Motif ID: GCUGGUG

Z-value: 1.384


Mature miRNA associated with seed GCUGGUG:

NamemiRBase Accession
hsa-miR-138 MIMAT0000430



Activity profile for motif GCUGGUG.

activity profile for motif GCUGGUG


Sorted Z-values histogram for motif GCUGGUG

Sorted Z-values for motif GCUGGUG



Network of associatons between targets according to the STRING database.



First level regulatory network of GCUGGUG

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr19_-_49944613 3.483 NM_020309
SLC17A7
solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7
chr8_-_41522724 3.180 NM_001142445
NM_020478
NM_020480
ANK1


ankyrin 1, erythrocytic


chr17_-_9929567 3.102 NM_001130831
GAS7
growth arrest-specific 7
chr7_+_31092067 2.742 NM_001118
NM_001199635
NM_001199636
NM_001199637
ADCYAP1R1



adenylate cyclase activating polypeptide 1 (pituitary) receptor type I



chr14_+_52327021 2.604 NM_001243773
NM_001243774
NM_053064
GNG2


guanine nucleotide binding protein (G protein), gamma 2


chrX_-_102531673 2.588 NM_001012979
TCEAL5
transcription elongation factor A (SII)-like 5
chr17_-_9940004 2.539 NM_201432
GAS7
growth arrest-specific 7
chr4_+_159131400 2.484 NM_018342
TMEM144
transmembrane protein 144
chr8_-_41655139 2.445 NM_000037
NM_020475
NM_020476
NM_020477
ANK1



ankyrin 1, erythrocytic



chr5_-_176057324 2.407 NM_001001502
NM_003085
SNCB

synuclein, beta

chr17_-_10101854 2.378 NM_201433
GAS7
growth arrest-specific 7
chr5_+_139175385 2.273 NM_032289
PSD2
pleckstrin and Sec7 domain containing 2
chr17_-_9862765 2.224 NM_003644
GAS7
growth arrest-specific 7
chr2_-_73496595 2.222 NM_001080410
FBXO41
F-box protein 41
chr2_-_101034049 2.132 NM_004854
CHST10
carbohydrate sulfotransferase 10
chr15_+_52043738 1.982 NM_001142885
NM_014548
TMOD2

tropomodulin 2 (neuronal)

chr12_-_54785018 1.970 NM_001130967
NM_001130968
ZNF385A

zinc finger protein 385A

chr7_-_30029904 1.923 NM_001145514
SCRN1
secernin 1
chr1_-_149889362 1.922 NM_014849
SV2A
synaptic vesicle glycoprotein 2A
chr6_+_158733691 1.911 NM_001007466
NM_020245
TULP4

tubby like protein 4

chrX_-_25034064 1.910 NM_139058
ARX
aristaless related homeobox
chr11_-_57417247 1.906 NM_145008
YPEL4
yippee-like 4 (Drosophila)
chr12_-_54778456 1.875 NM_015481
ZNF385A
zinc finger protein 385A
chr19_-_14316980 1.845 NM_001008701
NM_014921
LPHN1

latrophilin 1

chr12_+_128751947 1.818 NM_001136103
TMEM132C
transmembrane protein 132C
chr11_-_78052925 1.787 NM_012296
GAB2
GRB2-associated binding protein 2
chr2_+_7057471 1.764 NM_014746
RNF144A
ring finger protein 144A
chr7_-_30029284 1.725 NM_001145515
NM_014766
NM_001145513
SCRN1


secernin 1


chr2_+_220299699 1.709 NM_005876
SPEG
SPEG complex locus
chr19_+_3880617 1.615 NM_033064
ATCAY
ataxia, cerebellar, Cayman type
chr17_-_78450247 1.605 NM_002522
NPTX1
neuronal pentraxin I
chr7_+_73507485 1.595 NM_001204426
LIMK1
LIM domain kinase 1
chr7_-_128001657 1.586 NM_001114726
NM_001174164
PRRT4

