Motif ID: HLF.p2

Z-value: 2.470


Transcription factors associated with HLF.p2:

Gene SymbolEntrez IDGene Name
HLF 3131 hepatic leukemia factor

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
HLFhg19_v1_chr17_+_53342320_53342344-0.067.4e-01Click!


Activity profile for motif HLF.p2.

activity profile for motif HLF.p2


Sorted Z-values histogram for motif HLF.p2

Sorted Z-values for motif HLF.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of HLF.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr5_-_39364562 26.894 NM_001737
C9
complement component 9
chr9_+_117085302 22.587 NM_000607
ORM1
orosomucoid 1
chr3_+_186435097 20.122 NM_000893
NM_001102416
NM_001166451
KNG1


kininogen 1


chr9_+_117092068 20.062 NM_000608
ORM2
orosomucoid 2
chr19_-_41356193 17.665 NM_000762
CYP2A6
cytochrome P450, family 2, subfamily A, polypeptide 6
chr4_+_155484131 17.196 NM_001184741
NM_005141
FGB

fibrinogen beta chain

chr16_+_72088507 16.280 NM_001126102
NM_005143
HP

haptoglobin

chr16_+_72097124 14.262 NM_020995
HPR
haptoglobin-related protein
chr3_+_186383770 14.186 NM_000412
HRG
histidine-rich glycoprotein
chr6_+_131894343 14.143 NM_000045
NM_001244438
ARG1

arginase, liver

chr19_+_41594367 13.097 NM_000766
CYP2A13
cytochrome P450, family 2, subfamily A, polypeptide 13
chr10_-_52645430 13.019 NM_001198818
NM_001198819
NM_001198820
NM_014576
NM_138932
NM_138933
A1CF





APOBEC1 complementation factor





chr14_-_70263871 12.094 NM_003049
SLC10A1
solute carrier family 10 (sodium/bile acid cotransporter family), member 1
chr19_+_35773409 11.380 NM_021175
HAMP
hepcidin antimicrobial peptide
chr2_-_88427535 10.831 NM_001443
FABP1
fatty acid binding protein 1, liver
chr11_-_116663106 10.729 NM_001166598
NM_052968
APOA5

apolipoprotein A-V

chr1_+_196857143 10.340 NM_001201550
NM_001201551
NM_006684
CFHR4


complement factor H-related 4


chr11_+_63057371 10.107 NM_001039752
SLC22A10
solute carrier family 22, member 10
chr3_+_186330844 10.094 NM_001622
AHSG
alpha-2-HS-glycoprotein
chr11_-_6462129 9.919 NM_000613
HPX
hemopexin
chr11_+_18287807 9.349 NM_000331
NM_001178006
NM_199161
SAA1


serum amyloid A1


chr19_+_49259343 9.311 NM_019113
FGF21
fibroblast growth factor 21
chr10_+_74653338 9.216 NM_152635
OIT3
oncoprotein induced transcript 3
chr3_+_119501556 8.894 NM_022002
NR1I2
nuclear receptor subfamily 1, group I, member 2
chr12_-_21757752 8.863 NM_021957
GYS2
glycogen synthase 2 (liver)
chr11_-_14993790 8.442 NM_001033952
NM_001033953
NM_001741
CALCA


calcitonin-related polypeptide alpha


chr4_+_187187342 8.420 F11
coagulation factor XI
chr1_-_230849936 8.349 AGT
angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
chr3_-_49726081 8.277 NM_020998
MST1
macrophage stimulating 1 (hepatocyte growth factor-like)
chr2_+_113885137 7.924 NM_173842
IL1RN
interleukin 1 receptor antagonist
chr3_+_133494275 7.874 TF
transferrin
chr3_-_120400957 7.674 HGD
homogentisate 1,2-dioxygenase
chr5_-_147211141 7.587 SPINK1
serine peptidase inhibitor, Kazal type 1
chr7_-_15601574 7.467 NM_001004320
AGMO
alkylglycerol monooxygenase
chr10_-_82049178 7.449 NM_000429
MAT1A
methionine adenosyltransferase I, alpha
chr2_-_31637598 7.428 NM_000379
XDH
xanthine dehydrogenase
chr13_-_46679143 7.366 NM_001872
NM_016413
CPB2

