Motif ID: GUAGUGU

Z-value: 1.780


Mature miRNA associated with seed GUAGUGU:

NamemiRBase Accession
hsa-miR-142-3p MIMAT0000434



Activity profile for motif GUAGUGU.

activity profile for motif GUAGUGU


Sorted Z-values histogram for motif GUAGUGU

Sorted Z-values for motif GUAGUGU



Network of associatons between targets according to the STRING database.



First level regulatory network of GUAGUGU

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr5_-_101631965 7.125 NM_180991
SLCO4C1
solute carrier organic anion transporter family, member 4C1
chr7_+_50344255 6.474 NM_001220765
NM_001220766
NM_001220767
NM_001220768
NM_001220769
NM_001220770
NM_001220771
NM_001220772
NM_001220773
NM_001220774
NM_001220775
NM_001220776
NM_006060
IKZF1












IKAROS family zinc finger 1 (Ikaros)












chrX_+_49832214 5.509 NM_000084
CLCN5
chloride channel 5
chr4_-_40631846 5.334 NM_001098634
RBM47
RNA binding motif protein 47
chr6_-_91006580 5.275 NM_001170794
BACH2
BTB and CNC homology 1, basic leucine zipper transcription factor 2
chr6_-_91006460 5.246 NM_021813
BACH2
BTB and CNC homology 1, basic leucine zipper transcription factor 2
chr21_-_44846927 4.679 NM_173354
SIK1
salt-inducible kinase 1
chr5_+_49962771 4.672 NM_001178056
NM_024615
PARP8

poly (ADP-ribose) polymerase family, member 8

chr20_+_57766074 4.606 NM_178457
ZNF831
zinc finger protein 831
chr21_+_30671736 4.595 NM_206866
BACH1
BTB and CNC homology 1, basic leucine zipper transcription factor 1
chr2_-_145277879 4.436 NM_001171653
NM_014795
ZEB2

zinc finger E-box binding homeobox 2

chr14_-_35344852 4.339 NM_013448
NM_182648
BAZ1A

bromodomain adjacent to zinc finger domain, 1A

chrX_+_9432980 4.334 NM_005647
TBL1X
transducin (beta)-like 1X-linked
chr20_-_52199635 4.289 NM_006526
ZNF217
zinc finger protein 217
chr1_-_92951593 4.236 NM_001127216
GFI1
growth factor independent 1 transcription repressor
chr1_-_92952429 4.164 NM_005263
GFI1
growth factor independent 1 transcription repressor
chr12_+_57916607 4.096 NM_052897
MBD6
methyl-CpG binding domain protein 6
chr5_-_39074494 3.908 NM_152756
RICTOR
RPTOR independent companion of MTOR, complex 2
chr1_-_29450406 3.768 NM_001003682
TMEM200B
transmembrane protein 200B
chrX_+_49687212 3.756 NM_001127898
NM_001127899
CLCN5

chloride channel 5

chr2_-_161350304 3.643 NM_002897
NM_016836
RBMS1

RNA binding motif, single stranded interacting protein 1

chr5_-_90679115 3.620 NM_020801
ARRDC3
arrestin domain containing 3
chr10_-_60027630 3.601 NM_152230
IPMK
inositol polyphosphate multikinase
chr11_+_111473099 3.575 NM_015191
SIK2
salt-inducible kinase 2
chrX_-_108976509 3.559 NM_004458
NM_022977
ACSL4

acyl-CoA synthetase long-chain family member 4

chr13_-_41240607 3.551 NM_002015
FOXO1
forkhead box O1
chr6_+_144612872 3.470 NM_007124
UTRN
utrophin
chr10_-_65028825 3.461 NM_004241
JMJD1C
jumonji domain containing 1C
chr1_-_92949355 3.455 NM_001127215
GFI1
growth factor independent 1 transcription repressor
chr12_+_122242580 3.447 NM_015048
SETD1B
SET domain containing 1B
chr7_+_101460881 3.445 NM_181552
CUX1
cut-like homeobox 1
chr1_-_29449012 3.435 NM_001171868
TMEM200B
transmembrane protein 200B
chr15_-_78369825 3.403 NM_015079
NM_144572
TBC1D2B

