Motif ID: FOSL2.p2

Z-value: 2.486


Transcription factors associated with FOSL2.p2:

Gene SymbolEntrez IDGene Name
FOSL2 2355 FOS-like antigen 2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
FOSL2hg19_v1_chr2_+_28615771_28615794-0.057.8e-01Click!


Activity profile for motif FOSL2.p2.

activity profile for motif FOSL2.p2


Sorted Z-values histogram for motif FOSL2.p2

Sorted Z-values for motif FOSL2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of FOSL2.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr22_+_23040394 19.818 IGL@
immunoglobulin lambda locus
chr2_-_89292396 17.226 IGKC
immunoglobulin kappa constant
chr2_-_89513056 16.964 IGKC
immunoglobulin kappa constant
chr2_-_89442551 15.739 IGKC
IGK@
immunoglobulin kappa constant
immunoglobulin kappa locus
chr22_+_22735134 14.744 CYAT1
immunoglobulin lambda light chain-like
chr22_+_22735207 13.523 IGLJ3
immunoglobulin lambda joining 3
chr22_+_23063107 12.857 IGLJ3
immunoglobulin lambda joining 3
chr22_+_22758538 12.809


chr22_+_22735202 12.484


chr2_-_89619820 11.605 IGKC
immunoglobulin kappa constant
chr22_+_22723972 11.518


chr22_+_22569155 11.261


chr22_+_23165273 11.182


chr17_-_38721701 10.535 NM_001838
CCR7
chemokine (C-C motif) receptor 7
chr7_+_73245192 9.918 NM_001305
CLDN4
claudin 4
chr2_+_90077732 9.045


chr16_+_31366529 8.865 ITGAX
integrin, alpha X (complement component 3 receptor 4 subunit)
chr22_+_23029175 8.317 IGLV3-25
immunoglobulin lambda variable 3-25
chr4_-_71532341 8.268 NM_144646
IGJ
immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
chr16_+_31366468 8.105 NM_000887
ITGAX
integrin, alpha X (complement component 3 receptor 4 subunit)
chr16_+_31366519 7.653 ITGAX
integrin, alpha X (complement component 3 receptor 4 subunit)
chr22_+_23154240 7.588


chr22_+_22712091 6.929 IGLV1-44
IGL@
immunoglobulin lambda variable 1-44
immunoglobulin lambda locus
chr22_+_22676814 6.679


chr17_-_39768939 6.394 NM_005557
KRT16
keratin 16
chr1_+_209929378 6.054 NM_025228
TRAF3IP3
TRAF3 interacting protein 3
chr1_-_45272956 6.048 NM_001013632
TCTEX1D4
Tctex1 domain containing 4
chr2_+_90211704 6.008


chr2_+_113875469 6.002 NM_000577
NM_173841
NM_173843
IL1RN


interleukin 1 receptor antagonist


chr4_-_71532206 5.931 IGJ
immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
chr20_+_44637539 5.822 NM_004994
MMP9
matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
chr16_+_28996369 5.491 NM_001014987
NM_001014988
NM_014387
LAT


linker for activation of T cells


chr2_-_85895863 5.438 NM_000542
NM_198843
SFTPB

surfactant protein B

chr4_+_74606222 5.412 NM_000584
IL8
interleukin 8
chr14_-_94854910 5.395 SERPINA1
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chr2_+_98330030 5.391 NM_001079
ZAP70
zeta-chain (TCR) associated protein kinase 70kDa
chr14_-_94855120 5.347 NM_000295
SERPINA1
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chr22_+_22764094 5.271


chr14_-_107179043 5.150 IGHA1
immunoglobulin heavy constant alpha 1
chr1_+_160709038 5.079 NM_021181
SLAMF7
SLAM family member 7
chr19_-_6670598 5.049 NM_003807
NM_172014
TNFSF14

