Motif ID: FOXO1,3,4.p2

Z-value: 1.431


Transcription factors associated with FOXO1,3,4.p2:

Gene SymbolEntrez IDGene Name
FOXO1 2308 forkhead box O1
FOXO3 2309 forkhead box O3
FOXO4 4303 forkhead box O4

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
FOXO3hg19_v1_chr6_+_108882104_1088824110.655.5e-05Click!
FOXO4hg19_v1_chrX_+_70315637_703163780.522.2e-03Click!
FOXO1hg19_v1_chr13_-_41240607_412408180.441.2e-02Click!


Activity profile for motif FOXO1,3,4.p2.

activity profile for motif FOXO1,3,4.p2


Sorted Z-values histogram for motif FOXO1,3,4.p2

Sorted Z-values for motif FOXO1,3,4.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of FOXO1,3,4.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr2_+_168043792 5.569 NM_001199144
NM_001199145
 XIRP2

xin actin-binding repeat containing 2

chr3_-_196242190 5.075 NM_001077657
 C3orf43
chromosome 3 open reading frame 43
chr12_-_111358353 4.866 NM_000432
 MYL2
myosin, light chain 2, regulatory, cardiac, slow
chr17_+_37821598 4.009 NM_003673
 TCAP
titin-cap (telethonin)
chr2_-_142889269 3.416 NM_018557
 LRP1B
low density lipoprotein receptor-related protein 1B
chr17_-_67057046 3.387 NM_080283
 ABCA9
ATP-binding cassette, sub-family A (ABC1), member 9
chr4_+_41614725 3.271 LIMCH1
LIM and calponin homology domains 1
chr18_-_56296188 3.123 NM_052947
 ALPK2
alpha-kinase 2
chr4_+_119947816 3.117 SYNPO2
synaptopodin 2
chr4_+_119948273 2.811 SYNPO2
synaptopodin 2
chr10_+_115310589 2.791 NM_001177660
 HABP2
hyaluronan binding protein 2
chr5_+_137203559 2.766 MYOT
myotilin
chr3_+_186560478 2.725 ADIPOQ
adiponectin, C1Q and collagen domain containing
chr7_-_95225802 2.635 NM_002612
 PDK4
pyruvate dehydrogenase kinase, isozyme 4
chr3_+_186560462 2.631 NM_001177800
NM_004797
 ADIPOQ

adiponectin, C1Q and collagen domain containing

chr4_-_186697065 2.599 NM_001145673
 SORBS2
sorbin and SH3 domain containing 2
chr19_+_13134782 2.560 NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr5_+_137203544 2.526 NM_001135940
NM_006790
 MYOT

myotilin

chr10_+_123923104 2.492 NM_006997
NM_206860
 TACC2

transforming, acidic coiled-coil containing protein 2

chr4_+_41614911 2.435 NM_001112719
NM_001112720
 LIMCH1

LIM and calponin homology domains 1


Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 4 of 4 entries
Enrichment   P-value GO Accession GO Term
22.35 1.78e-02 GO:0031032 actomyosin structure organization
8.19 1.48e-02 GO:0060537 muscle tissue development
7.64 6.33e-03 GO:0006936 muscle contraction
7.02 1.17e-02 GO:0003012 muscle system process

Gene overrepresentation in compartment category:

Showing 1 to 4 of 4 entries
Enrichment   P-value GO Accession GO Term
12.32 3.29e-05 GO:0030017 sarcomere
10.68 9.85e-05 GO:0044449 contractile fiber part
10.41 1.20e-04 GO:0030016 myofibril
9.82 1.88e-04 GO:0043292 contractile fiber

Gene overrepresentation in function category:

Showing 1 to 3 of 3 entries
Enrichment   P-value GO Accession GO Term
17.54 1.11e-03 GO:0008307 structural constituent of muscle
4.81 5.39e-03 GO:0003779 actin binding
4.11 9.23e-04 GO:0008092 cytoskeletal protein binding