• All motifs sorted by activity significance
• All samples sorted alphabetically
• Mean activities

• Activities table
• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)
• Download the whole report

Motif ID: GTF2I.p2

Z-value: 2.780

---

Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chrX_+_144899330	11.452	NM_001144003 NM_001144004 NM_001144005 NM_032539	SLITRK2	SLIT and NTRK-like family, member 2
chr19_-_51071279	9.196	NM_001080457	LRRC4B	leucine rich repeat containing 4B
chr19_-_49149252	8.829	NM_001217	CA11	carbonic anhydrase XI
chr2_+_79740059	7.499	NM_001164883 NM_004389	CTNNA2	catenin (cadherin-associated protein), alpha 2
chr19_-_51487070	7.176	NM_139277 NM_001207053 NM_001243126 NM_005046	KLK7	kallikrein-related peptidase 7
chr17_+_37783202	6.978		PPP1R1B	protein phosphatase 1, regulatory (inhibitor) subunit 1B
chr19_-_47975074	6.773		SLC8A2	solute carrier family 8 (sodium/calcium exchanger), member 2
chr17_-_7120917	6.601	NM_001128827	DLG4	discs, large homolog 4 (Drosophila)
chr20_+_43374487	6.461	NM_022358	KCNK15	potassium channel, subfamily K, member 15
chr17_+_37783176	6.459	NM_032192	PPP1R1B	protein phosphatase 1, regulatory (inhibitor) subunit 1B
chr4_-_5889992	6.031		CRMP1	collapsin response mediator protein 1
chr6_+_1390068	6.027	NM_001452	FOXF2	forkhead box F2
chr16_-_65155881	5.989	NM_001797	CDH11	cadherin 11, type 2, OB-cadherin (osteoblast)
chr14_-_24047993	5.925	NM_001146028 NM_032452	JPH4	junctophilin 4
chr4_-_16900028	5.816		LDB2	LIM domain binding 2
chr20_-_55841090	5.564		BMP7	bone morphogenetic protein 7
chr15_-_37392358	5.420	NM_170674 NM_170675 NM_170676 NM_170677	MEIS2	Meis homeobox 2
chr11_-_62688732	5.370		CHRM1	cholinergic receptor, muscarinic 1
chr4_-_5890142	5.313		CRMP1	collapsin response mediator protein 1
chr1_+_203444882	5.279	NM_002725 NM_201348	PRELP	proline/arginine-rich end leucine-rich repeat protein
chr11_+_125034604	5.176		PKNOX2	PBX/knotted 1 homeobox 2
chr16_-_65155965	5.024		CDH11	cadherin 11, type 2, OB-cadherin (osteoblast)
chr2_-_241759627	4.990	NM_001244008 NM_004321	KIF1A	kinesin family member 1A
chr7_+_128431449	4.949	NM_001201372	CCDC136	coiled-coil domain containing 136
chr12_+_49209300	4.923	NM_001206916	CACNB3	calcium channel, voltage-dependent, beta 3 subunit
chr6_-_29600668	4.904		GABBR1	gamma-aminobutyric acid (GABA) B receptor, 1
chr11_-_62689011	4.876	NM_000738	CHRM1	cholinergic receptor, muscarinic 1
chr19_+_55795766	4.810		BRSK1	BR serine/threonine kinase 1
chr5_+_175298492	4.763	NM_001008220	CPLX2	complexin 2
chr8_+_104512975	4.692	NM_001100117	RIMS2	regulating synaptic membrane exocytosis 2
chr1_-_20812727	4.602	NM_018584	CAMK2N1	calcium/calmodulin-dependent protein kinase II inhibitor 1
chr13_-_36705432	4.598		DCLK1	doublecortin-like kinase 1
chr14_-_24047774	4.579		JPH4	junctophilin 4
chr11_+_125034558	4.484	NM_022062	PKNOX2	PBX/knotted 1 homeobox 2
chr17_+_64960754	4.454	NM_014405	CACNG4	calcium channel, voltage-dependent, gamma subunit 4
chr3_+_77089248	4.396	NM_002942	ROBO2	roundabout, axon guidance receptor, homolog 2 (Drosophila)
chr16_-_65155984	4.393		CDH11	cadherin 11, type 2, OB-cadherin (osteoblast)
chr5_+_175298604	4.386		CPLX2	complexin 2
chr5_-_146833150	4.372	NM_001387	DPYSL3	dihydropyrimidinase-like 3
chr19_-_47975244	4.321	NM_015063	SLC8A2	solute carrier family 8 (sodium/calcium exchanger), member 2