proline-rich transmembrane protein 4

chr8_+_104831415 1.561 NM_014677
RIMS2
regulating synaptic membrane exocytosis 2
chr1_+_40862471 1.558 NM_001198980
SMAP2
small ArfGAP2
chr20_+_10199455 1.545 NM_003081
NM_130811
SNAP25

synaptosomal-associated protein, 25kDa

chr20_-_35488275 1.534 NM_199181
KIAA0889
KIAA0889
chr9_-_127905715 1.511 NM_001144877
NM_173690
SCAI

suppressor of cancer cell invasion

chr6_+_118228688 1.509 NM_001029858
SLC35F1
solute carrier family 35, member F1
chr2_-_100758970 1.455 NM_002285
AFF3
AF4/FMR2 family, member 3
chr10_-_88126201 1.443 NM_017551
GRID1
glutamate receptor, ionotropic, delta 1
chr13_+_30002776 1.429 NM_015233
MTUS2
microtubule associated tumor suppressor candidate 2
chr7_+_73498106 1.426 NM_002314
LIMK1
LIM domain kinase 1
chr3_-_13008959 1.423 NM_014869
IQSEC1
IQ motif and Sec7 domain 1
chr13_+_29598746 1.391 NM_001033602
MTUS2
microtubule associated tumor suppressor candidate 2
chr2_-_145277879 1.377 NM_001171653
NM_014795
ZEB2

zinc finger E-box binding homeobox 2

chr11_+_131240370 1.367 NM_001048209
NTM
neurotrimin
chr11_-_123525300 1.359 NM_001040151
NM_018400
SCN3B

sodium channel, voltage-gated, type III, beta

chrX_-_24665454 1.355 NM_001163265
NM_004845
PCYT1B

phosphate cytidylyltransferase 1, choline, beta

chr18_-_70534809 1.346 NM_001201465
NM_138966
NETO1

neuropilin (NRP) and tolloid (TLL)-like 1

chr1_-_32403975 1.314 NM_080391
PTP4A2
protein tyrosine phosphatase type IVA, member 2
chrX_-_24690740 1.308 NM_001163264
PCYT1B
phosphate cytidylyltransferase 1, choline, beta
chr3_+_23987514 1.303 NM_001145425
NR1D2
nuclear receptor subfamily 1, group D, member 2
chr1_-_32385258 1.282 NM_001195100
NM_001195101
PTP4A2

protein tyrosine phosphatase type IVA, member 2

chr3_-_9291251 1.278 NM_001033117
NM_014850
SRGAP3

SLIT-ROBO Rho GTPase activating protein 3

chr20_-_3149070 1.274 NM_014731
ProSAPiP1
ProSAPiP1 protein
chr3_-_13114547 1.220 NM_001134382
IQSEC1
IQ motif and Sec7 domain 1
chr10_+_71075609 1.216 NM_033496
HK1
hexokinase 1
chr11_-_129062092 1.197 NM_001142685
ARHGAP32
Rho GTPase activating protein 32
chr11_-_128894008 1.196 NM_014715
ARHGAP32
Rho GTPase activating protein 32
chr11_-_78128852 1.188 NM_080491
GAB2
GRB2-associated binding protein 2
chr3_+_23986735 1.185 NM_005126
NR1D2
nuclear receptor subfamily 1, group D, member 2
chr20_+_17206751 1.167 NM_001201528
PCSK2
proprotein convertase subtilisin/kexin type 2
chr8_+_104512975 1.163 NM_001100117
RIMS2
regulating synaptic membrane exocytosis 2
chr14_-_65289812 1.155 NM_000347
NM_001024858
SPTB

spectrin, beta, erythrocytic

chr1_+_40840304 1.151 NM_001198978
SMAP2
small ArfGAP2
chr11_-_75062650 1.141 NM_004041
NM_020251
ARRB1