TBC1 domain family, member 2B

chr4_-_40517913 3.386 NM_019027
RBM47
RNA binding motif protein 47
chr15_+_31619043 3.252 NM_015995
KLF13
Kruppel-like factor 13
chr2_-_87035518 3.232 NM_001145873
CD8A
CD8a molecule
chr3_+_63884074 3.231 NM_001177387
ATXN7
ataxin 7
chr11_+_122709205 3.222 NM_019604
CRTAM
cytotoxic and regulatory T cell molecule
chr5_+_49961732 3.176 NM_001178055
PARP8
poly (ADP-ribose) polymerase family, member 8
chr2_-_87018802 3.142 NM_001768
NM_171827
CD8A

CD8a molecule

chr2_-_99347588 3.139 NM_012214
MGAT4A
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
chr4_+_87856152 3.050 NM_001166693
AFF1
AF4/FMR2 family, member 1
chr6_+_7107986 3.034 NM_001003698
NM_001003699
NM_001003700
RREB1


ras responsive element binding protein 1


chr7_-_5463176 3.005 NM_001080495
TNRC18
trinucleotide repeat containing 18
chr11_+_57529233 2.978 NM_001085458
NM_001085459
NM_001085460
NM_001085461
NM_001085462
NM_001085463
NM_001085464
NM_001085465
NM_001085466
NM_001085467
NM_001085468
NM_001085469
NM_001206883
NM_001206884
NM_001206885
NM_001206886
NM_001206887
NM_001206888
NM_001206889
NM_001206890
NM_001206891
NM_001331
CTNND1





















catenin (cadherin-associated protein), delta 1





















chrX_-_153285334 2.956 NM_001025242
NM_001025243
NM_001569
IRAK1


interleukin-1 receptor-associated kinase 1


chr21_+_30671217 2.916 NM_001186
BACH1
BTB and CNC homology 1, basic leucine zipper transcription factor 1
chr6_+_163835668 2.887 NM_006775
NM_206853
NM_206854
NM_206855
QKI



QKI, KH domain containing, RNA binding



chr16_-_4166185 2.840 NM_001116
ADCY9
adenylate cyclase 9
chr18_+_42260774 2.809 NM_015559
SETBP1
SET binding protein 1
chr6_+_34206567 2.776 NM_145905
HMGA1
high mobility group AT-hook 1
chr5_-_142783975 2.732 NM_001018076
NR3C1
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr1_-_160549271 2.708 NM_001184879
NM_001184881
NM_001184882
NM_003874
CD84



CD84 molecule



chr17_-_47439326 2.695 NM_001145365
NM_014897
ZNF652

zinc finger protein 652

chr4_+_87928083 2.688 NM_005935
AFF1
AF4/FMR2 family, member 1
chr18_+_57567191 2.625 NM_021127
PMAIP1
phorbol-12-myristate-13-acetate-induced protein 1
chr4_-_164534656 2.586 NM_017923
MARCH1
membrane-associated ring finger (C3HC4) 1
chr10_+_98592658 2.505 NM_032440
LCOR
ligand dependent nuclear receptor corepressor
chr16_+_10971038 2.489 NM_000246
CIITA
class II, major histocompatibility complex, transactivator
chr6_+_114178516 2.464 NM_002356
MARCKS
myristoylated alanine-rich protein kinase C substrate
chr16_+_28986024 2.462 NM_001142448
NM_001142449
NM_001142450
NM_001142451
NM_032038
SPIN1
SPNS1




spindlin 1
spinster homolog 1 (Drosophila)




chr3_+_63953419 2.457 NM_001128149
ATXN7
ataxin 7
chr5_-_142815076 2.410 NM_001018074
NM_001018075
NM_001018077
NR3C1


nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)


chr10_+_97803064 2.395 NM_001134375
NM_001134376
NM_019084
CCNJ


cyclin J


chr3_-_151047309 2.332 NM_176894
P2RY13
purinergic receptor P2Y, G-protein coupled, 13
chr6_+_7107799 2.327 NM_001168344
RREB1
ras responsive element binding protein 1
chr13_+_49684388 2.304 NM_014923
FNDC3A
fibronectin type III domain containing 3A
chr6_-_159466019 2.252 NM_054114
NM_138810
NM_152133
TAGAP