chr8_-_26371387	4.320	NM_007257	PNMA2	paraneoplastic antigen MA2
chrX_-_119445306	4.271	NM_001104544 NM_001104545 NM_017938	FAM70A	family with sequence similarity 70, member A
chr1_-_72748147	4.232	NM_173808	NEGR1	neuronal growth regulator 1
chr4_-_16900256	4.226		LDB2	LIM domain binding 2
chr3_-_42307661	4.210	NM_000729	CCK	cholecystokinin
chr19_-_51472003	4.208	NM_001012964 NM_001012965	KLK6	kallikrein-related peptidase 6
chr2_+_79740171	4.144		CTNNA2	catenin (cadherin-associated protein), alpha 2
chr8_-_22549901	4.124	NM_001199880	EGR3	early growth response 3
chr15_-_51386815	4.103		TNFAIP8L3	tumor necrosis factor, alpha-induced protein 8-like 3
chr19_-_291335	4.078	NM_003712 NM_177526	PPAP2C	phosphatidic acid phosphatase type 2C
chr1_+_157963310	4.018		KIRREL	kin of IRRE like (Drosophila)
chr12_+_58005217	3.991	NM_182947	ARHGEF25	Rho guanine nucleotide exchange factor (GEF) 25
chr13_+_58205943	3.957		PCDH17	protocadherin 17
chr14_+_24837225	3.947	NM_001198965 NM_004554	NFATC4	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
chr19_+_3224734	3.945		CELF5	CUGBP, Elav-like family member 5
chr19_+_55999921	3.942		SSC5D	scavenger receptor cysteine rich domain containing (5 domains)
chr13_-_96296919	3.936	NM_014934 NM_198968	DZIP1	DAZ interacting protein 1
chr4_-_16900348	3.907	NM_001130834 NM_001290	LDB2	LIM domain binding 2
chr11_-_123065836	3.886		CLMP	CXADR-like membrane protein
chr1_+_159141376	3.843	NM_021189 NM_001127173	CADM3	cell adhesion molecule 3
chr11_+_17757494	3.829	NM_001112741 NM_004976	KCNC1	potassium voltage-gated channel, Shaw-related subfamily, member 1
chr22_+_45898690	3.827	NM_001996 NM_006485 NM_006486 NM_006487	FBLN1	fibulin 1
chr9_+_133971902	3.803		AIF1L	allograft inflammatory factor 1-like
chr13_+_58205788	3.797	NM_001040429	PCDH17	protocadherin 17
chr15_+_43809805	3.788	NM_002373	MAP1A	microtubule-associated protein 1A
chr15_-_88799961	3.784	NM_001007156 NM_001012338 NM_001243101 NM_002530	NTRK3	neurotrophic tyrosine kinase, receptor, type 3
chr5_+_92920592	3.779		NR2F1 NR2F2	nuclear receptor subfamily 2, group F, member 1 nuclear receptor subfamily 2, group F, member 2
chrX_-_119445279	3.728		FAM70A	family with sequence similarity 70, member A
chr12_-_16759939	3.717	NM_001243613	LMO3	LIM domain only 3 (rhombotin-like 2)
chr17_+_7311501	3.695	NM_020795	NLGN2	neuroligin 2
chr19_-_54984341	3.679	NM_145057	CDC42EP5	CDC42 effector protein (Rho GTPase binding) 5
chr8_+_27491460	3.673	NM_016240 NM_182826	SCARA3	scavenger receptor class A, member 3
chr17_-_37381920	3.665	NM_198993	STAC2	SH3 and cysteine rich domain 2
chr19_+_3224700	3.627	NM_021938 NM_001172673	CELF5	CUGBP, Elav-like family member 5
chr3_-_161089747	3.564	NM_001040100	SPTSSB	serine palmitoyltransferase, small subunit B
chr4_-_105416050	3.502		CXXC4	CXXC finger protein 4
chr19_-_11591439	3.497	NM_001420 NM_032281	ELAVL3	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C)
chr4_+_30721865	3.487	NM_032456 NM_001173523 NM_002589 NM_032457	PCDH7	protocadherin 7
chr1_-_72748491	3.484
chr12_+_49208214	3.476	NM_001206917	CACNB3	calcium channel, voltage-dependent, beta 3 subunit
chr4_-_168155732	3.474	NM_001040159 NM_001204352 NM_001204354 NM_001204355 NM_001204356 NM_001204358 NM_001251967 NM_016950	SPOCK3	sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
chr1_-_20812271	3.466		CAMK2N1	calcium/calmodulin-dependent protein kinase II inhibitor 1
