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• Mean activities

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• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)
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Motif ID: ETS1,2.p2

Z-value: 3.676

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr9_-_137809710	16.247	NM_002003	FCN1	ficolin (collagen/fibrinogen domain containing) 1
chr16_+_29674282	12.485	NM_001030288	SPN	sialophorin
chr3_-_183273407	11.539	NM_130446	KLHL6	kelch-like 6 (Drosophila)
chrX_+_65235279	11.395
chr10_-_72362513	10.625	NM_001083116 NM_005041	PRF1	perforin 1 (pore forming protein)
chr16_-_29757264	10.522	NM_175900	C16orf54	chromosome 16 open reading frame 54
chr13_-_46756295	10.134		LCP1	lymphocyte cytosolic protein 1 (L-plastin)
chr19_+_49838734	9.990		CD37	CD37 molecule
chr10_+_81370694	9.702	NM_001093770 NM_001164644 NM_001164645 NM_001164646 NM_001164647 NM_005411	SFTPA1	surfactant protein A1
chr19_+_49838700	9.515		CD37	CD37 molecule
chr10_-_72362441	9.425		PRF1	perforin 1 (pore forming protein)
chr7_-_3083346	9.273	NM_032415	CARD11	caspase recruitment domain family, member 11
chr9_+_137772653	9.227	NM_004108 NM_015837	FCN2	ficolin (collagen/fibrinogen domain containing lectin) 2 (hucolin)
chr14_-_94856926	8.885	NM_001002235 NM_001002236 NM_001127700 NM_001127701 NM_001127702 NM_001127703 NM_001127704 NM_001127705 NM_001127706 NM_001127707	SERPINA1	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chr6_+_31553955	8.836	NM_205838 NM_205839	LST1	leukocyte specific transcript 1
chr3_+_32993065	8.714	NM_005508	CCR4	chemokine (C-C motif) receptor 4
chr16_+_29674568	8.652	NM_003123	SPN	sialophorin
chr19_+_49838673	8.540	NM_001040031 NM_001774	CD37	CD37 molecule
chr10_+_49893514	8.359	NM_020945	WDFY4	WDFY family member 4
chr16_+_30483959	8.296	NM_001114380 NM_002209	ITGAL	integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
chr7_+_50348255	8.293		IKZF1	IKAROS family zinc finger 1 (Ikaros)
chr7_-_45018650	7.845		MYO1G	myosin IG
chr13_-_46756326	7.731	NM_002298	LCP1	lymphocyte cytosolic protein 1 (L-plastin)
chr19_+_49838646	7.651		CD37	CD37 molecule
chr7_-_45018677	7.626	NM_033054	MYO1G	myosin IG
chr16_+_30484049	7.583		ITGAL	integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
chr1_-_161601752	7.557	NM_000570	FCGR3B	Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
chr16_+_29674564	7.520		SPN	sialophorin
chr16_+_30194925	7.409		CORO1A	coronin, actin binding protein, 1A
chr21_-_46340874	7.333	NM_000211	ITGB2	integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr21_-_46340821	7.285		ITGB2	integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr11_+_67171400	7.257	NM_198517	TBC1D10C	TBC1 domain family, member 10C
chr21_-_15918635	7.171	NM_022136	SAMSN1	SAM domain, SH3 domain and nuclear localization signals 1
chr1_+_111415721	7.170	NM_000560	CD53	CD53 molecule
chr14_-_106586333	7.026		IGHV4-31	immunoglobulin heavy variable 4-31
chr1_-_31230594	6.980		LAPTM5	lysosomal protein transmembrane 5
chr19_-_4540035	6.963	NM_052972	LRG1	leucine-rich alpha-2-glycoprotein 1
chr7_-_45018559	6.946		MYO1G	myosin IG
chr1_+_203734283	6.917	NM_001136190 NM_017773	LAX1	lymphocyte transmembrane adaptor 1
chr13_-_46756291	6.908		LCP1	lymphocyte cytosolic protein 1 (L-plastin)
chr19_+_3178735	6.871	NM_003775	S1PR4	sphingosine-1-phosphate receptor 4
chr13_+_31287614	6.732	NM_001204406	ALOX5AP	arachidonate 5-lipoxygenase-activating protein
chr10_+_49892860	6.667		WDFY4	WDFY family member 4
