Motif ID: FOXD3.p2

Z-value: 1.281


Transcription factors associated with FOXD3.p2:

Gene SymbolEntrez IDGene Name
FOXD3 27022 forkhead box D3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
FOXD3hg19_v1_chr1_+_63788729_63788729-0.345.6e-02Click!


Activity profile for motif FOXD3.p2.

activity profile for motif FOXD3.p2


Sorted Z-values histogram for motif FOXD3.p2

Sorted Z-values for motif FOXD3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of FOXD3.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr22_+_23054862 8.619 IGLV3-21
IGLJ3
IGLC1
immunoglobulin lambda variable 3-21
immunoglobulin lambda joining 3
immunoglobulin lambda constant 1 (Mcg marker)
chr15_+_58430394 4.762 NM_020980
AQP9
aquaporin 9
chr1_-_160681552 3.980 NM_001778
CD48
CD48 molecule
chr19_+_6464259 3.979 NM_139161
NM_174881
CRB3

crumbs homolog 3 (Drosophila)

chr2_-_219031646 3.802 NM_000634
CXCR1
chemokine (C-X-C motif) receptor 1
chr12_+_54892567 3.729 NM_001184976
NCKAP1L
NCK-associated protein 1-like
chr19_-_14785626 3.644 NM_032571
EMR3
egf-like module containing, mucin-like, hormone receptor-like 3
chr12_+_9980076 3.265 NM_016523
KLRF1
killer cell lectin-like receptor subfamily F, member 1
chr11_+_62186506 3.070 NM_003357
SCGB1A1
secretoglobin, family 1A, member 1 (uteroglobin)
chr21_+_39628869 3.032 NM_170736
KCNJ15
potassium inwardly-rectifying channel, subfamily J, member 15
chr2_-_32490688 2.919 NM_001199139
NM_021209
NLRC4

NLR family, CARD domain containing 4

chr19_-_11689765 2.822 NM_001111035
NM_001111036
ACP5

acid phosphatase 5, tartrate resistant

chr19_-_50847957 2.744 NAPSB
napsin B aspartic peptidase pseudogene
chr19_-_52255099 2.739 NM_001193306
NM_002029
FPR1

formyl peptide receptor 1

chr1_-_160492982 2.730 NM_001184714
NM_001184715
NM_001184716
NM_052931
SLAMF6



SLAM family member 6



chr4_-_71532206 2.720 IGJ
immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
chr19_-_39826676 2.708 NM_004877
GMFG
glia maturation factor, gamma
chr3_-_183273407 2.664 NM_130446
KLHL6
kelch-like 6 (Drosophila)
chr6_+_150690027 2.642 NM_001164694
NM_001164695
NM_203395
IYD


iodotyrosine deiodinase


chr4_-_71532341 2.620 NM_144646
IGJ
immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
chr12_-_96390002 2.483 NM_002108
HAL
histidine ammonia-lyase
chr22_+_37678565 2.444 CYTH4
cytohesin 4
chrX_+_135730335 2.403 NM_000074
CD40LG
CD40 ligand
chr4_+_155484131 2.340 NM_001184741
NM_005141
FGB

fibrinogen beta chain

chr4_+_40198526 2.335 NM_004310
RHOH
ras homolog gene family, member H
chr1_-_27952591 2.327 NM_001042747
FGR
Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog
chr9_-_139927291 2.297 NM_004479
FUT7
fucosyltransferase 7 (alpha (1,3) fucosyltransferase)
chr21_-_27512668 2.272 NM_001136016
APP
amyloid beta (A4) precursor protein
chr1_+_84630575 2.251 NM_001242860
NM_001242861
PRKACB

protein kinase, cAMP-dependent, catalytic, beta

chr6_+_131894343 2.229 NM_000045
NM_001244438
ARG1

arginase, liver

chr9_+_79115548 2.200 NM_001097636
GCNT1
glucosaminyl (N-acetyl) transferase 1, core 2
chr1_+_241695433 2.192 NM_003679
KMO
kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
chr19_+_1026271 2.163 NM_004368
NM_201277
CNN2