chr19_+_55795533	3.453	NM_032430	BRSK1	BR serine/threonine kinase 1
chr7_+_103969103	3.443	NM_199000	LHFPL3	lipoma HMGIC fusion partner-like 3
chr1_-_177133818	3.370		ASTN1	astrotactin 1
chr4_-_168155691	3.358		SPOCK3	sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
chr16_-_29910340	3.348	NM_001114099 NM_001114100 NM_001243332 NM_001243333 NM_012410 NM_201575	SEZ6L2	seizure related 6 homolog (mouse)-like 2
chr19_+_55999859	3.334	NM_001144950 NM_001195267	SSC5D	scavenger receptor cysteine rich domain containing (5 domains)
chr22_-_38380538	3.331	NM_006941	SOX10	SRY (sex determining region Y)-box 10
chr9_+_130374466	3.323	NM_001032221 NM_003165	STXBP1	syntaxin binding protein 1
chr19_-_51472816	3.268	NM_002774	KLK6	kallikrein-related peptidase 6
chr13_-_36705513	3.236	NM_004734	DCLK1	doublecortin-like kinase 1
chr18_-_35145603	3.216		CELF4	CUGBP, Elav-like family member 4
chr7_-_32110979	3.172	NM_001191059 NM_005020	PDE1C	phosphodiesterase 1C, calmodulin-dependent 70kDa
chr6_-_29600959	3.162	NM_001470 NM_021904	GABBR1	gamma-aminobutyric acid (GABA) B receptor, 1
chr12_-_16759733	3.157	NM_001243610	LMO3	LIM domain only 3 (rhombotin-like 2)
chr2_+_220492286	3.109	NM_005070 NM_201574	SLC4A3	solute carrier family 4, anion exchanger, member 3
chr14_-_54423448	3.103	NM_001202 NM_130850	BMP4	bone morphogenetic protein 4
chr9_+_8858130	3.080
chr6_-_29600859	3.074		GABBR1	gamma-aminobutyric acid (GABA) B receptor, 1
chr7_+_30951414	3.072	NM_198098	AQP1	aquaporin 1 (Colton blood group)
chr19_+_35782988	3.071	NM_001199216 NM_002361 NM_080600	MAG	myelin associated glycoprotein
chr14_+_33408458	3.067	NM_001164749 NM_001165893 NM_022123 NM_173159	NPAS3	neuronal PAS domain protein 3
chr9_+_133971862	3.057	NM_001185095 NM_001185096 NM_031426	AIF1L	allograft inflammatory factor 1-like
chr8_-_144241918	3.009	NM_001130478	LY6H	lymphocyte antigen 6 complex, locus H
chr19_+_54926604	2.991	NM_001005367 NM_001201461 NM_020659	TTYH1	tweety homolog 1 (Drosophila)
chr8_-_33457435	2.970	NM_024025	DUSP26	dual specificity phosphatase 26 (putative)
chr12_-_50297575	2.964	NM_012306	FAIM2	Fas apoptotic inhibitory molecule 2
chr1_+_210406194	2.951	NM_019605	SERTAD4	SERTA domain containing 4
chrX_+_103031753	2.943	NM_000533 NM_199478	PLP1	proteolipid protein 1
chr4_-_121993568	2.932	NM_024574	NDNF	neuron-derived neurotrophic factor
chr5_+_175223519	2.907	NM_006650	CPLX2	complexin 2
chr1_+_160051343	2.885	NM_004983	KCNJ9	potassium inwardly-rectifying channel, subfamily J, member 9
chr5_+_71403040	2.884	NM_005909	MAP1B	microtubule-associated protein 1B
chr8_-_89339716	2.883	NM_005941	MMP16	matrix metallopeptidase 16 (membrane-inserted)
chr19_-_291168	2.877	NM_177543	PPAP2C	phosphatidic acid phosphatase type 2C
chr16_-_10276610	2.873	NM_000833	GRIN2A	glutamate receptor, ionotropic, N-methyl D-aspartate 2A
chr2_+_220325533	2.870	NM_001173476	SPEG	SPEG complex locus
chr13_+_88324777	2.853	NM_015567	SLITRK5	SLIT and NTRK-like family, member 5
chr8_-_22550057	2.852	NM_001199881	EGR3	early growth response 3
chr14_-_27066959	2.835	NM_002515 NM_006489 NM_006491	NOVA1	neuro-oncological ventral antigen 1
chr11_-_57417247	2.818	NM_145008	YPEL4	yippee-like 4 (Drosophila)
chr4_-_168155576	2.814	NM_001204353	SPOCK3	sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
chr8_-_22550456	2.791		EGR3	early growth response 3