arrestin, beta 1

chr17_+_74868728 1.137 NM_198955
MGAT5B
mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase, isozyme B
chr20_-_43438881 1.133 NM_001205317
NM_182970
RIMS4

regulating synaptic membrane exocytosis 4

chr20_-_4795768 1.130 NM_170774
RASSF2
Ras association (RalGDS/AF-6) domain family member 2
chr5_+_176237435 1.115 NM_133369
UNC5A
unc-5 homolog A (C. elegans)
chr17_+_30593194 1.103 NM_138328
RHBDL3
rhomboid, veinlet-like 3 (Drosophila)
chr3_-_57113292 1.097 NM_001128615
ARHGEF3
Rho guanine nucleotide exchange factor (GEF) 3
chr20_-_4804067 1.093 NM_014737
RASSF2
Ras association (RalGDS/AF-6) domain family member 2
chr3_-_56835829 1.085 NM_019555
ARHGEF3
Rho guanine nucleotide exchange factor (GEF) 3
chr10_+_71029755 1.082 NM_033497
NM_033498
NM_033500
HK1


hexokinase 1


chr3_-_39321479 1.073 NM_001337
CX3CR1
chemokine (C-X3-C motif) receptor 1
chr19_+_51815095 1.073 NM_001101372
IGLON5
IgLON family member 5
chr1_+_40859016 1.068 NM_001198979
SMAP2
small ArfGAP2
chr11_+_66234293 1.061 NM_001098510
NM_001243136
NM_145065
PELI3


pellino homolog 3 (Drosophila)


chr12_+_119419299 1.059 NM_194286
SRRM4
serine/arginine repetitive matrix 4
chr10_+_17270257 1.054 NM_003380
VIM
vimentin
chr1_-_173176314 1.050 NM_003326
TNFSF4
tumor necrosis factor (ligand) superfamily, member 4
chr17_+_38465422 1.049 NM_000964
RARA
retinoic acid receptor, alpha
chr4_-_165304406 1.043 NM_001166373
MARCH1
membrane-associated ring finger (C3HC4) 1
chr22_-_44893903 1.040 NM_032287
LDOC1L
leucine zipper, down-regulated in cancer 1-like
chr20_-_35492069 1.038 NM_080627
KIAA0889
KIAA0889
chr14_+_72398816 1.020 NM_001204423
RGS6
regulator of G-protein signaling 6
chrX_+_69674914 1.006 NM_001166278
DLG3
discs, large homolog 3 (Drosophila)
chr10_+_71078575 1.005 NM_000188
HK1
hexokinase 1
chr3_-_39323183 0.995 NM_001171174
CX3CR1
chemokine (C-X3-C motif) receptor 1
chr22_-_45636584 0.987 NM_001009880
KIAA0930
KIAA0930
chr1_+_203020310 0.984 NM_015053
PPFIA4
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4
chr3_-_56809594 0.984 NM_001128616
ARHGEF3
Rho guanine nucleotide exchange factor (GEF) 3
chr6_-_46293628 0.973 NM_005822
RCAN2
regulator of calcineurin 2
chr2_-_100721792 0.971 NM_001025108
AFF3
AF4/FMR2 family, member 3
chr8_-_41754244 0.970 NM_001142446
ANK1
ankyrin 1, erythrocytic
chrX_+_102862833 0.969 NM_001006933
NM_032926
TCEAL3