calponin 2

chr3_+_132036210 2.147 NM_001099
NM_001134194
ACPP

acid phosphatase, prostate

chr3_+_121774208 2.106 NM_001206924
NM_001206925
NM_175862
CD86


CD86 molecule


chr4_-_155511838 2.100 NM_000508
NM_021871
FGA

fibrinogen alpha chain

chr9_-_117568292 2.096 NM_005118
TNFSF15
tumor necrosis factor (ligand) superfamily, member 15
chr4_-_39033981 2.091 NM_024943
TMEM156
transmembrane protein 156
chr1_-_100231348 2.089 NM_001013660
FRRS1
ferric-chelate reductase 1
chr5_+_40841296 2.071 NM_032587
CARD6
caspase recruitment domain family, member 6
chr11_+_63304272 2.068 NM_004585
RARRES3
retinoic acid receptor responder (tazarotene induced) 3
chr11_-_57158103 2.049 NM_001243245
NM_002728
PRG2

proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein)

chr18_-_67615088 2.027 CD226
CD226 molecule
chr22_+_37678519 2.018 CYTH4
cytohesin 4
chr15_-_55562483 2.006 NM_183234
NM_004580
RAB27A

RAB27A, member RAS oncogene family

chr22_+_37678423 1.974 NM_013385
CYTH4
cytohesin 4
chr3_+_121902529 1.954 NM_000388
CASR
calcium-sensing receptor
chr12_+_8666135 1.913 NM_080387
CLEC4D
C-type lectin domain family 4, member D
chr19_-_50868877 1.885 NM_004851
NAPSA
napsin A aspartic peptidase
chr2_-_128100673 1.861 NM_006609
MAP3K2
mitogen-activated protein kinase kinase kinase 2
chr6_-_159466019 1.860 NM_054114
NM_138810
NM_152133
TAGAP


T-cell activation RhoGTPase activating protein


chr1_-_89664510 1.859 NM_052941
GBP4
guanylate binding protein 4
chr7_-_87342569 1.844 NM_000927
ABCB1
ATP-binding cassette, sub-family B (MDR/TAP), member 1
chr1_+_32739711 1.830 NM_001042771
LCK
lymphocyte-specific protein tyrosine kinase
chr9_+_127420690 1.820 MIR181A2HG
MIR181A2 host gene (non-protein coding)
chr14_-_23288912 1.819 NM_001126106
SLC7A7
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr19_+_52266640 1.809 NM_001462
FPR2
formyl peptide receptor 2
chr5_+_92918924 1.800 NM_005654
NR2F1
nuclear receptor subfamily 2, group F, member 1
chr4_-_84035888 1.763 PLAC8
placenta-specific 8
chr18_-_47814691 1.748 NM_001101654
NM_014593
CXXC1

CXXC finger protein 1

chr12_+_54891539 1.731 NCKAP1L
NCK-associated protein 1-like
chr6_+_26365397 1.707 NM_001197247
NM_001197249
NM_007047
NM_001197248
BTN3A2



butyrophilin, subfamily 3, member A2



chr6_+_29855349 1.662 HLA-H
major histocompatibility complex, class I, H (pseudogene)
chr3_+_151591428 1.628 NM_033050
SUCNR1
succinate receptor 1
chr4_-_83347222 1.621 HNRPDL
heterogeneous nuclear ribonucleoprotein D-like
chr12_+_13043955 1.621 NM_003979
GPRC5A
G protein-coupled receptor, family C, group 5, member A
chr20_+_19870209 1.610 NM_018993
RIN2
Ras and Rab interactor 2
chr4_-_84035908 1.584 NM_001130715
NM_016619
PLAC8

placenta-specific 8

chr2_+_135596185 1.579 NM_138326
ACMSD
aminocarboxymuconate semialdehyde decarboxylase
chr3_-_15382874 1.573 NM_001018009
SH3BP5
SH3-domain binding protein 5 (BTK-associated)
chr2_-_158300517 1.565 NM_004288
CYTIP
cytohesin 1 interacting protein
chr12_-_105322056 1.554 NM_032148
SLC41A2
solute carrier family 41, member 2
chr2_-_89292396 1.549 IGKC
immunoglobulin kappa constant
chr15_-_54051837 1.546 NM_182758
WDR72
WD repeat domain 72
chr14_-_106714594 1.515