chr1_-_161039413	6.548		ARHGAP30	Rho GTPase activating protein 30
chr1_-_161520412	6.500	NM_001127593 NM_001127595 NM_001127596	FCGR3A	Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
chr22_+_44577215	6.462		PARVG	parvin, gamma
chr1_+_111415791	6.392		CD53	CD53 molecule
chr10_+_26727651	6.376		APBB1IP	amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
chr10_+_26727692	6.309		APBB1IP	amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
chr1_-_157522151	6.184	NM_001195388 NM_031281	FCRL5	Fc receptor-like 5
chr4_+_2813966	6.160		SH3BP2	SH3-domain binding protein 2
chr15_+_81589240	6.134	NM_004513	IL16	interleukin 16
chr21_-_46340776	6.133		ITGB2	integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr8_+_56792392	6.061		LYN	v-yes-1 Yamaguchi sarcoma viral related oncogene homolog
chr15_+_75074417	6.053	NM_001127190 NM_004383	CSK	c-src tyrosine kinase
chr11_+_67171379	5.915		TBC1D10C	TBC1 domain family, member 10C
chr8_+_56792345	5.903	NM_001111097 NM_002350	LYN	v-yes-1 Yamaguchi sarcoma viral related oncogene homolog
chr2_+_113931549	5.847	NM_012455	PSD4	pleckstrin and Sec7 domain containing 4
chr16_-_50715116	5.784		SNX20	sorting nexin 20
chr11_+_60223281	5.759	NM_021950 NM_152866	MS4A1	membrane-spanning 4-domains, subfamily A, member 1
chr12_+_7055753	5.743		PTPN6	protein tyrosine phosphatase, non-receptor type 6
chr1_-_161039649	5.714		ARHGAP30	Rho GTPase activating protein 30
chr1_-_31230673	5.711	NM_006762	LAPTM5	lysosomal protein transmembrane 5
chr19_+_42381189	5.696	NM_001783 NM_021601	CD79A	CD79a molecule, immunoglobulin-associated alpha
chr22_+_44576769	5.695	NM_022141	PARVG	parvin, gamma
chr12_+_7055736	5.606	NM_080548	PTPN6	protein tyrosine phosphatase, non-receptor type 6
chr22_-_37545944	5.592	NM_000878	IL2RB	interleukin 2 receptor, beta
chr22_+_37678565	5.465		CYTH4	cytohesin 4
chr2_+_103035148	5.443	NM_003853	IL18RAP	interleukin 18 receptor accessory protein
chr8_+_56792399	5.405		LYN	v-yes-1 Yamaguchi sarcoma viral related oncogene homolog
chr16_-_30394133	5.388	NM_052838	SEPT1	septin 1
chr14_+_21249209	5.377	NM_005615	RNASE6	ribonuclease, RNase A family, k6
chr10_+_129705359	5.327		PTPRE	protein tyrosine phosphatase, receptor type, E
chr1_-_161039586	5.275		ARHGAP30	Rho GTPase activating protein 30
chr2_+_113931565	5.227		PSD4	pleckstrin and Sec7 domain containing 4
chr6_+_36973409	5.182	NM_173558	FGD2	FYVE, RhoGEF and PH domain containing 2
chr22_+_37257004	5.145	NM_000631 NM_013416	NCF4	neutrophil cytosolic factor 4, 40kDa
chr19_-_8567473	5.066	NM_032152	PRAM1	PML-RARA regulated adaptor molecule 1
chr19_+_42387249	5.060	NM_004706 NM_198977	ARHGEF1	Rho guanine nucleotide exchange factor (GEF) 1
chr5_+_57787260	5.020	NM_152687	GAPT	GRB2-binding adaptor protein, transmembrane
chr20_-_1638359	5.019	NM_001039508 NM_018556 NM_080816	SIRPG	signal-regulatory protein gamma
chr22_-_17680485	5.009	NM_177405	CECR1	cat eye syndrome chromosome region, candidate 1
chr20_-_35274557	5.002	NM_032214 NM_175077	SLA2	Src-like-adaptor 2
chr1_+_6086369	4.995		KCNAB2	potassium voltage-gated channel, shaker-related subfamily, beta member 2
chr14_-_23284617	4.992		SLC7A7	solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr19_-_10450262	4.911	NM_002162	ICAM3	intercellular adhesion molecule 3
chr12_+_69742130	4.905	NM_000239	LYZ	lysozyme
chr1_+_26644458	4.882		CD52	CD52 molecule
chr12_+_69742140	4.809		LYZ	lysozyme
chr9_+_273025	4.791	NM_001190458 NM_001193536	DOCK8	dedicator of cytokinesis 8
chr12_-_9760481	4.788	NM_002258	KLRB1	killer cell lectin-like receptor subfamily B, member 1