tumor necrosis factor (ligand) superfamily, member 14

chrX_+_115567746 4.975 NM_007231
SLC6A14
solute carrier family 6 (amino acid transporter), member 14
chr22_+_23229959 4.932 NM_001178126
IGLL5
IGLC1
immunoglobulin lambda-like polypeptide 5
immunoglobulin lambda constant 1 (Mcg marker)
chr19_-_11688441 4.849 ACP5
acid phosphatase 5, tartrate resistant
chr1_-_108231122 4.806 NM_001079874
VAV3
vav 3 guanine nucleotide exchange factor
chr12_-_10282680 4.726 NM_022570
NM_197947
NM_197948
NM_197949
NM_197950
NM_197954
CLEC7A





C-type lectin domain family 7, member A





chr18_+_21452981 4.653 NM_000227
NM_001127718
LAMA3

laminin, alpha 3

chrX_-_154563735 4.515 NM_001289
CLIC2
chloride intracellular channel 2
chr2_+_120189342 4.491 NM_183240
TMEM37
transmembrane protein 37
chr1_-_117753476 4.479 NM_001253850
NM_024626
VTCN1

V-set domain containing T cell activation inhibitor 1

chr11_-_118213321 4.464 NM_000732
NM_001040651
CD3D

CD3d molecule, delta (CD3-TCR complex)

chr14_-_25103365 4.454 NM_004131
GZMB
granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
chr2_+_89185055 4.444


chr11_+_60739114 4.401 NM_006725
CD6
CD6 molecule
chr19_-_11688484 4.384 ACP5
acid phosphatase 5, tartrate resistant
chr5_+_35856990 4.341 NM_002185
IL7R
interleukin 7 receptor
chr11_-_102745666 4.335 NM_002426
MMP12
matrix metallopeptidase 12 (macrophage elastase)
chr15_+_41136178 4.316 NM_003710
NM_181642
SPINT1

serine peptidase inhibitor, Kunitz type 1

chr12_-_49259549 4.314 NM_014470
RND1
Rho family GTPase 1
chr11_+_62037629 4.314 NM_002411
SCGB2A2
secretoglobin, family 2A, member 2
chr4_-_39033981 4.243 NM_024943
TMEM156
transmembrane protein 156
chr11_-_102668822 4.236 MMP1
matrix metallopeptidase 1 (interstitial collagenase)
chr1_-_153521717 4.084 NM_002960
S100A3
S100 calcium binding protein A3
chr3_-_58200397 4.012 NM_004944
DNASE1L3
deoxyribonuclease I-like 3
chr22_+_23213671 4.004 IGLV4-3
immunoglobulin lambda variable 4-3
chr8_+_87111132 3.968 NM_152565
ATP6V0D2
ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2
chr6_-_149806116 3.963 NM_207360
ZC3H12D
zinc finger CCCH-type containing 12D
chr7_+_26331611 3.926 SNX10
sorting nexin 10
chr14_-_94849552 3.891 SERPINA1
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chr22_+_22550159 3.863 IGLV6-57
immunoglobulin lambda variable 6-57
chr12_-_15114495 3.785 NM_001175
ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
chr19_-_44285012 3.781 KCNN4
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
chr10_-_81708860 3.776 NM_003019
SFTPD
surfactant protein D
chr19_-_11688508 3.755 NM_001611
ACP5
acid phosphatase 5, tartrate resistant
chr16_+_57392694 3.725 NM_002990
CCL22
chemokine (C-C motif) ligand 22
chr10_-_95360959 3.711 NM_006744
RBP4
retinol binding protein 4, plasma
chr6_-_30712294 3.692 NM_003897
IER3
immediate early response 3
chr16_+_28996146 3.691 NM_001014989
LAT
linker for activation of T cells
chr19_+_55128601 3.686 NM_006669
LILRB1
leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1
chr22_+_23010757 3.653