chrX_+_123234462 1.512 STAG2
stromal antigen 2
chr19_-_16250695 1.512


chr1_+_198608244 1.509 PTPRC
protein tyrosine phosphatase, receptor type, C
chr4_+_71062241 1.501 NM_017855
ODAM
odontogenic, ameloblast asssociated
chr19_+_55128601 1.498 NM_006669
LILRB1
leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1
chr1_-_153085963 1.498 NM_001014450
SPRR2A
SPRR2F
small proline-rich protein 2A
small proline-rich protein 2F
chr19_+_36486042 1.478 NM_001042631
SDHAF1
succinate dehydrogenase complex assembly factor 1
chrX_-_101410761 1.478 NM_001159560
NM_001012978
BEX5

brain expressed, X-linked 5

chr3_-_105421044 1.471 CBLB
Cas-Br-M (murine) ecotropic retroviral transforming sequence b
chr12_+_54891522 1.456 NCKAP1L
NCK-associated protein 1-like
chr21_+_43823970 1.454 NM_001001895
NM_001243467
NM_018961
UBASH3A


ubiquitin associated and SH3 domain containing A


chr1_+_198608136 1.431 NM_002838
NM_080921
NM_080923
PTPRC


protein tyrosine phosphatase, receptor type, C


chr6_+_150263120 1.425 NM_025217
ULBP2
UL16 binding protein 2
chr6_+_45296053 1.424 NM_001015051
NM_001024630
RUNX2

runt-related transcription factor 2

chr6_-_133035180 1.421 NM_004666
VNN1
vanin 1
chr9_+_93589704 1.417 NM_001174167
SYK
spleen tyrosine kinase
chr15_-_55563091 1.399 NM_183236
RAB27A
RAB27A, member RAS oncogene family
chr6_-_75965845 1.378 TMEM30A
transmembrane protein 30A
chr9_-_117156684 1.373 NM_030767
AKNA
AT-hook transcription factor
chr9_+_127054246 1.362 NM_001166170
NM_001166171
NEK6

NIMA (never in mitosis gene a)-related kinase 6

chr14_-_61748510 1.352 NM_001017970
TMEM30B
transmembrane protein 30B
chr12_-_121735558 1.349 CAMKK2
calcium/calmodulin-dependent protein kinase kinase 2, beta
chr12_+_56915587 1.341 NM_002898
RBMS2
RNA binding motif, single stranded interacting protein 2
chr14_+_88471467 1.337 NM_003608
GPR65
G protein-coupled receptor 65
chr9_-_4299915 1.323 GLIS3
GLIS family zinc finger 3
chr3_+_122044010 1.299 NM_005213
CSTA
cystatin A (stefin A)
chr12_-_10282680 1.297 NM_022570
NM_197947
NM_197948
NM_197949
NM_197950
NM_197954
CLEC7A





C-type lectin domain family 7, member A





chrX_+_1387692 1.297 NM_001161529
NM_001161531
NM_001161532
NM_006140
NM_172245
NM_172246
NM_172249
CSF2RA






colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)






chrX_-_23855456 1.297 RPL9
ribosomal protein L9
chr10_-_32667543 1.280 EPC1
enhancer of polycomb homolog 1 (Drosophila)
chr5_-_39203061 1.277 FYB
FYN binding protein
chr16_-_28620648 1.275 NM_177530
NM_177534
SULT1A1

sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1

chr4_-_103266577 1.272 NM_001135146
SLC39A8
solute carrier family 39 (zinc transporter), member 8
chr15_+_94841429 1.260 NM_001159643
NM_018349
MCTP2

multiple C2 domains, transmembrane 2

chr1_+_248020481 1.257 NM_015431
TRIM58
tripartite motif containing 58
chr20_+_30697291 1.257 NM_014742
TM9SF4
transmembrane 9 superfamily protein member 4
chr21_+_39628663 1.255 NM_002243
KCNJ15
potassium inwardly-rectifying channel, subfamily J, member 15
chr7_-_38313232 1.251 NM_001003799
NM_001003806
TARP