chr15_+_81293286	4.777	NM_022566	MESDC1	mesoderm development candidate 1
chr19_+_17634109	4.746	NM_001098524 NM_173544	FAM129C	family with sequence similarity 129, member C
chr15_-_40599872	4.742		PLCB2	phospholipase C, beta 2
chr22_+_44577256	4.721	NM_001137606	PARVG	parvin, gamma
chr1_+_32739711	4.689	NM_001042771	LCK	lymphocyte-specific protein tyrosine kinase
chr4_-_74864296	4.686	NM_002994	CXCL5	chemokine (C-X-C motif) ligand 5
chr22_+_37678519	4.586		CYTH4	cytohesin 4
chr4_-_74853819	4.577	NM_002704	PPBP	pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)
chr22_+_37678423	4.574	NM_013385	CYTH4	cytohesin 4
chr1_-_161519817	4.572	NM_000569 NM_001127592	FCGR3A	Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
chr7_+_150434679	4.568		GIMAP5	GTPase, IMAP family member 5
chr14_-_107048697	4.544		IGHG1	immunoglobulin heavy constant gamma 1 (G1m marker)
chr22_-_18257194	4.535		BID	BH3 interacting domain death agonist
chr15_-_40600118	4.516	NM_004573	PLCB2	phospholipase C, beta 2
chr5_-_180018465	4.466	NM_052863	SCGB3A1	secretoglobin, family 3A, member 1
chr19_+_42387307	4.464		ARHGEF1	Rho guanine nucleotide exchange factor (GEF) 1
chr1_-_183559669	4.422	NM_000433 NM_001190789 NM_001190794	NCF2	neutrophil cytosolic factor 2
chr22_-_37640287	4.356	NM_002872	RAC2	ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr1_-_183559463	4.317		NCF2	neutrophil cytosolic factor 2
chr17_-_7017971	4.309		ASGR2	asialoglycoprotein receptor 2
chr12_+_9142136	4.308	NM_005810	KLRG1	killer cell lectin-like receptor subfamily G, member 1
chr11_-_67771527	4.275	NM_030930	UNC93B1	unc-93 homolog B1 (C. elegans)
chr14_-_106691698	4.267
chr2_+_204801453	4.223	NM_012092	ICOS	inducible T-cell co-stimulator
chrX_+_128913881	4.207	NM_018990	SASH3	SAM and SH3 domain containing 3
chr17_-_38721701	4.200	NM_001838	CCR7	chemokine (C-C motif) receptor 7
chr5_+_35856990	4.195	NM_002185	IL7R	interleukin 7 receptor
chr1_+_32716839	4.184	NM_005356	LCK	lymphocyte-specific protein tyrosine kinase
chr15_-_40600025	4.183		PLCB2	phospholipase C, beta 2
chrX_+_128913897	4.180		SASH3	SAM and SH3 domain containing 3
chr2_+_69001932	4.179	NM_001166276 NM_014882	ARHGAP25	Rho GTPase activating protein 25
chr14_-_106573348	4.159		IGHV4-31 IGHA1 IGHA2 IGHG1 IGHG3 IGHM	immunoglobulin heavy variable 4-31 immunoglobulin heavy constant alpha 1 immunoglobulin heavy constant alpha 2 (A2m marker) immunoglobulin heavy constant gamma 1 (G1m marker) immunoglobulin heavy constant gamma 3 (G3m marker) immunoglobulin heavy constant mu
chr20_+_24929904	4.146		CST7	cystatin F (leukocystatin)
chr2_+_85804613	4.145	NM_003761	VAMP8	vesicle-associated membrane protein 8 (endobrevin)
chr1_+_153330329	4.128	NM_002965	S100A9	S100 calcium binding protein A9
chr6_-_133078894	4.028	NM_001242350 NM_004665	VNN2	vanin 2
chr16_+_30484108	4.027
chr22_-_37640187	4.010		RAC2	ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr2_-_219031646	4.009	NM_000634	CXCR1	chemokine (C-X-C motif) receptor 1
chr12_-_10151689	4.002	NM_001099431 NM_016509	CLEC1B	C-type lectin domain family 1, member B
chr20_+_24929862	3.991	NM_003650	CST7	cystatin F (leukocystatin)
chr5_+_118604417	3.990	NM_001077654	TNFAIP8	tumor necrosis factor, alpha-induced protein 8
chr6_-_133084585	3.964	NM_078488	VNN2	vanin 2
chr14_-_24036532	3.944		AP1G2	adaptor-related protein complex 1, gamma 2 subunit
chr19_+_35940616	3.941	NM_005306	FFAR2	free fatty acid receptor 2
chr14_+_105953531	3.935		CRIP1	cysteine-rich protein 1 (intestinal)
