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• Activity deltas table
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Motif ID: FEV.p2

Z-value: 4.651

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr1_+_198608216	12.503		PTPRC	protein tyrosine phosphatase, receptor type, C
chr10_-_72362513	12.366	NM_001083116 NM_005041	PRF1	perforin 1 (pore forming protein)
chr10_-_72362441	11.538		PRF1	perforin 1 (pore forming protein)
chr1_+_198608244	11.478		PTPRC	protein tyrosine phosphatase, receptor type, C
chr19_-_51875790	10.771	NM_005601	NKG7	natural killer cell group 7 sequence
chr1_-_157789832	10.700	NM_001159397 NM_001159398 NM_052938	FCRL1	Fc receptor-like 1
chr6_-_32160289	10.636		GPSM3	G-protein signaling modulator 3
chr1_+_198608136	10.450	NM_002838 NM_080921 NM_080923	PTPRC	protein tyrosine phosphatase, receptor type, C
chr12_-_57871631	10.109	NM_001080156	ARHGAP9	Rho GTPase activating protein 9
chr8_-_82395401	10.054	NM_001442	FABP4	fatty acid binding protein 4, adipocyte
chr3_-_183273407	10.009	NM_130446	KLHL6	kelch-like 6 (Drosophila)
chr19_-_39826625	9.822		GMFG	glia maturation factor, gamma
chr1_-_157522151	9.534	NM_001195388 NM_031281	FCRL5	Fc receptor-like 5
chr12_-_123201319	9.442	NM_006018	HCAR3	hydroxycarboxylic acid receptor 3
chr4_+_40198526	9.432	NM_004310	RHOH	ras homolog gene family, member H
chr6_-_32160637	9.322		GPSM3	G-protein signaling modulator 3
chr7_+_106505739	9.282		PIK3CG	phosphoinositide-3-kinase, catalytic, gamma polypeptide
chr12_-_123187842	8.597	NM_177551	HCAR2	hydroxycarboxylic acid receptor 2
chr2_+_98330030	8.571	NM_001079	ZAP70	zeta-chain (TCR) associated protein kinase 70kDa
chr12_+_69742130	8.335	NM_000239	LYZ	lysozyme
chr19_-_39826676	8.246	NM_004877	GMFG	glia maturation factor, gamma
chr16_+_29674282	8.189	NM_001030288	SPN	sialophorin
chr11_+_60739114	8.174	NM_006725	CD6	CD6 molecule
chr5_+_57787260	8.140	NM_152687	GAPT	GRB2-binding adaptor protein, transmembrane
chr1_-_167487701	8.097	NM_000734 NM_198053	CD247	CD247 molecule
chr2_+_103035148	8.095	NM_003853	IL18RAP	interleukin 18 receptor accessory protein
chr11_-_118084073	8.041	NM_153206	AMICA1	adhesion molecule, interacts with CXADR antigen 1
chr17_-_34417386	8.000	NM_002983	CCL3	chemokine (C-C motif) ligand 3
chr1_+_161676761	7.995	NM_001184866 NM_001184867 NM_001184870 NM_001184871 NM_001184872 NM_001184873 NM_032738	FCRLA	Fc receptor-like A
chr12_-_57873628	7.932	NM_032496	ARHGAP9	Rho GTPase activating protein 9
chr12_+_69742140	7.868		LYZ	lysozyme
chr1_-_183559669	7.859	NM_000433 NM_001190789 NM_001190794	NCF2	neutrophil cytosolic factor 2
chr16_-_29757264	7.739	NM_175900	C16orf54	chromosome 16 open reading frame 54
chr3_+_32993065	7.658	NM_005508	CCR4	chemokine (C-C motif) receptor 4
chr16_+_30484049	7.658		ITGAL	integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
chr16_+_30483959	7.626	NM_001114380 NM_002209	ITGAL	integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
chr7_+_106505696	7.560		PIK3CG	phosphoinositide-3-kinase, catalytic, gamma polypeptide
chr16_+_29674568	7.556	NM_003123	SPN	sialophorin
chr17_-_16875388	7.476	NM_012452	TNFRSF13B	tumor necrosis factor receptor superfamily, member 13B
chr17_-_29641094	7.463	NM_006495	EVI2B	ecotropic viral integration site 2B
chr6_-_41122025	7.448	NM_178174	TREML1	triggering receptor expressed on myeloid cells-like 1
chr1_-_207095198	7.419	NM_001193338 NM_001142473 NM_005449	FAIM3	Fas apoptotic inhibitory molecule 3
chr12_-_57873364	7.236	NM_001080157	ARHGAP9	Rho GTPase activating protein 9
chr22_-_37640287	7.229	NM_002872	RAC2	ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr15_+_81589240	7.225	NM_004513	IL16	interleukin 16
chr3_-_121379701	7.016		HCLS1	hematopoietic cell-specific Lyn substrate 1
chr3_-_121379757	6.978	NM_005335	HCLS1	hematopoietic cell-specific Lyn substrate 1
chr19_+_3178735	6.919	NM_003775	S1PR4	sphingosine-1-phosphate receptor 4