TRGV9
TCR gamma alternate reading frame protein

T cell receptor gamma variable 9
chr12_-_113841654 1.249 NM_006843
SDS
serine dehydratase
chr12_+_47610051 1.233 NM_138371
FAM113B
family with sequence similarity 113, member B
chr5_-_41213513 1.227 NM_000065
C6
complement component 6
chr15_+_100173182 1.222 NM_001130928
MEF2A
myocyte enhancer factor 2A
chr20_-_56195446 1.218 NM_001160417
NM_001160418
NM_001160419
NM_030776
ZBP1



Z-DNA binding protein 1



chr1_-_156265395 1.217 NM_144580
C1orf85
chromosome 1 open reading frame 85
chrX_-_48327739 1.214 SLC38A5
solute carrier family 38, member 5
chr16_+_27341305 1.213 IL4R
interleukin 4 receptor
chr15_+_94899163 1.212 NM_001159644
MCTP2
multiple C2 domains, transmembrane 2
chr3_-_151047309 1.210 NM_176894
P2RY13
purinergic receptor P2Y, G-protein coupled, 13
chr3_+_132036276 1.200 ACPP
acid phosphatase, prostate
chr19_-_4831711 1.199 NM_182919
TICAM1
toll-like receptor adaptor molecule 1
chr13_-_99959649 1.197 NM_004951
GPR183
G protein-coupled receptor 183
chr1_+_209878135 1.194 NM_005525
HSD11B1
hydroxysteroid (11-beta) dehydrogenase 1
chr12_+_49297892 1.190 NM_033124
CCDC65
coiled-coil domain containing 65
chr18_+_61254533 1.187 NM_012397
SERPINB13
serpin peptidase inhibitor, clade B (ovalbumin), member 13
chr3_+_114012832 1.186 NM_173799
TIGIT
T cell immunoreceptor with Ig and ITIM domains
chrX_+_70765479 1.183 OGT
O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase)
chr19_+_14491920 1.181 NM_001025160
NM_001784
NM_078481
CD97


CD97 molecule


chr4_-_38858407 1.174 NM_006068
TLR6
toll-like receptor 6
chr2_+_201473942 1.165 AOX1
aldehyde oxidase 1
chr3_-_120401401 1.160 NM_000187
HGD
homogentisate 1,2-dioxygenase
chr12_-_10542616 1.157 NM_007360
KLRK1
killer cell lectin-like receptor subfamily K, member 1
chr3_+_171561138 1.154 NM_001164436
TMEM212
transmembrane protein 212
chr19_+_52264452 1.153 NM_001005738
FPR2
formyl peptide receptor 2
chr3_-_150920946 1.148 NM_013308
GPR171
G protein-coupled receptor 171
chr3_+_151488214 1.148 LOC201651
arylacetamide deacetylase (esterase) pseudogene
chr1_-_161008710 1.142 TSTD1
thiosulfate sulfurtransferase (rhodanese)-like domain containing 1
chr12_+_105153258 1.140 CHST11
carbohydrate (chondroitin 4) sulfotransferase 11
chr4_+_36285643 1.139 NM_001170700
DTHD1
death domain containing 1
chr3_-_120400957 1.137 HGD
homogentisate 1,2-dioxygenase
chr9_+_135894806 1.133 EEF1A1
eukaryotic translation elongation factor 1 alpha 1
chr17_-_5138049 1.129 NM_207103
SCIMP
SLP adaptor and CSK interacting membrane protein
chr2_-_89619820 1.125 IGKC
immunoglobulin kappa constant
chr12_+_21284127 1.124 NM_006446
SLCO1B1
solute carrier organic anion transporter family, member 1B1
chr10_+_71561643 1.123 NM_001130103
NM_080798
NM_080800
NM_080801
NM_080802
NM_080805
COL13A1





collagen, type XIII, alpha 1





chr19_+_11200037 1.112 NM_000527
NM_001195798
NM_001195799
NM_001195800
NM_001195802
NM_001195803
LDLR





low density lipoprotein receptor





chr2_-_85637486 1.105 NM_001747
CAPG
capping protein (actin filament), gelsolin-like
chr3_+_122296432 1.099 NM_001113523
PARP15
poly (ADP-ribose) polymerase family, member 15
chr16_-_28634873 1.087 NM_177536
SULT1A1
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
chr22_-_25777543 1.085 NM_001135772
LRP5L
low density lipoprotein receptor-related protein 5-like
chr17_+_7942351 1.083 NM_001039130
NM_001039131
NM_001141
ALOX15B


arachidonate 15-lipoxygenase, type B


chr1_+_44064509 1.083 PTPRF
protein tyrosine phosphatase, receptor type, F
chr1_-_161008733 1.082 NM_001113205
NM_001113206
NM_001113207
TSTD1