carboxypeptidase B2 (plasma)

chr11_-_18258383 7.234 NM_006512
SAA4
serum amyloid A4, constitutive
chr1_-_230849863 7.224 AGT
angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
chr3_+_186330859 7.194 AHSG
alpha-2-HS-glycoprotein
chr19_+_41430123 6.707 CYP2B7P1
cytochrome P450, family 2, subfamily B, polypeptide 7 pseudogene 1
chr3_-_58200397 6.673 NM_004944
DNASE1L3
deoxyribonuclease I-like 3
chr19_-_41388656 6.656 NM_000764
NM_030589
CYP2A7

cytochrome P450, family 2, subfamily A, polypeptide 7

chr2_+_113885145 6.612 IL1RN
interleukin 1 receptor antagonist
chr3_-_170744458 6.442 SLC2A2
solute carrier family 2 (facilitated glucose transporter), member 2
chr2_-_73869493 6.336 NM_003960
NAT8
N-acetyltransferase 8 (GCN5-related, putative)
chr8_+_120079423 6.325 NM_006438
COLEC10
collectin sub-family member 10 (C-type lectin)
chr15_+_58430394 6.196 NM_020980
AQP9
aquaporin 9
chr4_+_100485239 5.888 NM_000253
MTTP
microsomal triglyceride transfer protein
chr1_+_207262211 5.863 NM_001017365
NM_001017366
C4BPB

complement component 4 binding protein, beta

chr1_-_230849847 5.764 AGT
angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
chr10_-_95360959 5.625 NM_006744
RBP4
retinol binding protein 4, plasma
chr2_-_31637553 5.614 XDH
xanthine dehydrogenase
chr10_+_5238756 5.528 NM_001818
AKR1C4
aldo-keto reductase family 1, member C4 (chlordecone reductase; 3-alpha hydroxysteroid dehydrogenase, type I; dihydrodiol dehydrogenase 4)
chr16_-_55866972 5.351 CES1
carboxylesterase 1
chr12_+_16500075 5.324 NM_145792
MGST1
microsomal glutathione S-transferase 1
chr9_+_111624545 5.287 NM_006687
ACTL7A
actin-like 7A
chr16_-_55867016 5.204 NM_001025194
NM_001025195
NM_001266
CES1


carboxylesterase 1


chr17_-_17485744 5.065 NM_007169
PEMT
phosphatidylethanolamine N-methyltransferase
chr4_+_74269971 5.014 NM_000477
ALB
albumin
chr5_-_147211235 4.869 NM_003122
SPINK1
serine peptidase inhibitor, Kazal type 1
chr3_-_190580464 4.662 NM_001146686
GMNC
geminin coiled-coil domain containing
chr12_-_105322056 4.614 NM_032148
SLC41A2
solute carrier family 41, member 2
chr17_-_17485691 4.549 PEMT
phosphatidylethanolamine N-methyltransferase
chr1_+_196946666 4.278 NM_030787
CFHR5
complement factor H-related 5
chr10_-_104597079 4.097 NM_000102
CYP17A1
cytochrome P450, family 17, subfamily A, polypeptide 1
chr4_-_185747183 4.094 NM_001995
ACSL1
acyl-CoA synthetase long-chain family member 1
chr3_+_186330711 4.082 AHSG
alpha-2-HS-glycoprotein
chr3_-_170744529 4.048 SLC2A2
solute carrier family 2 (facilitated glucose transporter), member 2
chr11_-_18270167 3.974 NM_001199744
NM_001127380
NM_030754
SAA2-SAA4
SAA2