chr6_+_31553955	6.782	NM_205838 NM_205839	LST1	leukocyte specific transcript 1
chr22_-_37640187	6.781		RAC2	ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr3_-_46249787	6.771	NM_001295	CCR1	chemokine (C-C motif) receptor 1
chr1_+_203734283	6.768	NM_001136190 NM_017773	LAX1	lymphocyte transmembrane adaptor 1
chr1_-_36948423	6.609		CSF3R	colony stimulating factor 3 receptor (granulocyte)
chr16_+_29674564	6.597		SPN	sialophorin
chrX_+_128913881	6.511	NM_018990	SASH3	SAM and SH3 domain containing 3
chr7_+_106505876	6.495	NM_002649	PIK3CG	phosphoinositide-3-kinase, catalytic, gamma polypeptide
chr1_-_183559463	6.491		NCF2	neutrophil cytosolic factor 2
chr3_+_108541544	6.430	NM_016388	TRAT1	T cell receptor associated transmembrane adaptor 1
chr21_+_43823970	6.406	NM_001001895 NM_001243467 NM_018961	UBASH3A	ubiquitin associated and SH3 domain containing A
chr21_-_15918635	6.397	NM_022136	SAMSN1	SAM domain, SH3 domain and nuclear localization signals 1
chr22_+_37257004	6.303	NM_000631 NM_013416	NCF4	neutrophil cytosolic factor 4, 40kDa
chr17_-_29641068	6.217		EVI2B	ecotropic viral integration site 2B
chr1_+_111742946	6.210
chr9_-_117150217	6.207		AKNA	AT-hook transcription factor
chr11_-_111250156	6.194	NM_006235	POU2AF1	POU class 2 associating factor 1
chr6_-_31550065	6.192	NM_002341 NM_009588	LTB	lymphotoxin beta (TNF superfamily, member 3)
chr16_-_30393856	6.184		SEPT1	septin 1
chr2_-_175499275	6.179	NM_003387	WIPF1	WAS/WASL interacting protein family, member 1
chr1_+_158901336	6.146	NM_152501 NM_198928 NM_198929 NM_198930	PYHIN1	pyrin and HIN domain family, member 1
chrX_+_128913897	6.106		SASH3	SAM and SH3 domain containing 3
chr2_+_233925035	6.105	NM_001017915 NM_005541	INPP5D	inositol polyphosphate-5-phosphatase, 145kDa
chr11_+_63974190	6.075		FERMT3	fermitin family member 3
chr12_-_53600999	6.069	NM_000889	ITGB7	integrin, beta 7
chr17_-_38721701	6.042	NM_001838	CCR7	chemokine (C-C motif) receptor 7
chr1_+_111415721	5.996	NM_000560	CD53	CD53 molecule
chr3_+_111261039	5.985		CD96	CD96 molecule
chr7_-_45018650	5.978		MYO1G	myosin IG
chr11_-_111249902	5.966		POU2AF1	POU class 2 associating factor 1
chr7_-_3083346	5.931	NM_032415	CARD11	caspase recruitment domain family, member 11
chr19_+_49838673	5.929	NM_001040031 NM_001774	CD37	CD37 molecule
chr3_-_112693711	5.899	NM_138806 NM_138939 NM_138940 NM_170780	CD200R1	CD200 receptor 1
chr2_-_136873740	5.881	NM_001008540	CXCR4	chemokine (C-X-C motif) receptor 4
chr1_-_183560010	5.879	NM_001127651	NCF2	neutrophil cytosolic factor 2
chr2_+_233925104	5.862		INPP5D	inositol polyphosphate-5-phosphatase, 145kDa
chr1_-_150738255	5.847		CTSS	cathepsin S
chr17_-_29641087	5.841		EVI2B	ecotropic viral integration site 2B
chr1_+_111415791	5.823		CD53	CD53 molecule
chr10_-_6104113	5.815	NM_000417	IL2RA	interleukin 2 receptor, alpha
chr4_+_100737980	5.738	NM_014395	DAPP1	dual adaptor of phosphotyrosine and 3-phosphoinositides
chr7_-_45018677	5.719	NM_033054	MYO1G	myosin IG
chr13_-_46756326	5.678	NM_002298	LCP1	lymphocyte cytosolic protein 1 (L-plastin)
chr19_-_47128293	5.669	NM_000960	PTGIR	prostaglandin I2 (prostacyclin) receptor (IP)
chr3_+_111260925	5.654	NM_005816 NM_198196	CD96	CD96 molecule
chr4_-_153601085	5.564	NM_152680	TMEM154	transmembrane protein 154
chr16_-_30394133	5.491	NM_052838	SEPT1	septin 1
chr1_-_157746863	5.473	NM_030764	FCRL2	Fc receptor-like 2
chr19_+_17634109	5.458	NM_001098524 NM_173544	FAM129C	family with sequence similarity 129, member C
chr11_+_67171400	5.452	NM_198517	TBC1D10C	TBC1 domain family, member 10C
chr1_-_111743080	5.447
chr1_-_202129705	5.429		PTPN7	protein tyrosine phosphatase, non-receptor type 7
chr11_+_65407591	5.392	NM_153253	SIPA1	signal-induced proliferation-associated 1
chr5_-_176937337	5.363	NM_001144875 NM_001144876	DOK3	docking protein 3
chr19_+_36393381	5.359	NM_001007469 NM_014266	HCST	hematopoietic cell signal transducer
chr16_+_30484108	5.322
chr3_+_46395574	5.298		CCR2	chemokine (C-C motif) receptor 2