transcription elongation factor A (SII)-like 3

chr19_+_13105970 0.968 NM_002501
NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr17_-_58603492 0.962 NM_006380
APPBP2
amyloid beta precursor protein (cytoplasmic tail) binding protein 2
chr13_+_42846255 0.960 NM_016248
AKAP11
A kinase (PRKA) anchor protein 11
chr5_-_148442606 0.953 NM_024577
SH3TC2
SH3 domain and tetratricopeptide repeats 2
chr2_+_113033146 0.947 NM_198581
ZC3H6
zinc finger CCCH-type containing 6
chr15_+_49170264 0.945 NM_014335
EID1
EP300 interacting inhibitor of differentiation 1
chr15_-_75748123 0.938 NM_001145357
SIN3A
SIN3 transcription regulator homolog A (yeast)
chr4_-_164534656 0.933 NM_017923
MARCH1
membrane-associated ring finger (C3HC4) 1
chr14_+_72399149 0.932 NM_001204424
RGS6
regulator of G-protein signaling 6
chr1_-_41131323 0.932 NM_014747
RIMS3
regulating synaptic membrane exocytosis 3
chr10_+_129845806 0.931 NM_130435
PTPRE
protein tyrosine phosphatase, receptor type, E
chr4_-_42658883 0.931 NM_001105529
NM_006095
ATP8A1

ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1

chr22_-_45608346 0.923 NM_015264
KIAA0930
KIAA0930
chr9_+_34958171 0.910 NM_015297
KIAA1045
KIAA1045
chr15_-_48470453 0.901 NM_016132
MYEF2
myelin expression factor 2
chr17_-_27916602 0.900 NM_001085454
NM_014030
GIT1

G protein-coupled receptor kinase interacting ArfGAP 1

chr17_+_7743233 0.898 NM_001080424
KDM6B
lysine (K)-specific demethylase 6B
chr16_+_1031807 0.896 NM_014587
SOX8
SRY (sex determining region Y)-box 8
chr8_-_53626991 0.896 NM_001083617
NM_014781
RB1CC1

RB1-inducible coiled-coil 1

chr9_+_17578952 0.880 NM_003026
SH3GL2
SH3-domain GRB2-like 2
chr3_-_39321929 0.868 NM_001171172
CX3CR1
chemokine (C-X3-C motif) receptor 1
chr11_-_85338313 0.867 NM_001142699
DLG2
discs, large homolog 2 (Drosophila)
chrX_-_101397370 0.865 NM_001006938
TCEAL6
transcription elongation factor A (SII)-like 6
chr3_-_39322763 0.857 NM_001171171
CX3CR1
chemokine (C-X3-C motif) receptor 1
chr17_-_73775822 0.857 NM_005324
H3F3B
H3 histone, family 3B (H3.3B)
chr2_-_235405692 0.855 NM_005737
ARL4C
ADP-ribosylation factor-like 4C
chr3_+_42695175 0.850 NM_145166
ZBTB47
zinc finger and BTB domain containing 47
chr8_+_106331146 0.848 NM_012082
ZFPM2
zinc finger protein, multitype 2
chr7_-_132261268 0.846 NM_001105543
NM_020911
PLXNA4

plexin A4

chr14_+_60712469 0.823 NM_177952
PPM1A
protein phosphatase, Mg2+/Mn2+ dependent, 1A
chr9_-_131534186 0.811 NM_006336
ZER1
zer-1 homolog (C. elegans)
chr17_+_27920479 0.805 NM_152345
ANKRD13B
ankyrin repeat domain 13B
chr1_+_40839368 0.790 NM_022733
SMAP2
small ArfGAP2
chr20_+_44650260 0.790 NM_001134771
SLC12A5
solute carrier family 12 (potassium/chloride transporter), member 5
chr6_-_31628509 0.786 NM_021184
C6orf47
chromosome 6 open reading frame 47
chr7_-_28220342 0.785 NM_175061
JAZF1
JAZF zinc finger 1
chr11_+_131780537 0.775 NM_001144058
NM_001144059
NM_016522
NTM