SAA2-SAA4 readthrough
serum amyloid A2

chr5_-_140012730 3.963 CD14
CD14 molecule
chr17_-_34329083 3.944 NM_032965
CCL15
chemokine (C-C motif) ligand 15
chr9_-_104198045 3.894 NM_000035
ALDOB
aldolase B, fructose-bisphosphate
chr6_-_133035180 3.854 NM_004666
VNN1
vanin 1
chr8_+_24298442 3.850 NM_003817
ADAM7
ADAM metallopeptidase domain 7
chr17_-_64225496 3.798 NM_000042
APOH
apolipoprotein H (beta-2-glycoprotein I)
chr12_-_88423145 3.685 NM_152589
C12orf50
chromosome 12 open reading frame 50
chr5_-_140013034 3.619 NM_000591
CD14
CD14 molecule
chr8_-_6735438 3.614 NM_005218
DEFB1
defensin, beta 1
chr6_+_31895201 3.573 NM_000063
NM_001145903
C2

complement component 2

chr11_+_69061599 3.519 NM_138768
MYEOV
myeloma overexpressed (in a subset of t(11;14) positive multiple myelomas)
chr7_+_129847699 3.424 NM_145268
C7orf45
chromosome 7 open reading frame 45
chr4_+_71200670 3.337 NM_033122
CABS1
calcium-binding protein, spermatid-specific 1
chr1_+_241695433 3.332 NM_003679
KMO
kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
chr4_+_69962191 3.313 NM_001074
UGT2B7
UDP glucuronosyltransferase 2 family, polypeptide B7
chr22_+_24979717 3.303 NM_013430
GGT1
gamma-glutamyltransferase 1
chr14_+_24563369 3.223 NM_001018073
NM_004563
PCK2

phosphoenolpyruvate carboxykinase 2 (mitochondrial)

chr1_-_207143944 3.220 NM_001122979
NM_001170631
NM_032029
FCAMR


Fc receptor, IgA, IgM, high affinity


chr1_+_154377847 3.169 IL6R
interleukin 6 receptor
chr9_-_19033183 3.168 NM_153707
FAM154A
family with sequence similarity 154, member A
chr19_-_8809054 3.144 NM_178525
ACTL9
actin-like 9
chr20_+_55099784 3.118 NM_001012971
FAM209A
FAM209B
family with sequence similarity 209, member A
family with sequence similarity 209, member B
chr2_-_169887832 3.085 NM_003742
ABCB11
ATP-binding cassette, sub-family B (MDR/TAP), member 11
chr6_+_31895401 3.000 C2
complement component 2
chr4_+_39408472 2.967 NM_175737
KLB
klotho beta
chr11_-_66675334 2.946 NM_022172
PC
pyruvate carboxylase
chr8_-_145115565 2.940 NM_017570
OPLAH
5-oxoprolinase (ATP-hydrolysing)
chr14_+_103388992 2.932 NM_030943
AMN
amnionless homolog (mouse)
chr12_-_4754275 2.815 NM_006422
AKAP3
A kinase (PRKA) anchor protein 3
chr1_+_196621007 2.783 NM_000186
NM_001014975
CFH

complement factor H

chr19_-_4540035 2.745 NM_052972
LRG1
leucine-rich alpha-2-glycoprotein 1
chr14_-_23284617 2.725 SLC7A7
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr22_+_25003610 2.620 NM_001032365
GGT1
gamma-glutamyltransferase 1
chr10_+_64893003 2.586 NM_030759
NRBF2
nuclear receptor binding factor 2
chr6_-_24489738 2.586 NM_177483
NM_001503
GPLD1

glycosylphosphatidylinositol specific phospholipase D1

chr6_+_131148544 2.583 NM_001195597
LOC100507203
uncharacterized LOC100507203
chr19_+_45417920 2.517 NM_001645
APOC1
apolipoprotein C-I
chr4_-_170924911 2.498 NM_001009554
MFAP3L
microfibrillar-associated protein 3-like
chr9_+_103947316 2.482 NM_017753
LPPR1
lipid phosphate phosphatase-related protein type 1
chr4_-_185747051 2.477 ACSL1
acyl-CoA synthetase long-chain family member 1
chr8_+_10383055 2.470 NM_001197020
NM_198464
PRSS55

protease, serine, 55

chr1_+_209878135 2.455 NM_005525
HSD11B1
hydroxysteroid (11-beta) dehydrogenase 1
chr20_+_23471765 2.397 NM_005492
CST8
cystatin 8 (cystatin-related epididymal specific)
chr7_+_45933096 2.391