chr22_+_23134980 3.636


chr15_+_41062158 3.566 NM_001130448
C15orf62
chromosome 15 open reading frame 62
chr15_+_41136622 3.565 NM_001032367
SPINT1
serine peptidase inhibitor, Kunitz type 1
chr16_+_27438578 3.544 NM_021798
IL21R
interleukin 21 receptor
chr5_-_141061749 3.537 ARAP3
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
chr7_+_30960914 3.529 NM_001185060
NM_001185061
NM_001185062
AQP1


aquaporin 1 (Colton blood group)


chr15_-_80263460 3.525 NM_001114735
NM_004049
BCL2A1

BCL2-related protein A1

chr17_-_34207308 3.520 NM_002985
CCL5
chemokine (C-C motif) ligand 5
chr16_+_1306272 3.503 NM_012217
TPSD1
tryptase delta 1
chr19_-_44285407 3.491 NM_002250
KCNN4
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
chr6_+_33043702 3.425 NM_002121
HLA-DPB1
major histocompatibility complex, class II, DP beta 1
chr1_-_160832466 3.424 NM_001166663
NM_001166664
NM_016382
CD244


CD244 molecule, natural killer cell receptor 2B4


chr5_-_54281345 3.330 NM_001135604
NM_007036
ESM1

endothelial cell-specific molecule 1

chr3_-_121379701 3.288 HCLS1
hematopoietic cell-specific Lyn substrate 1
chr1_+_160765927 3.283 NM_001033667
NM_002348
LY9

lymphocyte antigen 9

chr11_+_118754474 3.280 NM_001716
CXCR5
chemokine (C-X-C motif) receptor 5
chr1_-_152009490 3.247 NM_005620
S100A11
S100 calcium binding protein A11
chrX_+_99899162 3.203 NM_014467
SRPX2
sushi-repeat containing protein, X-linked 2
chr10_+_17270257 3.175 NM_003380
VIM
vimentin
chr15_+_89182038 3.168 NM_002201
ISG20
interferon stimulated exonuclease gene 20kDa
chr19_+_51645556 3.158 NM_014385
NM_016543
SIGLEC7

sialic acid binding Ig-like lectin 7

chr7_+_94024201 3.133 COL1A2
collagen, type I, alpha 2
chr3_-_121379757 3.122 NM_005335
HCLS1
hematopoietic cell-specific Lyn substrate 1
chrX_+_115567820 3.094 SLC6A14
solute carrier family 6 (amino acid transporter), member 14
chr8_-_82395401 3.087 NM_001442
FABP4
fatty acid binding protein 4, adipocyte
chr19_-_51875790 3.085 NM_005601
NKG7
natural killer cell group 7 sequence
chr5_-_141061798 3.070 NM_022481
ARAP3
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
chr20_-_34195409 3.066 FER1L4
fer-1-like 4 (C. elegans) pseudogene
chr19_-_44174271 3.062 PLAUR
plasminogen activator, urokinase receptor
chr14_-_106641585 3.054 IGHV4-31
IGHA1
IGHA2
IGHG1
immunoglobulin heavy variable 4-31
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant alpha 2 (A2m marker)
immunoglobulin heavy constant gamma 1 (G1m marker)
chr19_-_6670078 3.048 TNFSF14
tumor necrosis factor (ligand) superfamily, member 14
chr14_-_91710851 3.047 NM_001177676
GPR68
G protein-coupled receptor 68
chr1_+_17634689 3.044 NM_012387
PADI4
peptidyl arginine deiminase, type IV
chr19_-_44174497 3.029 NM_001005376
NM_001005377
NM_002659
PLAUR


plasminogen activator, urokinase receptor


chr1_+_171060017 3.027 NM_001002294
NM_006894
FMO3

flavin containing monooxygenase 3

chr7_-_1498961 3.018 MICALL2
MICAL-like 2
chr7_+_48128225 2.999 NM_181597
UPP1
uridine phosphorylase 1
chr3_+_151591428 2.988 NM_033050
SUCNR1
succinate receptor 1
chr17_-_56409868 2.984