F11R
thiosulfate sulfurtransferase (rhodanese)-like domain containing 1


F11 receptor
chr11_+_122709205 1.080 NM_019604
CRTAM
cytotoxic and regulatory T cell molecule
chr1_-_156265457 1.075 C1orf85
chromosome 1 open reading frame 85
chr9_-_215892 1.075 NM_152569
C9orf66
chromosome 9 open reading frame 66
chr1_-_27701302 1.067 NM_003665
NM_173452
FCN3

ficolin (collagen/fibrinogen domain containing) 3 (Hakata antigen)

chr7_+_139528951 1.066 NM_001061
NM_001166253
NM_030984
TBXAS1


thromboxane A synthase 1 (platelet)


chr2_-_20527120 1.062 NM_015317
PUM2
pumilio homolog 2 (Drosophila)
chr5_-_180076616 1.060 NM_002020
NM_182925
FLT4

fms-related tyrosine kinase 4

chr19_+_3728373 1.059 NM_014428
TJP3
tight junction protein 3 (zona occludens 3)
chr9_-_4300028 1.057 NM_001042413
GLIS3
GLIS family zinc finger 3
chr8_-_30585442 1.055 NM_000637
NM_001195102
NM_001195103
NM_001195104
GSR



glutathione reductase



chr17_-_29641068 1.053 EVI2B
ecotropic viral integration site 2B
chr6_-_32151996 1.052 NM_001136
NM_001206929
NM_001206932
NM_001206934
NM_001206936
NM_001206940
NM_001206954
NM_001206966
NM_172197
AGER








advanced glycosylation end product-specific receptor








chr19_-_36499583 1.051 NM_001039876
C19orf46
chromosome 19 open reading frame 46
chr6_-_31560497 1.047 NM_001145466
NM_001145467
NM_147130
NCR3


natural cytotoxicity triggering receptor 3


chr12_-_8088629 1.039 NM_006931
SLC2A3
solute carrier family 2 (facilitated glucose transporter), member 3
chr9_+_118916069 1.036 NM_002581
PAPPA
pregnancy-associated plasma protein A, pappalysin 1
chr1_+_220960038 1.036 NM_022746
MARC1
mitochondrial amidoxime reducing component 1
chr17_-_29641094 1.029 NM_006495
EVI2B
ecotropic viral integration site 2B
chr14_-_106610338 1.027 IGHV4-31
IGHG1
immunoglobulin heavy variable 4-31
immunoglobulin heavy constant gamma 1 (G1m marker)
chr19_-_54692132 1.026 MBOAT7
membrane bound O-acyltransferase domain containing 7
chr6_+_64356430 1.023 NM_015153
PHF3
PHD finger protein 3
chr12_-_121736110 1.022 NM_006549
NM_153499
NM_153500
NM_172214
NM_172215
NM_172216
CAMKK2





calcium/calmodulin-dependent protein kinase kinase 2, beta





chr16_+_81812897 1.021 NM_002661
PLCG2
phospholipase C, gamma 2 (phosphatidylinositol-specific)
chr1_-_24239758 1.020 NM_001841
CNR2
cannabinoid receptor 2 (macrophage)
chr20_+_5987897 1.018 NM_001127458
CRLS1
cardiolipin synthase 1
chr8_-_144812920 1.014


chr12_-_21757752 1.011 NM_021957
GYS2
glycogen synthase 2 (liver)
chr8_+_120079423 1.010 NM_006438
COLEC10
collectin sub-family member 10 (C-type lectin)
chr6_+_131958441 1.005 NM_005021
ENPP3
ectonucleotide pyrophosphatase/phosphodiesterase 3
chr4_-_76862094 1.001 NM_001042402
NM_014435
NAAA