chr19_-_4540078 2.373 LRG1
leucine-rich alpha-2-glycoprotein 1
chr14_-_23284565 2.346 SLC7A7
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr1_+_57320442 2.312 NM_000562
C8A
complement component 8, alpha polypeptide
chr17_-_34328530 2.288 CCL14-CCL15
CCL15
CCL14-CCL15 readthrough
chemokine (C-C motif) ligand 15
chr19_-_46088084 2.279 NM_001017989
NM_025136
OPA3

optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)

chr1_+_110655061 2.213 NM_203412
UBL4B
ubiquitin-like 4B
chr1_-_162346579 2.179 NM_182581
C1orf111
chromosome 1 open reading frame 111
chr1_-_230850335 2.100 NM_000029
AGT
angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
chr12_+_16064105 2.078 NM_015954
DERA
deoxyribose-phosphate aldolase (putative)
chr12_-_13256572 2.076 NM_001080554
NM_001080555
NM_001206842
GSG1


germ cell associated 1


chr9_-_91267004 2.075 NM_001100111
LOC286238
uncharacterized LOC286238
chr10_-_101190201 2.023 NM_002079
GOT1
glutamic-oxaloacetic transaminase 1, soluble (aspartate aminotransferase 1)
chr11_+_112047088 2.012 NM_001037290
BCO2
beta-carotene oxygenase 2
chr19_+_45418063 2.012 APOC1
apolipoprotein C-I
chr1_-_153123426 2.010 NM_001014291
SPRR2G
small proline-rich protein 2G
chr16_+_68057144 2.003 NM_017803
DUS2L
dihydrouridine synthase 2-like, SMM1 homolog (S. cerevisiae)
chr17_-_39324423 1.975 NM_033187
KRTAP4-3
keratin associated protein 4-3
chr3_+_148447966 1.952 NM_032049
AGTR1
angiotensin II receptor, type 1
chr15_-_83621350 1.914 NM_004839
NM_199330
HOMER2

homer homolog 2 (Drosophila)

chr15_+_91411884 1.895 NM_002569
FURIN
furin (paired basic amino acid cleaving enzyme)
chr7_+_128349111 1.888 FAM71F1
family with sequence similarity 71, member F1
chr12_+_16064232 1.874 DERA
deoxyribose-phosphate aldolase (putative)
chr11_+_112046207 1.859 NM_031938
BCO2
beta-carotene oxygenase 2
chr20_+_42187634 1.859 NM_170693
SGK2
serum/glucocorticoid regulated kinase 2
chr12_+_57623355 1.830 NM_001166356
NM_005412
SHMT2

serine hydroxymethyltransferase 2 (mitochondrial)

chr5_+_42548314 1.830 NM_001242403
GHR
growth hormone receptor
chr1_-_204121144 1.827 NM_018208
ETNK2
ethanolamine kinase 2
chr12_+_16064282 1.820 DERA
deoxyribose-phosphate aldolase (putative)
chr8_+_40010986 1.809 NM_020130
C8orf4
chromosome 8 open reading frame 4
chr5_+_42425093 1.798 NM_001242401
GHR
growth hormone receptor
chr17_-_41277409 1.795 NM_007297
NM_007299
NM_007294
NM_007300
BRCA1



breast cancer 1, early onset



chr17_+_685512 1.771 NM_018146
RNMTL1
RNA methyltransferase like 1
chr4_+_74702272 1.762 NM_002993
CXCL6
chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2)
chr1_+_196788860 1.748 NM_002113
CFHR1
complement factor H-related 1
chr1_+_152850797 1.747 NM_030663
SMCP
sperm mitochondria-associated cysteine-rich protein
chr19_-_46088021 1.741 OPA3
optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
chr1_+_151739130 1.739 NM_016178
OAZ3
ornithine decarboxylase antizyme 3
chr4_-_100485173 1.728 NM_001134665
NM_001134666
RG9MTD2