T-cell activation RhoGTPase activating protein


chr2_+_74273449 2.252 NM_144993
TET3
tet methylcytosine dioxygenase 3
chr12_+_1100352 2.239 NM_178039
NM_178040
ERC1

ELKS/RAB6-interacting/CAST family member 1

chr2_-_43453737 2.235 NM_006887
ZFP36L2
zinc finger protein 36, C3H type-like 2
chr19_+_16187047 2.219 NM_003290
TPM4
tropomyosin 4
chr22_-_36784055 2.174 NM_002473
MYH9
myosin, heavy chain 9, non-muscle
chr18_+_67956136 2.162 NM_004232
SOCS6
suppressor of cytokine signaling 6
chr19_-_17356022 2.156 NM_005234
NR2F6
nuclear receptor subfamily 2, group F, member 6
chr12_-_53625834 2.108 NM_000966
NM_001243730
NM_001243731
RARG


retinoic acid receptor, gamma


chr11_-_65381641 2.100 NM_002419
MAP3K11
mitogen-activated protein kinase kinase kinase 11
chr5_+_53813494 2.072 NM_001145427
NM_001102575
NM_052870
SNX18


sorting nexin 18


chrX_+_9431314 2.069 NM_001139466
NM_001139467
NM_001139468
TBL1X


transducin (beta)-like 1X-linked


chr12_-_53614121 2.065 NM_001042728
NM_001243732
RARG

retinoic acid receptor, gamma

chr1_+_64088886 2.056 NM_001172818
PGM1
phosphoglucomutase 1
chr16_-_87525317 2.038 NM_015144
ZCCHC14
zinc finger, CCHC domain containing 14
chr13_+_28712379 2.022 NM_175854
PAN3
PAN3 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)
chr1_+_64059479 2.016 NM_001172819
PGM1
phosphoglucomutase 1
chr10_-_65225605 2.015 NM_032776
JMJD1C
jumonji domain containing 1C
chr10_-_61666236 2.011 NM_005436
CCDC6
coiled-coil domain containing 6
chr19_+_54695103 2.005 NM_001077446
TSEN34
tRNA splicing endonuclease 34 homolog (S. cerevisiae)
chr17_-_48474910 2.001 NM_018509
LRRC59
leucine rich repeat containing 59
chr5_-_88199868 1.988 NM_001131005
NM_001193347
MEF2C

myocyte enhancer factor 2C

chr19_+_56187990 1.988 NM_001130071
EPN1
epsin 1
chr14_-_31676680 1.925 NM_015382
HECTD1
HECT domain containing 1
chr3_-_176915012 1.923 NM_024665
TBL1XR1
transducin (beta)-like 1 X-linked receptor 1
chr10_+_98592015 1.890 NM_001170765
NM_001170766
LCOR

ligand dependent nuclear receptor corepressor

chr17_+_73521744 1.884 NM_001015002
NM_001031803
NM_004524
LLGL2


lethal giant larvae homolog 2 (Drosophila)


chr16_+_67143783 1.862 NM_025187
C16orf70
chromosome 16 open reading frame 70
chr4_-_165304406 1.840 NM_001166373
MARCH1
membrane-associated ring finger (C3HC4) 1
chr3_+_63850181 1.819 NM_000333
ATXN7
ataxin 7
chr7_+_21467572 1.819 NM_003112
SP4
Sp4 transcription factor
chr5_-_88119604 1.814 NM_001193348
NM_001193349
MEF2C

myocyte enhancer factor 2C

chr6_+_149639435 1.794 NM_015093
TAB2
TGF-beta activated kinase 1/MAP3K7 binding protein 2
chr1_+_87170222 1.758 NM_001206651
NM_001206652
NM_001206653
NM_016009
SH3GLB1



SH3-domain GRB2-like endophilin B1



chr10_+_11047253 1.756 NM_001025077
CELF2
CUGBP, Elav-like family member 2
chr11_+_120207617 1.754 NM_001198665
NM_015313
ARHGEF12

Rho guanine nucleotide exchange factor (GEF) 12

chr6_-_134639195 1.742 NM_001143676
SGK1
serum/glucocorticoid regulated kinase 1
chr2_-_65357249 1.740 NM_004161
NM_015543
RAB1A