chr3_-_64673663	2.777		ADAMTS9	ADAM metallopeptidase with thrombospondin type 1 motif, 9
chr4_-_46391771	2.776	NM_000807	GABRA2	gamma-aminobutyric acid (GABA) A receptor, alpha 2
chrX_-_49056638	2.765	NM_003179	SYP	synaptophysin
chr2_-_193059249	2.743		TMEFF2	transmembrane protein with EGF-like and two follistatin-like domains 2
chr16_-_30042123	2.742	NM_031478	FAM57B	family with sequence similarity 57, member B
chr19_-_35633354	2.726		LGI4	leucine-rich repeat LGI family, member 4
chr9_+_139221931	2.693	NM_001145638 NM_015597	GPSM1	G-protein signaling modulator 1
chr5_+_92918924	2.692	NM_005654	NR2F1	nuclear receptor subfamily 2, group F, member 1
chr5_+_175298538	2.687		CPLX2	complexin 2
chr22_+_48972117	2.685	NM_015381	FAM19A5	family with sequence similarity 19 (chemokine (C-C motif)-like), member A5
chr16_+_29823557	2.672		PRRT2	proline-rich transmembrane protein 2
chr18_-_24129084	2.665	NM_001136205	KCTD1	potassium channel tetramerisation domain containing 1
chr17_+_19314490	2.659	NM_007148	RNF112	ring finger protein 112
chr4_-_5890266	2.643	NM_001313	CRMP1	collapsin response mediator protein 1
chr2_-_19558371	2.643	NM_145260	OSR1	odd-skipped related 1 (Drosophila)
chrX_+_107683015	2.641	NM_000495 NM_033380	COL4A5	collagen, type IV, alpha 5
chr11_-_40314510	2.639		LRRC4C	leucine rich repeat containing 4C
chr7_+_128432049	2.626	NM_022742	CCDC136	coiled-coil domain containing 136
chr15_-_27018160	2.620		GABRB3	gamma-aminobutyric acid (GABA) A receptor, beta 3
chrX_-_128788913	2.612	NM_017413	APLN	apelin
chr11_+_12399024	2.603	NM_018222	PARVA	parvin, alpha
chr19_-_49339913	2.600	NM_016246	HSD17B14	hydroxysteroid (17-beta) dehydrogenase 14
chr3_-_116164363	2.599	NM_002338	LSAMP	limbic system-associated membrane protein
chr7_+_86273867	2.598		GRM3	glutamate receptor, metabotropic 3
chr1_-_75139421	2.590	NM_001002912	C1orf173	chromosome 1 open reading frame 173
chr15_+_74466887	2.590	NM_201526	ISLR	immunoglobulin superfamily containing leucine-rich repeat
chrX_-_137793394	2.578		FGF13	fibroblast growth factor 13
chrX_-_137793826	2.570	NM_004114	FGF13	fibroblast growth factor 13
chr11_-_123065988	2.565	NM_024769	CLMP	CXADR-like membrane protein
chr19_-_49258646	2.555	NM_000148	FUT1	fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)
chr17_+_40913233	2.552		RAMP2	receptor (G protein-coupled) activity modifying protein 2
chr19_+_55888203	2.543	NM_139172	TMEM190	transmembrane protein 190
chr15_-_79298001	2.533	NM_153815	RASGRF1	Ras protein-specific guanine nucleotide-releasing factor 1
chr16_+_12995454	2.528	NM_001145204 NM_001145205	SHISA9	shisa homolog 9 (Xenopus laevis)
chr1_+_86046434	2.527	NM_001554	CYR61	cysteine-rich, angiogenic inducer, 61
chr12_-_45270071	2.522		NELL2	NEL-like 2 (chicken)
chr1_-_1475739	2.519	NM_001114748	TMEM240	transmembrane protein 240
chr1_+_203444955	2.499		PRELP	proline/arginine-rich end leucine-rich repeat protein
chrX_+_100474932	2.498	NM_001171184 NM_001939	DRP2	dystrophin related protein 2
chr2_+_26915390	2.482	NM_002246	KCNK3	potassium channel, subfamily K, member 3
chr20_-_62130390	2.482	NM_001958	EEF1A2	eukaryotic translation elongation factor 1 alpha 2
chr13_-_36705466	2.459		DCLK1	doublecortin-like kinase 1
chr10_-_88126201	2.450	NM_017551	GRID1	glutamate receptor, ionotropic, delta 1
chr19_+_49199227	2.443	NM_000511 NM_001097638	FUT2	fucosyltransferase 2 (secretor status included)