RNA (guanine-9-) methyltransferase domain containing 2

chrY_+_3447081 1.728 NM_139214
TGIF2LY
TGFB-induced factor homeobox 2-like, Y-linked
chr17_-_34328607 1.705 CCL14-CCL15
CCL14-CCL15 readthrough
chr2_-_21228189 1.698 APOB
apolipoprotein B (including Ag(x) antigen)
chr20_+_30028410 1.672 NM_153324
DEFB123
defensin, beta 123
chr13_-_60325073 1.667


chr9_-_107666046 1.660 ABCA1
ATP-binding cassette, sub-family A (ABC1), member 1
chr1_+_192127591 1.660 NM_130782
RGS18
regulator of G-protein signaling 18
chr14_+_21423627 1.659 NM_002934
RNASE2
ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin)
chr1_+_112016588 1.640 NM_174896
C1orf162
chromosome 1 open reading frame 162
chr18_+_54814292 1.636 BOD1P
biorientation of chromosomes in cell division 1 pseudogene
chr3_-_195938256 1.628 NM_001039617
ZDHHC19
zinc finger, DHHC-type containing 19
chr16_-_68057098 1.623 DDX28
DEAD (Asp-Glu-Ala-Asp) box polypeptide 28
chr4_+_118955499 1.612 NM_004784
NDST3
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3
chr17_+_51900238 1.609 NM_032559
KIF2B
kinesin family member 2B
chr2_+_3705785 1.600 NM_018436
ALLC
allantoicase
chr2_-_27362277 1.593 NM_178553
C2orf53
chromosome 2 open reading frame 53
chr1_-_204183036 1.584 NM_198447
GOLT1A
golgi transport 1A
chr9_+_105757592 1.582 NM_001340
CYLC2
cylicin, basic protein of sperm head cytoskeleton 2
chr4_-_23891608 1.581 NM_013261
PPARGC1A
peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
chr6_-_132032156 1.570 NM_001145659
CTAGE9
CTAGE family, member 9
chr2_+_211421322 1.562 NM_001875
CPS1
carbamoyl-phosphate synthase 1, mitochondrial
chr7_+_143880547 1.536 NM_198495
CTAGE4
CTAGE8
CTAGE family, member 4
CTAGE family, member 8
chr1_+_209859524 1.535 NM_001206741
NM_181755
HSD11B1

hydroxysteroid (11-beta) dehydrogenase 1

chr2_-_234652623 1.510 NM_001001394
DNAJB3
DnaJ (Hsp40) homolog, subfamily B, member 3
chr6_+_150690027 1.508 NM_001164694
NM_001164695
NM_203395
IYD


iodotyrosine deiodinase


chr19_-_46088074 1.502 OPA3
optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
chr10_+_89267589 1.492 NM_001178118
MINPP1
multiple inositol-polyphosphate phosphatase 1
chr12_+_57623827 1.474 NM_001166358
NM_001166359
NM_001166357
SHMT2


serine hydroxymethyltransferase 2 (mitochondrial)


chr1_+_186265404 1.465 NM_001127708
NM_001127709
NM_001127710
NM_005807
PRG4



proteoglycan 4



chr1_-_204120909 1.447 ETNK2
ethanolamine kinase 2
chr9_+_110045516 1.446 NM_002874
RAD23B
RAD23 homolog B (S. cerevisiae)
chr7_-_122342965 1.443 NM_198085
RNF148
ring finger protein 148
chr6_-_161087406 1.442 NM_005577
LPA
lipoprotein, Lp(a)
chr12_-_7261788 1.428 NM_016546
C1RL
complement component 1, r subcomponent-like
chr16_-_30457197 1.420 NM_012248
SEPHS2
selenophosphate synthetase 2
chr3_+_142342265 1.419 NM_002670
PLS1
plastin 1
chr5_-_147162251 1.407 NM_014790
JAKMIP2
janus kinase and microtubule interacting protein 2
chr16_-_20911560 1.394 NM_173475
DCUN1D3
DCN1, defective in cullin neddylation 1, domain containing 3 (S. cerevisiae)
chrY_-_15591799 1.391 UTY
ubiquitously transcribed tetratricopeptide repeat gene, Y-linked
chr16_-_68057120 1.381 DDX28
DEAD (Asp-Glu-Ala-Asp) box polypeptide 28
chr20_-_1600589 1.375 NM_001083910
NM_001135844
NM_006065
SIRPB1