chr19_+_35940616	5.258	NM_005306	FFAR2	free fatty acid receptor 2
chr19_+_49838700	5.236		CD37	CD37 molecule
chr19_-_42636559	5.204	NM_001207025 NM_001207026 NM_001247994 NM_002698	POU2F2	POU class 2 homeobox 2
chr13_-_46756291	5.138		LCP1	lymphocyte cytosolic protein 1 (L-plastin)
chr10_+_49892860	5.120		WDFY4	WDFY family member 4
chr1_-_167059524	5.117	NM_005814	GPA33	glycoprotein A33 (transmembrane)
chr7_-_45018559	5.071		MYO1G	myosin IG
chr13_-_46756295	5.041		LCP1	lymphocyte cytosolic protein 1 (L-plastin)
chr2_+_182321618	5.000	NM_000885	ITGA4	integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
chr16_-_50715116	4.987		SNX20	sorting nexin 20
chr17_-_72619794	4.978	NM_181449	CD300E	CD300e molecule
chr4_+_102711833	4.975		BANK1	B-cell scaffold protein with ankyrin repeats 1
chr11_+_67171379	4.967		TBC1D10C	TBC1 domain family, member 10C
chr6_+_31554475	4.955	NM_205837	LST1	leukocyte specific transcript 1
chr19_+_42381189	4.946	NM_001783 NM_021601	CD79A	CD79a molecule, immunoglobulin-associated alpha
chr12_-_53601051	4.943		ITGB7	integrin, beta 7
chr22_+_37678565	4.894		CYTH4	cytohesin 4
chr11_+_60223281	4.816	NM_021950 NM_152866	MS4A1	membrane-spanning 4-domains, subfamily A, member 1
chr7_-_115670828	4.776	NM_001018058 NM_012252	TFEC	transcription factor EC
chr10_+_124320180	4.745	NM_004406 NM_007329 NM_017579	DMBT1	deleted in malignant brain tumors 1
chr1_+_192127591	4.735	NM_130782	RGS18	regulator of G-protein signaling 18
chr1_-_161039413	4.714		ARHGAP30	Rho GTPase activating protein 30
chr1_+_27668499	4.675		SYTL1	synaptotagmin-like 1
chr5_+_40841296	4.675	NM_032587	CARD6	caspase recruitment domain family, member 6
chr1_-_161039649	4.670		ARHGAP30	Rho GTPase activating protein 30
chr1_-_36948914	4.655	NM_000760 NM_156039 NM_172313	CSF3R	colony stimulating factor 3 receptor (granulocyte)
chr22_+_23165273	4.651
chr15_-_80263460	4.640	NM_001114735 NM_004049	BCL2A1	BCL2-related protein A1
chr19_+_49838646	4.638		CD37	CD37 molecule
chr1_-_162381805	4.614	NM_053282	SH2D1B	SH2 domain containing 1B
chr20_-_35274557	4.570	NM_032214 NM_175077	SLA2	Src-like-adaptor 2
chr1_-_150738232	4.531		CTSS	cathepsin S
chr14_+_21249209	4.530	NM_005615	RNASE6	ribonuclease, RNase A family, k6
chr21_-_46340874	4.517	NM_000211	ITGB2	integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr11_-_3862137	4.477		RHOG	ras homolog gene family, member G (rho G)
chr12_+_9142136	4.405	NM_005810	KLRG1	killer cell lectin-like receptor subfamily G, member 1
chr6_+_167536240	4.387	NM_031409	CCR6	chemokine (C-C motif) receptor 6
chr6_-_130536417	4.384	NM_152552	SAMD3	sterile alpha motif domain containing 3
chr22_+_37678423	4.374	NM_013385	CYTH4	cytohesin 4
chr22_-_19512859	4.363	NM_001130861 NM_003277	CLDN5	claudin 5
chr18_-_53177999	4.349	NM_001243231	TCF4	transcription factor 4
chr11_-_3862183	4.347	NM_001665	RHOG	ras homolog gene family, member G (rho G)
chr2_+_204732509	4.305	NM_001037631 NM_005214	CTLA4	cytotoxic T-lymphocyte-associated protein 4
chr11_-_104893894	4.299	NM_001136109 NM_001136110 NM_001136112 NM_004347	CASP5	caspase 5, apoptosis-related cysteine peptidase
chr10_+_26727651	4.279		APBB1IP	amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
chr3_+_122334461	4.237	NM_152615	PARP15	poly (ADP-ribose) polymerase family, member 15
chr15_-_40599872	4.232		PLCB2	phospholipase C, beta 2
chr17_-_29648631	4.198	NM_001003927 NM_014210	EVI2A	ecotropic viral integration site 2A
chr14_-_69446038	4.197	NM_001102 NM_001130004 NM_001130005	ACTN1	actinin, alpha 1
chr17_-_42466840	4.169	NM_000419	ITGA2B	integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
chr2_+_143886898	4.107	NM_018460	ARHGAP15	Rho GTPase activating protein 15
chr1_-_161039586	4.067		ARHGAP30	Rho GTPase activating protein 30
chr11_-_118123001	4.056	NM_198275	MPZL3	myelin protein zero-like 3
chrX_-_47489243	4.013	NM_001145252	CFP	complement factor properdin
chr12_-_92539614	3.998	NM_001731	BTG1	B-cell translocation gene 1, anti-proliferative