N-acylethanolamine acid amidase

chr1_-_12677347 0.991 NM_004753
DHRS3
dehydrogenase/reductase (SDR family) member 3
chr5_-_180076544 0.989 FLT4
fms-related tyrosine kinase 4
chr1_+_24840800 0.987 NM_001251980
NM_001251982
NM_001251985
RCAN3


RCAN family member 3


chr13_-_41593405 0.982 ELF1
E74-like factor 1 (ets domain transcription factor)
chr2_+_143635225 0.980 KYNU
kynureninase
chr2_-_47134945 0.978 MCFD2
multiple coagulation factor deficiency 2
chr11_-_59950498 0.976 NM_022349
NM_152851
MS4A6A

membrane-spanning 4-domains, subfamily A, member 6A

chr6_+_74171453 0.968 NM_001123226
NM_012123
NM_133645
MTO1


mitochondrial translation optimization 1 homolog (S. cerevisiae)


chr3_+_111261039 0.967 CD96
CD96 molecule
chr2_-_216242916 0.965 FN1
fibronectin 1
chr14_-_61748193 0.965


chrY_+_1337692 0.965 NM_001161529
NM_001161531
NM_001161532
NM_006140
NM_172245
NM_172246
NM_172249
CSF2RA






colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)






chr4_+_74270832 0.964 ALB
albumin

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
4.04 4.59e-12 GO:0002376 immune system process
5.39 9.08e-12 GO:0002682 regulation of immune system process
6.46 2.83e-10 GO:0002684 positive regulation of immune system process
6.39 3.49e-10 GO:0050776 regulation of immune response
4.84 4.41e-10 GO:0006955 immune response
8.10 4.86e-10 GO:0050778 positive regulation of immune response
8.24 8.82e-08 GO:0002253 activation of immune response
7.22 2.18e-06 GO:0002694 regulation of leukocyte activation
2.68 2.35e-06 GO:0048583 regulation of response to stimulus
3.86 2.43e-06 GO:0006952 defense response
7.16 2.46e-06 GO:0045321 leukocyte activation
6.95 3.71e-06 GO:0050865 regulation of cell activation
7.71 1.20e-05 GO:0046649 lymphocyte activation
3.51 1.77e-05 GO:0009611 response to wounding
4.59 2.82e-05 GO:0001775 cell activation
7.70 4.46e-05 GO:0002757 immune response-activating signal transduction
6.89 4.55e-05 GO:0051249 regulation of lymphocyte activation
7.53 5.76e-05 GO:0002764 immune response-regulating signaling pathway
6.00 7.77e-05 GO:0001817 regulation of cytokine production
8.21 8.48e-05 GO:0002697 regulation of immune effector process
5.78 1.25e-04 GO:0006954 inflammatory response
9.78 2.89e-04 GO:0002429 immune response-activating cell surface receptor signaling pathway
7.27 2.91e-04 GO:0050863 regulation of T cell activation
11.70 3.29e-04 GO:0002699 positive regulation of immune effector process
9.41 4.03e-04 GO:0002768 immune response-regulating cell surface receptor signaling pathway
28.86 5.08e-04 GO:0050853 B cell receptor signaling pathway
6.86 5.23e-04 GO:0002696 positive regulation of leukocyte activation
7.73 5.77e-04 GO:0002252 immune effector process
6.75 6.19e-04 GO:0050867 positive regulation of cell activation
1.57 8.01e-04 GO:0050896 response to stimulus
16.45 1.27e-03 GO:0045582 positive regulation of T cell differentiation
6.69 2.15e-03 GO:0051251 positive regulation of lymphocyte activation
14.96 2.27e-03 GO:0045621 positive regulation of lymphocyte differentiation
3.17 2.43e-03 GO:0048584 positive regulation of response to stimulus
4.74 3.21e-03 GO:0031347 regulation of defense response
19.59 4.02e-03 GO:0001910 regulation of leukocyte mediated cytotoxicity
10.38 4.05e-03 GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
10.11 4.84e-03 GO:0002250 adaptive immune response
17.69 6.79e-03 GO:0031341 regulation of cell killing
29.25 6.88e-03 GO:0002717 positive regulation of natural killer cell mediated immunity
29.25 6.88e-03 GO:0045954 positive regulation of natural killer cell mediated cytotoxicity
29.25 6.88e-03 GO:0050854 regulation of antigen receptor-mediated signaling pathway
12.42 6.89e-03 GO:0045580 regulation of T cell differentiation
7.70 7.95e-03 GO:0042110 T cell activation
54.83 1.19e-02 GO:0045586 regulation of gamma-delta T cell differentiation
54.83 1.19e-02 GO:0045588 positive regulation of gamma-delta T cell differentiation
7.26 1.23e-02 GO:0045089 positive regulation of innate immune response
4.16 1.31e-02 GO:0045087 innate immune response
2.47 1.33e-02 GO:0051239 regulation of multicellular organismal process
24.37 1.51e-02 GO:0002715 regulation of natural killer cell mediated immunity
24.37 1.51e-02 GO:0042269 regulation of natural killer cell mediated cytotoxicity
10.79 1.57e-02 GO:0045619 regulation of lymphocyte differentiation
8.26 1.84e-02 GO:0050851 antigen receptor-mediated signaling pathway
1.77 1.88e-02 GO:0007165 signal transduction
14.43 1.91e-02 GO:0046634 regulation of alpha-beta T cell activation
47.00 2.08e-02 GO:0046643 regulation of gamma-delta T cell activation
47.00 2.08e-02 GO:0046645 positive regulation of gamma-delta T cell activation
8.09 2.12e-02 GO:0030098 lymphocyte differentiation
3.50 2.23e-02 GO:0080134 regulation of response to stress
21.94 2.36e-02 GO:0009595 detection of biotic stimulus
7.92 2.42e-02 GO:0002683 negative regulation of immune system process
9.98 2.47e-02 GO:0002703 regulation of leukocyte mediated immunity
6.55 2.58e-02 GO:0050870 positive regulation of T cell activation
13.38 2.78e-02 GO:0050871 positive regulation of B cell activation
7.68 2.95e-02 GO:0050670 regulation of lymphocyte proliferation
7.61 3.15e-02 GO:0032944 regulation of mononuclear cell proliferation
41.13 3.30e-02 GO:0002834 regulation of response to tumor cell
41.13 3.30e-02 GO:0002836 positive regulation of response to tumor cell
41.13 3.30e-02 GO:0002837 regulation of immune response to tumor cell
41.13 3.30e-02 GO:0002839 positive regulation of immune response to tumor cell
19.94 3.51e-02 GO:0046638 positive regulation of alpha-beta T cell differentiation
7.39 3.80e-02 GO:0070663 regulation of leukocyte proliferation
1.86 3.87e-02 GO:0048518 positive regulation of biological process
19.08 4.22e-02 GO:0001912 positive regulation of leukocyte mediated cytotoxicity
36.56 4.91e-02 GO:0002833 positive regulation of response to biotic stimulus