signal-regulatory protein beta 1


chr2_+_232457574 1.367 NM_152614
C2orf57
chromosome 2 open reading frame 57
chr1_-_203155910 1.366 NM_001276
CHI3L1
chitinase 3-like 1 (cartilage glycoprotein-39)
chr9_-_104145800 1.354 NM_001127610
BAAT
bile acid CoA: amino acid N-acyltransferase (glycine N-choloyltransferase)
chr17_-_39274587 1.348 NM_033059
KRTAP4-11
keratin associated protein 4-11
chr11_-_68039327 1.347 C11orf24
chromosome 11 open reading frame 24
chr20_+_42187705 1.346 SGK2
serum/glucocorticoid regulated kinase 2
chr7_+_142636602 1.340 NM_178829
C7orf34
chromosome 7 open reading frame 34

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
16.92 3.23e-08 GO:0072376 protein activation cascade
3.60 8.62e-08 GO:0006629 lipid metabolic process
3.90 2.14e-06 GO:0019752 carboxylic acid metabolic process
3.90 2.14e-06 GO:0043436 oxoacid metabolic process
3.81 3.40e-06 GO:0042180 cellular ketone metabolic process
3.80 3.51e-06 GO:0006082 organic acid metabolic process
17.88 1.05e-05 GO:0006956 complement activation
13.90 8.32e-05 GO:0002526 acute inflammatory response
17.75 9.40e-05 GO:0006953 acute-phase response
3.12 1.10e-04 GO:0009611 response to wounding
12.95 1.48e-04 GO:0019217 regulation of fatty acid metabolic process
21.66 2.26e-04 GO:0071825 protein-lipid complex subunit organization
21.66 2.26e-04 GO:0071827 plasma lipoprotein particle organization
9.94 2.52e-04 GO:0042157 lipoprotein metabolic process
29.32 4.53e-04 GO:0015721 bile acid and bile salt transport
6.09 5.79e-04 GO:0046486 glycerolipid metabolic process
2.26 6.96e-04 GO:0044281 small molecule metabolic process
3.05 8.70e-04 GO:0006952 defense response
4.05 8.94e-04 GO:0071702 organic substance transport
4.46 1.24e-03 GO:0006520 cellular amino acid metabolic process
16.09 1.47e-03 GO:0097006 regulation of plasma lipoprotein particle levels
6.90 1.65e-03 GO:0019216 regulation of lipid metabolic process
11.73 1.79e-03 GO:0045834 positive regulation of lipid metabolic process
9.39 1.84e-03 GO:0006959 humoral immune response
37.53 2.21e-03 GO:0006107 oxaloacetate metabolic process
21.33 2.59e-03 GO:0034367 macromolecular complex remodeling
21.33 2.59e-03 GO:0034368 protein-lipid complex remodeling
21.33 2.59e-03 GO:0034369 plasma lipoprotein particle remodeling
7.54 2.64e-03 GO:0006575 cellular modified amino acid metabolic process
3.92 2.87e-03 GO:0044106 cellular amine metabolic process
6.43 3.14e-03 GO:0006869 lipid transport
14.08 3.33e-03 GO:0006094 gluconeogenesis
5.15 3.41e-03 GO:0008202 steroid metabolic process
19.55 4.11e-03 GO:0045923 positive regulation of fatty acid metabolic process
4.59 4.69e-03 GO:0006954 inflammatory response
1.95 4.85e-03 GO:0006950 response to stress
3.14 5.01e-03 GO:0044255 cellular lipid metabolic process
7.99 6.22e-03 GO:0006662 glycerol ether metabolic process
7.91 6.73e-03 GO:0018904 organic ether metabolic process
5.91 6.73e-03 GO:0010876 lipid localization
3.49 6.76e-03 GO:0009308 amine metabolic process
28.87 7.33e-03 GO:0006957 complement activation, alternative pathway
9.52 7.41e-03 GO:0006641 triglyceride metabolic process
1.99 7.94e-03 GO:0065008 regulation of biological quality
6.35 1.08e-02 GO:0010565 regulation of cellular ketone metabolic process
11.49 1.12e-02 GO:0019319 hexose biosynthetic process
8.88 1.18e-02 GO:0006638 neutral lipid metabolic process
8.88 1.18e-02 GO:0006639 acylglycerol metabolic process
15.14 1.55e-02 GO:0006958 complement activation, classical pathway
5.95 1.83e-02 GO:0002252 immune effector process
3.35 2.09e-02 GO:0007596 blood coagulation
3.35 2.09e-02 GO:0050817 coagulation
3.33 2.27e-02 GO:0007599 hemostasis
22.08 2.36e-02 GO:0031640 killing of cells of other organism
3.03 2.46e-02 GO:0048878 chemical homeostasis
3.29 2.59e-02 GO:0044283 small molecule biosynthetic process
13.41 2.86e-02 GO:0002455 humoral immune response mediated by circulating immunoglobulin
3.10 3.12e-02 GO:0050878 regulation of body fluid levels
40.21 3.61e-02 GO:0010873 positive regulation of cholesterol esterification
9.39 3.65e-02 GO:0046364 monosaccharide biosynthetic process
7.47 3.69e-02 GO:0034637 cellular carbohydrate biosynthetic process
12.68 3.78e-02 GO:0008206 bile acid metabolic process
9.08 4.40e-02 GO:0015718 monocarboxylic acid transport
8.94 4.82e-02 GO:0046890 regulation of lipid biosynthetic process
2.99 4.90e-02 GO:0042060 wound healing
12.03 4.90e-02 GO:0030193 regulation of blood coagulation

