Motif ID: HBP1_HMGB_SSRP1_UBTF.p2

Z-value: 1.607


Transcription factors associated with HBP1_HMGB_SSRP1_UBTF.p2:

Gene SymbolEntrez IDGene Name
HBP1 26959 HMG-box transcription factor 1
HMGB2 3148 high-mobility group box 2
HMGB3 3149 high-mobility group box 3
SSRP1 6749 structure specific recognition protein 1
UBTF 7343 upstream binding transcription factor, RNA polymerase I

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
HMGB2hg19_v1_chr4_-_174255454_1742556040.568.3e-04Click!
UBTFhg19_v1_chr17_-_42298881_422989930.551.2e-03Click!
SSRP1hg19_v1_chr11_-_57103324_571033750.346.0e-02Click!
HMGB3hg19_v1_chrX_+_150151757_150151857-0.327.2e-02Click!
HBP1hg19_v1_chr7_+_106809405_1068094740.241.8e-01Click!


Activity profile for motif HBP1_HMGB_SSRP1_UBTF.p2.

activity profile for motif HBP1_HMGB_SSRP1_UBTF.p2


Sorted Z-values histogram for motif HBP1_HMGB_SSRP1_UBTF.p2

Sorted Z-values for motif HBP1_HMGB_SSRP1_UBTF.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of HBP1_HMGB_SSRP1_UBTF.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_-_83824216 6.534 NM_006080
 SEMA3A
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr11_+_112831968 6.182 NM_000615
NM_001076682
NM_001242607
NM_001242608
NM_181351
 NCAM1




neural cell adhesion molecule 1




chr8_-_82395401 6.003 NM_001442
 FABP4
fatty acid binding protein 4, adipocyte
chr15_+_49715374 5.662 NM_002009
 FGF7
fibroblast growth factor 7
chr8_-_108510094 5.308 NM_001146
NM_001199859
 ANGPT1

angiopoietin 1

chr6_-_139613114 5.100 NM_153235
 TXLNB
taxilin beta
chr8_-_124553448 4.986 NM_001242463
NM_058229
 FBXO32

F-box protein 32

chr11_+_112832089 4.797 NCAM1
neural cell adhesion molecule 1
chr8_-_124553253 4.762 FBXO32
F-box protein 32
chrX_+_100333835 4.507 NM_021637
 TMEM35
transmembrane protein 35
chr5_-_44388666 4.292 NM_004465
 FGF10
fibroblast growth factor 10
chrX_+_99839789 4.069 NM_022144
 TNMD
tenomodulin
chr12_-_16757944 3.963 LMO3
LIM domain only 3 (rhombotin-like 2)
chrX_+_135251454 3.800 NM_001159704
 FHL1
four and a half LIM domains 1
chr18_-_53071225 3.510 NM_001243232
 TCF4
transcription factor 4
chr12_-_16759531 3.461 NM_018640
 LMO3
LIM domain only 3 (rhombotin-like 2)
chr19_+_13134782 3.362 NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr12_-_16760935 3.359 NM_001001395
NM_001243609
 LMO3

LIM domain only 3 (rhombotin-like 2)

chr12_-_16759430 3.346 LMO3
LIM domain only 3 (rhombotin-like 2)
chr12_-_8815266 3.324 MFAP5
microfibrillar associated protein 5

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 48 entries
Enrichment   P-value GO Accession GO Term
43.87 2.69e-02 GO:0048251 elastic fiber assembly
43.87 2.69e-02 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis
19.50 4.49e-02 GO:0034394 protein localization at cell surface
12.61 4.51e-02 GO:0010811 positive regulation of cell-substrate adhesion
9.14 1.16e-02 GO:0010810 regulation of cell-substrate adhesion
7.08 5.48e-03 GO:0030324 lung development
6.86 7.13e-03 GO:0030323 respiratory tube development
6.70 2.61e-04 GO:0007156 homophilic cell adhesion
5.93 2.33e-02 GO:0060541 respiratory system development
5.59 5.04e-03 GO:0043062 extracellular structure organization
5.09 1.23e-02 GO:0006936 muscle contraction
4.72 6.13e-05 GO:0016337 cell-cell adhesion
4.68 2.72e-02 GO:0003012 muscle system process
3.99 8.41e-05 GO:0007409 axonogenesis
3.96 1.47e-02 GO:0061061 muscle structure development
3.85 3.32e-09 GO:0007155 cell adhesion
3.85 3.32e-09 GO:0022610 biological adhesion
3.85 1.53e-04 GO:0048667 cell morphogenesis involved in neuron differentiation
3.81 5.64e-03 GO:0007411 axon guidance
3.79 2.05e-04 GO:0048812 neuron projection morphogenesis

Gene overrepresentation in compartment category:

Showing 1 to 9 of 9 entries
Enrichment   P-value GO Accession GO Term
21.94 4.78e-02 GO:0031258 lamellipodium membrane
10.16 2.06e-02 GO:0005581 collagen
7.31 7.93e-03 GO:0005604 basement membrane
7.12 7.05e-05 GO:0044420 extracellular matrix part
5.02 2.35e-07 GO:0005578 proteinaceous extracellular matrix
4.66 1.59e-07 GO:0031012 extracellular matrix
3.18 3.45e-09 GO:0044421 extracellular region part
2.65 6.36e-04 GO:0005615 extracellular space
2.26 1.58e-07 GO:0005576 extracellular region

Gene overrepresentation in function category:

Showing 1 to 5 of 5 entries
Enrichment   P-value GO Accession GO Term
54.83 2.18e-03 GO:0004157 dihydropyrimidinase activity
31.33 1.85e-02 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
8.00 5.67e-03 GO:0005178 integrin binding
2.57 1.14e-02 GO:0005509 calcium ion binding
2.38 1.40e-03 GO:0005102 receptor binding