Motif ID: ESR1.p2

Z-value: 1.337


Transcription factors associated with ESR1.p2:

Gene SymbolEntrez IDGene Name
ESR1 2099 estrogen receptor 1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
ESR1hg19_v1_chr6_+_152128685_1521290470.106.0e-01Click!


Activity profile for motif ESR1.p2.

activity profile for motif ESR1.p2


Sorted Z-values histogram for motif ESR1.p2

Sorted Z-values for motif ESR1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ESR1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr5_+_150400132 2.207 GPX3
glutathione peroxidase 3 (plasma)
chr22_-_43116796 2.074 NM_017436
 A4GALT
alpha 1,4-galactosyltransferase
chr3_-_81810802 1.924 GBE1
glucan (1,4-alpha-), branching enzyme 1
chr13_+_110959592 1.899 NM_001846
 COL4A2
collagen, type IV, alpha 2
chr3_-_81810816 1.847 GBE1
glucan (1,4-alpha-), branching enzyme 1
chr22_-_43117270 1.842 A4GALT
alpha 1,4-galactosyltransferase
chr3_-_133748727 1.836 SLCO2A1
solute carrier organic anion transporter family, member 2A1
chr13_-_110959441 1.828 NM_001845
 COL4A1
collagen, type IV, alpha 1
chr2_+_36582812 1.826 CRIM1
cysteine rich transmembrane BMP regulator 1 (chordin-like)
chr3_-_133748828 1.805 NM_005630
 SLCO2A1
solute carrier organic anion transporter family, member 2A1
chr3_+_154797435 1.788 NM_000902
 MME
membrane metallo-endopeptidase
chr3_-_81810796 1.757 GBE1
glucan (1,4-alpha-), branching enzyme 1
chr3_-_81810618 1.672 GBE1
glucan (1,4-alpha-), branching enzyme 1
chr5_+_150399980 1.647 NM_002084
 GPX3
glutathione peroxidase 3 (plasma)
chr19_+_15218141 1.616 NM_033025
 SYDE1
synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
chr20_+_55204307 1.609 NM_003222
 TFAP2C
transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
chr6_+_148663728 1.540 NM_015278
 SASH1
SAM and SH3 domain containing 1
chr6_+_148663953 1.528 SASH1
SAM and SH3 domain containing 1
chr14_-_106714594 1.480


chr16_-_75285383 1.477 NM_001170717
NM_014567
 BCAR1

breast cancer anti-estrogen resistance 1


Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 5 of 5 entries
Enrichment   P-value GO Accession GO Term
318.64 3.70e-03 GO:0019063 virion penetration into host cell
318.64 3.70e-03 GO:0019064 viral envelope fusion with host membrane
12.56 1.76e-02 GO:0034329 cell junction assembly
11.32 2.90e-02 GO:0034330 cell junction organization
7.70 4.55e-02 GO:0001568 blood vessel development

Gene overrepresentation in compartment category:

Showing 1 to 2 of 2 entries
Enrichment   P-value GO Accession GO Term
106.23 1.09e-02 GO:0005587 collagen type IV
91.05 1.53e-02 GO:0030935 sheet-forming collagen

Gene overrepresentation in function category:

Showing 1 to 1 of 1 entries
Enrichment   P-value GO Accession GO Term
1.65 8.06e-03 GO:0005515 protein binding