Motif ID: FOX{D1,D2}.p2

Z-value: 2.043


Transcription factors associated with FOX{D1,D2}.p2:

Gene SymbolEntrez IDGene Name
FOXD1 2297 forkhead box D1
FOXD2 2306 forkhead box D2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
FOXD2hg19_v1_chr1_+_47901688_479016880.222.3e-01Click!
FOXD1hg19_v1_chr5_-_72743829_72743890-0.202.8e-01Click!


Activity profile for motif FOX{D1,D2}.p2.

activity profile for motif FOX{D1,D2}.p2


Sorted Z-values histogram for motif FOX{D1,D2}.p2

Sorted Z-values for motif FOX{D1,D2}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of FOX{D1,D2}.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_+_134832765 5.780 NM_018295
 TMEM140
transmembrane protein 140
chr7_-_95225802 4.810 NM_002612
 PDK4
pyruvate dehydrogenase kinase, isozyme 4
chr1_-_26393984 4.781 NM_032588
 TRIM63
tripartite motif containing 63
chr1_+_145438437 4.641 NM_006472
 TXNIP
thioredoxin interacting protein
chr4_-_186456580 4.105 NM_001114107
NM_014476
 PDLIM3

PDZ and LIM domain 3

chrX_-_55208943 4.004 NM_001190708
 MTRNR2L10
MT-RNR2-like 10
chr19_+_859673 3.925 CFD
complement factor D (adipsin)
chr19_+_859658 3.853 NM_001928
 CFD
complement factor D (adipsin)
chr22_+_26138110 3.672 NM_032608
 MYO18B
myosin XVIIIB
chr10_+_63808968 3.671 NM_001244638
 ARID5B
AT rich interactive domain 5B (MRF1-like)
chr4_+_119947816 3.665 SYNPO2
synaptopodin 2
chr2_-_192711923 3.663 NM_004657
 SDPR
serum deprivation response
chr19_+_18496966 3.437 NM_004864
 GDF15
growth differentiation factor 15
chr21_+_30517897 3.343 C21orf7
chromosome 21 open reading frame 7
chrX_-_15333726 3.319 NM_001201583
NM_080873
 ASB11

ankyrin repeat and SOCS box containing 11

chr12_-_53074172 3.257 NM_006121
 KRT1
keratin 1
chr1_-_207095198 3.200 NM_001193338
NM_001142473
NM_005449
 FAIM3


Fas apoptotic inhibitory molecule 3


chr2_-_192711651 3.186 SDPR
serum deprivation response
chr1_-_161147757 3.178 NM_001199873
NM_001199874
NM_003779
 B4GALT3


UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 3


chr22_+_26138168 3.163 MYO18B
myosin XVIIIB

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 13 of 13 entries
Enrichment   P-value GO Accession GO Term
2.00 1.06e-03 GO:2000112 regulation of cellular macromolecule biosynthetic process
2.00 4.84e-03 GO:0006355 regulation of transcription, DNA-dependent
1.99 9.50e-04 GO:0010556 regulation of macromolecule biosynthetic process
1.96 5.54e-03 GO:0051252 regulation of RNA metabolic process
1.92 1.51e-03 GO:0031326 regulation of cellular biosynthetic process
1.90 2.11e-03 GO:0009889 regulation of biosynthetic process
1.86 1.18e-02 GO:0010468 regulation of gene expression
1.78 3.70e-02 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.71 1.39e-02 GO:0060255 regulation of macromolecule metabolic process
1.68 1.23e-02 GO:0031323 regulation of cellular metabolic process
1.65 3.33e-02 GO:0080090 regulation of primary metabolic process
1.37 3.87e-02 GO:0050789 regulation of biological process
1.35 2.42e-02 GO:0065007 biological regulation

Gene overrepresentation in compartment category:

Showing 1 to 1 of 1 entries
Enrichment   P-value GO Accession GO Term
1.54 1.52e-04 GO:0005634 nucleus

Gene overrepresentation in function category:

Showing 1 to 6 of 6 entries
Enrichment   P-value GO Accession GO Term
4.58 2.39e-03 GO:0019900 kinase binding
4.02 1.99e-03 GO:0016563 transcription activator activity
2.76 7.52e-03 GO:0043565 sequence-specific DNA binding
2.57 1.09e-03 GO:0001071 nucleic acid binding transcription factor activity
2.57 1.09e-03 GO:0003700 sequence-specific DNA binding transcription factor activity
2.51 1.70e-03 GO:0030528 transcription regulator activity