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Motif ID: HNF1A.p2

Z-value: 10.540

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr4_-_72649734	161.545	NM_000583	GC	group-specific component (vitamin D binding protein)
chr1_-_159684274	158.324	NM_000567	CRP	C-reactive protein, pentraxin-related
chr4_+_74347461	145.745	NM_001133	AFM	afamin
chr4_-_155511838	131.965	NM_000508 NM_021871	FGA	fibrinogen alpha chain
chr4_+_155484131	129.741	NM_001184741 NM_005141	FGB	fibrinogen beta chain
chr17_-_64225496	119.840	NM_000042	APOH	apolipoprotein H (beta-2-glycoprotein I)
chr4_+_74269971	115.688	NM_000477	ALB	albumin
chr1_+_159557615	106.774	NM_001639	APCS	amyloid P component, serum
chr17_+_41052813	95.277	NM_000151	G6PC	glucose-6-phosphatase, catalytic subunit
chr2_+_234668914	93.719	NM_000463	UGT1A1	UDP glucuronosyltransferase 1 family, polypeptide A1
chr5_-_147211141	91.777		SPINK1	serine peptidase inhibitor, Kazal type 1
chr2_+_234601511	89.928	NM_001072	UGT1A6	UDP glucuronosyltransferase 1 family, polypeptide A6
chr19_-_36303766	89.070		PRODH2	proline dehydrogenase (oxidase) 2
chrX_-_105282714	88.849	NM_000354	SERPINA7	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7
chr5_-_147211235	88.367	NM_003122	SPINK1	serine peptidase inhibitor, Kazal type 1
chr8_-_17752847	88.288	NM_147203 NM_201553 NM_004467 NM_201552	FGL1	fibrinogen-like 1
chr14_-_94854910	86.867		SERPINA1	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chr6_+_161123224	86.262	NM_000301 NM_001168338	PLG	plasminogen
chr14_-_94789641	82.717	NM_001756	SERPINA6	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6
chr14_-_94855120	81.964	NM_000295	SERPINA1	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chr20_+_43029865	81.254	NM_000457 NM_178849 NM_178850	HNF4A	hepatocyte nuclear factor 4, alpha
chr19_-_36303724	78.575		PRODH2	proline dehydrogenase (oxidase) 2
chr1_+_119911395	77.735	NM_001005783 NM_016527	HAO2	hydroxyacid oxidase 2 (long chain)
chr2_+_234526290	76.621	NM_019076	UGT1A8	UDP glucuronosyltransferase 1 family, polypeptide A8
chr14_+_95027760	76.456	NM_006215	SERPINA4	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4
chr12_+_21284127	73.205	NM_006446	SLCO1B1	solute carrier organic anion transporter family, member 1B1
chr1_-_197036350	71.328	NM_001994	F13B	coagulation factor XIII, B polypeptide
chr14_-_57960432	70.934	NM_018168	C14orf105	chromosome 14 open reading frame 105
chr20_-_7921068	70.369	NM_017545	HAO1	hydroxyacid oxidase (glycolate oxidase) 1
chr2_+_234627423	69.508	NM_007120	UGT1A4	UDP glucuronosyltransferase 1 family, polypeptide A4
chr14_-_94759594	66.478	NM_001100607	SERPINA10	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10
chr4_-_69817478	65.644	NM_024743	UGT2A3	UDP glucuronosyltransferase 2 family, polypeptide A3
chr11_+_46740769	65.339		F2	coagulation factor II (thrombin)
chr2_-_88427535	64.243	NM_001443	FABP1	fatty acid binding protein 1, liver
chr1_-_204183036	63.425	NM_198447	GOLT1A	golgi transport 1A