RAB1A, member RAS oncogene family

chr17_-_48785016 1.730 NM_052855
ANKRD40
ankyrin repeat domain 40
chr4_+_113066552 1.692 NM_152400
C4orf32
chromosome 4 open reading frame 32
chr2_+_198380294 1.692 NM_199482
MOB4
MOB family member 4, phocein
chrY_-_15592549 1.682 NM_007125
NM_182659
NM_182660
UTY


ubiquitously transcribed tetratricopeptide repeat gene, Y-linked


chr17_-_8770976 1.663 NM_001010855
PIK3R6
phosphoinositide-3-kinase, regulatory subunit 6
chr19_-_11450254 1.643 NM_004283
RAB3D
RAB3D, member RAS oncogene family
chr1_-_204380903 1.643 NM_032833
PPP1R15B
protein phosphatase 1, regulatory subunit 15B
chr22_+_37678423 1.641 NM_013385
CYTH4
cytohesin 4
chr11_+_13299260 1.639 NM_001030272
NM_001030273
NM_001178
ARNTL


aryl hydrocarbon receptor nuclear translocator-like


chr3_+_187943192 1.638 NM_001167671
LPP
LIM domain containing preferred translocation partner in lipoma
chr1_-_31538553 1.637 NM_001020658
NM_014676
PUM1

pumilio homolog 1 (Drosophila)

chr8_-_116681103 1.626 NM_014112
TRPS1
trichorhinophalangeal syndrome I
chr1_-_184724021 1.612 NM_025191
EDEM3
ER degradation enhancer, mannosidase alpha-like 3
chr6_-_30712294 1.602 NM_003897
IER3
immediate early response 3
chr19_-_15560761 1.588 NM_021241
WIZ
widely interspaced zinc finger motifs
chr6_-_31628509 1.583 NM_021184
C6orf47
chromosome 6 open reading frame 47
chr8_+_81398416 1.566 NM_001105539
NM_023929
ZBTB10

zinc finger and BTB domain containing 10

chr13_-_31040035 1.534 NM_002128
HMGB1
high mobility group box 1
chr13_+_49549953 1.530 NM_001079673
FNDC3A
fibronectin type III domain containing 3A
chr19_+_16178170 1.526 NM_001145160
TPM4
tropomyosin 4
chr3_+_20081523 1.460 NM_003884
KAT2B
K(lysine) acetyltransferase 2B
chrX_+_44732402 1.444 NM_021140
KDM6A
lysine (K)-specific demethylase 6A
chr6_-_74363689 1.441 NM_012434
SLC17A5
solute carrier family 17 (anion/sugar transporter), member 5
chr10_-_11653529 1.428 NM_014688
USP6NL
USP6 N-terminal like
chr1_+_24069855 1.426 NM_003198
TCEB3
transcription elongation factor B (SIII), polypeptide 3 (110kDa, elongin A)
chr20_-_5591487 1.426 NM_019593
GPCPD1
glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae)
chr3_+_187871473 1.425 NM_001167672
LPP
LIM domain containing preferred translocation partner in lipoma
chr10_-_11574273 1.422 NM_001080491
USP6NL
USP6 N-terminal like
chr2_-_61765394 1.394 NM_003400
XPO1
exportin 1 (CRM1 homolog, yeast)
chr17_+_7210841 1.390 NM_001970
EIF5A
eukaryotic translation initiation factor 5A
chr5_+_42550181 1.389 NM_001242405
GHR
growth hormone receptor
chr5_-_55290601 1.370 NM_001190981
NM_002184
NM_175767
IL6ST


interleukin 6 signal transducer (gp130, oncostatin M receptor)


chr3_-_52931595 1.334 NM_001198974
NM_198563
TMEM110-MUSTN1
TMEM110
TMEM110-MUSTN1 readthrough
transmembrane protein 110
chr9_-_80646150 1.327 NM_002072
GNAQ
guanine nucleotide binding protein (G protein), q polypeptide
chr5_+_42548314 1.322 NM_001242403
GHR
growth hormone receptor
chr3_-_112218383 1.310 NM_001085357
NM_181780
BTLA