chr17_-_54893249 2.964 NM_001085430
C17orf67
chromosome 17 open reading frame 67
chr4_+_6695565 2.956 NM_005980
S100P
S100 calcium binding protein P
chr1_-_152009406 2.931 S100A11
S100 calcium binding protein A11
chr1_+_26606621 2.931 SH3BGRL3
SH3 domain binding glutamic acid-rich protein like 3
chr1_-_152009440 2.920 S100A11
S100 calcium binding protein A11
chr17_-_80275370 2.886 NM_006137
CD7
CD7 molecule
chr19_-_19738973 2.885 NM_004720
LPAR2
lysophosphatidic acid receptor 2
chr7_+_94023872 2.854 NM_000089
COL1A2
collagen, type I, alpha 2
chr16_+_50300461 2.840 ADCY7
adenylate cyclase 7
chr1_-_153538305 2.836 NM_005978
S100A2
S100 calcium binding protein A2
chr12_-_53343607 2.834 KRT8
keratin 8
chr1_-_152009467 2.815 S100A11
S100 calcium binding protein A11
chr1_+_27668499 2.798 SYTL1
synaptotagmin-like 1
chr7_+_30791744 2.788 NM_001199219
NM_006774
INMT-FAM188B
INMT

INMT-FAM188B readthrough (non-protein coding)
indolethylamine N-methyltransferase

chr19_-_6591012 2.764 CD70
CD70 molecule
chr8_+_105352050 2.764 NM_030788
TM7SF4
transmembrane 7 superfamily member 4
chr11_-_6676851 2.745 NM_003737
DCHS1
dachsous 1 (Drosophila)
chr22_+_45072936 2.739 PRR5
proline rich 5 (renal)
chr17_-_43502992 2.728 NM_199282
ARHGAP27
Rho GTPase activating protein 27
chr13_-_60325073 2.686


chr12_-_58159386 2.673 CYP27B1
cytochrome P450, family 27, subfamily B, polypeptide 1
chr12_-_10324675 2.669 NM_001172632
NM_001172633
NM_002543
OLR1


oxidized low density lipoprotein (lectin-like) receptor 1


chr6_+_106546736 2.661 NM_182907
PRDM1
PR domain containing 1, with ZNF domain
chr11_-_102401430 2.634 NM_002423
MMP7
matrix metallopeptidase 7 (matrilysin, uterine)
chr6_-_31704318 2.629 NM_001288
CLIC1
chloride intracellular channel 1
chr3_+_46395574 2.627 CCR2
chemokine (C-C motif) receptor 2
chr9_-_35618300 2.623 NM_001782
CD72
CD72 molecule
chr5_-_75919051 2.621 NM_004101
F2RL2
coagulation factor II (thrombin) receptor-like 2
chr6_-_30128688 2.618 NM_006778
NM_052828
TRIM10

tripartite motif containing 10

chr2_+_68961912 2.606 NM_001007231
NM_001166277
ARHGAP25

Rho GTPase activating protein 25

chr6_-_31704070 2.579 CLIC1
chloride intracellular channel 1
chr13_+_78109808 2.571 NM_001160706
NM_003843
NM_144777
SCEL


sciellin


chr2_+_219125737 2.567 NM_001077191
NM_001077194
NM_170699
GPBAR1


G protein-coupled bile acid receptor 1


chr1_-_209824641 2.563 NM_001017402
LAMB3
laminin, beta 3
chr9_-_117111278 2.561 AKNA
AT-hook transcription factor
chr22_+_22550112 2.554


chr5_-_138718941 2.550 SLC23A1
solute carrier family 23 (nucleobase transporters), member 1
chr6_-_31704304 2.549 CLIC1
chloride intracellular channel 1
chr12_-_8219001 2.535 C3AR1
complement component 3a receptor 1
chr7_-_93519990 2.523 NM_006528
TFPI2
tissue factor pathway inhibitor 2
chr2_+_202122753 2.516 NM_001080125
CASP8
caspase 8, apoptosis-related cysteine peptidase
chr6_-_31704093 2.512 CLIC1
chloride intracellular channel 1
chr17_+_48712115 2.511 NM_001144070
NM_003786
ABCC3

