Motif ID: FOXD3.p2

Z-value: 1.281


Transcription factors associated with FOXD3.p2:

Gene SymbolEntrez IDGene Name
FOXD3 27022 forkhead box D3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
FOXD3hg19_v1_chr1_+_63788729_63788729-0.345.6e-02Click!


Activity profile for motif FOXD3.p2.

activity profile for motif FOXD3.p2


Sorted Z-values histogram for motif FOXD3.p2

Sorted Z-values for motif FOXD3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of FOXD3.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr22_+_23054862 8.619 IGLV3-21
IGLJ3
IGLC1
immunoglobulin lambda variable 3-21
immunoglobulin lambda joining 3
immunoglobulin lambda constant 1 (Mcg marker)
chr15_+_58430394 4.762 NM_020980
 AQP9
aquaporin 9
chr1_-_160681552 3.980 NM_001778
 CD48
CD48 molecule
chr19_+_6464259 3.979 NM_139161
NM_174881
 CRB3

crumbs homolog 3 (Drosophila)

chr2_-_219031646 3.802 NM_000634
 CXCR1
chemokine (C-X-C motif) receptor 1
chr12_+_54892567 3.729 NM_001184976
 NCKAP1L
NCK-associated protein 1-like
chr19_-_14785626 3.644 NM_032571
 EMR3
egf-like module containing, mucin-like, hormone receptor-like 3
chr12_+_9980076 3.265 NM_016523
 KLRF1
killer cell lectin-like receptor subfamily F, member 1
chr11_+_62186506 3.070 NM_003357
 SCGB1A1
secretoglobin, family 1A, member 1 (uteroglobin)
chr21_+_39628869 3.032 NM_170736
 KCNJ15
potassium inwardly-rectifying channel, subfamily J, member 15
chr2_-_32490688 2.919 NM_001199139
NM_021209
 NLRC4

NLR family, CARD domain containing 4

chr19_-_11689765 2.822 NM_001111035
NM_001111036
 ACP5

acid phosphatase 5, tartrate resistant

chr19_-_50847957 2.744 NAPSB
napsin B aspartic peptidase pseudogene
chr19_-_52255099 2.739 NM_001193306
NM_002029
 FPR1

formyl peptide receptor 1

chr1_-_160492982 2.730 NM_001184714
NM_001184715
NM_001184716
NM_052931
 SLAMF6



SLAM family member 6



chr4_-_71532206 2.720 IGJ
immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
chr19_-_39826676 2.708 NM_004877
 GMFG
glia maturation factor, gamma
chr3_-_183273407 2.664 NM_130446
 KLHL6
kelch-like 6 (Drosophila)
chr6_+_150690027 2.642 NM_001164694
NM_001164695
NM_203395
 IYD


iodotyrosine deiodinase


chr4_-_71532341 2.620 NM_144646
 IGJ
immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 75 entries
Enrichment   P-value GO Accession GO Term
54.83 1.19e-02 GO:0045586 regulation of gamma-delta T cell differentiation
54.83 1.19e-02 GO:0045588 positive regulation of gamma-delta T cell differentiation
47.00 2.08e-02 GO:0046643 regulation of gamma-delta T cell activation
47.00 2.08e-02 GO:0046645 positive regulation of gamma-delta T cell activation
41.13 3.30e-02 GO:0002834 regulation of response to tumor cell
41.13 3.30e-02 GO:0002836 positive regulation of response to tumor cell
41.13 3.30e-02 GO:0002837 regulation of immune response to tumor cell
41.13 3.30e-02 GO:0002839 positive regulation of immune response to tumor cell
36.56 4.91e-02 GO:0002833 positive regulation of response to biotic stimulus
29.25 6.88e-03 GO:0002717 positive regulation of natural killer cell mediated immunity
29.25 6.88e-03 GO:0045954 positive regulation of natural killer cell mediated cytotoxicity
29.25 6.88e-03 GO:0050854 regulation of antigen receptor-mediated signaling pathway
28.86 5.08e-04 GO:0050853 B cell receptor signaling pathway
24.37 1.51e-02 GO:0002715 regulation of natural killer cell mediated immunity
24.37 1.51e-02 GO:0042269 regulation of natural killer cell mediated cytotoxicity
21.94 2.36e-02 GO:0009595 detection of biotic stimulus
19.94 3.51e-02 GO:0046638 positive regulation of alpha-beta T cell differentiation
19.59 4.02e-03 GO:0001910 regulation of leukocyte mediated cytotoxicity
19.08 4.22e-02 GO:0001912 positive regulation of leukocyte mediated cytotoxicity
17.69 6.79e-03 GO:0031341 regulation of cell killing

Gene overrepresentation in compartment category:

Showing 1 to 10 of 10 entries
Enrichment   P-value GO Accession GO Term
3.61 1.77e-02 GO:0009986 cell surface
2.85 2.21e-05 GO:0005887 integral to plasma membrane
2.79 3.32e-05 GO:0031226 intrinsic to plasma membrane
2.27 2.95e-05 GO:0044459 plasma membrane part
1.92 7.70e-07 GO:0071944 cell periphery
1.89 2.96e-06 GO:0005886 plasma membrane
1.63 1.85e-04 GO:0016021 integral to membrane
1.62 1.86e-04 GO:0031224 intrinsic to membrane
1.54 2.27e-04 GO:0044425 membrane part
1.40 3.71e-03 GO:0016020 membrane

Gene overrepresentation in function category:

Showing 1 to 11 of 11 entries
Enrichment   P-value GO Accession GO Term
32.90 1.45e-02 GO:0032393 MHC class I receptor activity
19.08 8.76e-03 GO:0001608 nucleotide receptor activity, G-protein coupled
19.08 8.76e-03 GO:0045028 purinergic nucleotide receptor activity, G-protein coupled
16.45 2.64e-04 GO:0003823 antigen binding
14.63 2.58e-02 GO:0001614 purinergic nucleotide receptor activity
14.63 2.58e-02 GO:0016502 nucleotide receptor activity
12.91 4.24e-02 GO:0035586 purinergic receptor activity
2.41 4.24e-03 GO:0004888 transmembrane receptor activity
2.30 7.72e-04 GO:0004872 receptor activity
2.22 1.94e-04 GO:0004871 signal transducer activity
2.22 1.94e-04 GO:0060089 molecular transducer activity