chr11_-_67205151	3.927	NM_005608	PTPRCAP	protein tyrosine phosphatase, receptor type, C-associated protein
chr8_-_126963395	3.926		LOC100130231	uncharacterized LOC100130231
chr19_+_55385548	3.915	NM_002000 NM_133269 NM_133271 NM_133272 NM_133273 NM_133274 NM_133277 NM_133278 NM_133279	FCAR	Fc fragment of IgA, receptor for
chr12_+_89744714	3.776		LOC100131490	uncharacterized LOC100131490
chr15_+_75074714	3.770		CSK	c-src tyrosine kinase
chr9_-_114937464	3.763	NM_022486	SUSD1	sushi domain containing 1
chr1_-_162381805	3.756	NM_053282	SH2D1B	SH2 domain containing 1B
chr11_-_118123001	3.739	NM_198275	MPZL3	myelin protein zero-like 3
chr1_+_6086412	3.716		KCNAB2	potassium voltage-gated channel, shaker-related subfamily, beta member 2
chr5_-_138862342	3.715	NM_198282	TMEM173	transmembrane protein 173
chr6_+_31554475	3.711	NM_205837	LST1	leukocyte specific transcript 1
chr1_+_26644380	3.704	NM_001803	CD52	CD52 molecule
chr7_-_5569200	3.696		ACTB	actin, beta
chr4_-_39033981	3.688	NM_024943	TMEM156	transmembrane protein 156
chr4_+_68424444	3.666	NM_012108	STAP1	signal transducing adaptor family member 1
chr2_-_85895863	3.664	NM_000542 NM_198843	SFTPB	surfactant protein B
chr6_+_31554975	3.655	NM_001166538 NM_007161 NM_205840	LST1	leukocyte specific transcript 1
chr17_-_80275370	3.644	NM_006137	CD7	CD7 molecule
chr3_+_38179968	3.607	NM_001172566 NM_001172567 NM_001172568 NM_001172569 NM_002468	MYD88	myeloid differentiation primary response gene (88)
chr19_-_52255099	3.600	NM_001193306 NM_002029	FPR1	formyl peptide receptor 1
chr2_+_85921413	3.595	NM_006433 NM_012483	GNLY	granulysin
chr1_-_27953046	3.588	NM_001042729	FGR	Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog
chr1_-_183560010	3.577	NM_001127651	NCF2	neutrophil cytosolic factor 2
chr12_-_110888098	3.571		ARPC3	actin related protein 2/3 complex, subunit 3, 21kDa
chr22_+_17565844	3.570	NM_014339	IL17RA	interleukin 17 receptor A
chr2_+_68961912	3.569	NM_001007231 NM_001166277	ARHGAP25	Rho GTPase activating protein 25
chr4_-_153601085	3.562	NM_152680	TMEM154	transmembrane protein 154
chr1_-_27952591	3.562	NM_001042747	FGR	Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog
chr5_+_133451297	3.552	NM_001134851 NM_201632 NM_201634 NM_213648	TCF7	transcription factor 7 (T-cell specific, HMG-box)
chr14_-_106829736	3.543		IGHA1 IGHD IGHG3 IGHM SKAP2	immunoglobulin heavy constant alpha 1 immunoglobulin heavy constant delta immunoglobulin heavy constant gamma 3 (G3m marker) immunoglobulin heavy constant mu src kinase associated phosphoprotein 2
chr19_-_41934634	3.506	NM_198540	B3GNT8	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8
chr10_-_98480174	3.501	NM_152309	PIK3AP1	phosphoinositide-3-kinase adaptor protein 1
chr19_+_16435734	3.498		KLF2	Kruppel-like factor 2 (lung)
chr7_-_138794393	3.472	NM_020119 NM_024625	ZC3HAV1	zinc finger CCCH-type, antiviral 1
chr16_-_3306586	3.471	NM_000243 NM_001198536	MEFV	Mediterranean fever
chrY_+_2709630	3.469		RPS4Y1	ribosomal protein S4, Y-linked 1
chr19_+_17862285	3.460	NM_001161359 NM_015122	FCHO1	FCH domain only 1
chr22_-_42322778	3.441	NM_052945	TNFRSF13C	tumor necrosis factor receptor superfamily, member 13C
chr4_+_2813945	3.418	NM_001145855	SH3BP2	SH3-domain binding protein 2
chr12_-_110888106	3.404		ARPC3	actin related protein 2/3 complex, subunit 3, 21kDa
chr3_+_186714335	3.398
chr6_-_32784727	3.392	NM_002120	HLA-DOB	major histocompatibility complex, class II, DO beta
chr19_+_36393381	3.388	NM_001007469 NM_014266	HCST	hematopoietic cell signal transducer