chr15_-_40600025	3.978		PLCB2	phospholipase C, beta 2
chr6_-_159466019	3.975	NM_054114 NM_138810 NM_152133	TAGAP	T-cell activation RhoGTPase activating protein
chr6_+_153019029	3.974	NM_025107	MYCT1	myc target 1
chr19_+_16999871	3.969		F2RL3	coagulation factor II (thrombin) receptor-like 3
chr14_-_107179043	3.967		IGHA1	immunoglobulin heavy constant alpha 1
chr19_-_11689591	3.963	NM_001111034	ACP5	acid phosphatase 5, tartrate resistant
chr19_-_6481765	3.958	NM_024898	DENND1C	DENN/MADD domain containing 1C
chr22_+_37678519	3.955		CYTH4	cytohesin 4
chr3_-_150920946	3.954	NM_013308	GPR171	G protein-coupled receptor 171
chr1_-_153518265	3.946	NM_002961 NM_019554	S100A4	S100 calcium binding protein A4
chr4_+_102711763	3.917	NM_001127507 NM_017935	BANK1	B-cell scaffold protein with ankyrin repeats 1
chr1_+_158801105	3.916	NM_002432	MNDA	myeloid cell nuclear differentiation antigen
chr7_+_142829169	3.912	NM_002652	PIP	prolactin-induced protein
chr7_-_115670774	3.897		TFEC	transcription factor EC
chr17_+_43299277	3.883	NM_005892	FMNL1	formin-like 1
chr5_-_39219578	3.860	NM_001465 NM_199335	FYB	FYN binding protein
chr1_-_150738292	3.853	NM_001199739 NM_004079	CTSS	cathepsin S
chr3_+_46395224	3.851	NM_001123041 NM_001123396	CCR2	chemokine (C-C motif) receptor 2
chr11_-_61129462	3.849	NM_001161454 NM_153611	CYBASC3	cytochrome b, ascorbate dependent 3
chr4_-_48136245	3.844	NM_003328	TXK	TXK tyrosine kinase
chr6_+_35265654	3.842		DEF6	differentially expressed in FDCP 6 homolog (mouse)
chr10_-_81320141	3.837	NM_001098668	SFTPA1 SFTPA2	surfactant protein A1 surfactant protein A2
chr8_+_74903563	3.829	NM_001195797 NM_015364	LY96	lymphocyte antigen 96
chr10_+_49893514	3.824	NM_020945	WDFY4	WDFY family member 4
chr6_-_42016383	3.822		CCND3	cyclin D3
chr22_+_23134980	3.769
chr14_-_24036939	3.765		AP1G2	adaptor-related protein complex 1, gamma 2 subunit
chr4_-_5021095	3.744	NM_018659	CYTL1	cytokine-like 1
chr10_+_26727692	3.713		APBB1IP	amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
chr1_-_111743297	3.698		DENND2D	DENN/MADD domain containing 2D
chr5_-_66492574	3.668	NM_005582	CD180	CD180 molecule
chr9_+_273025	3.668	NM_001190458 NM_001193536	DOCK8	dedicator of cytokinesis 8
chr5_-_169724614	3.665		LCP2	lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr14_-_106733392	3.653		IGHG1 IGHG3	immunoglobulin heavy constant gamma 1 (G1m marker) immunoglobulin heavy constant gamma 3 (G3m marker)
chr10_+_81370694	3.633	NM_001093770 NM_001164644 NM_001164645 NM_001164646 NM_001164647 NM_005411	SFTPA1	surfactant protein A1
chr1_+_206730497	3.632		RASSF5	Ras association (RalGDS/AF-6) domain family member 5
chrX_+_48542193	3.612		WAS	Wiskott-Aldrich syndrome (eczema-thrombocytopenia)
chr8_+_27182995	3.612	NM_173176	PTK2B	PTK2B protein tyrosine kinase 2 beta
chr11_+_63974144	3.601	NM_031471 NM_178443	FERMT3	fermitin family member 3
chr10_+_114154522	3.600		ACSL5	acyl-CoA synthetase long-chain family member 5

Gene overrepresentation in process category:

Enrichment	P-value	GO Accession	GO Term
4.25	6.75e-68	GO:0002376	immune system process
4.73	2.65e-49	GO:0006955	immune response
4.79	1.46e-46	GO:0002682	regulation of immune system process
5.77	3.99e-43	GO:0050776	regulation of immune response
5.01	9.89e-36	GO:0001775	cell activation
2.68	8.12e-34	GO:0048583	regulation of response to stimulus
5.16	8.68e-34	GO:0002684	positive regulation of immune system process
6.68	1.11e-30	GO:0045321	leukocyte activation
3.44	1.51e-28	GO:0009611	response to wounding
3.52	4.05e-27	GO:0006952	defense response
6.30	4.69e-27	GO:0002694	regulation of leukocyte activation
1.99	3.82e-26	GO:0007165	signal transduction
6.06	4.40e-26	GO:0050865	regulation of cell activation
1.62	4.75e-26	GO:0050896	response to stimulus
6.46	1.29e-25	GO:0051249	regulation of lymphocyte activation
6.69	2.52e-24	GO:0046649	lymphocyte activation
5.39	1.16e-23	GO:0050778	positive regulation of immune response