chr5_-_135290521	62.367	NM_002302	LECT2	leukocyte cell-derived chemotaxin 2
chr10_+_135340865	62.354	NM_000773	CYP2E1	cytochrome P450, family 2, subfamily E, polypeptide 1
chr3_+_186383770	61.623	NM_000412	HRG	histidine-rich glycoprotein
chr14_-_94759556	61.062		SERPINA10	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10
chr19_-_48389514	61.027		SULT2A1	sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1
chr15_+_58724174	60.040	NM_000236	LIPC	lipase, hepatic
chr10_+_115312777	59.070	NM_004132	HABP2	hyaluronan binding protein 2
chr20_+_43030005	58.495		HNF4A	hepatocyte nuclear factor 4, alpha
chr4_-_69434215	58.311	NM_001077	UGT2B15 UGT2B17	UDP glucuronosyltransferase 2 family, polypeptide B15 UDP glucuronosyltransferase 2 family, polypeptide B17
chr14_-_94759360	57.949	NM_016186	SERPINA10	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10
chr19_+_41509825	57.313		CYP2B6	cytochrome P450, family 2, subfamily B, polypeptide 6
chr1_+_207277577	57.048	NM_000715	C4BPA	complement component 4 binding protein, alpha
chr11_+_46740736	56.962	NM_000506	F2	coagulation factor II (thrombin)
chr19_-_48389571	56.346	NM_003167	SULT2A1	sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1
chr20_+_42984088	56.174		HNF4A	hepatocyte nuclear factor 4, alpha
chr19_-_36304200	55.986	NM_021232	PRODH2	proline dehydrogenase (oxidase) 2
chr4_+_187187117	55.903	NM_000128	F11	coagulation factor XI
chr10_-_52645430	55.481	NM_001198818 NM_001198819 NM_001198820 NM_014576 NM_138932 NM_138933	A1CF	APOBEC1 complementation factor
chr20_+_43029936	55.199		HNF4A	hepatocyte nuclear factor 4, alpha
chr11_-_117695408	54.876	NM_001680	FXYD2	FXYD domain containing ion transport regulator 2
chrX_+_70435087	54.397		GJB1	gap junction protein, beta 1, 32kDa
chr12_+_20963637	54.235	NM_019844	SLCO1B3	solute carrier organic anion transporter family, member 1B3
chr20_+_42984338	51.862	NM_001030003 NM_001030004 NM_175914	HNF4A	hepatocyte nuclear factor 4, alpha
chr4_+_69962191	50.054	NM_001074	UGT2B7	UDP glucuronosyltransferase 2 family, polypeptide B7
chr7_+_45927958	49.911	NM_000596	IGFBP1	insulin-like growth factor binding protein 1
chr17_+_4692226	49.683	NM_001014985	GLTPD2	glycolipid transfer protein domain containing 2
chr17_+_1646129	48.890	NM_000934 NM_001165921	SERPINF2	serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2
chrX_+_70435048	48.629	NM_001097642	GJB1	gap junction protein, beta 1, 32kDa
chr20_+_42187705	48.386		SGK2	serum/glucocorticoid regulated kinase 2
chr7_-_50633042	47.706	NM_001082971	DDC	dopa decarboxylase (aromatic L-amino acid decarboxylase)
chr6_+_31623688	47.200		APOM	apolipoprotein M
chr6_+_31623668	45.872	NM_019101	APOM	apolipoprotein M
chr20_+_43029973	45.528		HNF4A	hepatocyte nuclear factor 4, alpha
chr16_+_21245015	45.259	NM_145865	ANKS4B	ankyrin repeat and sterile alpha motif domain containing 4B
chr2_+_234637772	44.719	NM_019093	UGT1A3	UDP glucuronosyltransferase 1 family, polypeptide A3
chr9_-_123812535	44.573	NM_001735	C5	complement component 5