neurotrimin


chr3_+_138067444 0.766 NM_001085049
NM_001252093
MRAS

muscle RAS oncogene homolog

chr3_+_138066489 0.760 NM_001252091
NM_012219
MRAS

muscle RAS oncogene homolog

chr12_-_46663207 0.748 NM_001077484
NM_030674
SLC38A1

solute carrier family 38, member 1

chr15_-_64338519 0.737 NM_014326
DAPK2
death-associated protein kinase 2
chr10_+_129705299 0.737 NM_006504
PTPRE
protein tyrosine phosphatase, receptor type, E
chr1_-_162381805 0.734 NM_053282
SH2D1B
SH2 domain containing 1B
chr15_-_75744029 0.718 NM_001145358
SIN3A
SIN3 transcription regulator homolog A (yeast)
chr7_-_72936592 0.704 NM_032408
BAZ1B
bromodomain adjacent to zinc finger domain, 1B
chrX_+_69672110 0.702 NM_020730
DLG3
discs, large homolog 3 (Drosophila)
chr6_+_34759743 0.699 NM_017754
UHRF1BP1
UHRF1 binding protein 1
chr7_-_149194896 0.694 NM_001163474
NM_152557
ZNF746

zinc finger protein 746

chr4_+_113970784 0.692 NM_001148
NM_020977
ANK2

ankyrin 2, neuronal

chr13_+_35516390 0.687 NM_015678
NBEA
neurobeachin
chr5_-_142815076 0.664 NM_001018074
NM_001018075
NM_001018077
NR3C1


nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)


chr11_-_83393436 0.653 NM_001142702
DLG2
discs, large homolog 2 (Drosophila)
chr2_-_240322620 0.651 NM_006037
HDAC4
histone deacetylase 4
chr3_+_140660639 0.647 NM_001104647
NM_018155
SLC25A36

solute carrier family 25, member 36

chr20_-_36152952 0.645 NM_001167823
BLCAP
bladder cancer associated protein
chr14_+_71374111 0.642 NM_014982
PCNX
pecanex homolog (Drosophila)
chr5_-_74162614 0.635 NM_015566
FAM169A
family with sequence similarity 169, member A
chr3_-_161089747 0.635 NM_001040100
SPTSSB
serine palmitoyltransferase, small subunit B
chr22_+_39101806 0.630 NM_004286
GTPBP1
GTP binding protein 1
chr6_+_39760772 0.627 NM_015345
DAAM2
dishevelled associated activator of morphogenesis 2
chr2_-_60780404 0.625 NM_018014
NM_022893
NM_138559
BCL11A


B-cell CLL/lymphoma 11A (zinc finger protein)


chrX_+_152599544 0.619 NM_001080485
ZNF275
zinc finger protein 275
chr7_+_129015483 0.619 NM_001130722
AHCYL2
adenosylhomocysteinase-like 2
chr2_+_135809834 0.617 NM_001172435
NM_012233
RAB3GAP1

RAB3 GTPase activating protein subunit 1 (catalytic)

chr19_+_3224700 0.609 NM_021938
NM_001172673
CELF5

CUGBP, Elav-like family member 5

chr12_+_132195632 0.604 NM_004592
SFSWAP
splicing factor, suppressor of white-apricot homolog (Drosophila)
chr8_+_26240522 0.603 NM_004331
BNIP3L
BCL2/adenovirus E1B 19kDa interacting protein 3-like
chr1_+_33116748 0.601 NM_001135255
NM_005610
NM_001135256
RBBP4


retinoblastoma binding protein 4


chr17_-_4890920 0.600 NM_001171166
NM_015099
CAMTA2

calmodulin binding transcription activator 2

chr6_+_87865261 0.599 NM_015021
ZNF292
zinc finger protein 292
chr2_+_28615771 0.598 NM_005253
FOSL2
FOS-like antigen 2
chr15_-_51914770 0.596 NM_001174116
NM_001174117
NM_015263
DMXL2