chr2_+_239756672	2.431	NM_057179	TWIST2	twist homolog 2 (Drosophila)
chr16_+_29823408	2.428	NM_145239	PRRT2	proline-rich transmembrane protein 2
chr6_+_17393610	2.416	NM_006366	CAP2	CAP, adenylate cyclase-associated protein, 2 (yeast)
chr7_+_73442486	2.415		ELN	elastin
chr3_+_167453431	2.402	NM_001122752 NM_005025	SERPINI1	serpin peptidase inhibitor, clade I (neuroserpin), member 1
chr15_-_74043815	2.401	NM_001039614	C15orf59	chromosome 15 open reading frame 59
chr9_+_77112251	2.364	NM_006914	RORB	RAR-related orphan receptor B
chr19_+_40973049	2.362	NM_020971	SPTBN4	spectrin, beta, non-erythrocytic 4
chr17_-_7122901	2.354		DLG4	discs, large homolog 4 (Drosophila)
chr2_-_169103886	2.352	NM_013233	STK39	serine threonine kinase 39
chr5_-_176900591	2.351		DBN1	drebrin 1
chr20_+_36531498	2.345	NM_080607	VSTM2L	V-set and transmembrane domain containing 2 like
chr18_-_45935627	2.340		ZBTB7C	zinc finger and BTB domain containing 7C
chr15_-_27018108	2.316		GABRB3	gamma-aminobutyric acid (GABA) A receptor, beta 3
chr2_-_193059599	2.315	NM_016192	TMEFF2	transmembrane protein with EGF-like and two follistatin-like domains 2
chr12_+_83081158	2.314		TMTC2	transmembrane and tetratricopeptide repeat containing 2
chrX_-_103087106	2.303	NM_016370	RAB9B	RAB9B, member RAS oncogene family
chr1_+_205538111	2.297	NM_181644	MFSD4	major facilitator superfamily domain containing 4
chr1_+_157963062	2.295	NM_018240	KIRREL	kin of IRRE like (Drosophila)
chr1_+_226736500	2.293	NM_001003665	C1orf95	chromosome 1 open reading frame 95
chr17_+_40834571	2.283	NM_003632	CNTNAP1	contactin associated protein 1
chr19_-_51523272	2.278	NM_002776 NM_001077500	KLK10	kallikrein-related peptidase 10
chr20_-_62103815	2.253	NM_004518 NM_172106 NM_172107 NM_172108 NM_172109	KCNQ2	potassium voltage-gated channel, KQT-like subfamily, member 2
chr7_-_150652861	2.248	NM_001204798 NM_172057	KCNH2	potassium voltage-gated channel, subfamily H (eag-related), member 2
chr1_+_110753910	2.245		KCNC4	potassium voltage-gated channel, Shaw-related subfamily, member 4
chr2_+_36582812	2.244		CRIM1	cysteine rich transmembrane BMP regulator 1 (chordin-like)
chr5_+_148786439	2.243		MIR143HG	MIR143 host gene (non-protein coding)
chr9_-_16870664	2.230		BNC2	basonuclin 2
chr11_-_68780667	2.229	NM_001098515 NM_145015	MRGPRF	MAS-related GPR, member F
chr14_+_24540742	2.218	NM_006032	CPNE6	copine VI (neuronal)
chr11_-_18813127	2.217	NM_001039970 NM_006906 NM_032781	PTPN5	protein tyrosine phosphatase, non-receptor type 5 (striatum-enriched)
chr11_-_118047336	2.202	NM_004588	SCN2B	sodium channel, voltage-gated, type II, beta

Gene overrepresentation in process category:

Enrichment	P-value	GO Accession	GO Term
3.20	2.58e-29	GO:0007399	nervous system development
2.26	3.54e-23	GO:0048731	system development
2.14	5.57e-22	GO:0048856	anatomical structure development
1.99	1.21e-21	GO:0032502	developmental process
2.06	1.97e-21	GO:0007275	multicellular organismal development
3.46	2.14e-20	GO:0022008	neurogenesis
1.75	3.10e-20	GO:0032501	multicellular organismal process
3.54	3.72e-20	GO:0048699	generation of neurons
3.64	7.29e-19	GO:0007267	cell-cell signaling
3.12	1.73e-17	GO:0007154	cell communication
3.59	1.72e-16	GO:0030182	neuron differentiation
4.37	8.82e-16	GO:0007268	synaptic transmission
4.05	5.57e-15	GO:0019226	transmission of nerve impulse
