Motif ID: GCAGCAU

Z-value: 1.078


Mature miRNA associated with seed GCAGCAU:

NamemiRBase Accession
hsa-miR-103a MIMAT0000101
hsa-miR-107 MIMAT0000104



Activity profile for motif GCAGCAU.

activity profile for motif GCAGCAU


Sorted Z-values histogram for motif GCAGCAU

Sorted Z-values for motif GCAGCAU



Network of associatons between targets according to the STRING database.



First level regulatory network of GCAGCAU

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_-_91006460 3.259 NM_021813
BACH2
BTB and CNC homology 1, basic leucine zipper transcription factor 2
chr14_-_95599794 3.103 NM_001195573
DICER1
dicer 1, ribonuclease type III
chr6_-_91006580 3.089 NM_001170794
BACH2
BTB and CNC homology 1, basic leucine zipper transcription factor 2
chr1_+_206680863 3.072 NM_182663
NM_182664
RASSF5

Ras association (RalGDS/AF-6) domain family member 5

chr6_-_108145507 3.005 NM_198081
SCML4
sex comb on midleg-like 4 (Drosophila)
chr1_+_90287404 2.574 NM_018103
LRRC8D
leucine rich repeat containing 8 family, member D
chrX_+_49832214 2.477 NM_000084
CLCN5
chloride channel 5
chr3_-_27763784 2.352 NM_005442
EOMES
eomesodermin
chr1_+_90286469 2.321 NM_001134479
LRRC8D
leucine rich repeat containing 8 family, member D
chr1_+_206730456 2.188 NM_182665
RASSF5
Ras association (RalGDS/AF-6) domain family member 5
chr3_-_112218383 2.123 NM_001085357
NM_181780
BTLA

B and T lymphocyte associated

chr12_+_104850641 2.062 NM_001173982
NM_018413
CHST11

carbohydrate (chondroitin 4) sulfotransferase 11

chr5_-_147162251 2.052 NM_014790
JAKMIP2
janus kinase and microtubule interacting protein 2
chr22_-_17602142 1.916 NM_031890
NM_001163079
CECR6

cat eye syndrome chromosome region, candidate 6

chr14_-_95608054 1.881 NM_030621
DICER1
dicer 1, ribonuclease type III
chr17_+_30813928 1.798 NM_003885
CDK5R1
cyclin-dependent kinase 5, regulatory subunit 1 (p35)
chrX_+_30671456 1.731 NM_000167
NM_001128127
NM_001205019
NM_203391
GK



glycerol kinase



chr7_-_105319608 1.721 NM_138495
ATXN7L1
ataxin 7-like 1
chr14_-_95623665 1.696 NM_177438
DICER1
dicer 1, ribonuclease type III
chrX_-_131623994 1.685 NM_001170704
MBNL3
muscleblind-like 3 (Drosophila)
chr3_-_164914448 1.649 NM_014926
SLITRK3
SLIT and NTRK-like family, member 3
chr5_+_67586466 1.646 NM_181504
PIK3R1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr8_-_82024277 1.646 NM_018440
PAG1
phosphoprotein associated with glycosphingolipid microdomains 1
chr5_+_82767492 1.619 NM_001126336
NM_001164097
NM_001164098
NM_004385
VCAN



versican



chrX_-_109561314 1.616 NM_001025580
NM_015365
AMMECR1

Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1

chrX_-_131573638 1.609 NM_018388
NM_133486
MBNL3

muscleblind-like 3 (Drosophila)

chr12_+_68042493 1.607 NM_003583
NM_006482
DYRK2

dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2

chr17_+_29718641 1.587 NM_032932
RAB11FIP4
RAB11 family interacting protein 4 (class II)
chr6_+_34433849 1.577 NM_020804
PACSIN1
protein kinase C and casein kinase substrate in neurons 1
chr4_-_153273683 1.569 NM_018315
FBXW7
F-box and WD repeat domain containing 7
chr1_-_240775448 1.559 NM_022469
GREM2
gremlin 2
chr6_+_34482646 1.492 NM_001199583
PACSIN1
protein kinase C and casein kinase substrate in neurons 1
chr4_+_4387982 1.485 NM_001040101
NM_014392
D4S234E

