Motif ID: EP300.p2

Z-value: 1.444


Transcription factors associated with EP300.p2:

Gene SymbolEntrez IDGene Name
EP300 2033 E1A binding protein p300

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
EP300hg19_v1_chr22_+_41488607_41488645-0.327.1e-02Click!


Activity profile for motif EP300.p2.

activity profile for motif EP300.p2


Sorted Z-values histogram for motif EP300.p2

Sorted Z-values for motif EP300.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of EP300.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_-_95007139 7.909 NM_001178096
NM_001993
 F3

coagulation factor III (thromboplastin, tissue factor)

chr1_+_153651050 3.883 NM_000906
 NPR1
natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A)
chr13_+_37248048 2.739 NM_203451
 SERTM1
serine-rich and transmembrane domain containing 1
chr19_-_46916825 2.564 NM_032040
 CCDC8
coiled-coil domain containing 8
chr4_-_121993568 2.558 NM_024574
 NDNF
neuron-derived neurotrophic factor
chr1_+_157963310 2.529 KIRREL
kin of IRRE like (Drosophila)
chr16_+_66400524 2.526 NM_001795
 CDH5
cadherin 5, type 2 (vascular endothelium)
chr8_+_106331146 2.524 NM_012082
 ZFPM2
zinc finger protein, multitype 2
chr12_-_48152180 2.498 NM_001098532
NM_006105
 RAPGEF3

Rap guanine nucleotide exchange factor (GEF) 3

chr2_+_217498082 2.497 NM_000597
 IGFBP2
insulin-like growth factor binding protein 2, 36kDa
chr11_-_63258410 2.465 NM_001146728
NM_001146729
NM_054108
 HRASLS5


HRAS-like suppressor family, member 5


chr11_-_2160199 2.454 NM_000612
 IGF2
insulin-like growth factor 2 (somatomedin A)
chr17_+_72427535 2.402 NM_022036
 GPRC5C
G protein-coupled receptor, family C, group 5, member C
chr15_-_23932410 2.396 NM_002487
 NDN
necdin homolog (mouse)
chr15_+_71184781 2.338 NM_001199017
NM_017691
NM_001199018
 LRRC49


leucine rich repeat containing 49


chr1_+_57110745 2.319 NM_006252
 PRKAA2
protein kinase, AMP-activated, alpha 2 catalytic subunit
chr2_-_110371669 2.293 NM_144710
NM_178584
 SEPT10

septin 10

chr1_-_156647088 2.292 NM_006617
 NES
nestin
chr15_-_23932364 2.254


chr13_-_40177355 2.250 NM_005780
 LHFP
lipoma HMGIC fusion partner

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 21 entries
Enrichment   P-value GO Accession GO Term
6.47 2.82e-02 GO:0060537 muscle tissue development
4.84 6.34e-03 GO:0061061 muscle structure development
4.30 4.26e-03 GO:0043009 chordate embryonic development
4.25 4.87e-03 GO:0009792 embryo development ending in birth or egg hatching
3.32 4.14e-02 GO:0008284 positive regulation of cell proliferation
2.90 2.21e-03 GO:0042127 regulation of cell proliferation
2.90 2.58e-02 GO:0007155 cell adhesion
2.90 2.58e-02 GO:0022610 biological adhesion
2.66 1.01e-04 GO:0009653 anatomical structure morphogenesis
2.17 1.93e-03 GO:0048869 cellular developmental process
2.10 8.14e-06 GO:0048856 anatomical structure development
2.09 8.20e-05 GO:0048731 system development
2.06 1.68e-02 GO:0030154 cell differentiation
1.99 2.98e-05 GO:0007275 multicellular organismal development
1.97 8.71e-06 GO:0032502 developmental process
1.87 2.24e-04 GO:0023052 signaling
1.75 1.81e-02 GO:0007165 signal transduction
1.66 4.33e-04 GO:0032501 multicellular organismal process
1.44 1.34e-02 GO:0050794 regulation of cellular process
1.41 2.30e-02 GO:0050789 regulation of biological process

Gene overrepresentation in compartment category:

Showing 1 to 8 of 8 entries
Enrichment   P-value GO Accession GO Term
6.21 7.46e-04 GO:0016324 apical plasma membrane
4.95 5.42e-03 GO:0045177 apical part of cell
3.76 6.75e-03 GO:0031012 extracellular matrix
2.38 2.11e-02 GO:0044421 extracellular region part
1.92 1.66e-02 GO:0005576 extracellular region
1.90 1.26e-02 GO:0044459 plasma membrane part
1.58 1.27e-02 GO:0071944 cell periphery
1.58 1.64e-02 GO:0005886 plasma membrane

Gene overrepresentation in function category:

Showing 1 to 6 of 6 entries
Enrichment   P-value GO Accession GO Term
104.25 1.58e-02 GO:0005019 platelet-derived growth factor beta-receptor activity
69.50 4.70e-02 GO:0004992 platelet activating factor receptor activity
69.50 4.70e-02 GO:0005017 platelet-derived growth factor receptor activity
69.50 4.70e-02 GO:0016941 natriuretic peptide receptor activity
9.93 5.30e-03 GO:0004714 transmembrane receptor protein tyrosine kinase activity
7.73 2.20e-02 GO:0019199 transmembrane receptor protein kinase activity