chr4_-_110723127	44.384		CFI	complement factor I
chr7_-_44580857	44.210	NM_001101648 NM_013389	NPC1L1	NPC1 (Niemann-Pick disease, type C1, gene)-like 1
chr10_+_99344421	43.213		HOGA1	4-hydroxy-2-oxoglutarate aldolase 1
chr14_+_39703119	42.377	NM_054024	MIA2	melanoma inhibitory activity 2
chr2_+_88047603	42.170	NM_002665 NM_001032392	PLGLB2 PLGLB1	plasminogen-like B2 plasminogen-like B1
chr10_+_101542460	42.105	NM_000392	ABCC2	ATP-binding cassette, sub-family C (CFTR/MRP), member 2
chr19_+_11350282	41.450	NM_018687	C19orf80	chromosome 19 open reading frame 80
chr3_+_149192367	40.344	NM_004617	TM4SF4	transmembrane 4 L six family member 4
chr20_+_42187634	39.939	NM_170693	SGK2	serum/glucocorticoid regulated kinase 2
chr17_+_1646143	39.601		SERPINF2	serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2
chrX_-_15683153	38.694	NM_020665	TMEM27	transmembrane protein 27
chr18_+_29171729	38.455	NM_000371	TTR	transthyretin
chr3_+_149192479	37.816		TM4SF4	transmembrane 4 L six family member 4
chr11_+_46740759	37.719		F2	coagulation factor II (thrombin)
chr19_-_58864820	36.944	NM_130786	A1BG	alpha-1-B glycoprotein
chr14_+_21156922	36.708	NM_001097577 NM_194431	ANG RNASE4	angiogenin, ribonuclease, RNase A family, 5 ribonuclease, RNase A family, 4
chr2_-_87248942	36.641	NM_002665 NM_001032392	PLGLB2 PLGLB1	plasminogen-like B2 plasminogen-like B1
chr10_-_70066594	36.529		PBLD	phenazine biosynthesis-like protein domain containing
chr6_-_25874439	36.084	NM_001098486 NM_006632	SLC17A3	solute carrier family 17 (sodium phosphate), member 3
chr2_+_234580504	36.020	NM_021027	UGT1A9	UDP glucuronosyltransferase 1 family, polypeptide A9
chr10_-_52645384	34.214		A1CF	APOBEC1 complementation factor
chr4_-_110723334	34.152	NM_000204	CFI	complement factor I
chr6_-_25930838	33.452	NM_005835	SLC17A2	solute carrier family 17 (sodium phosphate), member 2
chr2_+_27719702	32.791	NM_001486	GCKR	glucokinase (hexokinase 4) regulator
chr5_+_175976342	32.223	NM_017675	CDHR2	cadherin-related family member 2
chr4_+_187187342	32.134		F11	coagulation factor XI
chr4_+_169013687	31.741	NM_007193	ANXA10	annexin A10
chr6_+_25754926	31.733	NM_005495	SLC17A4	solute carrier family 17 (sodium phosphate), member 4
chr4_+_3443691	30.788	NM_001528	HGFAC	HGF activator
chr10_+_101542554	30.391		ABCC2	ATP-binding cassette, sub-family C (CFTR/MRP), member 2
chr17_+_1646290	28.989	NM_001165920	SERPINF2	serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2
chr16_-_20364029	28.947	NM_001008389 NM_003361	UMOD	uromodulin
chr16_-_69385656	28.935	NM_144676	TMED6	transmembrane emp24 protein transport domain containing 6
chr12_+_56624500	28.680	NM_001135195	SLC39A5	solute carrier family 39 (metal ion transporter), member 5
chr10_+_99344079	28.546	NM_001134670 NM_138413	HOGA1	4-hydroxy-2-oxoglutarate aldolase 1
chr2_+_234621637	28.460	NM_019078	UGT1A5	UDP glucuronosyltransferase 1 family, polypeptide A5
chr5_-_138718941	28.426		SLC23A1	solute carrier family 23 (nucleobase transporters), member 1