1.85	2.13e-22	GO:0023052	signaling
1.79	2.63e-22	GO:0051716	cellular response to stimulus
6.37	1.11e-20	GO:0002764	immune response-regulating signaling pathway
6.49	4.96e-20	GO:0051251	positive regulation of lymphocyte activation
8.26	9.54e-20	GO:0002768	immune response-regulating cell surface receptor signaling pathway
6.19	1.23e-19	GO:0002696	positive regulation of leukocyte activation
6.09	2.58e-19	GO:0050867	positive regulation of cell activation
6.08	2.53e-18	GO:0002757	immune response-activating signal transduction
2.03	4.52e-18	GO:0006950	response to stress
6.12	6.18e-18	GO:0050863	regulation of T cell activation
4.75	1.64e-17	GO:0006954	inflammatory response
8.26	2.96e-17	GO:0050851	antigen receptor-mediated signaling pathway
7.85	4.11e-17	GO:0002429	immune response-activating cell surface receptor signaling pathway
7.62	1.12e-16	GO:0070663	regulation of leukocyte proliferation
7.17	2.43e-16	GO:0042110	T cell activation
7.68	3.36e-16	GO:0050670	regulation of lymphocyte proliferation
5.12	4.03e-16	GO:0002253	activation of immune response
7.60	4.67e-16	GO:0032944	regulation of mononuclear cell proliferation
6.47	7.45e-16	GO:0050870	positive regulation of T cell activation
1.39	1.15e-15	GO:0065007	biological regulation
6.07	2.32e-15	GO:0002697	regulation of immune effector process
1.41	2.86e-15	GO:0050789	regulation of biological process
4.11	2.30e-14	GO:0031347	regulation of defense response
2.79	5.10e-14	GO:0048584	positive regulation of response to stimulus
7.30	8.67e-14	GO:0030098	lymphocyte differentiation
2.08	9.40e-14	GO:0007166	cell surface receptor linked signaling pathway
4.35	1.13e-13	GO:0001817	regulation of cytokine production
3.17	1.48e-13	GO:0050878	regulation of body fluid levels
3.34	1.83e-13	GO:0007599	hemostasis
3.10	2.52e-13	GO:0042060	wound healing
6.19	3.20e-13	GO:0002521	leukocyte differentiation
3.31	5.31e-13	GO:0007596	blood coagulation
3.31	5.31e-13	GO:0050817	coagulation
4.47	1.06e-12	GO:0030097	hemopoiesis
9.08	1.13e-12	GO:0050864	regulation of B cell activation
2.62	2.00e-12	GO:0040011	locomotion
1.40	2.23e-12	GO:0050794	regulation of cellular process
4.19	2.33e-12	GO:0048534	hemopoietic or lymphoid organ development
8.79	2.53e-12	GO:0030217	T cell differentiation
3.98	7.91e-12	GO:0002520	immune system development
7.80	1.12e-11	GO:0050671	positive regulation of lymphocyte proliferation
7.70	1.56e-11	GO:0032946	positive regulation of mononuclear cell proliferation
7.59	2.17e-11	GO:0070665	positive regulation of leukocyte proliferation
11.08	4.64e-11	GO:0030888	regulation of B cell proliferation
5.19	6.32e-11	GO:0050900	leukocyte migration
3.05	6.73e-11	GO:0080134	regulation of response to stress
1.74	1.88e-10	GO:0048518	positive regulation of biological process
4.17	2.96e-10	GO:0030168	platelet activation
2.97	5.85e-10	GO:0006935	chemotaxis
2.97	5.85e-10	GO:0042330	taxis
5.06	8.52e-10	GO:0002252	immune effector process
9.57	8.81e-10	GO:0045621	positive regulation of lymphocyte differentiation
15.64	1.41e-09	GO:0050853	B cell receptor signaling pathway
9.91	2.29e-09	GO:0045582	positive regulation of T cell differentiation
6.93	2.31e-09	GO:0002699	positive regulation of immune effector process
8.41	2.41e-09	GO:0045580	regulation of T cell differentiation
7.71	3.35e-09	GO:0045619	regulation of lymphocyte differentiation
7.13	1.61e-08	GO:0002703	regulation of leukocyte mediated immunity
2.26	1.68e-08	GO:0042127	regulation of cell proliferation
6.60	2.17e-08	GO:0050852	T cell receptor signaling pathway
6.43	3.68e-08	GO:0042035	regulation of cytokine biosynthetic process
9.06	5.42e-08	GO:0050871	positive regulation of B cell activation
3.01	5.59e-08	GO:0051707	response to other organism
2.27	7.26e-08	GO:0051704	multi-organism process
6.54	8.73e-08	GO:0042113	B cell activation
4.33	1.07e-07	GO:0031349	positive regulation of defense response
18.57	1.13e-07	GO:0042100	B cell proliferation
1.95	1.36e-07	GO:0009966	regulation of signal transduction
