Motif ID: GUCAGUU

Z-value: 1.121


Mature miRNA associated with seed GUCAGUU:

NamemiRBase Accession
hsa-miR-223 MIMAT0000280



Activity profile for motif GUCAGUU.

activity profile for motif GUCAGUU


Sorted Z-values histogram for motif GUCAGUU

Sorted Z-values for motif GUCAGUU



Network of associatons between targets according to the STRING database.



First level regulatory network of GUCAGUU

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_-_95007139 5.130 NM_001178096
NM_001993
 F3

coagulation factor III (thromboplastin, tissue factor)

chr12_-_21487831 4.115 NM_021094
 SLCO1A2
solute carrier organic anion transporter family, member 1A2
chr5_+_71403040 3.785 NM_005909
 MAP1B
microtubule-associated protein 1B
chr12_-_21548370 3.722 NM_134431
 SLCO1A2
solute carrier organic anion transporter family, member 1A2
chr9_+_132934685 3.465 NM_014286
 NCS1
neuronal calcium sensor 1
chrX_-_13956644 3.269 NM_001001994
 GPM6B
glycoprotein M6B
chr9_-_99801365 3.258 NM_001333
 CTSL2
cathepsin L2
chr9_+_132962871 3.206 NM_001128826
 NCS1
neuronal calcium sensor 1
chrX_-_13835313 3.058 NM_001001995
NM_001001996
NM_005278
 GPM6B


glycoprotein M6B


chr7_+_140774031 2.882 NM_001195278
 LOC100507421
transmembrane protein 178-like
chr6_+_118228688 2.742 NM_001029858
 SLC35F1
solute carrier family 35, member F1
chr1_+_204913353 2.730 NM_001160331
 NFASC
neurofascin
chr14_+_67999915 2.633 NM_020715
 PLEKHH1
pleckstrin homology domain containing, family H (with MyTH4 domain) member 1
chr19_+_54466289 2.500 NM_031895
 CACNG8
calcium channel, voltage-dependent, gamma subunit 8
chr2_-_166930130 2.487 NM_001165963
NM_001165964
NM_006920
 SCN1A


sodium channel, voltage-gated, type I, alpha subunit


chr17_-_8534008 2.366 NM_005964
 MYH10
myosin, heavy chain 10, non-muscle
chr3_-_9291251 2.322 NM_001033117
NM_014850
 SRGAP3

SLIT-ROBO Rho GTPase activating protein 3

chr3_-_149688638 2.244 NM_002628
NM_053024
 PFN2

profilin 2

chr4_-_90759446 2.240 NM_001146055
 SNCA
synuclein, alpha (non A4 component of amyloid precursor)
chr7_-_98467663 2.224 NM_001134450
NM_001134451
NM_152913
 TMEM130


transmembrane protein 130



Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 15 of 15 entries
Enrichment   P-value GO Accession GO Term
10.21 6.95e-06 GO:0007156 homophilic cell adhesion
5.67 3.39e-04 GO:0016337 cell-cell adhesion
4.07 2.79e-03 GO:0019226 transmission of nerve impulse
4.07 2.79e-03 GO:0035637 multicellular organismal signaling
3.97 1.67e-02 GO:0007268 synaptic transmission
3.91 2.64e-05 GO:0007155 cell adhesion
3.91 2.64e-05 GO:0022610 biological adhesion
3.86 5.00e-12 GO:0007399 nervous system development
3.02 3.16e-02 GO:0007267 cell-cell signaling
2.81 1.11e-02 GO:0007154 cell communication
2.15 1.42e-04 GO:0048731 system development
2.02 4.54e-04 GO:0048856 anatomical structure development
1.97 3.77e-04 GO:0007275 multicellular organismal development
1.86 1.11e-03 GO:0032502 developmental process
1.67 1.19e-03 GO:0032501 multicellular organismal process

Gene overrepresentation in compartment category:

Showing 1 to 18 of 18 entries
Enrichment   P-value GO Accession GO Term
9.50 2.65e-02 GO:0030426 growth cone
9.21 3.06e-02 GO:0030427 site of polarized growth
6.33 2.22e-06 GO:0044456 synapse part
6.27 8.67e-09 GO:0045202 synapse
5.53 1.53e-02 GO:0030424 axon
4.45 4.90e-04 GO:0043005 neuron projection
3.71 2.90e-02 GO:0031012 extracellular matrix
3.44 2.55e-03 GO:0030054 cell junction
2.68 1.93e-02 GO:0042995 cell projection
2.48 4.67e-03 GO:0031226 intrinsic to plasma membrane
2.45 4.07e-06 GO:0044459 plasma membrane part
2.42 1.01e-02 GO:0005887 integral to plasma membrane
1.87 1.71e-05 GO:0071944 cell periphery
1.87 2.59e-05 GO:0005886 plasma membrane
1.78 2.61e-06 GO:0016021 integral to membrane
1.77 2.41e-06 GO:0031224 intrinsic to membrane
1.73 1.90e-07 GO:0044425 membrane part
1.58 9.36e-07 GO:0016020 membrane

Gene overrepresentation in function category:

Showing 1 to 2 of 2 entries
Enrichment   P-value GO Accession GO Term
4.26 9.22e-03 GO:0003779 actin binding
3.88 3.36e-05 GO:0005509 calcium ion binding