chr16_-_87970107	27.383	NM_001739	CA5A	carbonic anhydrase VA, mitochondrial
chr17_+_73642645	27.252	NM_001162997	C17orf110	chromosome 17 open reading frame 110
chr4_+_3443659	26.835		HGFAC	HGF activator
chr1_+_18807423	25.954	NM_152375	KLHDC7A	kelch domain containing 7A
chr15_-_90349819	25.848		ANPEP	alanyl (membrane) aminopeptidase
chr8_+_76320106	25.314		HNF4G	hepatocyte nuclear factor 4, gamma
chr8_-_124749573	24.974	NM_001003954 NM_004306	ANXA13	annexin A13
chr15_+_48498497	24.097	NM_000338 NM_001184832	SLC12A1	solute carrier family 12 (sodium/potassium/chloride transporters), member 1
chr11_+_64323089	23.089	NM_018484	SLC22A11	solute carrier family 22 (organic anion/urate transporter), member 11
chr19_-_33360641	22.835	NM_001126335 NM_001243036 NM_014270	SLC7A9	solute carrier family 7 (glycoprotein-associated amino acid transporter light chain, bo,+ system), member 9
chr6_-_116381765	21.689	NM_002031	FRK	fyn-related kinase
chr11_+_114167168	21.680		NNMT	nicotinamide N-methyltransferase
chr15_+_58430394	21.531	NM_020980	AQP9	aquaporin 9
chr1_+_207262211	21.293	NM_001017365 NM_001017366	C4BPB	complement component 4 binding protein, beta
chr16_-_48269087	20.966	NM_032583 NM_145186	ABCC11	ATP-binding cassette, sub-family C (CFTR/MRP), member 11
chr12_-_113841654	20.948	NM_006843	SDS	serine dehydratase
chr6_-_51952368	20.386	NM_138694 NM_170724	PKHD1	polycystic kidney and hepatic disease 1 (autosomal recessive)
chr9_-_116861336	19.552	NM_138424	KIF12	kinesin family member 12
chr6_-_24383519	19.375	NM_001195610	DCDC2	doublecortin domain containing 2
chr10_+_5136613	19.039		AKR1C3	aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)
chr1_-_20141593	18.570	NM_019062	RNF186	ring finger protein 186
chr10_+_5136589	18.399		AKR1C3	aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)
chr9_-_116861506	18.229		KIF12	kinesin family member 12
chr17_+_73553883	17.894		LLGL2	lethal giant larvae homolog 2 (Drosophila)
chr4_-_69536314	17.513	NM_001076	UGT2B15	UDP glucuronosyltransferase 2 family, polypeptide B15
chr1_+_162351519	17.454	NM_001085375	C1orf226	chromosome 1 open reading frame 226
chr5_-_138719018	16.987	NM_005847 NM_152685	SLC23A1	solute carrier family 23 (nucleobase transporters), member 1
chr10_+_5136556	16.948	NM_003739	AKR1C3	aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)
chr6_+_131894343	16.636	NM_000045 NM_001244438	ARG1	arginase, liver
chr3_+_190105660	16.341	NM_006580	CLDN16	claudin 16
chr6_-_52628272	15.668	NM_000846	GSTA2	glutathione S-transferase alpha 2
chr14_+_68168602	15.312	NM_152443	RDH12	retinol dehydrogenase 12 (all-trans/9-cis/11-cis)
chr4_-_70080448	14.990	NM_001073	UGT2B11 UGT2B10	UDP glucuronosyltransferase 2 family, polypeptide B11 UDP glucuronosyltransferase 2 family, polypeptide B10
chr10_-_129691202	14.825	NM_152311	CLRN3	clarin 3
chr11_+_561449	14.771	NM_001143994 NM_003475	RASSF7	Ras association (RalGDS/AF-6) domain family (N-terminal) member 7
chr3_+_119499330	14.467	NM_003889 NM_033013	NR1I2	nuclear receptor subfamily 1, group I, member 2