4.05	5.57e-15	GO:0035637	multicellular organismal signaling
2.24	1.12e-14	GO:0030154	cell differentiation
2.22	1.29e-14	GO:0048869	cellular developmental process
1.81	3.52e-14	GO:0023052	signaling
3.49	3.21e-12	GO:0048666	neuron development
2.38	4.14e-12	GO:0009653	anatomical structure morphogenesis
2.85	5.06e-12	GO:0048468	cell development
3.64	8.35e-12	GO:0007417	central nervous system development
3.66	1.19e-11	GO:0031175	neuron projection development
3.82	7.68e-11	GO:0007409	axonogenesis
3.69	2.67e-10	GO:0048667	cell morphogenesis involved in neuron differentiation
3.47	3.21e-10	GO:0000904	cell morphogenesis involved in differentiation
3.62	4.88e-10	GO:0048812	neuron projection morphogenesis
3.38	1.63e-09	GO:0048858	cell projection morphogenesis
4.36	2.02e-09	GO:0051960	regulation of nervous system development
3.35	2.22e-09	GO:0032990	cell part morphogenesis
3.03	3.03e-09	GO:0030030	cell projection organization
3.11	3.24e-09	GO:0000902	cell morphogenesis
3.01	6.30e-09	GO:0032989	cellular component morphogenesis
2.90	9.27e-09	GO:0045595	regulation of cell differentiation
3.96	1.45e-08	GO:0060284	regulation of cell development
2.54	3.35e-08	GO:0050793	regulation of developmental process
1.39	5.93e-08	GO:0050794	regulation of cellular process
4.68	1.05e-07	GO:0045664	regulation of neuron differentiation
4.97	1.59e-07	GO:0030900	forebrain development
4.16	3.16e-07	GO:0050767	regulation of neurogenesis
3.48	4.79e-07	GO:0007420	brain development
3.07	5.46e-07	GO:0030001	metal ion transport
2.16	5.86e-07	GO:0051239	regulation of multicellular organismal process
1.34	8.89e-07	GO:0050789	regulation of biological process
2.43	9.32e-07	GO:0006811	ion transport
4.95	1.07e-06	GO:0006813	potassium ion transport
2.57	1.13e-06	GO:2000026	regulation of multicellular organismal development
1.32	2.16e-06	GO:0065007	biological regulation
1.60	4.11e-06	GO:0007165	signal transduction
3.90	1.15e-05	GO:0048568	embryonic organ development
3.57	2.05e-05	GO:0035295	tube development
1.82	2.52e-05	GO:0048513	organ development
1.86	3.38e-05	GO:0003008	system process
3.25	4.67e-05	GO:0015672	monovalent inorganic cation transport
2.62	5.54e-05	GO:0006812	cation transport
2.35	9.18e-05	GO:0007155	cell adhesion
2.35	9.18e-05	GO:0022610	biological adhesion
3.49	1.09e-04	GO:0045596	negative regulation of cell differentiation
3.19	1.21e-04	GO:0051093	negative regulation of developmental process
3.12	1.96e-04	GO:0007411	axon guidance
2.11	2.46e-04	GO:0009605	response to external stimulus
2.20	2.52e-04	GO:0040011	locomotion
11.89	2.90e-04	GO:0050807	regulation of synapse organization
3.13	3.08e-04	GO:0001501	skeletal system development
2.35	3.37e-04	GO:0009790	embryo development
2.10	3.90e-04	GO:0032879	regulation of localization
2.46	4.10e-04	GO:0009887	organ morphogenesis
4.24	9.26e-04	GO:0031644	regulation of neurological system process
10.13	1.18e-03	GO:0050803	regulation of synapse structure and activity
4.62	1.43e-03	GO:0060541	respiratory system development
4.09	1.55e-03	GO:0045165	cell fate commitment
5.78	1.59e-03	GO:0048565	digestive tract development
4.58	1.61e-03	GO:0050804	regulation of synaptic transmission
9.77	1.62e-03	GO:0021954	central nervous system neuron development
2.81	1.68e-03	GO:0048598	embryonic morphogenesis
4.04	1.88e-03	GO:0031344	regulation of cell projection organization