chr17_-_72527592	3.378	NM_174892	CD300LB	CD300 molecule-like family member b
chr22_-_18257221	3.356		BID	BH3 interacting domain death agonist
chr16_+_28996369	3.344	NM_001014987 NM_001014988 NM_014387	LAT	linker for activation of T cells
chr19_+_55128601	3.332	NM_006669	LILRB1	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1
chr22_+_37309618	3.332	NM_000395	CSF2RB	colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
chr14_+_52327363	3.323		GNG2	guanine nucleotide binding protein (G protein), gamma 2
chr10_+_26727282	3.321		APBB1IP	amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
chr19_+_7733971	3.310	NM_001193374 NM_020415	RETN	resistin
chr7_+_150434435	3.286	NM_018384	GIMAP5	GTPase, IMAP family member 5
chr2_+_143886898	3.273	NM_018460	ARHGAP15	Rho GTPase activating protein 15
chrX_-_47489703	3.272	NM_002621	CFP	complement factor properdin
chr12_-_49318663	3.268	NM_001143781	FKBP11	FK506 binding protein 11, 19 kDa
chr7_+_150148078	3.266		GIMAP8	GTPase, IMAP family member 8
chr5_-_138862224	3.253		TMEM173	transmembrane protein 173
chr1_-_160617042	3.250	NM_003037	SLAMF1	signaling lymphocytic activation molecule family member 1
chr1_-_202129118	3.248	NM_080588	PTPN7	protein tyrosine phosphatase, non-receptor type 7
chr12_+_6898699	3.243		CD4	CD4 molecule
chr12_-_110888152	3.235	NM_005719	ARPC3	actin related protein 2/3 complex, subunit 3, 21kDa
chr16_+_28505920	3.235	NM_018690	APOBR	apolipoprotein B receptor
chr12_+_6898705	3.232		CD4	CD4 molecule

Gene overrepresentation in process category:

Enrichment	P-value	GO Accession	GO Term
4.36	1.38e-56	GO:0002376	immune system process
4.86	5.57e-41	GO:0006955	immune response
4.85	1.66e-37	GO:0002682	regulation of immune system process
5.93	1.42e-35	GO:0050776	regulation of immune response
2.81	1.33e-30	GO:0048583	regulation of response to stimulus
5.46	1.14e-29	GO:0002684	positive regulation of immune system process
3.85	1.82e-26	GO:0006952	defense response
1.69	3.19e-25	GO:0050896	response to stimulus
4.76	6.07e-25	GO:0001775	cell activation
6.53	1.66e-23	GO:0050865	regulation of cell activation
6.65	2.24e-23	GO:0002694	regulation of leukocyte activation
6.05	2.28e-23	GO:0050778	positive regulation of immune response
6.87	1.82e-22	GO:0051249	regulation of lymphocyte activation
2.00	3.62e-21	GO:0007165	signal transduction
7.24	3.84e-20	GO:0002757	immune response-activating signal transduction
7.07	9.71e-20	GO:0002764	immune response-regulating signaling pathway
6.25	4.23e-19	GO:0002253	activation of immune response
3.19	2.49e-18	GO:0009611	response to wounding
1.79	2.74e-17	GO:0051716	cellular response to stimulus
1.84	3.95e-17	GO:0023052	signaling
6.71	9.64e-17	GO:0050863	regulation of T cell activation
8.88	1.01e-16	GO:0002429	immune response-activating cell surface receptor signaling pathway
9.31	1.07e-16	GO:0050851	antigen receptor-mediated signaling pathway
3.23	1.46e-16	GO:0048584	positive regulation of response to stimulus
6.39	1.65e-16	GO:0050867	positive regulation of cell activation
8.54	3.33e-16	GO:0002768	immune response-regulating cell surface receptor signaling pathway
6.60	5.56e-16	GO:0051251	positive regulation of lymphocyte activation
6.33	7.53e-16	GO:0002696	positive regulation of leukocyte activation
2.08	1.77e-15	GO:0006950	response to stress
5.25	2.39e-14	GO:0045321	leukocyte activation
6.93	4.96e-14	GO:0050870	positive regulation of T cell activation
3.65	4.61e-13	GO:0007596	blood coagulation
3.65	4.61e-13	GO:0050817	coagulation
3.63	6.13e-13	GO:0007599	hemostasis
5.52	1.68e-12	GO:0046649	lymphocyte activation