ATP-binding cassette, sub-family C (CFTR/MRP), member 3

chr9_-_130341265 2.498 NM_001035534
FAM129B
family with sequence similarity 129, member B
chr16_-_1280162 2.494 NM_024164
TPSB2
TPSAB1
tryptase beta 2 (gene/pseudogene)
tryptase alpha/beta 1
chr1_+_27719151 2.491 NM_005281
GPR3
G protein-coupled receptor 3
chr11_+_706103 2.488 NM_022772
EPS8L2
EPS8-like 2
chr22_+_37309618 2.472 NM_000395
CSF2RB
colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
chr2_-_64371444 2.471 NM_020651
PELI1
pellino homolog 1 (Drosophila)
chr20_+_33759773 2.457 NM_006404
PROCR
protein C receptor, endothelial
chr12_-_8218930 2.429 NM_004054
C3AR1
complement component 3a receptor 1
chr10_-_88730928 2.423 LOC100133190
uncharacterized LOC100133190
chr12_+_56732658 2.409 NM_016584
IL23A
interleukin 23, alpha subunit p19
chr7_+_23286390 2.372 GPNMB
glycoprotein (transmembrane) nmb
chr6_-_31704281 2.365 CLIC1
chloride intracellular channel 1
chr10_+_30723050 2.361 MAP3K8
mitogen-activated protein kinase kinase kinase 8
chr1_+_26606586 2.348 SH3BGRL3
SH3 domain binding glutamic acid-rich protein like 3
chr7_+_26331493 2.332 NM_001199835
NM_013322
SNX10

sorting nexin 10

chr7_+_23286386 2.312 GPNMB
glycoprotein (transmembrane) nmb
chr22_-_30642683 2.293 NM_002309
LIF
leukemia inhibitory factor (cholinergic differentiation factor)
chrX_-_129244471 2.280 NM_001421
ELF4
E74-like factor 4 (ets domain transcription factor)
chrX_-_129244422 2.247 ELF4
E74-like factor 4 (ets domain transcription factor)
chr6_-_31704287 2.242 CLIC1
chloride intracellular channel 1
chr7_-_75443026 2.232 NM_002991
CCL24
chemokine (C-C motif) ligand 24
chr2_+_87754991 2.221 LINC00152
long intergenic non-protein coding RNA 152
chrX_+_123480131 2.202 NM_001114937
NM_002351
SH2D1A

SH2 domain containing 1A

chr19_+_36203829 2.199 NM_014383
ZBTB32
zinc finger and BTB domain containing 32
chr1_-_28520379 2.198 NM_001164721
NM_001164722
PTAFR

platelet-activating factor receptor

chr16_+_67686813 2.175 RLTPR
RGD motif, leucine rich repeats, tropomodulin domain and proline-rich containing
chr7_+_23286384 2.165 GPNMB
glycoprotein (transmembrane) nmb
chr6_-_31704272 2.164 CLIC1
chloride intracellular channel 1
chr1_-_159046555 2.156 NM_004833
AIM2
absent in melanoma 2
chr10_-_6019454 2.154 NM_002189
NM_172200
IL15RA

interleukin 15 receptor, alpha

chr3_+_36421944 2.138 NM_003149
STAC
SH3 and cysteine rich domain
chr20_-_52199635 2.120 NM_006526
ZNF217
zinc finger protein 217
chr7_+_150434679 2.118 GIMAP5
GTPase, IMAP family member 5
chr11_-_102668892 2.115 NM_001145938
NM_002421
MMP1

matrix metallopeptidase 1 (interstitial collagenase)

chr9_-_123688352 2.114 TRAF1
TNF receptor-associated factor 1
chr6_+_50786438 2.113 NM_003221
TFAP2B
transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
chrX_+_12993224 2.112 NM_021109
TMSB4X
thymosin beta 4, X-linked
chr12_+_103981050 2.094 NM_017564
STAB2
stabilin 2