DNA segment on chromosome 4 (unique) 234 expressed sequence

chr22_+_40573879 1.474 NM_001162501
NM_015088
TNRC6B

trinucleotide repeat containing 6B

chr10_-_94050799 1.469 NM_014912
CPEB3
cytoplasmic polyadenylation element binding protein 3
chrX_-_109683457 1.461 NM_001171689
AMMECR1
Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1
chr12_-_57400199 1.450 NM_014830
ZBTB39
zinc finger and BTB domain containing 39
chrX_-_131547536 1.418 NM_001170701
NM_001170702
NM_001170703
MBNL3


muscleblind-like 3 (Drosophila)


chr18_+_29598444 1.356 NM_017831
RNF125
ring finger protein 125
chr1_-_156785938 1.349 NM_001161443
SH2D2A
SH2 domain containing 2A
chr7_-_92465929 1.347 NM_001145306
CDK6
cyclin-dependent kinase 6
chr2_+_203499819 1.335 NM_173511
FAM117B
family with sequence similarity 117, member B
chr3_+_43328001 1.325 NM_001100594
NM_017719
SNRK

SNF related kinase

chr15_+_89631380 1.319 NM_007011
NM_152924
ABHD2

abhydrolase domain containing 2

chrX_-_20284708 1.311 NM_004586
RPS6KA3
ribosomal protein S6 kinase, 90kDa, polypeptide 3
chr7_-_92463211 1.300 NM_001259
CDK6
cyclin-dependent kinase 6
chr4_+_108745718 1.271 NM_001136258
SGMS2
sphingomyelin synthase 2
chr22_-_39151457 1.256 NM_001199580
SUN2
Sad1 and UNC84 domain containing 2
chr15_+_91411884 1.255 NM_002569
FURIN
furin (paired basic amino acid cleaving enzyme)
chr3_+_152017193 1.253 NM_207293
NM_207294
NM_207295
NM_207296
NM_207297
MBNL1




muscleblind-like (Drosophila)




chr15_-_60884615 1.243 NM_134262
RORA
RAR-related orphan receptor A
chr22_+_45560529 1.239 NM_153645
NUP50
nucleoporin 50kDa
chr8_-_67525426 1.223 NM_001080416
NM_001144755
MYBL1

LOC645895
v-myb myeloblastosis viral oncogene homolog (avian)-like 1

uncharacterized LOC645895
chr10_-_88854686 1.214 NM_005271
GLUD1
glutamate dehydrogenase 1
chr2_-_172087823 1.212 NM_001136554
TLK1
tousled-like kinase 1
chr15_-_61521478 1.211 NM_134261
RORA
RAR-related orphan receptor A
chrX_+_49687212 1.208 NM_001127898
NM_001127899
CLCN5

chloride channel 5

chr7_+_143078358 1.192 NM_001010972
NM_003461
ZYX

zyxin

chr7_+_6144504 1.187 NM_032172
USP42
ubiquitin specific peptidase 42
chr15_-_56535475 1.167 NM_022841
RFX7
regulatory factor X, 7
chr22_-_39152008 1.165 NM_001199579
NM_015374
SUN2

Sad1 and UNC84 domain containing 2

chr19_+_1941157 1.150 NM_001319
CSNK1G2
casein kinase 1, gamma 2
chr14_+_103243813 1.135 NM_001199427
NM_003300
NM_145725
NM_145726
TRAF3



