+_128563973 2.994 FLI1
Friend leukemia virus integration 1
chr3_-_46249787 2.976 NM_001295
CCR1
chemokine (C-C motif) receptor 1
chr3_+_111260925 2.970 NM_005816
NM_198196
CD96

CD96 molecule

chr3_-_121379757 2.965 NM_005335
HCLS1
hematopoietic cell-specific Lyn substrate 1
chr7_+_143078457 2.940 ZYX
zyxin
chr3_-_121379701 2.937 HCLS1
hematopoietic cell-specific Lyn substrate 1
chr12_+_9142136 2.901 NM_005810
KLRG1
killer cell lectin-like receptor subfamily G, member 1
chr11_+_128563993 2.877 FLI1
Friend leukemia virus integration 1
chr12_-_123187842 2.859 NM_177551
HCAR2
hydroxycarboxylic acid receptor 2
chr11_-_67169340 2.831 NM_001008709
NM_002708
NM_206873
PPP1CA


protein phosphatase 1, catalytic subunit, alpha isozyme


chr11_+_128563772 2.810 NM_001167681
NM_002017
FLI1

Friend leukemia virus integration 1

chr8_-_99057594 2.807 RPL30
ribosomal protein L30
chr14_-_25078818 2.801 NM_033423
GZMH
granzyme H (cathepsin G-like 2, protein h-CCPX)
chr10_-_12237840 2.792 NUDT5
nudix (nucleoside diphosphate linked moiety X)-type motif 5
chr12_-_123201319 2.783 NM_006018
HCAR3
hydroxycarboxylic acid receptor 3
chr17_-_3867585 2.765 NM_005173
NM_174953
NM_174954
NM_174955
NM_174956
NM_174957
NM_174958
ATP2A3






ATPase, Ca++ transporting, ubiquitous






chr17_+_76126835 2.749 NM_152468
TMC8
transmembrane channel-like 8
chr2_-_136873740 2.747 NM_001008540
CXCR4
chemokine (C-X-C motif) receptor 4
chr16_+_29674282 2.718 NM_001030288
SPN
sialophorin
chr7_+_143078447 2.716 ZYX
zyxin
chr11_+_1874199 2.703 NM_002339
LSP1
lymphocyte-specific protein 1
chr10_+_1102741 2.700 NM_014023
WDR37
WD repeat domain 37
chr7_+_143078444 2.694 ZYX
zyxin
chr19_-_38916801 2.693 NM_001146202
NM_001146203
NM_001146204
NM_001146205
NM_001146206
NM_001146207
NM_170604
RASGRP4






RAS guanyl releasing protein 4






chr11_+_128564130 2.687 FLI1
Friend leukemia virus integration 1
chr9_+_214860 2.674 NM_203447
DOCK8
dedicator of cytokinesis 8
chr2_-_161349874 2.669 RBMS1
RNA binding motif, single stranded interacting protein 1
chr7_+_143078358 2.661 NM_001010972
NM_003461
ZYX

zyxin

chr19_-_6670078 2.659 TNFSF14
tumor necrosis factor (ligand) superfamily, member 14
chr17_-_56409868 2.633


chr1_-_111746917 2.633 DENND2D
DENN/MADD domain containing 2D
chr1_-_161039703 2.629 ARHGAP30
Rho GTPase activating protein 30
chr3_-_32544319 2.629 CMTM6
CKLF-like MARVEL transmembrane domain containing 6
chr19_+_14492209 2.599 CD97
CD97 molecule
chrX_+_48542159 2.596 NM_000377
WAS
Wiskott-Aldrich syndrome (eczema-thrombocytopenia)
chrX_+_119738542 2.593 NM_001137554
MCTS1
malignant T cell amplified sequence 1
chr5_+_35856990 2.592 NM_002185
IL7R
interleukin 7 receptor
chr19_-_14887623 2.591 EMR2
egf-like module containing, mucin-like, hormone receptor-like 2
chr14_+_61788398 2.573 NM_006255
PRKCH
protein kinase C, eta
chr17_-_78388812 2.559 LOC100294362
uncharacterized LOC100294362
chr7_+_143078608 2.549 ZYX
zyxin
chr7_+_106505739 2.518 PIK3CG
phosphoinositide-3-kinase, catalytic, gamma polypeptide
chr3_-_112693711 2.516 NM_138806
NM_138939
NM_138940
NM_170780
CD200R1