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
1.92 7.70e-07 GO:0071944 cell periphery
1.89 2.96e-06 GO:0005886 plasma membrane
2.85 2.21e-05 GO:0005887 integral to plasma membrane
2.27 2.95e-05 GO:0044459 plasma membrane part
2.79 3.32e-05 GO:0031226 intrinsic to plasma membrane
1.63 1.85e-04 GO:0016021 integral to membrane
1.62 1.86e-04 GO:0031224 intrinsic to membrane
1.54 2.27e-04 GO:0044425 membrane part
1.40 3.71e-03 GO:0016020 membrane
3.61 1.77e-02 GO:0009986 cell surface

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
2.22 1.94e-04 GO:0004871 signal transducer activity
2.22 1.94e-04 GO:0060089 molecular transducer activity
16.45 2.64e-04 GO:0003823 antigen binding
2.30 7.72e-04 GO:0004872 receptor activity
2.41 4.24e-03 GO:0004888 transmembrane receptor activity
19.08 8.76e-03 GO:0001608 nucleotide receptor activity, G-protein coupled
19.08 8.76e-03 GO:0045028 purinergic nucleotide receptor activity, G-protein coupled
32.90 1.45e-02 GO:0032393 MHC class I receptor activity
14.63 2.58e-02 GO:0001614 purinergic nucleotide receptor activity
14.63 2.58e-02 GO:0016502 nucleotide receptor activity
12.91 4.24e-02 GO:0035586 purinergic receptor activity