Motif ID: EWSR1-FLI1.p2

Z-value: 1.163


Transcription factors associated with EWSR1-FLI1.p2:

fusion protein between EWSR1 and FLI1 in an oncogenic event

Gene SymbolEntrez IDGene Name
EWSR1 2130 Ewing sarcoma breakpoint region 1
FLI1 2313 Friend leukemia virus integration 1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
FLI1hg19_v1_chr11_+_128563955_1285639680.383.2e-02Click!
EWSR1hg19_v1_chr22_+_29663997_29664098-0.038.6e-01Click!


Activity profile for motif EWSR1-FLI1.p2.

activity profile for motif EWSR1-FLI1.p2


Sorted Z-values histogram for motif EWSR1-FLI1.p2

Sorted Z-values for motif EWSR1-FLI1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of EWSR1-FLI1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chrX_+_1401570 10.511 NM_001161530
NM_172247
 CSF2RA

colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)

chrY_+_1351570 10.161 NM_001161530
NM_172247
 CSF2RA

colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)

chr12_-_117175634 5.434 NM_024738
 C12orf49
chromosome 12 open reading frame 49
chr11_+_73357222 3.879 NM_001130033
NM_021200
 PLEKHB1

pleckstrin homology domain containing, family B (evectins) member 1

chr3_-_42307661 3.765 NM_000729
 CCK
cholecystokinin
chr12_-_117175844 3.441 C12orf49
chromosome 12 open reading frame 49
chrX_-_148586666 2.997 NM_000202
NM_001166550
NM_006123
 IDS


iduronate 2-sulfatase


chr19_-_47551881 2.817 NM_017854
 TMEM160
transmembrane protein 160
chr5_-_142000899 2.764 NM_001144892
 FGF1
fibroblast growth factor 1 (acidic)
chr5_+_175108463 2.714 NM_022304
 HRH2
histamine receptor H2
chr9_+_135854097 2.242 NM_001135031
NM_004188
 GFI1B

growth factor independent 1B transcription repressor

chr8_+_133879202 2.119 NM_003235
 TG
thyroglobulin
chr8_-_110986923 2.059 NM_014379
 KCNV1
potassium channel, subfamily V, member 1
chr1_-_31230594 1.984 LAPTM5
lysosomal protein transmembrane 5
chr1_-_169680677 1.978 NM_000655
 SELL
selectin L
chr1_-_31230673 1.931 NM_006762
 LAPTM5
lysosomal protein transmembrane 5
chr5_-_101631965 1.853 NM_180991
 SLCO4C1
solute carrier organic anion transporter family, member 4C1
chr2_+_37571752 1.831 NM_012413
 QPCT
glutaminyl-peptide cyclotransferase
chr5_+_156887026 1.807 NM_001099287
NM_001172292
 NIPAL4

NIPA-like domain containing 4

chrX_+_585078 1.736 NM_000451
NM_006883
 SHOX

short stature homeobox


Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Nothing significant found in function category.