2.49	1.90e-03	GO:0006935	chemotaxis
2.49	1.90e-03	GO:0042330	taxis
3.00	1.94e-03	GO:0022603	regulation of anatomical structure morphogenesis
9.43	2.17e-03	GO:0071804	cellular potassium ion transport
9.43	2.17e-03	GO:0071805	potassium ion transmembrane transport
2.59	2.46e-03	GO:0051094	positive regulation of developmental process
2.88	2.60e-03	GO:0044057	regulation of system process
1.82	2.67e-03	GO:0050877	neurological system process
4.31	3.51e-03	GO:0010959	regulation of metal ion transport
4.94	3.58e-03	GO:0021537	telencephalon development
4.56	3.90e-03	GO:0048736	appendage development
4.56	3.90e-03	GO:0060173	limb development
4.28	3.91e-03	GO:0010975	regulation of neuron projection development
4.89	4.07e-03	GO:0048839	inner ear development
4.78	5.22e-03	GO:0030324	lung development
2.99	5.46e-03	GO:0007423	sensory organ development
5.13	5.88e-03	GO:0055123	digestive system development
4.14	5.91e-03	GO:0051969	regulation of transmission of nerve impulse
4.39	6.12e-03	GO:0043583	ear development
2.69	6.16e-03	GO:0009792	embryo development ending in birth or egg hatching
1.67	6.46e-03	GO:0007166	cell surface receptor linked signaling pathway
3.88	6.56e-03	GO:0043269	regulation of ion transport
2.94	7.49e-03	GO:0001944	vasculature development
4.63	7.50e-03	GO:0030323	respiratory tube development
3.02	7.55e-03	GO:0001568	blood vessel development
4.04	7.98e-03	GO:0042391	regulation of membrane potential
3.20	8.82e-03	GO:0002009	morphogenesis of an epithelium
1.39	9.70e-03	GO:0051716	cellular response to stimulus
3.42	1.02e-02	GO:0034220	ion transmembrane transport
4.40	1.33e-02	GO:0035107	appendage morphogenesis
4.40	1.33e-02	GO:0035108	limb morphogenesis
11.40	1.43e-02	GO:0007214	gamma-aminobutyric acid signaling pathway
2.82	1.46e-02	GO:0016337	cell-cell adhesion
2.62	1.49e-02	GO:0043009	chordate embryonic development
3.08	1.53e-02	GO:0003002	regionalization
4.32	1.65e-02	GO:0061138	morphogenesis of a branching epithelium
4.61	1.83e-02	GO:0030326	embryonic limb morphogenesis
4.61	1.83e-02	GO:0035113	embryonic appendage morphogenesis
2.38	1.98e-02	GO:0072358	cardiovascular system development
2.38	1.98e-02	GO:0072359	circulatory system development
10.80	2.04e-02	GO:0051963	regulation of synaptogenesis
3.92	2.31e-02	GO:0010769	regulation of cell morphogenesis involved in differentiation
2.67	2.41e-02	GO:0045597	positive regulation of cell differentiation
3.89	2.53e-02	GO:0022604	regulation of cell morphogenesis
1.99	2.75e-02	GO:0051128	regulation of cellular component organization
6.84	2.93e-02	GO:0051899	membrane depolarization
3.83	3.05e-02	GO:0048705	skeletal system morphogenesis
5.26	3.05e-02	GO:0042472	inner ear morphogenesis
2.05	3.52e-02	GO:0051049	regulation of transport
4.32	3.58e-02	GO:0048754	branching morphogenesis of a tube
2.60	3.67e-02	GO:0007389	pattern specification process
3.21	4.17e-02	GO:0048732	gland development
1.83	4.26e-02	GO:0010646	regulation of cell communication
2.71	4.30e-02	GO:0048729	tissue morphogenesis
2.10	4.35e-02	GO:0007167	enzyme linked receptor protein signaling pathway

Gene overrepresentation in compartment category:

Enrichment	P-value	GO Accession	GO Term
2.13	8.01e-15	GO:0044459	plasma membrane part
1.70	2.10e-13	GO:0005886	plasma membrane
3.97	6.80e-13	GO:0045202	synapse
1.67	9.63e-13	GO:0071944	cell periphery
2.35	1.04e-10	GO:0031226	intrinsic to plasma membrane