2.17	1.82e-07	GO:0009605	response to external stimulus
2.62	3.40e-07	GO:0006928	cellular component movement
14.57	3.43e-07	GO:0045058	T cell selection
6.46	3.50e-07	GO:0042129	regulation of T cell proliferation
2.69	4.46e-07	GO:0009607	response to biotic stimulus
10.61	6.08e-07	GO:0001910	regulation of leukocyte mediated cytotoxicity
7.20	6.14e-07	GO:0060326	cell chemotaxis
1.93	7.33e-07	GO:0035556	intracellular signal transduction
7.08	8.28e-07	GO:0002695	negative regulation of leukocyte activation
7.58	9.95e-07	GO:0042102	positive regulation of T cell proliferation
3.52	2.22e-06	GO:0032101	regulation of response to external stimulus
9.59	2.52e-06	GO:0031341	regulation of cell killing
7.14	2.53e-06	GO:0042108	positive regulation of cytokine biosynthetic process
4.91	2.69e-06	GO:0050727	regulation of inflammatory response
8.47	3.07e-06	GO:0046634	regulation of alpha-beta T cell activation
5.11	3.18e-06	GO:0002683	negative regulation of immune system process
6.50	3.34e-06	GO:0050866	negative regulation of cell activation
1.80	3.59e-06	GO:0023051	regulation of signaling
2.89	3.72e-06	GO:0045087	innate immune response
6.39	4.33e-06	GO:0031294	lymphocyte costimulation
6.39	4.33e-06	GO:0031295	T cell costimulation
6.88	4.53e-06	GO:0006968	cellular defense response
9.01	5.89e-06	GO:0046651	lymphocyte proliferation
6.63	7.88e-06	GO:0002706	regulation of lymphocyte mediated immunity
2.52	8.79e-06	GO:0008284	positive regulation of cell proliferation
1.65	9.91e-06	GO:0065008	regulation of biological quality
7.08	1.04e-05	GO:0051250	negative regulation of lymphocyte activation
9.73	1.04e-05	GO:0030890	positive regulation of B cell proliferation
8.49	1.29e-05	GO:0032943	mononuclear cell proliferation
1.60	1.51e-05	GO:0048522	positive regulation of cellular process
7.49	1.72e-05	GO:0030595	leukocyte chemotaxis
8.26	1.86e-05	GO:0070661	leukocyte proliferation
2.67	2.29e-05	GO:0016477	cell migration
1.86	2.46e-05	GO:0051239	regulation of multicellular organismal process
4.30	3.24e-05	GO:0045089	positive regulation of innate immune response
5.26	3.33e-05	GO:0048872	homeostasis of number of cells
5.99	3.60e-05	GO:0002831	regulation of response to biotic stimulus
3.66	4.11e-05	GO:0045088	regulation of innate immune response
6.19	6.87e-05	GO:0002822	regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
2.82	7.54e-05	GO:0045597	positive regulation of cell differentiation
8.26	7.80e-05	GO:0032663	regulation of interleukin-2 production
6.08	8.77e-05	GO:0002819	regulation of adaptive immune response
3.72	1.11e-04	GO:0009615	response to virus
4.84	1.24e-04	GO:0002443	leukocyte mediated immunity
6.44	1.28e-04	GO:0001816	cytokine production
5.02	1.80e-04	GO:0043900	regulation of multi-organism process
2.48	1.81e-04	GO:0051094	positive regulation of developmental process
18.57	2.32e-04	GO:0043368	positive T cell selection
11.65	2.51e-04	GO:0050869	negative regulation of B cell activation
6.60	3.05e-04	GO:0002274	myeloid leukocyte activation
2.43	3.28e-04	GO:0048870	cell motility
2.43	3.28e-04	GO:0051674	localization of cell
2.60	3.63e-04	GO:0051056	regulation of small GTPase mediated signal transduction
4.72	4.41e-04	GO:0050730	regulation of peptidyl-tyrosine phosphorylation
7.99	4.68e-04	GO:0046635	positive regulation of alpha-beta T cell activation
4.39	5.58e-04	GO:0032103	positive regulation of response to external stimulus
1.53	6.16e-04	GO:0048519	negative regulation of biological process
6.19	6.61e-04	GO:0002263	cell activation involved in immune response
6.19	6.61e-04	GO:0002366	leukocyte activation involved in immune response
16.51	6.71e-04	GO:0030889	negative regulation of B cell proliferation
2.03	8.77e-04	GO:0007155	cell adhesion
2.03	8.77e-04	GO:0022610	biological adhesion
2.71	1.03e-03	GO:0034097	response to cytokine stimulus
1.14	1.08e-03	GO:0009987	cellular process
8.26	1.39e-03	GO:0007159	leukocyte cell-cell adhesion