CD200 receptor 1



chr17_-_42466840 2.514 NM_000419
ITGA2B
integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
chr4_-_155533757 2.511 FGG
fibrinogen gamma chain
chr1_-_161039745 2.499 NM_001025598
NM_181720
ARHGAP30

Rho GTPase activating protein 30

chr1_-_111217275 2.486 KCNA3
potassium voltage-gated channel, shaker-related subfamily, member 3
chr11_-_417324 2.483 NM_001135053
NM_021805
SIGIRR

single immunoglobulin and toll-interleukin 1 receptor (TIR) domain

chr13_-_46756291 2.478 LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr22_-_50968475 2.473 NM_001113755
NM_001953
TYMP

thymidine phosphorylase

chr10_-_98480174 2.459 NM_152309
PIK3AP1
phosphoinositide-3-kinase adaptor protein 1
chr19_+_55417507 2.444 NM_001145457
NM_001145458
NM_001242356
NM_001242357
NM_004829
NCR1




natural cytotoxicity triggering receptor 1




chr3_+_108541544 2.431 NM_016388
TRAT1
T cell receptor associated transmembrane adaptor 1
chr19_+_41082729 2.427 NM_138392
SHKBP1
SH3KBP1 binding protein 1
chr14_-_24036939 2.421 AP1G2
adaptor-related protein complex 1, gamma 2 subunit
chr3_+_114012832 2.411 NM_173799
TIGIT
T cell immunoreceptor with Ig and ITIM domains
chr22_+_17565899 2.401 IL17RA
interleukin 17 receptor A
chr22_+_47158517 2.341 NM_014346
TBC1D22A
TBC1 domain family, member 22A
chr19_-_47217576 2.325 NM_001079882
PRKD2
protein kinase D2
chr11_-_72433379 2.325 NM_001135190
NM_015242
ARAP1

ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1

chr6_-_2842069 2.324 NM_030666
SERPINB1
serpin peptidase inhibitor, clade B (ovalbumin), member 1
chr12_-_10151689 2.315 NM_001099431
NM_016509
CLEC1B

C-type lectin domain family 1, member B

chr14_+_24912177 2.307


chr1_-_92949500 2.292 GFI1
growth factor independent 1 transcription repressor
chr15_-_90347173 2.274 ANPEP
alanyl (membrane) aminopeptidase
chr1_-_31230673 2.262 NM_006762
LAPTM5
lysosomal protein transmembrane 5
chr19_-_17958814 2.258 NM_000215
JAK3
Janus kinase 3
chr9_-_134151905 2.256 NM_033387
FAM78A
family with sequence similarity 78, member A
chr16_-_67193804 2.253 NM_003789
TRADD
TNFRSF1A-associated via death domain
chr13_-_46756326 2.252 NM_002298
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr16_-_67193762 2.252 TRADD
TNFRSF1A-associated via death domain
chr16_+_29674568 2.250 NM_003123
SPN
sialophorin
chr13_-_46756295 2.248 LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr10_-_43904598 2.219 NM_004966
NM_001098204
HNRNPF