Dmx-like 2


chr11_+_63655986 0.596 NM_017490
MARK2
MAP/microtubule affinity-regulating kinase 2
chr14_+_72399785 0.590 NM_001204416
NM_001204417
NM_001204418
NM_001204419
NM_001204420
NM_001204421
NM_001204422
NM_004296
RGS6







regulator of G-protein signaling 6







chr1_-_109935869 0.587 NM_001205228
SORT1
sortilin 1
chrX_+_69664704 0.584 NM_021120
DLG3
discs, large homolog 3 (Drosophila)
chr2_+_109223600 0.575 NM_001193482
LIMS1
LIM and senescent cell antigen-like domains 1
chr19_-_55954229 0.575 NM_001145176
SHISA7
shisa homolog 7 (Xenopus laevis)
chrX_+_152954965 0.575 NM_001142806
SLC6A8
solute carrier family 6 (neurotransmitter transporter, creatine), member 8
chr17_+_42836546 0.573 NM_002390
ADAM11
ADAM metallopeptidase domain 11
chr6_+_15246299 0.566 NM_004973
JARID2
jumonji, AT rich interactive domain 2
chr2_-_182545212 0.566 NM_002500
CERKL
NEUROD1
ceramide kinase-like
neurogenic differentiation 1
chr22_+_35653444 0.561 NM_001003681
HMGXB4
HMG box domain containing 4
chr20_+_17207596 0.561 NM_001201529
NM_002594
PCSK2

proprotein convertase subtilisin/kexin type 2

chr20_-_4990913 0.561 NM_203327
SLC23A2
solute carrier family 23 (nucleobase transporters), member 2
chr1_-_31712733 0.552 NM_024522
NKAIN1
Na+/K+ transporting ATPase interacting 1
chr11_-_84028379 0.552 NM_001206769
DLG2
discs, large homolog 2 (Drosophila)
chr9_-_36400212 0.550 NM_022781
NM_194329
RNF38

ring finger protein 38

chr22_-_39240016 0.540 NM_014293
NPTXR
neuronal pentraxin receptor
chr19_+_45909466 0.538 NM_012099
CD3EAP
CD3e molecule, epsilon associated protein
chr10_-_73533196 0.537 NM_022153
C10orf54
chromosome 10 open reading frame 54
chr5_-_114880536 0.529 NM_020177
FEM1C
fem-1 homolog c (C. elegans)
chr1_-_211307314 0.528 NM_002238
NM_172362
KCNH1

potassium voltage-gated channel, subfamily H (eag-related), member 1

chr21_-_28339405 0.525 NM_007038
ADAMTS5
ADAM metallopeptidase with thrombospondin type 1 motif, 5
chr15_-_43877043 0.521 NM_014659
PPIP5K1
diphosphoinositol pentakisphosphate kinase 1
chr3_+_69134057 0.514 NM_006407
ARL6IP5
ADP-ribosylation-like factor 6 interacting protein 5
chr11_-_77348758 0.512 NM_001293
CLNS1A
chloride channel, nucleotide-sensitive, 1A
chr18_-_53255734 0.512 NM_001083962
NM_001243230
NM_003199
TCF4


transcription factor 4


chr17_+_38474472 0.511 NM_001145301
NM_001145302
RARA

retinoic acid receptor, alpha

chr17_-_8301143 0.508 NM_001146684
RNF222
ring finger protein 222
chr5_+_150632612 0.507 NM_000405
NM_001167607
GM2A

GM2 ganglioside activator

chr10_+_125425870 0.507 NM_153442
GPR26
G protein-coupled receptor 26

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
3.35 2.20e-03 GO:0007399 nervous system development

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
7.38 2.25e-05 GO:0045202 synapse
8.13 1.42e-04 GO:0044456 synapse part
5.06 9.02e-04 GO:0030054 cell junction
5.44 1.03e-02 GO:0043005 neuron projection
103.94 1.47e-02 GO:0014731 spectrin-associated cytoskeleton
103.94 1.47e-02 GO:0060076 excitatory synapse
13.17 2.41e-02 GO:0014069 postsynaptic density
13.01 2.53e-02 GO:0009898 internal side of plasma membrane
22.94 3.00e-02 GO:0005834 heterotrimeric G-protein complex
2.31 4.63e-02 GO:0044459 plasma membrane part

Nothing significant found in function category.