Motif ID: FOX{I1,J2}.p2

Z-value: 1.557


Transcription factors associated with FOX{I1,J2}.p2:

Gene SymbolEntrez IDGene Name
FOXI1 2299 forkhead box I1
FOXJ2 55810 forkhead box J2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
FOXJ2hg19_v1_chr12_+_8185241_81857390.441.1e-02Click!
FOXI1hg19_v1_chr5_+_169532900_169533042-0.086.6e-01Click!


Activity profile for motif FOX{I1,J2}.p2.

activity profile for motif FOX{I1,J2}.p2


Sorted Z-values histogram for motif FOX{I1,J2}.p2

Sorted Z-values for motif FOX{I1,J2}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of FOX{I1,J2}.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr13_+_23755059 15.475 NM_000231
 SGCG
sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)
chr7_+_151653463 11.754 NM_145292
 GALNTL5
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 5
chr12_+_101988746 8.562 NM_002465
NM_206819
NM_206820
NM_206821
 MYBPC1



myosin binding protein C, slow type



chr5_+_53751430 8.291 NM_006308
 HSPB3
heat shock 27kDa protein 3
chr16_+_6823809 5.915 NM_001142334
 RBFOX1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr16_+_30064470 5.687 ALDOA
aldolase A, fructose-bisphosphate
chr12_+_112890999 5.251 PTPN11
protein tyrosine phosphatase, non-receptor type 11
chr16_+_30064410 4.924 NM_000034
 ALDOA
aldolase A, fructose-bisphosphate
chr14_+_32798478 4.601 NM_004274
 AKAP6
A kinase (PRKA) anchor protein 6
chr19_-_48614013 4.530 NM_001159322
NM_001159323
NM_003706
 PLA2G4C


phospholipase A2, group IVC (cytosolic, calcium-independent)


chr4_-_186456580 4.513 NM_001114107
NM_014476
 PDLIM3

PDZ and LIM domain 3

chr1_+_150480486 4.316 NM_001202858
NM_004425
NM_022664
 ECM1


extracellular matrix protein 1


chr5_+_173472692 4.277 NM_015980
 HMP19
HMP19 protein
chr3_+_158787040 4.231 NM_001197113
NM_001197114
NM_001042705
NM_001042706
NM_001197100
 IQCJ-SCHIP1

IQCJ


IQCJ-SCHIP1 readthrough

IQ motif containing J


chr19_-_45822841 4.088 CKM
creatine kinase, muscle
chr14_+_23845932 4.020 NM_001037288
NM_138460
 CMTM5

CKLF-like MARVEL transmembrane domain containing 5

chr5_+_173472737 3.875 HMP19
HMP19 protein
chr4_-_65275000 3.756 NM_001010874
 TECRL
trans-2,3-enoyl-CoA reductase-like
chr6_-_123957941 3.720 NM_001251987
NM_006073
 TRDN

triadin

chr13_-_36429798 3.674 NM_001195415
NM_001195416
NM_001195430
 DCLK1


doublecortin-like kinase 1



Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 28 entries
Enrichment   P-value GO Accession GO Term
14.13 2.09e-02 GO:0016339 calcium-dependent cell-cell adhesion
12.83 9.04e-04 GO:0030049 muscle filament sliding
12.83 9.04e-04 GO:0033275 actin-myosin filament sliding
12.72 5.85e-03 GO:0007416 synapse assembly
12.56 3.82e-02 GO:0031032 actomyosin structure organization
12.50 1.09e-03 GO:0070252 actin-mediated cell contraction
10.64 6.76e-04 GO:0030048 actin filament-based movement
10.44 7.88e-04 GO:0050808 synapse organization
8.16 1.87e-09 GO:0006936 muscle contraction
7.50 8.58e-09 GO:0003012 muscle system process
6.22 4.99e-04 GO:0007156 homophilic cell adhesion
5.18 8.76e-03 GO:0043062 extracellular structure organization
4.80 3.22e-03 GO:0007517 muscle organ development
3.67 2.91e-02 GO:0061061 muscle structure development
3.65 1.61e-02 GO:0016337 cell-cell adhesion
3.57 4.63e-04 GO:0007268 synaptic transmission
3.52 4.58e-02 GO:0030029 actin filament-based process
3.18 2.94e-03 GO:0019226 transmission of nerve impulse
3.18 2.94e-03 GO:0035637 multicellular organismal signaling
2.78 9.57e-04 GO:0007155 cell adhesion

Gene overrepresentation in compartment category:

Showing 1 to 17 of 17 entries
Enrichment   P-value GO Accession GO Term
9.94 2.23e-10 GO:0030016 myofibril
9.69 3.27e-08 GO:0030017 sarcomere
9.38 5.94e-10 GO:0043292 contractile fiber
9.17 3.79e-02 GO:0016529 sarcoplasmic reticulum
9.01 2.10e-08 GO:0044449 contractile fiber part
8.93 4.31e-02 GO:0016528 sarcoplasm
8.93 4.31e-02 GO:0030018 Z disc
8.48 1.35e-02 GO:0031674 I band
8.14 1.70e-02 GO:0044309 neuron spine
7.42 8.06e-03 GO:0016459 myosin complex
3.33 9.77e-04 GO:0045202 synapse
3.33 9.72e-03 GO:0005578 proteinaceous extracellular matrix
3.32 1.76e-02 GO:0015629 actin cytoskeleton
3.01 1.07e-02 GO:0043005 neuron projection
1.70 1.81e-02 GO:0044459 plasma membrane part
1.55 7.35e-04 GO:0005886 plasma membrane
1.53 1.35e-03 GO:0071944 cell periphery

Gene overrepresentation in function category:

Showing 1 to 6 of 6 entries
Enrichment   P-value GO Accession GO Term
29.07 2.37e-02 GO:0051393 alpha-actinin binding
25.44 3.75e-02 GO:0042805 actinin binding
12.62 4.12e-05 GO:0008307 structural constituent of muscle
3.89 2.23e-04 GO:0003779 actin binding
3.35 8.17e-07 GO:0005509 calcium ion binding
3.16 1.52e-04 GO:0008092 cytoskeletal protein binding