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
4.11 3.55e-28 GO:0002376 immune system process
4.58 2.38e-20 GO:0006955 immune response
3.71 3.76e-11 GO:0002682 regulation of immune system process
3.38 1.60e-10 GO:0006952 defense response
4.33 8.98e-10 GO:0002684 positive regulation of immune system process
5.78 1.76e-08 GO:0051249 regulation of lymphocyte activation
4.04 2.85e-08 GO:0050776 regulation of immune response
3.77 8.46e-08 GO:0001775 cell activation
1.53 9.23e-08 GO:0050896 response to stimulus
5.24 1.27e-07 GO:0002694 regulation of leukocyte activation
2.88 2.29e-07 GO:0009611 response to wounding
5.05 2.76e-07 GO:0050865 regulation of cell activation
4.60 7.30e-07 GO:0050778 positive regulation of immune response
4.97 9.08e-07 GO:0045321 leukocyte activation
5.71 3.73e-06 GO:0051251 positive regulation of lymphocyte activation
1.91 7.24e-06 GO:0006950 response to stress
2.78 1.05e-05 GO:0048584 positive regulation of response to stimulus
5.32 1.15e-05 GO:0002696 positive regulation of leukocyte activation
4.30 1.37e-05 GO:0006954 inflammatory response
5.23 1.51e-05 GO:0050867 positive regulation of cell activation
3.21 1.57e-05 GO:0006928 cellular component movement
2.04 1.96e-05 GO:0048583 regulation of response to stimulus
5.06 2.53e-05 GO:0046649 lymphocyte activation
5.32 2.94e-05 GO:0050863 regulation of T cell activation
3.57 3.06e-05 GO:0051707 response to other organism
1.69 3.86e-05 GO:0007165 signal transduction
4.35 5.33e-05 GO:0009617 response to bacterium
2.61 5.69e-05 GO:0040011 locomotion
2.03 5.73e-05 GO:0007166 cell surface receptor linked signaling pathway
2.74 6.25e-05 GO:0007155 cell adhesion
2.74 6.25e-05 GO:0022610 biological adhesion
5.49 1.32e-04 GO:0002237 response to molecule of bacterial origin
2.51 1.70e-04 GO:0051704 multi-organism process
3.86 1.91e-04 GO:0034097 response to cytokine stimulus
5.27 2.28e-04 GO:0050900 leukocyte migration
5.64 2.51e-04 GO:0032496 response to lipopolysaccharide
5.43 4.03e-04 GO:0050870 positive regulation of T cell activation
3.05 4.12e-04 GO:0009607 response to biotic stimulus
3.28 4.94e-04 GO:0016477 cell migration
3.11 7.76e-04 GO:0048870 cell motility
3.11 7.76e-04 GO:0051674 localization of cell
1.54 8.23e-04 GO:0051716 cellular response to stimulus
6.00 9.68e-04 GO:0070663 regulation of leukocyte proliferation
4.15 1.09e-03 GO:0002253 activation of immune response
1.79 1.14e-03 GO:0042221 response to chemical stimulus
1.57 1.32e-03 GO:0023052 signaling
1.69 1.63e-03 GO:0048518 positive regulation of biological process
2.10 1.96e-03 GO:0010033 response to organic substance
5.47 2.60e-03 GO:0042110 T cell activation
4.08 2.88e-03 GO:0071345 cellular response to cytokine stimulus
3.18 4.36e-03 GO:0045087 innate immune response
5.72 4.51e-03 GO:0050670 regulation of lymphocyte proliferation
5.66 4.97e-03 GO:0002429 immune response-activating cell surface receptor signaling pathway
5.66 4.97e-03 GO:0032944 regulation of mononuclear cell proliferation
3.65 6.23e-03 GO:0030334 regulation of cell migration
2.22 6.38e-03 GO:0042127 regulation of cell proliferation
1.75 6.54e-03 GO:0065008 regulation of biological quality
5.45 7.28e-03 GO:0002768 immune response-regulating cell surface receptor signaling pathway
3.61 7.34e-03 GO:2000145 regulation of cell motility
2.62 1.08e-02 GO:0050878 regulation of body fluid levels
3.45 1.31e-02 GO:0001817 regulation of cytokine production
6.41 1.37e-02 GO:0050671 positive regulation of lymphocyte proliferation
6.32 1.53e-02 GO:0032946 positive regulation of mononuclear cell proliferation
6.24 1.71e-02 GO:0070665 positive regulation of leukocyte proliferation
3.96 1.75e-02 GO:0019221 cytokine-mediated signaling pathway
2.67 1.75e-02 GO:0006935 chemotaxis
2.67 1.75e-02 GO:0042330 taxis
2.53 2.03e-02 GO:0042060 wound healing
3.30 2.38e-02 GO:0040012 regulation of locomotion
3.29 2.49e-02 GO:0051270 regulation of cellular component movement
1.28 2.51e-02 GO:0065007 biological regulation
4.39 2.53e-02 GO:0002252 immune effector process
2.66 2.79e-02 GO:0007596 blood coagulation
2.66 2.79e-02 GO:0050817 coagulation
5.85 2.90e-02 GO:0006959 humoral immune response
2.65 3.09e-02 GO:0007599 hemostasis
4.30 3.12e-02 GO:0030335 positive regulation of cell migration
4.30 3.12e-02 GO:2000147 positive regulation of cell motility
7.91 3.28e-02 GO:0032680 regulation of tumor necrosis factor production
38.97 3.50e-02 GO:0071731 response to nitric oxide
3.95 3.57e-02 GO:0002757 immune response-activating signal transduction
5.57 4.31e-02 GO:0050730 regulation of peptidyl-tyrosine phosphorylation
4.16 4.38e-02 GO:0040017 positive regulation of locomotion
3.86 4.54e-02 GO:0002764 immune response-regulating signaling pathway