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
4.16 3.03e-10 GO:0005615 extracellular space
2.66 7.19e-10 GO:0005576 extracellular region
3.30 7.23e-08 GO:0044421 extracellular region part
21.45 3.74e-07 GO:0032994 protein-lipid complex
21.45 3.74e-07 GO:0034358 plasma lipoprotein particle
23.46 2.25e-05 GO:0034364 high-density lipoprotein particle
31.28 8.56e-04 GO:0042627 chylomicron
10.83 2.66e-03 GO:0031983 vesicle lumen
18.77 7.84e-03 GO:0034361 very-low-density lipoprotein particle
18.77 7.84e-03 GO:0034385 triglyceride-rich lipoprotein particle
9.99 2.04e-02 GO:0031093 platelet alpha granule lumen
9.78 2.26e-02 GO:0034774 secretory granule lumen
9.39 2.75e-02 GO:0060205 cytoplasmic membrane-bounded vesicle lumen

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
8.46 5.68e-05 GO:0008201 heparin binding
7.03 9.42e-05 GO:0005539 glycosaminoglycan binding
6.50 2.06e-04 GO:0001871 pattern binding
6.50 2.06e-04 GO:0030247 polysaccharide binding
5.24 1.65e-03 GO:0005543 phospholipid binding
3.60 7.06e-03 GO:0030246 carbohydrate binding
40.21 8.16e-03 GO:0031210 phosphatidylcholine binding
35.19 1.30e-02 GO:0016832 aldehyde-lyase activity
10.67 2.00e-02 GO:0016830 carbon-carbon lyase activity
93.82 2.30e-02 GO:0008389 coumarin 7-hydroxylase activity
93.82 2.30e-02 GO:0010698 acetyltransferase activator activity
28.15 2.73e-02 GO:0050997 quaternary ammonium group binding
3.16 2.93e-02 GO:0008289 lipid binding
5.22 3.04e-02 GO:0004252 serine-type endopeptidase activity
5.15 3.34e-02 GO:0004866 endopeptidase inhibitor activity
7.04 4.16e-02 GO:0004497 monooxygenase activity
4.94 4.41e-02 GO:0061135 endopeptidase regulator activity
4.88 4.82e-02 GO:0030414 peptidase inhibitor activity