heterogeneous nuclear ribonucleoprotein F

chr19_+_41082980 2.218 SHKBP1
SH3KBP1 binding protein 1
chr1_-_20834516 2.194 MUL1
mitochondrial E3 ubiquitin protein ligase 1
chr19_-_8567473 2.185 NM_032152
PRAM1
PML-RARA regulated adaptor molecule 1
chr5_-_140012730 2.171 CD14
CD14 molecule
chr19_+_41082792 2.170 SHKBP1
SH3KBP1 binding protein 1
chr20_+_35201948 2.170 NM_021809
TGIF2
TGFB-induced factor homeobox 2
chr16_+_29674564 2.164 SPN
sialophorin
chr7_+_106505696 2.147 PIK3CG
phosphoinositide-3-kinase, catalytic, gamma polypeptide
chr9_-_35103144 2.134 NM_013442
STOML2
stomatin (EPB72)-like 2
chr19_+_56165415 2.123 NM_001012478
NM_007279
U2AF2

U2 small nuclear RNA auxiliary factor 2

chr1_+_206730893 2.116 RASSF5
Ras association (RalGDS/AF-6) domain family member 5
chr8_-_99057751 2.115 RPL30
ribosomal protein L30
chr5_-_101631965 2.115 NM_180991
SLCO4C1
solute carrier organic anion transporter family, member 4C1
chr17_+_19030781 2.111 NM_001129778
GRAPL
GRB2-related adaptor protein-like
chr1_-_183559669 2.108 NM_000433
NM_001190789
NM_001190794
NCF2


neutrophil cytosolic factor 2


chr1_-_31230594 2.107 LAPTM5
lysosomal protein transmembrane 5
chr11_-_414975 2.105 NM_001135054
SIGIRR
single immunoglobulin and toll-interleukin 1 receptor (TIR) domain
chr13_-_74707913 2.099 NM_007249
KLF12
Kruppel-like factor 12
chr1_+_206730497 2.093 RASSF5
Ras association (RalGDS/AF-6) domain family member 5
chr12_+_89744714 2.085 LOC100131490
uncharacterized LOC100131490
chr6_-_36515245 2.081 NM_007271
STK38
serine/threonine kinase 38
chr10_-_43904306 2.077 NM_001098205
HNRNPF
heterogeneous nuclear ribonucleoprotein F
chr6_-_2842112 2.072 SERPINB1
serpin peptidase inhibitor, clade B (ovalbumin), member 1
chr5_-_140998567 2.070 NM_001079812
NM_005219
DIAPH1

diaphanous homolog 1 (Drosophila)

chr19_-_17958773 2.058 JAK3
Janus kinase 3
chr19_+_14491920 2.055 NM_001025160
NM_001784
NM_078481
CD97


CD97 molecule


chr9_+_214867 2.052 DOCK8
dedicator of cytokinesis 8
chr17_-_4851797 2.039 NM_005022
PFN1
profilin 1
chr10_+_49892860 2.036 WDFY4
WDFY family member 4
chr2_+_103035148 2.026 NM_003853
IL18RAP
interleukin 18 receptor accessory protein
chr15_-_40599872 2.026 PLCB2
phospholipase C, beta 2
chr1_+_206730591 2.017 RASSF5
Ras association (RalGDS/AF-6) domain family member 5
chr5_-_171615199 2.006 STK10
serine/threonine kinase 10
chr5_-_171615239 1.998 STK10
serine/threonine kinase 10
chr19_+_42387307 1.997 ARHGEF1
Rho guanine nucleotide exchange factor (GEF) 1
chr10_+_114206708 1.995 NM_145206
VTI1A
vesicle transport through interaction with t-SNAREs homolog 1A (yeast)
chr7_-_143105897 1.995 NM_005232
EPHA1
EPH receptor A1
chr11_-_61129462 1.994 NM_001161454
NM_153611
CYBASC3