B and T lymphocyte associated

chr1_+_64058891 1.309 NM_002633
PGM1
phosphoglucomutase 1
chr6_+_34204647 1.306 NM_145901
NM_145902
HMGA1

high mobility group AT-hook 1

chr5_+_42549657 1.304 NM_001242404
GHR
growth hormone receptor
chr7_+_28725597 1.296 NM_001011666
CREB5
cAMP responsive element binding protein 5
chr5_-_142783225 1.292 NM_000176
NM_001020825
NM_001024094
NM_001204258
NM_001204259
NM_001204260
NM_001204261
NM_001204262
NM_001204263
NM_001204264
NM_001204265
NR3C1










nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)










chr6_+_34204576 1.289 NM_002131
NM_145899
NM_145903
HMGA1


high mobility group AT-hook 1


chr1_-_10856704 1.265 NM_001079843
NM_017766
CASZ1

castor zinc finger 1

chr22_+_46546498 1.260 NM_001001928
NM_005036
PPARA

peroxisome proliferator-activated receptor alpha

chr14_+_52781004 1.259 NM_000956
PTGER2
prostaglandin E receptor 2 (subtype EP2), 53kDa
chr7_+_100271309 1.256 NM_005273
GNB2
guanine nucleotide binding protein (G protein), beta polypeptide 2
chr7_+_28452143 1.241 NM_182898
CREB5
cAMP responsive element binding protein 5
chr5_+_42565562 1.219 NM_001242406
GHR
growth hormone receptor
chr5_+_42548144 1.213 NM_001242402
GHR
growth hormone receptor
chr5_+_6746100 1.211 NM_001171806
PAPD7
PAP associated domain containing 7
chr6_-_134497069 1.204 NM_001143678
SGK1
serum/glucocorticoid regulated kinase 1
chr1_+_117910052 1.199 NM_006699
MAN1A2
mannosidase, alpha, class 1A, member 2
chr10_+_63661012 1.196 NM_032199
ARID5B
AT rich interactive domain 5B (MRF1-like)
chr11_+_118307072 1.186 NM_001197104
NM_005933
MLL

myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)

chr3_+_122513870 1.185 NM_032839
DIRC2
disrupted in renal carcinoma 2
chr2_-_64371444 1.161 NM_020651
PELI1
pellino homolog 1 (Drosophila)
chrX_-_41782230 1.146 NM_001126054
NM_001126055
NM_003688
CASK


calcium/calmodulin-dependent serine protein kinase (MAGUK family)


chr6_+_152128685 1.142 NM_000125
ESR1
estrogen receptor 1
chr12_-_48298765 1.140 NM_000376
NM_001017535
NM_001017536
VDR


vitamin D (1,25- dihydroxyvitamin D3) receptor


chr12_+_65004191 1.123 NM_178169
RASSF3
Ras association (RalGDS/AF-6) domain family member 3
chr20_-_30310597 1.121 NM_001191
NM_138578
BCL2L1

BCL2-like 1

chr11_-_8680382 1.113 NM_014818
TRIM66
tripartite motif containing 66
chr8_-_28243941 1.099 NM_018660
ZNF395
zinc finger protein 395
chr9_+_5450455 1.098 NM_014143
CD274
CD274 molecule
chr1_+_156163722 1.092 NM_014655
SLC25A44
solute carrier family 25, member 44
chr11_+_126152979 1.089 NM_001039661
NM_148910
TIRAP

toll-interleukin 1 receptor (TIR) domain containing adaptor protein

chr9_+_116638544 1.076 NM_133374
ZNF618
zinc finger protein 618
chr17_+_7211260 1.075 NM_001143761
EIF5A
eukaryotic translation initiation factor 5A
chr11_+_107879407 1.075 NM_003478
CUL5
cullin 5
chr6_+_152126807 1.070 NM_001122741
ESR1
estrogen receptor 1
chr5_-_88179278 1.054 NM_001193350
NM_002397
MEF2C

myocyte enhancer factor 2C

chr17_-_53499055 1.043 NM_012329
MMD
monocyte to macrophage differentiation-associated
chr17_+_7210317 1.037 NM_001143760
EIF5A
eukaryotic translation initiation factor 5A
chr6_-_134496006 1.033 NM_005627
SGK1
serum/glucocorticoid regulated kinase 1
chr22_-_31742217 1.033 NM_014323
NM_032050
NM_032051
NM_032052
PATZ1