chr4_+_74270832	14.268		ALB	albumin
chr11_-_26743545	13.919	NM_178498	SLC5A12	solute carrier family 5 (sodium/glucose cotransporter), member 12
chr6_+_54173202	13.809	NM_014464	TINAG	tubulointerstitial nephritis antigen
chr4_-_100273831	13.683	NM_000669	ADH1C	alcohol dehydrogenase 1C (class I), gamma polypeptide
chr12_+_10331556	13.363	NM_153022	C12orf59	chromosome 12 open reading frame 59
chr18_-_48346297	13.245	NM_001127175 NM_001127176 NM_031939	MRO	maestro
chr1_-_47407094	13.215		CYP4A11	cytochrome P450, family 4, subfamily A, polypeptide 11
chr4_-_100212085	13.192	NM_000667	ADH1A	alcohol dehydrogenase 1A (class I), alpha polypeptide
chr6_+_167704802	13.169	NM_001143947 NM_018974	UNC93A	unc-93 homolog A (C. elegans)
chr11_+_114167197	12.814		NNMT	nicotinamide N-methyltransferase
chr2_-_99917638	12.734	NM_174898	LYG1	lysozyme G-like 1
chr19_+_45417576	12.376		APOC1	apolipoprotein C-I
chr11_-_118900078	12.255	NM_001164280	SLC37A4	solute carrier family 37 (glucose-6-phosphate transporter), member 4
chr21_+_39628869	12.174	NM_170736	KCNJ15	potassium inwardly-rectifying channel, subfamily J, member 15
chr1_-_230849936	12.066		AGT	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
chr12_+_121416294	11.989		HNF1A	HNF1 homeobox A
chr22_+_32439018	11.910	NM_000343	SLC5A1	solute carrier family 5 (sodium/glucose cotransporter), member 1
chr14_+_88490893	11.485		LOC283587	uncharacterized LOC283587
chr16_+_20775311	11.469	NM_005622 NM_202000	ACSM3	acyl-CoA synthetase medium-chain family member 3
chr1_+_47603083	11.347	NM_001010969	CYP4A22	cytochrome P450, family 4, subfamily A, polypeptide 22
chr20_+_56136136	11.319	NM_002591	PCK1	phosphoenolpyruvate carboxykinase 1 (soluble)
chr1_+_94057518	11.318		LOC100129046	uncharacterized LOC100129046
chr2_+_182850550	11.208	NM_001080545	PPP1R1C	protein phosphatase 1, regulatory (inhibitor) subunit 1C
chr8_-_6735438	11.131	NM_005218	DEFB1	defensin, beta 1
chr3_-_157221127	10.983	NM_001167911 NM_001167912	VEPH1	ventricular zone expressed PH domain homolog 1 (zebrafish)
chr1_-_47407142	10.898	NM_000778	CYP4A11	cytochrome P450, family 4, subfamily A, polypeptide 11
chr1_+_94057581	10.662		LOC100129046	uncharacterized LOC100129046
chr19_-_39443326	10.617	NM_148169	FBXO17	F-box protein 17
chr4_+_71494460	10.579	NM_031889	ENAM	enamelin
chr15_+_59903980	10.314	NM_004751	GCNT3	glucosaminyl (N-acetyl) transferase 3, mucin type
chr21_+_39628663	10.301	NM_002243	KCNJ15	potassium inwardly-rectifying channel, subfamily J, member 15
chr11_-_62783281	10.285	NM_001184732 NM_001184733 NM_001184736 NM_004254	SLC22A8	solute carrier family 22 (organic anion transporter), member 8
chr10_+_96698409	10.278	NM_000771	CYP2C9	cytochrome P450, family 2, subfamily C, polypeptide 9
chr22_+_32439250	10.225		SLC5A1	solute carrier family 5 (sodium/glucose cotransporter), member 1
chr6_+_64231626	10.113		PTP4A1	protein tyrosine phosphatase type IVA, member 1