cytochrome b, ascorbate dependent 3

chr8_-_99057766 1.992 NM_000989
RPL30
ribosomal protein L30
chr6_-_153304093 1.989 NM_012177
FBXO5
F-box protein 5
chr5_-_180236816 1.988 NM_001114618
MGAT1
mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
chr5_-_140998563 1.966 DIAPH1
diaphanous homolog 1 (Drosophila)
chr12_-_57871631 1.952 NM_001080156
ARHGAP9
Rho GTPase activating protein 9
chr1_-_202129705 1.948 PTPN7
protein tyrosine phosphatase, non-receptor type 7
chr14_+_75988838 1.946 BATF
basic leucine zipper transcription factor, ATF-like
chr7_-_3083346 1.939 NM_032415
CARD11
caspase recruitment domain family, member 11
chr3_-_50649080 1.939 CISH
cytokine inducible SH2-containing protein
chr7_+_44084306 1.936 DBNL
drebrin-like
chr12_-_57873628 1.935 NM_032496
ARHGAP9
Rho GTPase activating protein 9
chr10_+_8097350 1.934 GATA3
GATA binding protein 3
chr19_+_55897302 1.931 RPL28
ribosomal protein L28
chr17_-_80408609 1.929 C17orf62
chromosome 17 open reading frame 62
chr1_+_155178489 1.913 NM_002455
NM_198883
MTX1

metaxin 1

chr20_+_49126920 1.909 PTPN1
protein tyrosine phosphatase, non-receptor type 1
chr5_-_39219578 1.902 NM_001465
NM_199335
FYB

FYN binding protein

chr16_+_77225369 1.901 MON1B
MON1 homolog B (yeast)
chr12_-_54653369 1.897 NM_001127321
CBX5
chromobox homolog 5
chr20_-_34542205 1.896 SCAND1
SCAN domain containing 1