POZ (BTB) and AT hook containing zinc finger 1



chr7_+_28475233 1.032 NM_004904
CREB5
cAMP responsive element binding protein 5
chr22_-_42322778 1.032 NM_052945
TNFRSF13C
tumor necrosis factor receptor superfamily, member 13C
chr11_-_85780899 1.029 NM_001206947
PICALM
phosphatidylinositol binding clathrin assembly protein
chr9_-_115095933 1.027 NM_001163788
NM_001163790
NM_001244896
NM_001244897
NM_005156
PTBP3




polypyrimidine tract binding protein 3




chr6_+_152011630 1.026 NM_001122742
ESR1
estrogen receptor 1
chr5_+_42423811 1.011 NM_000163
GHR
growth hormone receptor
chr5_+_42425093 1.007 NM_001242401
GHR
growth hormone receptor
chr5_+_42565963 0.995 NM_001242460
NM_001242461
NM_001242462
GHR


growth hormone receptor


chr14_+_65453439 0.993 NM_002028
FNTB
farnesyltransferase, CAAX box, beta
chr6_-_134498973 0.993 NM_001143677
SGK1
serum/glucocorticoid regulated kinase 1
chr9_-_110252045 0.991 NM_004235
KLF4
Kruppel-like factor 4 (gut)
chr1_+_114493766 0.986 NM_198269
HIPK1
homeodomain interacting protein kinase 1
chr20_+_49348050 0.976 NM_032521
PARD6B
par-6 partitioning defective 6 homolog beta (C. elegans)
chr1_-_179198814 0.962 NM_001136001
NM_001168236
NM_001168237
NM_001168238
NM_007314
ABL2




v-abl Abelson murine leukemia viral oncogene homolog 2




chr6_-_132834165 0.915 NM_003569
STX7
syntaxin 7
chr6_-_88411984 0.913 NM_018064
AKIRIN2
akirin 2
chr9_+_91606349 0.912 NM_005226
S1PR3
sphingosine-1-phosphate receptor 3
chr16_-_18937722 0.911 NM_015092
SMG1
smg-1 homolog, phosphatidylinositol 3-kinase-related kinase (C. elegans)
chr5_+_42424553 0.889 NM_001242399
NM_001242400
GHR