2.14	6.91e-12	GO:0007166	cell surface receptor linked signaling pathway
4.92	8.60e-12	GO:0030168	platelet activation
3.24	4.04e-11	GO:0050878	regulation of body fluid levels
1.85	5.63e-11	GO:0048518	positive regulation of biological process
4.30	1.10e-10	GO:0006954	inflammatory response
3.12	1.80e-10	GO:0042060	wound healing
1.36	7.11e-10	GO:0065007	biological regulation
4.23	8.90e-10	GO:0001817	regulation of cytokine production
1.38	1.35e-09	GO:0050789	regulation of biological process
2.21	2.79e-09	GO:0035556	intracellular signal transduction
2.17	4.26e-09	GO:0009966	regulation of signal transduction
10.55	5.95e-09	GO:0045621	positive regulation of lymphocyte differentiation
9.17	1.31e-08	GO:0006968	cellular defense response
5.26	1.57e-08	GO:0002697	regulation of immune effector process
7.42	3.31e-08	GO:0050852	T cell receptor signaling pathway
6.19	9.09e-08	GO:0050670	regulation of lymphocyte proliferation
8.11	1.02e-07	GO:0045619	regulation of lymphocyte differentiation
1.99	1.09e-07	GO:0023051	regulation of signaling
6.13	1.10e-07	GO:0032944	regulation of mononuclear cell proliferation
16.28	1.36e-07	GO:0050853	B cell receptor signaling pathway
2.96	1.42e-07	GO:0080134	regulation of response to stress
5.95	1.92e-07	GO:0070663	regulation of leukocyte proliferation
10.05	3.32e-07	GO:0045582	positive regulation of T cell differentiation
8.84	4.63e-07	GO:0051250	negative regulation of lymphocyte activation
1.35	5.67e-07	GO:0050794	regulation of cellular process
5.24	7.87e-07	GO:0002521	leukocyte differentiation
7.73	8.52e-07	GO:0050864	regulation of B cell activation
3.25	9.20e-07	GO:0045087	innate immune response
7.48	1.40e-06	GO:0031294	lymphocyte costimulation
7.48	1.40e-06	GO:0031295	T cell costimulation
8.17	1.46e-06	GO:0045580	regulation of T cell differentiation
2.35	1.54e-06	GO:0040011	locomotion
5.00	1.93e-06	GO:0001819	positive regulation of cytokine production
5.86	2.11e-06	GO:0030098	lymphocyte differentiation
9.77	2.43e-06	GO:0046634	regulation of alpha-beta T cell activation
2.30	2.84e-06	GO:0051704	multi-organism process
5.74	3.00e-06	GO:0002683	negative regulation of immune system process
7.73	3.23e-06	GO:0002695	negative regulation of leukocyte activation
6.43	4.26e-06	GO:0042035	regulation of cytokine biosynthetic process
3.29	6.20e-06	GO:0031347	regulation of defense response
5.16	6.99e-06	GO:0042110	T cell activation
2.19	7.32e-06	GO:0009605	response to external stimulus
3.68	9.50e-06	GO:0030097	hemopoiesis
4.58	1.00e-05	GO:0002252	immune effector process
7.10	1.08e-05	GO:0050866	negative regulation of cell activation
2.72	1.22e-05	GO:0006935	chemotaxis
2.72	1.22e-05	GO:0042330	taxis
7.73	1.22e-05	GO:0042108	positive regulation of cytokine biosynthetic process
2.94	1.36e-05	GO:0051707	response to other organism
6.36	1.58e-05	GO:0050671	positive regulation of lymphocyte proliferation
6.27	1.92e-05	GO:0032946	positive regulation of mononuclear cell proliferation
4.39	2.13e-05	GO:0050900	leukocyte migration
6.19	2.33e-05	GO:0070665	positive regulation of leukocyte proliferation
8.95	3.31e-05	GO:0030888	regulation of B cell proliferation
5.87	4.89e-05	GO:0043900	regulation of multi-organism process
1.70	4.92e-05	GO:0065008	regulation of biological quality
1.64	5.87e-05	GO:0048522	positive regulation of cellular process
6.02	1.03e-04	GO:0042113	B cell activation
3.29	1.04e-04	GO:0048534	hemopoietic or lymphoid organ development
2.89	1.41e-04	GO:0051056	regulation of small GTPase mediated signal transduction