TNF receptor-associated factor 3



chr22_+_40440664 1.130 NM_001024843
TNRC6B
trinucleotide repeat containing 6B
chr12_-_39836760 1.126 NM_001173463
NM_001173464
NM_001173465
NM_017641
KIF21A



kinesin family member 21A



chr3_+_151985828 1.122 NM_021038
NM_207292
MBNL1

muscleblind-like (Drosophila)

chr12_-_53994783 1.119 NM_001130059
ATF7
activating transcription factor 7
chr11_-_35441501 1.116 NM_001195728
NM_001252652
SLC1A2

solute carrier family 1 (glial high affinity glutamate transporter), member 2

chr20_+_2276612 1.109 NM_003245
TGM3
transglutaminase 3 (E polypeptide, protein-glutamine-gamma-glutamyltransferase)
chr2_-_206950895 1.108 NM_017759
INO80D
INO80 complex subunit D
chr5_+_102465256 1.107 NM_015216
PPIP5K2
diphosphoinositol pentakisphosphate kinase 2
chr17_-_28257017 1.107 NM_033389
SSH2
slingshot homolog 2 (Drosophila)
chr22_-_32146119 1.106 NM_173566
PRR14L
proline rich 14-like
chr14_+_53196852 1.099 NM_001130701
NM_145251
STYX

serine/threonine/tyrosine interacting protein

chr1_+_162466963 1.092 NM_001184763
UHMK1
U2AF homology motif (UHM) kinase 1
chr10_+_11206928 1.075 NM_001025076
NM_001083591
CELF2

CUGBP, Elav-like family member 2

chr1_+_167298280 1.068 NM_001198783
POU2F1
POU class 2 homeobox 1
chr1_+_233463513 1.065 NM_032435
KIAA1804
mixed lineage kinase 4
chr4_-_153456152 1.063 NM_033632
FBXW7
F-box and WD repeat domain containing 7
chr1_-_108231122 1.060 NM_001079874
VAV3
vav 3 guanine nucleotide exchange factor
chr2_-_171923482 1.057 NM_001136555
TLK1
tousled-like kinase 1
chr3_+_88188261 1.038 NM_018293
ZNF654
zinc finger protein 654
chr7_-_105516923 1.036 NM_020725
NM_152749
ATXN7L1

ataxin 7-like 1

chr2_+_44066102 1.033 NM_022437
ABCG8
ATP-binding cassette, sub-family G (WHITE), member 8
chr8_-_81083660 1.027 NM_001025253
NM_005079
TPD52

tumor protein D52

chr20_+_35201948 1.026 NM_021809
TGIF2
TGFB-induced factor homeobox 2
chr8_-_80993009 1.021 NM_001025252
TPD52
tumor protein D52
chr7_-_139477437 1.018 NM_001113239
NM_022740
HIPK2

homeodomain interacting protein kinase 2

chr7_-_139876718 1.017 NM_030647
JHDM1D
jumonji C domain containing histone demethylase 1 homolog D (S. cerevisiae)
chr5_+_67588395 1.016 NM_001242466
PIK3R1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr15_-_34629044 1.014 NM_001042497
NM_133647
SLC12A6

solute carrier family 12 (potassium/chloride transporters), member 6

chr2_-_160472960 1.013 NM_013450
BAZ2B
bromodomain adjacent to zinc finger domain, 2B
chr18_+_55019720 1.011 NM_015879
ST8SIA3
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
chr10_+_98592658 1.005 NM_032440
LCOR
ligand dependent nuclear receptor corepressor
chr3_+_119187782 1.004 NM_152305
POGLUT1
protein O-glucosyltransferase 1
chr14_-_53258329 0.994 NM_198066
GNPNAT1
glucosamine-phosphate N-acetyltransferase 1
chr1_-_156786500 0.989 NM_001161441
NM_001161442
NM_001161444
NM_003975
SH2D2A



