Motif ID: FOXL1.p2

Z-value: 1.779


Transcription factors associated with FOXL1.p2:

Gene SymbolEntrez IDGene Name
FOXL1 2300 forkhead box L1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
FOXL1hg19_v1_chr16_+_86612114_86612114-0.105.9e-01Click!


Activity profile for motif FOXL1.p2.

activity profile for motif FOXL1.p2


Sorted Z-values histogram for motif FOXL1.p2

Sorted Z-values for motif FOXL1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of FOXL1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr4_-_65275000 14.488 NM_001010874
 TECRL
trans-2,3-enoyl-CoA reductase-like
chrX_-_33229428 9.313 NM_004006
 DMD
dystrophin
chr7_-_113559048 8.948 NM_002711
 PPP1R3A
protein phosphatase 1, regulatory subunit 3A
chr7_+_80267972 8.873 CD36
CD36 molecule (thrombospondin receptor)
chr7_+_80267922 6.860 CD36
CD36 molecule (thrombospondin receptor)
chr16_-_31439650 6.820 NM_005205
 COX6A2
cytochrome c oxidase subunit VIa polypeptide 2
chr7_+_80267782 6.416 NM_000072
NM_001001548
 CD36

CD36 molecule (thrombospondin receptor)

chr6_-_123957941 6.351 NM_001251987
NM_006073
 TRDN

triadin

chr11_-_19223516 5.986 NM_001127656
NM_003476
 CSRP3

cysteine and glycine-rich protein 3 (cardiac LIM protein)

chrX_+_99839789 5.726 NM_022144
 TNMD
tenomodulin
chr6_-_139613114 5.634 NM_153235
 TXLNB
taxilin beta
chr8_-_82395401 5.172 NM_001442
 FABP4
fatty acid binding protein 4, adipocyte
chr12_+_81101407 5.136 NM_002469
 MYF6
myogenic factor 6 (herculin)
chr9_+_103340335 5.024 NM_001018116
 MURC
muscle-related coiled-coil protein
chrX_-_15332680 4.924 NM_001012428
 ASB11
ankyrin repeat and SOCS box containing 11
chr3_-_196242190 4.905 NM_001077657
 C3orf43
chromosome 3 open reading frame 43
chr17_+_37821598 4.864 NM_003673
 TCAP
titin-cap (telethonin)
chr10_-_69425356 4.695 NM_001127384
 CTNNA3
catenin (cadherin-associated protein), alpha 3
chr4_+_76995862 4.655 NM_001130016
NM_001179
 ART3

ADP-ribosyltransferase 3

chr7_+_80275967 4.617 CD36
CD36 molecule (thrombospondin receptor)

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 36 entries
Enrichment   P-value GO Accession GO Term
38.39 1.76e-03 GO:0045214 sarcomere organization
34.24 3.78e-13 GO:0030049 muscle filament sliding
34.24 3.78e-13 GO:0033275 actin-myosin filament sliding
33.34 5.48e-13 GO:0070252 actin-mediated cell contraction
31.38 1.96e-11 GO:0006941 striated muscle contraction
30.16 2.30e-05 GO:0030239 myofibril assembly
26.91 7.67e-13 GO:0030048 actin filament-based movement
26.39 7.18e-04 GO:0003015 heart process
26.39 7.18e-04 GO:0060047 heart contraction
26.39 9.36e-03 GO:0060048 cardiac muscle contraction
24.84 1.21e-02 GO:0043462 regulation of ATPase activity
23.46 1.20e-04 GO:0031032 actomyosin structure organization
21.99 1.91e-03 GO:0003229 ventricular cardiac muscle tissue development
21.99 1.91e-03 GO:0055010 ventricular cardiac muscle tissue morphogenesis
20.43 2.89e-04 GO:0055008 cardiac muscle tissue morphogenesis
19.80 3.53e-04 GO:0060415 muscle tissue morphogenesis
17.37 3.15e-22 GO:0006936 muscle contraction
16.67 1.03e-03 GO:0048644 muscle organ morphogenesis
16.57 1.35e-22 GO:0003012 muscle system process
16.50 8.50e-03 GO:0003208 cardiac ventricle morphogenesis

Gene overrepresentation in compartment category:

Showing 1 to 20 of 28 entries
Enrichment   P-value GO Accession GO Term
63.33 1.27e-03 GO:0033018 sarcoplasmic reticulum lumen
45.24 4.38e-03 GO:0005861 troponin complex
35.19 1.04e-02 GO:0005916 fascia adherens
32.48 8.02e-04 GO:0005865 striated muscle thin filament
32.48 8.02e-04 GO:0031672 A band
29.32 8.59e-05 GO:0005859 muscle myosin complex
29.32 8.59e-05 GO:0032982 myosin filament
26.39 1.53e-04 GO:0016460 myosin II complex
26.39 2.66e-02 GO:0014704 intercalated disc
26.39 2.66e-02 GO:0043034 costamere
26.39 2.66e-02 GO:0044291 cell-cell contact zone
23.70 2.58e-22 GO:0030017 sarcomere
23.36 2.22e-25 GO:0044449 contractile fiber part
22.75 4.52e-25 GO:0030016 myofibril
21.46 2.20e-24 GO:0043292 contractile fiber
17.60 2.30e-06 GO:0031674 I band
16.67 2.19e-04 GO:0030018 Z disc
16.50 1.81e-03 GO:0005913 cell-cell adherens junction
14.27 3.78e-03 GO:0016529 sarcoplasmic reticulum
13.89 4.32e-03 GO:0016528 sarcoplasm

Gene overrepresentation in function category:

Showing 1 to 7 of 7 entries
Enrichment   P-value GO Accession GO Term
70.37 3.86e-02 GO:0031014 troponin T binding
45.24 4.13e-03 GO:0031432 titin binding
31.91 1.26e-14 GO:0008307 structural constituent of muscle
22.62 4.09e-02 GO:0005523 tropomyosin binding
8.07 3.77e-13 GO:0003779 actin binding
6.15 1.48e-13 GO:0008092 cytoskeletal protein binding
3.30 1.33e-03 GO:0005198 structural molecule activity