10.31	1.67e-04	GO:0046637	regulation of alpha-beta T cell differentiation
1.64	1.99e-04	GO:0042221	response to chemical stimulus
2.55	2.29e-04	GO:0009607	response to biotic stimulus
3.17	3.86e-04	GO:0010740	positive regulation of intracellular protein kinase cascade
3.55	4.74e-04	GO:0043405	regulation of MAP kinase activity
3.05	4.90e-04	GO:0002520	immune system development
6.94	5.80e-04	GO:0042102	positive regulation of T cell proliferation
6.94	5.80e-04	GO:0050688	regulation of defense response to virus
8.98	6.39e-04	GO:0046635	positive regulation of alpha-beta T cell activation
1.79	7.96e-04	GO:0065009	regulation of molecular function
12.74	8.58e-04	GO:0043370	regulation of CD4-positive, alpha-beta T cell differentiation
12.74	8.58e-04	GO:2000514	regulation of CD4-positive, alpha-beta T cell activation
7.55	8.66e-04	GO:0050871	positive regulation of B cell activation
5.99	9.53e-04	GO:0002831	regulation of response to biotic stimulus
2.00	1.04e-03	GO:0042127	regulation of cell proliferation
2.68	1.16e-03	GO:0007264	small GTPase mediated signal transduction
2.68	1.16e-03	GO:0010627	regulation of intracellular protein kinase cascade
5.36	1.23e-03	GO:0002699	positive regulation of immune effector process
12.03	1.37e-03	GO:0002702	positive regulation of production of molecular mediator of immune response
3.11	1.59e-03	GO:0009617	response to bacterium
2.59	1.68e-03	GO:0007243	intracellular protein kinase cascade
2.59	1.68e-03	GO:0023014	signal transduction via phosphorylation event
3.67	1.76e-03	GO:0071902	positive regulation of protein serine/threonine kinase activity
2.74	2.55e-03	GO:0051240	positive regulation of multicellular organismal process
5.03	2.65e-03	GO:0048872	homeostasis of number of cells
2.93	2.80e-03	GO:0071900	regulation of protein serine/threonine kinase activity
2.85	2.88e-03	GO:0045860	positive regulation of protein kinase activity
2.22	2.92e-03	GO:0001932	regulation of protein phosphorylation
19.33	2.93e-03	GO:0002532	production of molecular mediator involved in inflammatory response
4.09	2.99e-03	GO:0045089	positive regulation of innate immune response
2.84	3.07e-03	GO:0034097	response to cytokine stimulus
2.36	3.09e-03	GO:0008284	positive regulation of cell proliferation
5.38	3.16e-03	GO:0042129	regulation of T cell proliferation
3.87	3.17e-03	GO:0043406	positive regulation of MAP kinase activity
2.37	3.92e-03	GO:0009967	positive regulation of signal transduction
2.33	4.34e-03	GO:0010647	positive regulation of cell communication
2.31	5.01e-03	GO:0023056	positive regulation of signaling
2.12	5.12e-03	GO:0019220	regulation of phosphate metabolic process
2.12	5.12e-03	GO:0051174	regulation of phosphorus metabolic process
7.14	5.32e-03	GO:0050868	negative regulation of T cell activation
2.76	5.49e-03	GO:0033674	positive regulation of kinase activity
2.13	5.81e-03	GO:0042325	regulation of phosphorylation
2.01	6.33e-03	GO:0044093	positive regulation of molecular function
9.84	6.53e-03	GO:0046638	positive regulation of alpha-beta T cell differentiation
9.84	6.53e-03	GO:0050848	regulation of calcium-mediated signaling
2.39	6.61e-03	GO:0045859	regulation of protein kinase activity
5.49	6.91e-03	GO:0030217	T cell differentiation
3.48	7.35e-03	GO:0031349	positive regulation of defense response
2.67	9.54e-03	GO:0051347	positive regulation of transferase activity
2.93	1.14e-02	GO:0000165	MAPKKK cascade
4.05	1.48e-02	GO:0000187	activation of MAPK activity
2.29	1.57e-02	GO:0043549	regulation of kinase activity
10.92	1.66e-02	GO:0045058	T cell selection
4.28	1.67e-02	GO:0002218	activation of innate immune response