SH2 domain containing 2A



chr12_-_9913415 0.988 NM_001781
CD69
CD69 molecule
chr10_-_94003002 0.980 NM_001178137
CPEB3
cytoplasmic polyadenylation element binding protein 3
chr10_+_11047253 0.966 NM_001025077
CELF2
CUGBP, Elav-like family member 2
chr5_-_98262217 0.961 NM_001270
CHD1
chromodomain helicase DNA binding protein 1
chr5_+_67584251 0.959 NM_181524
PIK3R1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr11_-_35441099 0.954 NM_004171
SLC1A2
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr17_-_65241305 0.951 NM_014877
HELZ
helicase with zinc finger
chr20_+_35202956 0.947 NM_001199535
NM_001199515
TGIF2-C20ORF24
TGIF2
TGIF2-C20orf24 readthrough
TGFB-induced factor homeobox 2
chr2_+_85804613 0.935 NM_003761
VAMP8
vesicle-associated membrane protein 8 (endobrevin)
chr14_+_103801160 0.928 NM_183004
EIF5
eukaryotic translation initiation factor 5
chr17_-_27224708 0.925 NM_004475
FLOT2
flotillin 2
chr7_+_30323922 0.924 NM_147128
ZNRF2
zinc and ring finger 2
chr1_-_108507474 0.916 NM_006113
VAV3
vav 3 guanine nucleotide exchange factor
chr18_+_60190657 0.913 NM_017742
ZCCHC2
zinc finger, CCHC domain containing 2
chr17_-_73258441 0.909 NM_001172703
NM_001172704
GGA3

golgi-associated, gamma adaptin ear containing, ARF binding protein 3

chr9_+_129622935 0.903 NM_001099270
ZBTB34
zinc finger and BTB domain containing 34
chr17_-_80023679 0.903 NM_022156
DUS1L
dihydrouridine synthase 1-like (S. cerevisiae)
chr22_+_45559725 0.903 NM_007172
NUP50
nucleoporin 50kDa
chr7_+_28475233 0.901 NM_004904
CREB5
cAMP responsive element binding protein 5
chr16_-_48644087 0.894 NM_153029
N4BP1
NEDD4 binding protein 1
chr9_-_127905715 0.892 NM_001144877
NM_173690
SCAI

suppressor of cancer cell invasion

chr2_+_45878912 0.891 NM_005400
PRKCE
protein kinase C, epsilon
chr4_-_153303663 0.891 NM_001013415
FBXW7
F-box and WD repeat domain containing 7
chr1_-_173962050 0.889 NM_172071
RC3H1
ring finger and CCCH-type domains 1
chr1_+_26737232 0.887 NM_024674
LIN28A
lin-28 homolog A (C. elegans)
chr1_-_220101925 0.886 NM_018713
SLC30A10
solute carrier family 30, member 10
chr14_+_57046490 0.884 NM_017799
C14orf101
chromosome 14 open reading frame 101
chr3_+_14989076 0.877 NM_003298
NR2C2
nuclear receptor subfamily 2, group C, member 2
chrX_-_131351917 0.876 NM_021183
RAP2C
RAP2C, member of RAS oncogene family
chr20_+_35201854 0.866 NM_001199513
NM_001199514
TGIF2

TGFB-induced factor homeobox 2

chr10_+_92980322 0.865 NM_032373
PCGF5
polycomb group ring finger 5
chr8_+_32504250 0.864 NM_013959
NRG1
neuregulin 1
chr4_-_78740508 0.862 NM_144571
CNOT6L
CCR4-NOT transcription complex, subunit 6-like
chr12_+_57522247 0.853 NM_002332
LRP1
low density lipoprotein receptor-related protein 1
chr2_-_16847070 0.839 NM_030797
FAM49A
family with sequence similarity 49, member A
chr17_+_26698986 0.838 NM_015077
SARM1
sterile alpha and TIR motif containing 1
chr22_-_42017032 0.837 NM_015704
PPPDE2
PPPDE peptidase domain containing 2
chr22_+_50781717 0.829 NM_001242898
NM_001242899
NM_001242900
NM_014678
PPP6R2



protein phosphatase 6, regulatory subunit 2



chr3_+_63884074 0.829 NM_001177387
ATXN7
ataxin 7
chr15_+_86220267 0.824 NM_144767
AKAP13
A kinase (PRKA) anchor protein 13
chr21_-_16437125 0.823 NM_003489
NRIP1
nuclear receptor interacting protein 1
chr17_-_79479831 0.819 NM_001199954
NM_001614
ACTG1