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
3.25 5.51e-21 GO:0002376 immune system process
4.19 5.07e-14 GO:0001775 cell activation
3.47 1.06e-12 GO:0002682 regulation of immune system process
3.33 1.81e-12 GO:0006955 immune response
6.23 4.34e-12 GO:0046649 lymphocyte activation
5.53 5.19e-12 GO:0045321 leukocyte activation
3.86 3.95e-10 GO:0050776 regulation of immune response
1.79 1.13e-09 GO:0007165 signal transduction
7.32 1.21e-09 GO:0042110 T cell activation
2.15 1.97e-09 GO:0048583 regulation of response to stimulus
1.25 1.88e-08 GO:0009987 cellular process
7.69 2.21e-08 GO:0050851 antigen receptor-mediated signaling pathway
3.61 2.45e-08 GO:0002684 positive regulation of immune system process
1.62 8.80e-08 GO:0051716 cellular response to stimulus
7.08 9.40e-08 GO:0002429 immune response-activating cell surface receptor signaling pathway
6.81 1.84e-07 GO:0002768 immune response-regulating cell surface receptor signaling pathway
5.27 2.99e-07 GO:0050863 regulation of T cell activation
7.95 6.82e-07 GO:0050852 T cell receptor signaling pathway
4.61 7.43e-07 GO:0051249 regulation of lymphocyte activation
4.36 1.06e-06 GO:0002694 regulation of leukocyte activation
1.62 1.44e-06 GO:0023052 signaling
4.19 2.39e-06 GO:0050865 regulation of cell activation
6.69 2.59e-06 GO:0030098 lymphocyte differentiation
1.42 4.30e-06 GO:0050896 response to stimulus
1.36 5.25e-06 GO:0050789 regulation of biological process
8.33 5.37e-06 GO:0030217 T cell differentiation
4.85 8.70e-06 GO:0051251 positive regulation of lymphocyte activation
5.34 1.08e-05 GO:0050870 positive regulation of T cell activation
4.65 1.80e-05 GO:0002757 immune response-activating signal transduction
5.45 2.06e-05 GO:0002521 leukocyte differentiation
4.54 2.67e-05 GO:0002764 immune response-regulating signaling pathway
4.52 2.94e-05 GO:0002696 positive regulation of leukocyte activation
1.35 3.00e-05 GO:0050794 regulation of cellular process
3.67 3.66e-05 GO:0050778 positive regulation of immune response
4.44 3.93e-05 GO:0050867 positive regulation of cell activation
1.89 4.66e-05 GO:0007166 cell surface receptor linked signaling pathway
2.35 5.81e-05 GO:0009611 response to wounding
3.85 1.06e-04 GO:0030097 hemopoiesis
1.30 1.26e-04 GO:0065007 biological regulation
3.92 1.57e-04 GO:0002253 activation of immune response
3.60 1.87e-04 GO:0048534 hemopoietic or lymphoid organ development
2.82 2.30e-04 GO:0007599 hemostasis
2.35 3.09e-04 GO:0048584 positive regulation of response to stimulus
2.75 6.25e-04 GO:0007596 blood coagulation
2.75 6.25e-04 GO:0050817 coagulation
3.34 7.24e-04 GO:0002520 immune system development
2.53 1.17e-03 GO:0042060 wound healing
4.33 1.38e-03 GO:0002697 regulation of immune effector process
1.61 1.44e-03 GO:0048518 positive regulation of biological process
1.65 1.66e-03 GO:0006950 response to stress
2.47 4.15e-03 GO:0050878 regulation of body fluid levels
7.30 4.51e-03 GO:0042102 positive regulation of T cell proliferation
1.85 5.29e-03 GO:0009966 regulation of signal transduction
2.15 7.01e-03 GO:0006952 defense response
3.24 1.08e-02 GO:0030036 actin cytoskeleton organization
5.76 1.19e-02 GO:0042129 regulation of T cell proliferation
5.52 1.76e-02 GO:0042113 B cell activation
22.71 1.84e-02 GO:0010819 regulation of T cell chemotaxis
22.71 1.84e-02 GO:0010820 positive regulation of T cell chemotaxis
22.71 1.84e-02 GO:2000401 regulation of lymphocyte migration
22.71 1.84e-02 GO:2000403 positive regulation of lymphocyte migration
22.71 1.84e-02 GO:2000404 regulation of T cell migration
22.71 1.84e-02 GO:2000406 positive regulation of T cell migration
5.45 2.00e-02 GO:0050671 positive regulation of lymphocyte proliferation
5.37 2.26e-02 GO:0032946 positive regulation of mononuclear cell proliferation
5.30 2.54e-02 GO:0070665 positive regulation of leukocyte proliferation
1.80 2.63e-02 GO:0035556 intracellular signal transduction
3.76 3.30e-02 GO:0050900 leukocyte migration
5.77 3.33e-02 GO:0002831 regulation of response to biotic stimulus
2.95 4.07e-02 GO:0001817 regulation of cytokine production

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
23.18 1.02e-06 GO:0042101 T cell receptor complex
1.10 4.79e-05 GO:0044464 cell part
1.10 4.88e-05 GO:0005623 cell
1.26 1.87e-04 GO:0005737 cytoplasm
1.65 1.07e-03 GO:0005829 cytosol
4.15 1.74e-03 GO:0043235 receptor complex
3.76 5.45e-03 GO:0045121 membrane raft
3.75 1.11e-02 GO:0009897 external side of plasma membrane
2.64 2.97e-02 GO:0015629 actin cytoskeleton

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
1.31 6.26e-05 GO:0005515 protein binding
2.69 3.37e-04 GO:0030695 GTPase regulator activity
2.62 5.83e-04 GO:0060589 nucleoside-triphosphatase regulator activity
4.79 1.04e-03 GO:0019955 cytokine binding
12.55 1.60e-03 GO:0005164 tumor necrosis factor receptor binding
2.01 2.45e-03 GO:0030234 enzyme regulator activity
4.34 6.80e-03 GO:0017124 SH3 domain binding
2.87 2.07e-02 GO:0005096 GTPase activator activity
7.69 3.37e-02 GO:0032813 tumor necrosis factor receptor superfamily binding
9.94 3.54e-02 GO:0001637 G-protein chemoattractant receptor activity
9.94 3.54e-02 GO:0004950 chemokine receptor activity