chr4_-_987163	9.759	NM_022042 NM_134425 NM_213613	SLC26A1	solute carrier family 26 (sulfate transporter), member 1
chr7_-_107443631	9.422	NM_000111	SLC26A3	solute carrier family 26, member 3
chr12_-_102874158	9.280		IGF1	insulin-like growth factor 1 (somatomedin C)
chr16_-_55909208	9.054	NM_001143685 NM_145024	CES5A	carboxylesterase 5A
chr13_-_101185944	8.919	NM_033110	A2LD1	AIG2-like domain 1
chr3_-_169587598	8.816	NM_024727	LRRC31	leucine rich repeat containing 31
chr4_-_40516567	8.562		RBM47	RNA binding motif protein 47
chr7_-_122839999	8.505	NM_022444	SLC13A1	solute carrier family 13 (sodium/sulfate symporters), member 1
chr2_-_162931051	8.438	NM_001935	DPP4	dipeptidyl-peptidase 4
chr1_+_54359859	8.379	NM_000792 NM_001039715 NM_001039716 NM_213593	DIO1	deiodinase, iodothyronine, type I
chr5_+_176513819	8.350	NM_002011 NM_213647	FGFR4	fibroblast growth factor receptor 4
chr20_-_22564893	8.338		FOXA2	forkhead box A2
chr16_-_66952729	8.173	NM_001204744 NM_001204745 NM_001204746 NM_004062	CDH16	cadherin 16, KSP-cadherin
chr17_-_202617	7.876	NM_001190411 NM_001190412 NM_001190413 NM_006987	RPH3AL	rabphilin 3A-like (without C2 domains)
chr12_-_8693391	7.690	NM_014358	CLEC4E	C-type lectin domain family 4, member E
chr7_+_141695678	7.610	NM_004668	MGAM	maltase-glucoamylase (alpha-glucosidase)
chr4_+_74301932	7.586	NM_001134	AFP	alpha-fetoprotein
chr17_-_202557	7.464		RPH3AL	rabphilin 3A-like (without C2 domains)
chrX_-_131547536	7.367	NM_001170701 NM_001170702 NM_001170703	MBNL3	muscleblind-like 3 (Drosophila)
chr17_+_68071386	7.211	NM_018658 NM_170741	KCNJ16	potassium inwardly-rectifying channel, subfamily J, member 16
chr1_+_199996729	7.195	NM_003822 NM_205860	NR5A2	nuclear receptor subfamily 5, group A, member 2

Gene overrepresentation in process category:

Enrichment	P-value	GO Accession	GO Term
12.10	6.48e-15	GO:0006805	xenobiotic metabolic process
12.10	6.48e-15	GO:0071466	cellular response to xenobiotic stimulus
12.01	7.66e-15	GO:0009410	response to xenobiotic stimulus
8.02	3.15e-12	GO:0008202	steroid metabolic process
4.22	8.94e-11	GO:0006082	organic acid metabolic process
3.40	7.82e-09	GO:0006629	lipid metabolic process
8.73	4.04e-08	GO:0006820	anion transport
3.77	4.66e-08	GO:0042180	cellular ketone metabolic process
3.74	1.18e-07	GO:0019752	carboxylic acid metabolic process
3.74	1.18e-07	GO:0043436	oxoacid metabolic process
5.23	6.40e-07	GO:0032787	monocarboxylic acid metabolic process
2.20	4.08e-06	GO:0065008	regulation of biological quality
2.30	1.04e-05	GO:0044281	small molecule metabolic process
7.49	1.88e-05	GO:0006814	sodium ion transport
21.33	2.19e-05	GO:0017144	drug metabolic process
10.92	2.22e-05	GO:0015711	organic anion transport
4.09	2.34e-05	GO:0071702	organic substance transport
3.07	2.50e-05	GO:0055085	transmembrane transport
2.09	2.70e-05	GO:0042221	response to chemical stimulus
15.00	4.37e-05	GO:0030193	regulation of blood coagulation
14.27	6.63e-05	GO:0006721	terpenoid metabolic process
1.87	7.12e-05	GO:0051234	establishment of localization
