Motif ID: GATA1..3.p2

Z-value: 2.844


Transcription factors associated with GATA1..3.p2:

Gene SymbolEntrez IDGene Name
GATA1 2623 GATA binding protein 1 (globin transcription factor 1)
GATA2 2624 GATA binding protein 2
GATA3 2625 GATA binding protein 3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
GATA3hg19_v1_chr10_+_8097350_8097617-0.373.6e-02Click!
GATA2hg19_v1_chr3_-_128207366_1282073740.327.9e-02Click!
GATA1hg19_v1_chrX_+_48644961_48645015-0.019.4e-01Click!


Activity profile for motif GATA1..3.p2.

activity profile for motif GATA1..3.p2


Sorted Z-values histogram for motif GATA1..3.p2

Sorted Z-values for motif GATA1..3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of GATA1..3.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr15_+_91769329 8.492 SV2B
synaptic vesicle glycoprotein 2B
chr3_+_181417387 6.264 SOX2-OT
SOX2 overlapping transcript (non-protein coding)
chr5_-_141993691 5.937 NM_033137
 FGF1
fibroblast growth factor 1 (acidic)
chr5_+_175308843 5.614 CPLX2
complexin 2
chr14_-_24047774 5.269 JPH4
junctophilin 4
chr5_-_160112266 5.010 ATP10B
ATPase, class V, type 10B
chr3_-_195310985 4.989 NM_001647
 APOD
apolipoprotein D
chrX_+_38420690 4.808 NM_004615
 TSPAN7
tetraspanin 7
chr14_-_24047993 4.685 NM_001146028
NM_032452
 JPH4

junctophilin 4

chr7_-_31380507 4.676 NM_022728
 NEUROD6
neurogenic differentiation 6
chr4_+_134073180 4.672 PCDH10
protocadherin 10
chr16_-_15835382 4.601 MYH11
myosin, heavy chain 11, smooth muscle
chr3_-_195310770 4.508 APOD
apolipoprotein D
chr15_+_43809805 4.463 NM_002373
 MAP1A
microtubule-associated protein 1A
chr15_-_93616358 4.424 NM_001166286
 RGMA
RGM domain family, member A
chrX_+_70364680 4.401 NM_001166660
NM_018977
NM_181303
 NLGN3


neuroligin 3


chr5_-_149669187 4.330 CAMK2A
calcium/calmodulin-dependent protein kinase II alpha
chr14_+_65007418 4.277 HSPA2
heat shock 70kDa protein 2
chr11_+_33563772 4.260 NM_012194
 C11orf41
chromosome 11 open reading frame 41
chrX_+_53078505 4.249 NM_018969
 GPR173
G protein-coupled receptor 173

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 68 entries
Enrichment   P-value GO Accession GO Term
12.58 6.54e-03 GO:0051966 regulation of synaptic transmission, glutamatergic
9.98 5.93e-03 GO:0007215 glutamate signaling pathway
6.29 1.57e-02 GO:0032412 regulation of ion transmembrane transporter activity
6.05 2.17e-02 GO:0022898 regulation of transmembrane transporter activity
5.73 3.45e-02 GO:0034765 regulation of ion transmembrane transport
4.57 1.45e-03 GO:0050890 cognition
4.54 8.14e-03 GO:0006836 neurotransmitter transport
4.46 2.27e-02 GO:0045761 regulation of adenylate cyclase activity
4.36 2.81e-02 GO:0031279 regulation of cyclase activity
4.33 1.39e-02 GO:0007611 learning or memory
4.28 3.45e-02 GO:0051339 regulation of lyase activity
4.28 3.45e-02 GO:0051924 regulation of calcium ion transport
4.21 4.15e-03 GO:0042391 regulation of membrane potential
4.17 2.08e-02 GO:0030817 regulation of cAMP biosynthetic process
4.16 1.02e-02 GO:0030802 regulation of cyclic nucleotide biosynthetic process
4.16 1.02e-02 GO:0030808 regulation of nucleotide biosynthetic process
4.14 2.29e-02 GO:0030814 regulation of cAMP metabolic process
4.06 1.37e-02 GO:0030799 regulation of cyclic nucleotide metabolic process
3.93 1.98e-02 GO:0006814 sodium ion transport
3.89 4.40e-02 GO:0010959 regulation of metal ion transport

Gene overrepresentation in compartment category:

Showing 1 to 20 of 37 entries
Enrichment   P-value GO Accession GO Term
26.72 2.12e-02 GO:0033268 node of Ranvier
17.82 9.48e-05 GO:0001518 voltage-gated sodium channel complex
14.25 4.78e-04 GO:0034706 sodium channel complex
11.88 2.72e-04 GO:0005891 voltage-gated calcium channel complex
9.83 2.34e-04 GO:0034704 calcium channel complex
7.42 1.76e-04 GO:0043197 dendritic spine
7.13 2.63e-04 GO:0044309 neuron spine
6.74 1.63e-02 GO:0016529 sarcoplasmic reticulum
6.56 1.95e-02 GO:0016528 sarcoplasm
5.28 3.13e-07 GO:0034703 cation channel complex
4.96 3.12e-03 GO:0014069 postsynaptic density
4.69 1.27e-02 GO:0033267 axon part
4.36 8.46e-07 GO:0030425 dendrite
4.36 4.83e-03 GO:0030017 sarcomere
4.35 4.76e-04 GO:0043292 contractile fiber
4.32 6.06e-15 GO:0045202 synapse
4.19 1.74e-05 GO:0043025 neuronal cell body
4.10 4.34e-03 GO:0044449 contractile fiber part
4.07 2.82e-05 GO:0044297 cell body
4.00 2.32e-12 GO:0043005 neuron projection

Gene overrepresentation in function category:

Showing 1 to 20 of 22 entries
Enrichment   P-value GO Accession GO Term
15.27 3.82e-04 GO:0005248 voltage-gated sodium channel activity
9.59 1.77e-03 GO:0005245 voltage-gated calcium channel activity
8.91 3.04e-03 GO:0008066 glutamate receptor activity
6.74 2.12e-02 GO:0008227 G-protein coupled amine receptor activity
5.09 3.15e-03 GO:0005262 calcium channel activity
5.02 1.01e-06 GO:0022843 voltage-gated cation channel activity
3.81 1.09e-04 GO:0005244 voltage-gated ion channel activity
3.81 1.09e-04 GO:0022832 voltage-gated channel activity
3.65 2.53e-06 GO:0005261 cation channel activity
3.43 2.74e-06 GO:0022836 gated channel activity
2.86 6.00e-05 GO:0022838 substrate-specific channel activity
2.81 1.37e-04 GO:0005216 ion channel activity
2.77 1.17e-04 GO:0015267 channel activity
2.76 1.24e-04 GO:0022803 passive transmembrane transporter activity
2.46 1.66e-04 GO:0008324 cation transmembrane transporter activity
2.12 1.37e-03 GO:0015075 ion transmembrane transporter activity
1.99 2.52e-03 GO:0022891 substrate-specific transmembrane transporter activity
1.93 3.84e-03 GO:0022857 transmembrane transporter activity
1.87 3.16e-02 GO:0004930 G-protein coupled receptor activity
1.79 2.58e-02 GO:0022892 substrate-specific transporter activity