growth hormone receptor

chr1_+_101361589 0.875 NM_001144884
NM_133496
SLC30A7

solute carrier family 30 (zinc transporter), member 7


Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
2.46 2.85e-06 GO:0010468 regulation of gene expression
2.11 1.02e-05 GO:0031323 regulation of cellular metabolic process
2.36 1.12e-05 GO:0031326 regulation of cellular biosynthetic process
2.42 1.20e-05 GO:0010556 regulation of macromolecule biosynthetic process
2.33 1.58e-05 GO:0009889 regulation of biosynthetic process
2.43 1.75e-05 GO:2000112 regulation of cellular macromolecule biosynthetic process
2.10 1.81e-05 GO:0080090 regulation of primary metabolic process
2.13 2.49e-05 GO:0060255 regulation of macromolecule metabolic process
2.30 3.45e-05 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.24 8.39e-05 GO:0051171 regulation of nitrogen compound metabolic process
2.41 8.60e-05 GO:0051252 regulation of RNA metabolic process
2.44 9.72e-05 GO:0006355 regulation of transcription, DNA-dependent
1.95 1.14e-04 GO:0019222 regulation of metabolic process
4.39 2.81e-04 GO:0045892 negative regulation of transcription, DNA-dependent
4.14 2.96e-04 GO:0010629 negative regulation of gene expression
1.57 3.73e-04 GO:0050794 regulation of cellular process
4.30 3.74e-04 GO:0051253 negative regulation of RNA metabolic process
2.24 6.05e-04 GO:0048522 positive regulation of cellular process
4.82 1.12e-03 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
3.54 1.42e-03 GO:0010557 positive regulation of macromolecule biosynthetic process
3.13 1.52e-03 GO:0006357 regulation of transcription from RNA polymerase II promoter
3.85 1.72e-03 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.89 1.97e-03 GO:0010604 positive regulation of macromolecule metabolic process
3.32 2.03e-03 GO:0031328 positive regulation of cellular biosynthetic process
3.80 2.04e-03 GO:0051172 negative regulation of nitrogen compound metabolic process
3.78 2.24e-03 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
1.50 2.37e-03 GO:0050789 regulation of biological process
2.77 2.62e-03 GO:0009893 positive regulation of metabolic process
3.26 2.63e-03 GO:0009891 positive regulation of biosynthetic process
2.07 3.08e-03 GO:0048518 positive regulation of biological process
2.81 3.22e-03 GO:0031325 positive regulation of cellular metabolic process
3.61 4.09e-03 GO:0010558 negative regulation of macromolecule biosynthetic process
1.46 4.14e-03 GO:0065007 biological regulation
33.36 4.27e-03 GO:0043401 steroid hormone mediated signaling pathway
19.55 4.40e-03 GO:0009755 hormone-mediated signaling pathway
13.17 5.20e-03 GO:0034339 regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor
3.53 5.45e-03 GO:0051254 positive regulation of RNA metabolic process
3.50 6.21e-03 GO:0010628 positive regulation of gene expression
3.47 7.06e-03 GO:0031327 negative regulation of cellular biosynthetic process
3.57 9.24e-03 GO:0045893 positive regulation of transcription, DNA-dependent
3.39 9.28e-03 GO:0009890 negative regulation of biosynthetic process
2.15 1.38e-02 GO:0048523 negative regulation of cellular process
4.47 1.40e-02 GO:0010551 regulation of gene-specific transcription from RNA polymerase II promoter
6.16 1.40e-02 GO:0032582 negative regulation of gene-specific transcription
3.02 1.44e-02 GO:0006351 transcription, DNA-dependent
4.09 1.58e-02 GO:0032583 regulation of gene-specific transcription
6.68 2.35e-02 GO:0010553 negative regulation of gene-specific transcription from RNA polymerase II promoter
3.12 2.77e-02 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.02 3.62e-02 GO:0048519 negative regulation of biological process
3.02 4.04e-02 GO:0051173 positive regulation of nitrogen compound metabolic process

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
1.72 1.09e-05 GO:0005634 nucleus
1.31 1.15e-05 GO:0005622 intracellular
1.43 1.20e-04 GO:0043231 intracellular membrane-bounded organelle
1.43 1.28e-04 GO:0043227 membrane-bounded organelle
1.29 3.83e-04 GO:0044424 intracellular part
1.35 6.66e-04 GO:0043229 intracellular organelle
1.35 7.37e-04 GO:0043226 organelle
1.13 4.40e-03 GO:0044464 cell part
1.13 4.43e-03 GO:0005623 cell
125.10 9.38e-03 GO:0005642 annulate lamellae
8.26 1.32e-02 GO:0016585 chromatin remodeling complex
2.96 1.52e-02 GO:0044451 nucleoplasm part
2.25 4.20e-02 GO:0005654 nucleoplasm

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
3.16 7.80e-05 GO:0030528 transcription regulator activity
5.69 8.04e-05 GO:0008134 transcription factor binding
1.99 8.92e-05 GO:0003676 nucleic acid binding
2.25 1.02e-04 GO:0003677 DNA binding
3.70 1.39e-04 GO:0043565 sequence-specific DNA binding
14.72 5.08e-04 GO:0003707 steroid hormone receptor activity
13.91 7.15e-04 GO:0004879 ligand-dependent nuclear receptor activity
2.16 2.29e-03 GO:0008270 zinc ion binding
2.84 2.39e-03 GO:0001071 nucleic acid binding transcription factor activity
2.84 2.39e-03 GO:0003700 sequence-specific DNA binding transcription factor activity
5.81 4.22e-03 GO:0010843 promoter binding
5.58 5.80e-03 GO:0000975 regulatory region DNA binding
5.58 5.80e-03 GO:0001067 regulatory region nucleic acid binding
5.58 5.80e-03 GO:0044212 transcription regulatory region DNA binding
1.23 5.96e-03 GO:0005488 binding
37.53 9.37e-03 GO:0046965 retinoid X receptor binding
31.28 1.70e-02 GO:0042974 retinoic acid receptor binding
1.40 1.97e-02 GO:0005515 protein binding
1.90 2.99e-02 GO:0046914 transition metal ion binding