8.26	1.39e-03	GO:0046637	regulation of alpha-beta T cell differentiation
2.87	1.87e-03	GO:0030036	actin cytoskeleton organization
3.62	2.47e-03	GO:0001819	positive regulation of cytokine production
2.12	2.87e-03	GO:0071822	protein complex subunit organization
2.42	2.87e-03	GO:0007264	small GTPase mediated signal transduction
2.80	3.07e-03	GO:0009617	response to bacterium
1.97	3.31e-03	GO:2000026	regulation of multicellular organismal development
5.92	3.33e-03	GO:0032649	regulation of interferon-gamma production
1.51	3.34e-03	GO:0042221	response to chemical stimulus
13.51	3.44e-03	GO:0045061	thymic T cell selection
6.52	3.85e-03	GO:0002705	positive regulation of leukocyte mediated immunity
6.52	3.85e-03	GO:0002708	positive regulation of lymphocyte mediated immunity
8.61	4.07e-03	GO:0001912	positive regulation of leukocyte mediated cytotoxicity
10.20	4.85e-03	GO:0043370	regulation of CD4-positive, alpha-beta T cell differentiation
10.20	4.85e-03	GO:2000514	regulation of CD4-positive, alpha-beta T cell activation
6.35	5.00e-03	GO:0002687	positive regulation of leukocyte migration
8.26	5.90e-03	GO:0002637	regulation of immunoglobulin production
5.56	6.50e-03	GO:0050688	regulation of defense response to virus
6.97	6.93e-03	GO:0070664	negative regulation of leukocyte proliferation
9.63	7.66e-03	GO:0030593	neutrophil chemotaxis
7.92	8.36e-03	GO:0002763	positive regulation of myeloid leukocyte differentiation
3.31	9.49e-03	GO:0002237	response to molecule of bacterial origin
5.90	1.04e-02	GO:0045639	positive regulation of myeloid cell differentiation
4.18	1.14e-02	GO:0019080	viral genome expression
4.18	1.14e-02	GO:0019083	viral transcription
7.62	1.17e-02	GO:0031343	positive regulation of cell killing
9.12	1.17e-02	GO:0045076	regulation of interleukin-2 biosynthetic process
11.43	1.19e-02	GO:0045086	positive regulation of interleukin-2 biosynthetic process
3.04	1.21e-02	GO:0035270	endocrine system development
3.38	1.28e-02	GO:0019058	viral infectious cycle
4.72	1.45e-02	GO:0050920	regulation of chemotaxis
3.10	1.54e-02	GO:0030155	regulation of cell adhesion
7.34	1.60e-02	GO:0032655	regulation of interleukin-12 production
2.67	1.73e-02	GO:0051241	negative regulation of multicellular organismal process
4.03	1.75e-02	GO:0006415	translational termination
2.12	1.81e-02	GO:0048585	negative regulation of response to stimulus
3.79	1.83e-02	GO:0006414	translational elongation
2.79	1.88e-02	GO:0071345	cellular response to cytokine stimulus
5.50	2.01e-02	GO:0050921	positive regulation of chemotaxis
10.61	2.02e-02	GO:0046640	regulation of alpha-beta T cell proliferation
3.14	2.13e-02	GO:0040017	positive regulation of locomotion
7.08	2.16e-02	GO:0033077	T cell differentiation in thymus
7.08	2.16e-02	GO:0051607	defense response to virus
1.48	2.35e-02	GO:0048523	negative regulation of cellular process
5.38	2.48e-02	GO:0002700	regulation of production of molecular mediator of immune response
6.02	2.56e-02	GO:0018108	peptidyl-tyrosine phosphorylation
1.73	2.63e-02	GO:0042981	regulation of apoptosis
1.78	2.71e-02	GO:0050793	regulation of developmental process
2.48	3.04e-02	GO:0030029	actin filament-based process
1.74	3.10e-02	GO:0032879	regulation of localization
9.91	3.24e-02	GO:0050854	regulation of antigen receptor-mediated signaling pathway
2.20	3.29e-02	GO:0007243	intracellular protein kinase cascade
2.20	3.29e-02	GO:0023014	signal transduction via phosphorylation event
3.04	3.42e-02	GO:0051272	positive regulation of cellular component movement
1.71	3.44e-02	GO:0043067	regulation of programmed cell death
7.88	3.56e-02	GO:0046638	positive regulation of alpha-beta T cell differentiation
7.88	3.56e-02	GO:0050848	regulation of calcium-mediated signaling
3.26	3.66e-02	GO:0032496	response to lipopolysaccharide
5.16	3.70e-02	GO:0002685	regulation of leukocyte migration
5.16	3.70e-02	GO:0050729	positive regulation of inflammatory response
6.60	3.78e-02	GO:0032945	negative regulation of mononuclear cell proliferation