2.36	1.06e-10	GO:0005887	integral to plasma membrane
4.93	1.24e-10	GO:0034702	ion channel complex
2.96	2.94e-09	GO:0030054	cell junction
3.48	3.18e-09	GO:0043005	neuron projection
3.92	5.49e-09	GO:0044456	synapse part
5.31	1.44e-08	GO:0045211	postsynaptic membrane
1.38	1.74e-07	GO:0044425	membrane part
1.32	4.55e-07	GO:0016020	membrane
3.22	5.32e-07	GO:0031012	extracellular matrix
5.07	6.13e-07	GO:0034703	cation channel complex
1.41	1.61e-06	GO:0031224	intrinsic to membrane
4.18	1.77e-06	GO:0030425	dendrite
4.28	2.53e-06	GO:0030424	axon
2.81	4.10e-05	GO:0044463	cell projection part
5.50	5.36e-05	GO:0008076	voltage-gated potassium channel complex
5.50	5.36e-05	GO:0034705	potassium channel complex
1.36	5.98e-05	GO:0016021	integral to membrane
2.91	3.11e-04	GO:0005578	proteinaceous extracellular matrix
2.05	4.08e-04	GO:0042995	cell projection
5.88	5.47e-04	GO:0030426	growth cone
5.70	7.50e-04	GO:0030427	site of polarized growth
4.95	3.07e-03	GO:0033267	axon part
1.84	4.33e-03	GO:0044421	extracellular region part
3.77	5.26e-03	GO:0031225	anchored to membrane
5.70	5.95e-03	GO:0034707	chloride channel complex
1.54	7.31e-03	GO:0005576	extracellular region
3.22	1.01e-02	GO:0043025	neuronal cell body
3.13	1.43e-02	GO:0044297	cell body
6.47	2.08e-02	GO:0042734	presynaptic membrane
3.80	3.69e-02	GO:0019717	synaptosome

Gene overrepresentation in function category:

Enrichment	P-value	GO Accession	GO Term
4.11	2.46e-14	GO:0015267	channel activity
4.10	2.72e-14	GO:0022803	passive transmembrane transporter activity
4.66	6.34e-14	GO:0022836	gated channel activity
4.13	9.82e-14	GO:0005216	ion channel activity
4.07	1.80e-13	GO:0022838	substrate-specific channel activity
4.28	7.00e-10	GO:0005261	cation channel activity
5.70	3.61e-08	GO:0005267	potassium channel activity
5.30	5.63e-08	GO:0022843	voltage-gated cation channel activity
2.57	1.10e-07	GO:0015075	ion transmembrane transporter activity
4.39	4.41e-07	GO:0005244	voltage-gated ion channel activity
4.39	4.41e-07	GO:0022832	voltage-gated channel activity
2.19	7.53e-06	GO:0022857	transmembrane transporter activity
4.92	8.54e-06	GO:0015276	ligand-gated ion channel activity
4.92	8.54e-06	GO:0022834	ligand-gated channel activity
2.20	2.22e-05	GO:0022891	substrate-specific transmembrane transporter activity
1.99	2.39e-05	GO:0005215	transporter activity
12.43	3.93e-05	GO:0016917	GABA receptor activity
6.17	5.06e-05	GO:0005230	extracellular ligand-gated ion channel activity
5.23	5.51e-05	GO:0005249	voltage-gated potassium channel activity
2.49	6.22e-05	GO:0008324	cation transmembrane transporter activity
2.00	2.22e-04	GO:0022892	substrate-specific transporter activity
12.60	2.26e-04	GO:0004890	GABA-A receptor activity
5.97	6.54e-04	GO:0004714	transmembrane receptor protein tyrosine kinase activity
5.13	1.19e-03	GO:0005201	extracellular matrix structural constituent
22.79	3.56e-03	GO:0008503	benzodiazepine receptor activity
8.55	4.22e-03	GO:0008066	glutamate receptor activity
4.64	8.00e-03	GO:0019199	transmembrane receptor protein kinase activity
25.64	3.34e-02	GO:0004157	dihydropyrimidinase activity
7.60	3.68e-02	GO:0019905	syntaxin binding
3.26	3.73e-02	GO:0005539	glycosaminoglycan binding
1.49	4.44e-02	GO:0004871	signal transducer activity
1.49	4.44e-02	GO:0060089	molecular transducer activity
9.50	4.52e-02	GO:0005234	extracellular-glutamate-gated ion channel activity