18.28	7.16e-05	GO:0030195	negative regulation of blood coagulation
13.93	8.09e-05	GO:0050818	regulation of coagulation
1.87	9.15e-05	GO:0006810	transport
17.65	9.33e-05	GO:0050819	negative regulation of coagulation
33.23	1.88e-04	GO:0046415	urate metabolic process
12.19	2.41e-04	GO:0061041	regulation of wound healing
30.46	3.18e-04	GO:0051917	regulation of fibrinolysis
13.83	5.61e-04	GO:0008206	bile acid metabolic process
9.59	1.62e-03	GO:0006720	isoprenoid metabolic process
9.59	1.62e-03	GO:0010951	negative regulation of endopeptidase activity
9.59	1.62e-03	GO:0072376	protein activation cascade
2.64	1.62e-03	GO:0006811	ion transport
22.85	1.68e-03	GO:0015721	bile acid and bile salt transport
5.09	1.72e-03	GO:0010817	regulation of hormone levels
2.93	2.37e-03	GO:0044255	cellular lipid metabolic process
73.11	2.40e-03	GO:0034392	negative regulation of smooth muscle cell apoptosis
9.00	2.64e-03	GO:0019748	secondary metabolic process
1.67	2.68e-03	GO:0051179	localization
32.49	3.87e-03	GO:0009812	flavonoid metabolic process
32.49	3.87e-03	GO:0051918	negative regulation of fibrinolysis
5.63	4.12e-03	GO:0042445	hormone metabolic process
13.30	4.72e-03	GO:0001523	retinoid metabolic process
13.30	4.72e-03	GO:0016101	diterpenoid metabolic process
7.80	7.86e-03	GO:0002576	platelet degranulation
7.80	7.86e-03	GO:0034754	cellular hormone metabolic process
54.83	9.51e-03	GO:0015712	hexose phosphate transport
54.83	9.51e-03	GO:0015760	glucose-6-phosphate transport
26.59	9.91e-03	GO:0009698	phenylpropanoid metabolic process
4.97	1.36e-02	GO:0015849	organic acid transport
10.97	1.51e-02	GO:0030301	cholesterol transport
8.53	1.61e-02	GO:0033500	carbohydrate homeostasis
8.53	1.61e-02	GO:0042593	glucose homeostasis
10.70	1.75e-02	GO:0015918	sterol transport
3.60	1.94e-02	GO:0015672	monovalent inorganic cation transport
22.50	2.10e-02	GO:0030194	positive regulation of blood coagulation
43.87	2.35e-02	GO:0051552	flavone metabolic process
20.89	2.91e-02	GO:0042730	fibrinolysis
7.76	3.03e-02	GO:0055088	lipid homeostasis
13.06	3.30e-02	GO:0006776	vitamin A metabolic process
6.36	3.55e-02	GO:0010466	negative regulation of peptidase activity
3.09	3.89e-02	GO:0046903	secretion
19.50	3.93e-02	GO:0050820	positive regulation of coagulation
2.74	4.52e-02	GO:0042060	wound healing
36.56	4.66e-02	GO:0034391	regulation of smooth muscle cell apoptosis
5.31	4.91e-02	GO:0030162	regulation of proteolysis

Gene overrepresentation in compartment category:

Enrichment	P-value	GO Accession	GO Term
7.28	2.03e-10	GO:0045177	apical part of cell
8.27	2.55e-10	GO:0016324	apical plasma membrane
5.94	8.48e-08	GO:0005792	microsome
5.74	1.50e-07	GO:0042598	vesicular fraction
3.25	1.87e-07	GO:0005624	membrane fraction
2.82	3.39e-07	GO:0000267	cell fraction
3.24	3.69e-07	GO:0005615	extracellular space
3.15	4.27e-07	GO:0005626	insoluble fraction
2.15	2.96e-06	GO:0005576	extracellular region
12.66	4.99e-06	GO:0031983	vesicle lumen
2.72	6.19e-06	GO:0044421	extracellular region part
3.12	2.67e-05	GO:0005789	endoplasmic reticulum membrane