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
2.40 4.45e-13 GO:0005576 extracellular region
2.90 2.71e-10 GO:0044421 extracellular region part
2.93 8.15e-08 GO:0005615 extracellular space
1.64 5.17e-07 GO:0005886 plasma membrane
1.61 1.28e-06 GO:0071944 cell periphery
1.89 8.30e-06 GO:0044459 plasma membrane part
2.25 8.50e-06 GO:0031226 intrinsic to plasma membrane
2.25 1.21e-05 GO:0005887 integral to plasma membrane
3.46 2.87e-05 GO:0031012 extracellular matrix
3.40 4.13e-04 GO:0005578 proteinaceous extracellular matrix

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
12.99 9.69e-07 GO:0003823 antigen binding
3.56 1.44e-05 GO:0030246 carbohydrate binding
4.62 1.32e-04 GO:0005126 cytokine receptor binding
9.17 1.52e-04 GO:0042379 chemokine receptor binding
4.38 2.74e-04 GO:0005529 sugar binding
5.78 3.55e-04 GO:0019955 cytokine binding
1.91 3.66e-04 GO:0004872 receptor activity
9.04 7.43e-04 GO:0008009 chemokine activity
4.02 1.73e-03 GO:0005125 cytokine activity
2.07 5.64e-03 GO:0005102 receptor binding
14.85 3.56e-02 GO:0030228 lipoprotein particle receptor activity
13.86 4.78e-02 GO:0005161 platelet-derived growth factor receptor binding
13.86 4.78e-02 GO:0008329 pattern recognition receptor activity