actin, gamma 1

chr16_+_9185534 0.813 NM_014117
C16orf72
chromosome 16 open reading frame 72
chr12_-_49449106 0.809 NM_003482
MLL2
myeloid/lymphoid or mixed-lineage leukemia 2
chr7_+_28725597 0.807 NM_001011666
CREB5
cAMP responsive element binding protein 5
chr15_-_34610928 0.805 NM_005135
SLC12A6
solute carrier family 12 (potassium/chloride transporters), member 6
chr5_-_111091947 0.804 NM_001142483
C5orf13
chromosome 5 open reading frame 13
chr2_-_39347562 0.802 NM_005633
SOS1
son of sevenless homolog 1 (Drosophila)
chr12_-_57030083 0.801 NM_013449
BAZ2A
bromodomain adjacent to zinc finger domain, 2A
chr17_-_27621163 0.789 NM_020772
NUFIP2
nuclear fragile X mental retardation protein interacting protein 2
chr4_+_3076236 0.785 NM_002111
HTT
huntingtin
chr10_+_11059854 0.785 NM_006561
CELF2
CUGBP, Elav-like family member 2
chr2_-_219925237 0.784 NM_002181
IHH
Indian hedgehog
chr15_-_34629941 0.779 NM_001042494
NM_001042496
SLC12A6

solute carrier family 12 (potassium/chloride transporters), member 6

chr4_+_57775064 0.770 NM_001193508
REST
RE1-silencing transcription factor
chr12_+_105501448 0.768 NM_015275
KIAA1033
KIAA1033
chr8_-_57123858 0.766 NM_001114634
NM_001114635
NM_002655
PLAG1


pleiomorphic adenoma gene 1


chr16_+_50186809 0.764 NM_001040284
NM_001040285
PAPD5

PAP associated domain containing 5

chr7_+_28452143 0.761 NM_182898
CREB5
cAMP responsive element binding protein 5
chr1_-_151300168 0.761 NM_001198774
PI4KB
phosphatidylinositol 4-kinase, catalytic, beta
chr4_+_174089889 0.760 NM_017423
GALNT7
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 7 (GalNAc-T7)
chr1_+_36273786 0.760 NM_017629
EIF2C4
eukaryotic translation initiation factor 2C, 4
chr9_-_139010716 0.760 NM_152833
C9orf69
chromosome 9 open reading frame 69
chr9_+_115513050 0.752 NM_001012994
SNX30
sorting nexin family member 30
chr15_-_34630203 0.747 NM_001042495
SLC12A6
solute carrier family 12 (potassium/chloride transporters), member 6
chr2_-_201936389 0.743 NM_173822
FAM126B
family with sequence similarity 126, member B
chr12_-_46384365 0.741 NM_004719
SCAF11
SR-related CTD-associated factor 11
chr11_+_77300679 0.739 NM_173039
AQP11
aquaporin 11
chr3_-_13921617 0.738 NM_004625
WNT7A
wingless-type MMTV integration site family, member 7A
chr1_-_151300132 0.738 NM_001198773
NM_001198775
NM_002651
PI4KB


phosphatidylinositol 4-kinase, catalytic, beta


chr12_+_104359557 0.737 NM_003211
TDG
thymine-DNA glycosylase
chr12_-_58240746 0.737 NM_005730
CTDSP2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2
chr11_-_129062092 0.736 NM_001142685
ARHGAP32
Rho GTPase activating protein 32
chr10_+_98592015 0.731 NM_001170765
NM_001170766
LCOR

ligand dependent nuclear receptor corepressor

chr9_+_33817168 0.721 NM_017811
UBE2R2
ubiquitin-conjugating enzyme E2R 2
chr16_-_90039239 0.720 NM_145039
CENPBD1
CENPB DNA-binding domains containing 1
chr4_+_140222668 0.720 NM_057175
NAA15
N(alpha)-acetyltransferase 15, NatA auxiliary subunit
chr17_+_30264039 0.715 NM_015355
SUZ12
suppressor of zeste 12 homolog (Drosophila)
chrX_-_118827322 0.712 NM_015129
NM_145799
NM_145800
NM_145802
SEPT6



septin 6



chr2_+_208576239 0.708 NM_001142300
NM_152523
CCNYL1

cyclin Y-like 1

chr3_+_63953419 0.704 NM_001128149
ATXN7
ataxin 7
chr5_-_59783885 0.700 NM_001165899
PDE4D
phosphodiesterase 4D, cAMP-specific
chr14_+_32546445 0.696 NM_001030055
NM_001173
ARHGAP5