12.45	3.40e-05	GO:0031093	platelet alpha granule lumen
12.19	4.04e-05	GO:0034774	secretory granule lumen
3.05	4.25e-05	GO:0042175	nuclear membrane-endoplasmic reticulum network
11.70	5.61e-05	GO:0060205	cytoplasmic membrane-bounded vesicle lumen
2.88	8.06e-05	GO:0044432	endoplasmic reticulum part
10.26	1.59e-04	GO:0031091	platelet alpha granule
2.44	1.91e-04	GO:0005783	endoplasmic reticulum
15.13	3.55e-04	GO:0031526	brush border membrane
11.38	3.77e-04	GO:0005903	brush border
1.76	8.04e-03	GO:0044459	plasma membrane part
31.33	1.35e-02	GO:0005577	fibrinogen complex
31.33	1.35e-02	GO:0046581	intercellular canaliculus
1.34	2.40e-02	GO:0044425	membrane part
1.28	3.14e-02	GO:0016020	membrane
12.19	4.65e-02	GO:0034364	high-density lipoprotein particle

Gene overrepresentation in function category:

Enrichment	P-value	GO Accession	GO Term
33.95	3.67e-15	GO:0015020	glucuronosyltransferase activity
8.68	2.26e-07	GO:0008194	UDP-glycosyltransferase activity
6.31	5.06e-07	GO:0015291	secondary active transmembrane transporter activity
4.52	2.60e-06	GO:0022804	active transmembrane transporter activity
29.25	7.90e-06	GO:0008514	organic anion transmembrane transporter activity
5.95	2.98e-05	GO:0016758	transferase activity, transferring hexosyl groups
6.47	3.26e-05	GO:0008509	anion transmembrane transporter activity
13.00	4.30e-05	GO:0015103	inorganic anion transmembrane transporter activity
4.57	6.02e-05	GO:0004857	enzyme inhibitor activity
6.75	6.33e-05	GO:0015293	symporter activity
8.50	7.63e-05	GO:0015294	solute:cation symporter activity
7.86	1.60e-04	GO:0015081	sodium ion transmembrane transporter activity
5.97	2.40e-04	GO:0046873	metal ion transmembrane transporter activity
10.45	2.49e-04	GO:0033293	monocarboxylic acid binding
41.78	3.31e-04	GO:0005436	sodium:phosphate symporter activity
14.15	9.68e-04	GO:0015296	anion:cation symporter activity
4.20	1.97e-03	GO:0016757	transferase activity, transferring glycosyl groups
26.59	2.99e-03	GO:0001972	retinoic acid binding
2.39	3.50e-03	GO:0022857	transmembrane transporter activity
2.19	3.64e-03	GO:0005215	transporter activity
3.16	5.11e-03	GO:0008289	lipid binding
2.29	5.46e-03	GO:0022892	substrate-specific transporter activity
22.50	6.33e-03	GO:0015114	phosphate transmembrane transporter activity
6.73	7.12e-03	GO:0004867	serine-type endopeptidase inhibitor activity
9.97	8.00e-03	GO:0043498	cell surface binding
5.01	9.35e-03	GO:0004866	endopeptidase inhibitor activity
4.91	1.11e-02	GO:0031406	carboxylic acid binding
4.81	1.32e-02	GO:0061135	endopeptidase regulator activity
4.75	1.47e-02	GO:0030414	peptidase inhibitor activity
2.31	1.78e-02	GO:0022891	substrate-specific transmembrane transporter activity
3.77	2.57e-02	GO:0022890	inorganic cation transmembrane transporter activity
2.22	2.57e-02	GO:0030234	enzyme regulator activity
5.63	2.57e-02	GO:0005342	organic acid transmembrane transporter activity
9.88	4.00e-02	GO:0005504	fatty acid binding
3.01	4.45e-02	GO:0030246	carbohydrate binding