6.60	3.78e-02	GO:0050672	negative regulation of lymphocyte proliferation
5.72	4.06e-02	GO:0018212	peptidyl-tyrosine modification
5.72	4.06e-02	GO:0050868	negative regulation of T cell activation
3.08	4.78e-02	GO:0030335	positive regulation of cell migration
3.08	4.78e-02	GO:2000147	positive regulation of cell motility
3.93	4.89e-02	GO:0045637	regulation of myeloid cell differentiation
6.39	4.92e-02	GO:0002690	positive regulation of leukocyte chemotaxis
3.69	4.98e-02	GO:0002218	activation of innate immune response

Gene overrepresentation in compartment category:

Enrichment	P-value	GO Accession	GO Term
1.82	3.00e-26	GO:0005886	plasma membrane
1.81	5.97e-26	GO:0071944	cell periphery
1.36	7.15e-14	GO:0016020	membrane
1.90	1.92e-13	GO:0044459	plasma membrane part
5.56	1.02e-12	GO:0009897	external side of plasma membrane
2.14	7.25e-11	GO:0005887	integral to plasma membrane
2.10	2.29e-10	GO:0031226	intrinsic to plasma membrane
1.36	1.74e-09	GO:0044425	membrane part
18.57	1.41e-08	GO:0042101	T cell receptor complex
2.99	2.40e-08	GO:0009986	cell surface
1.35	8.35e-07	GO:0016021	integral to membrane
4.25	1.05e-06	GO:0043235	receptor complex
1.34	1.56e-06	GO:0031224	intrinsic to membrane
1.90	7.43e-04	GO:0005615	extracellular space
1.51	9.75e-04	GO:0005829	cytosol
11.43	1.50e-03	GO:0001772	immunological synapse
1.81	8.33e-03	GO:0031988	membrane-bounded vesicle
8.74	9.38e-03	GO:0045335	phagocytic vesicle
4.02	9.96e-03	GO:0022626	cytosolic ribosome
1.81	1.02e-02	GO:0016023	cytoplasmic membrane-bounded vesicle
3.50	1.13e-02	GO:0005925	focal adhesion
2.93	1.13e-02	GO:0044445	cytosolic part
1.77	1.27e-02	GO:0031410	cytoplasmic vesicle
1.75	1.53e-02	GO:0031982	vesicle
24.76	1.71e-02	GO:0019814	immunoglobulin complex
24.76	1.71e-02	GO:0019815	B cell receptor complex
24.76	1.71e-02	GO:0042105	alpha-beta T cell receptor complex
3.33	1.96e-02	GO:0005924	cell-substrate adherens junction
2.85	2.69e-02	GO:0045121	membrane raft
1.42	2.97e-02	GO:0005576	extracellular region
3.21	2.97e-02	GO:0030055	cell-substrate junction
5.98	3.19e-02	GO:0008305	integrin complex

Gene overrepresentation in function category:

Enrichment	P-value	GO Accession	GO Term
2.03	3.41e-16	GO:0004871	signal transducer activity
2.03	3.41e-16	GO:0060089	molecular transducer activity
2.07	9.44e-14	GO:0004872	receptor activity
1.33	5.99e-10	GO:0005515	protein binding
3.96	2.21e-08	GO:0005125	cytokine activity
7.77	3.41e-08	GO:0042379	chemokine receptor binding
8.08	7.16e-08	GO:0008009	chemokine activity
3.85	3.58e-07	GO:0005126	cytokine receptor binding
8.26	8.76e-07	GO:0004715	non-membrane spanning protein tyrosine kinase activity
8.05	1.25e-06	GO:0003823	antigen binding
3.52	5.33e-06	GO:0005529	sugar binding
2.51	5.96e-06	GO:0030695	GTPase regulator activity
2.44	1.33e-05	GO:0060589	nucleoside-triphosphatase regulator activity
1.92	2.01e-05	GO:0005102	receptor binding
2.98	3.89e-05	GO:0005096	GTPase activator activity
5.37	2.54e-04	GO:0035591	signaling adaptor activity
2.42	2.94e-04	GO:0008047	enzyme activator activity
2.44	3.26e-04	GO:0030246	carbohydrate binding
5.56	1.29e-03	GO:0005070	SH3/SH2 adaptor activity
1.78	2.39e-03	GO:0030234	enzyme regulator activity
3.67	2.82e-03	GO:0019955	cytokine binding
1.65	2.96e-03	GO:0004888	transmembrane receptor activity
2.56	3.23e-03	GO:0032403	protein complex binding
3.60	3.58e-03	GO:0017124	SH3 domain binding
7.54	9.78e-03	GO:0001608	nucleotide receptor activity, G-protein coupled
7.54	9.78e-03	GO:0045028	purinergic nucleotide receptor activity, G-protein coupled
3.33	9.85e-03	GO:0030674	protein binding, bridging
1.82	9.94e-03	GO:0019899	enzyme binding
3.12	2.22e-02	GO:0060090	binding, bridging
24.76	2.69e-02	GO:0004911	interleukin-2 receptor activity
24.76	2.69e-02	GO:0019976	interleukin-2 binding
2.74	2.90e-02	GO:0001664	G-protein-coupled receptor binding
7.43	4.18e-02	GO:0001637	G-protein chemoattractant receptor activity
7.43	4.18e-02	GO:0004950	chemokine receptor activity