Rho GTPase activating protein 5

chr8_-_74791098 0.695 NM_001001481
NM_018299
UBE2W

ubiquitin-conjugating enzyme E2W (putative)

chr17_+_61699786 0.692 NM_002401
NM_203351
MAP3K3

mitogen-activated protein kinase kinase kinase 3

chr1_+_162467594 0.692 NM_144624
NM_175866
UHMK1

U2AF homology motif (UHM) kinase 1

chr11_-_16424391 0.685 NM_001145819
NM_017508
SOX6

SRY (sex determining region Y)-box 6

chr2_-_198175494 0.684 NM_001195144
NM_153697
ANKRD44

ankyrin repeat domain 44

chr4_-_99579540 0.681 NM_005723
TSPAN5
tetraspanin 5
chr7_+_155250705 0.675 NM_001427
EN2
engrailed homeobox 2
chr15_-_65579017 0.666 NM_017851
PARP16
poly (ADP-ribose) polymerase family, member 16
chr7_-_55640198 0.662 NM_030796
VOPP1
vesicular, overexpressed in cancer, prosurvival protein 1
chr20_+_1093905 0.661 NM_178578
PSMF1
proteasome (prosome, macropain) inhibitor subunit 1 (PI31)
chr7_-_121944485 0.661 NM_001024613
NM_001160264
FEZF1

FEZ family zinc finger 1

chr5_+_5422792 0.654 NM_015325
KIAA0947
KIAA0947
chr1_+_36348795 0.654 NM_012199
EIF2C1
eukaryotic translation initiation factor 2C, 1
chr18_-_3011944 0.644 NM_014646
LPIN2
lipin 2
chr16_-_70472920 0.643 NM_006927
ST3GAL2
ST3 beta-galactoside alpha-2,3-sialyltransferase 2
chr2_-_46384 0.643 NM_001077710
FAM110C
family with sequence similarity 110, member C
chr1_+_26438267 0.642 NM_001243533
NM_152835
PDIK1L

PDLIM1 interacting kinase 1 like

chr3_-_122233781 0.637 NM_002264
KPNA1
karyopherin alpha 1 (importin alpha 5)
chr17_-_35969401 0.636 NM_001163544
NM_001163545
NM_001163546
NM_001163547
NM_007247
NM_080550
NM_198882
SYNRG






synergin, gamma






chr20_+_37434294 0.635 NM_001172735
NM_015568
PPP1R16B

protein phosphatase 1, regulatory subunit 16B


Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
1.67 3.20e-03 GO:0050789 regulation of biological process
3.73 8.40e-03 GO:0006793 phosphorus metabolic process
3.73 8.40e-03 GO:0006796 phosphate metabolic process
1.57 2.38e-02 GO:0065007 biological regulation
8.29 4.22e-02 GO:0002764 immune response-regulating signaling pathway
2.65 4.43e-02 GO:0006464 protein modification process

Nothing significant found in compartment category.

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
4.57 1.52e-04 GO:0016301 kinase activity
3.95 8.30e-04 GO:0016772 transferase activity, transferring phosphorus-containing groups
4.20 2.15e-03 GO:0016773 phosphotransferase activity, alcohol group as acceptor
4.58 2.24e-03 GO:0004672 protein kinase activity
5.20 5.08e-03 GO:0004674 protein serine/threonine kinase activity
2.71 6.24e-03 GO:0016740 transferase activity
2.72 1.70e-02 GO:0005524 ATP binding
2.68 2.03e-02 GO:0032559 adenyl ribonucleotide binding
2.66 2.16e-02 GO:0030554 adenyl nucleotide binding
2.25 3.00e-02 GO:0000166 nucleotide binding