8.33	2.25e-02	GO:0002718	regulation of cytokine production involved in immune response
6.05	2.26e-02	GO:0002700	regulation of production of molecular mediator of immune response
2.00	2.38e-02	GO:0006468	protein phosphorylation
3.49	2.42e-02	GO:0002237	response to molecule of bacterial origin
20.62	2.51e-02	GO:0045586	regulation of gamma-delta T cell differentiation
20.62	2.51e-02	GO:0045588	positive regulation of gamma-delta T cell differentiation
2.21	3.24e-02	GO:0051338	regulation of transferase activity
1.74	3.24e-02	GO:0050790	regulation of catalytic activity
12.89	3.72e-02	GO:0002825	regulation of T-helper 1 type immune response
12.89	3.72e-02	GO:0043372	positive regulation of CD4-positive, alpha-beta T cell differentiation
12.89	3.72e-02	GO:0045577	regulation of B cell differentiation
12.89	3.72e-02	GO:2000516	positive regulation of CD4-positive, alpha-beta T cell activation
7.73	3.83e-02	GO:0030890	positive regulation of B cell proliferation
2.79	3.96e-02	GO:0030036	actin cytoskeleton organization
2.51	4.15e-02	GO:0045597	positive regulation of cell differentiation
2.27	4.69e-02	GO:0051094	positive regulation of developmental process
4.17	4.73e-02	GO:0002221	pattern recognition receptor signaling pathway

Gene overrepresentation in compartment category:

Enrichment	P-value	GO Accession	GO Term
1.88	4.63e-24	GO:0071944	cell periphery
1.87	2.61e-23	GO:0005886	plasma membrane
1.39	1.41e-12	GO:0016020	membrane
1.93	2.78e-11	GO:0044459	plasma membrane part
5.77	2.60e-10	GO:0043235	receptor complex
1.38	2.10e-08	GO:0044425	membrane part
2.09	1.10e-07	GO:0005887	integral to plasma membrane
2.05	2.61e-07	GO:0031226	intrinsic to plasma membrane
1.41	3.02e-07	GO:0016021	integral to membrane
1.40	3.91e-07	GO:0031224	intrinsic to membrane
4.71	8.37e-07	GO:0009897	external side of plasma membrane
18.04	5.70e-06	GO:0042101	T cell receptor complex
2.80	2.63e-05	GO:0009986	cell surface
6.69	4.47e-03	GO:0032587	ruffle membrane
7.47	6.95e-03	GO:0008305	integrin complex
30.93	7.74e-03	GO:0019814	immunoglobulin complex
30.93	7.74e-03	GO:0019815	B cell receptor complex
11.90	8.34e-03	GO:0001772	immunological synapse
2.94	1.72e-02	GO:0031252	cell leading edge
4.35	4.77e-02	GO:0031256	leading edge membrane

Gene overrepresentation in function category:

Enrichment	P-value	GO Accession	GO Term
2.08	4.75e-14	GO:0004871	signal transducer activity
2.08	4.75e-14	GO:0060089	molecular transducer activity
2.12	1.23e-11	GO:0004872	receptor activity
6.30	1.52e-09	GO:0019955	cytokine binding
10.05	7.54e-08	GO:0003823	antigen binding
4.23	2.01e-07	GO:0005529	sugar binding
7.73	7.34e-07	GO:0004896	cytokine receptor activity
23.20	1.10e-05	GO:0019864	IgG binding
2.88	1.31e-05	GO:0030246	carbohydrate binding
2.58	5.80e-05	GO:0030695	GTPase regulator activity
1.27	8.55e-05	GO:0005515	protein binding
2.51	1.13e-04	GO:0060589	nucleoside-triphosphatase regulator activity
13.53	1.18e-04	GO:0019865	immunoglobulin binding
6.19	1.49e-04	GO:0035591	signaling adaptor activity
1.83	2.60e-04	GO:0004888	transmembrane receptor activity
6.31	1.14e-03	GO:0005070	SH3/SH2 adaptor activity
7.14	1.21e-03	GO:0004715	non-membrane spanning protein tyrosine kinase activity
2.85	1.71e-03	GO:0032403	protein complex binding
2.73	7.91e-03	GO:0005096	GTPase activator activity
2.29	1.73e-02	GO:0008047	enzyme activator activity
1.77	2.20e-02	GO:0030234	enzyme regulator activity
10.31	2.96e-02	GO:0008329	pattern recognition receptor activity
3.38	4.71e-02	GO:0030674	protein binding, bridging