Motif ID: GUAACAG

Z-value: 1.149


Mature miRNA associated with seed GUAACAG:

NamemiRBase Accession
hsa-miR-194 MIMAT0000460



Activity profile for motif GUAACAG.

activity profile for motif GUAACAG


Sorted Z-values histogram for motif GUAACAG

Sorted Z-values for motif GUAACAG



Network of associatons between targets according to the STRING database.



First level regulatory network of GUAACAG

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr17_-_36105005 3.223 NM_000458
NM_001165923
 HNF1B

HNF1 homeobox B

chr6_+_133562488 3.137 NM_004100
NM_172103
NM_172105
 EYA4


eyes absent homolog 4 (Drosophila)


chr11_+_12695851 3.094 NM_021961
 TEAD1
TEA domain family member 1 (SV40 transcriptional enhancer factor)
chr3_-_126076057 2.870 NM_014079
 KLF15
Kruppel-like factor 15
chr8_+_55370494 2.641 NM_022454
 SOX17
SRY (sex determining region Y)-box 17
chr15_+_96875793 2.512 NM_001145156
 NR2F2
nuclear receptor subfamily 2, group F, member 2
chr15_+_96873845 2.496 NM_021005
 NR2F2
nuclear receptor subfamily 2, group F, member 2
chr15_+_96869156 2.326 NM_001145155
 NR2F2
nuclear receptor subfamily 2, group F, member 2
chr1_-_178840079 2.260 NM_004673
 ANGPTL1
angiopoietin-like 1
chr11_-_17410205 2.235 NM_000525
 KCNJ11
potassium inwardly-rectifying channel, subfamily J, member 11
chr11_-_17410863 2.217 NM_001166290
 KCNJ11
potassium inwardly-rectifying channel, subfamily J, member 11
chr1_+_82266081 2.216 NM_012302
 LPHN2
latrophilin 2
chr14_-_38064440 2.200 NM_004496
 FOXA1
forkhead box A1
chr11_-_16424391 2.087 NM_001145819
NM_017508
 SOX6

SRY (sex determining region Y)-box 6

chr15_+_96876568 1.999 NM_001145157
 NR2F2
nuclear receptor subfamily 2, group F, member 2
chr11_-_16497917 1.924 NM_033326
 SOX6
SRY (sex determining region Y)-box 6
chr19_-_46272496 1.896 NM_175875
 SIX5
SIX homeobox 5
chr16_-_73092533 1.859 NM_001164766
 ZFHX3
zinc finger homeobox 3
chr11_-_16430425 1.828 NM_001145811
 SOX6
SRY (sex determining region Y)-box 6
chr1_-_225840660 1.819 NM_001008493
NM_018212
 ENAH

enabled homolog (Drosophila)


Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 34 entries
Enrichment   P-value GO Accession GO Term
301.57 5.06e-03 GO:0060677 ureteric bud elongation
14.88 1.86e-04 GO:0045165 cell fate commitment
10.56 4.97e-02 GO:0060562 epithelial tube morphogenesis
8.17 9.98e-03 GO:0035295 tube development
6.34 4.99e-02 GO:0007420 brain development
5.62 3.61e-02 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
5.62 3.61e-02 GO:0072358 cardiovascular system development
5.62 3.61e-02 GO:0072359 circulatory system development
5.38 5.94e-03 GO:0045893 positive regulation of transcription, DNA-dependent
5.03 2.91e-02 GO:0009887 organ morphogenesis
5.02 1.09e-02 GO:0051254 positive regulation of RNA metabolic process
4.97 1.19e-02 GO:0010628 positive regulation of gene expression
4.95 4.52e-03 GO:0010557 positive regulation of macromolecule biosynthetic process
4.80 2.27e-03 GO:0031328 positive regulation of cellular biosynthetic process
4.72 2.70e-03 GO:0009891 positive regulation of biosynthetic process
4.43 3.17e-02 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
4.30 4.08e-02 GO:0051173 positive regulation of nitrogen compound metabolic process
4.13 1.05e-02 GO:0006357 regulation of transcription from RNA polymerase II promoter
3.58 8.10e-05 GO:0048513 organ development
3.17 3.67e-02 GO:0009653 anatomical structure morphogenesis

Gene overrepresentation in compartment category:

Showing 1 to 3 of 3 entries
Enrichment   P-value GO Accession GO Term
5.46 2.07e-02 GO:0045202 synapse
2.38 4.82e-02 GO:0044459 plasma membrane part
1.90 4.23e-02 GO:0005886 plasma membrane

Gene overrepresentation in function category:

Showing 1 to 14 of 14 entries
Enrichment   P-value GO Accession GO Term
86.18 2.11e-02 GO:0000982 RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity
86.18 2.11e-02 GO:0001077 RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
16.23 1.26e-03 GO:0000981 sequence-specific DNA binding RNA polymerase II transcription factor activity
14.38 1.58e-02 GO:0003705 sequence-specific enhancer binding RNA polymerase II transcription factor activity
12.08 3.09e-02 GO:0005057 receptor signaling protein activity
7.79 4.11e-02 GO:0010843 promoter binding
7.48 4.94e-02 GO:0000975 regulatory region DNA binding
7.48 4.94e-02 GO:0001067 regulatory region nucleic acid binding
7.48 4.94e-02 GO:0044212 transcription regulatory region DNA binding
6.87 6.03e-03 GO:0016563 transcription activator activity
4.56 1.15e-04 GO:0001071 nucleic acid binding transcription factor activity
4.56 1.15e-04 GO:0003700 sequence-specific DNA binding transcription factor activity
4.14 8.79e-04 GO:0030528 transcription regulator activity
1.31 2.59e-02 GO:0005488 binding