Motif ID: HSF1,2.p2

Z-value: 1.872


Transcription factors associated with HSF1,2.p2:

Gene SymbolEntrez IDGene Name
HSF1 3297 heat shock transcription factor 1
HSF2 3298 heat shock transcription factor 2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
HSF2hg19_v1_chr6_+_122720685_1227207060.144.6e-01Click!
HSF1hg19_v1_chr8_+_145515285_1455152860.115.4e-01Click!


Activity profile for motif HSF1,2.p2.

activity profile for motif HSF1,2.p2


Sorted Z-values histogram for motif HSF1,2.p2

Sorted Z-values for motif HSF1,2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of HSF1,2.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr19_-_42947050 4.466 NM_198477
CXCL17
chemokine (C-X-C motif) ligand 17
chr11_-_119294242 4.317 NM_006288
THY1
Thy-1 cell surface antigen
chr5_-_112770537 4.098 NM_032028
TSSK1B
testis-specific serine kinase 1B
chr5_-_110062365 3.995 NM_001039763
TMEM232
transmembrane protein 232
chr1_+_109648593 3.980


chr4_-_159956332 3.447 NM_152543
C4orf45
chromosome 4 open reading frame 45
chr12_+_107078476 3.446 NM_032491
RFX4
regulatory factor X, 4 (influences HLA class II expression)
chr10_+_122216465 3.301 NM_001030059
PPAPDC1A
phosphatidic acid phosphatase type 2 domain containing 1A
chr6_+_159309618 3.211 NM_001195032
C6orf99
chromosome 6 open reading frame 99
chr17_+_9745847 3.175 GLP2R
glucagon-like peptide 2 receptor
chr18_+_29171729 3.164 NM_000371
TTR
transthyretin
chr19_-_14629227 2.956 DNAJB1
DnaJ (Hsp40) homolog, subfamily B, member 1
chr3_-_165555167 2.934 BCHE
butyrylcholinesterase
chr3_+_45067750 2.933 NM_003278
CLEC3B
C-type lectin domain family 3, member B
chr13_+_53602829 2.875 NM_006418
OLFM4
olfactomedin 4
chr6_+_151646634 2.844 NM_144497
AKAP12
A kinase (PRKA) anchor protein 12
chr19_+_6135650 2.806 NM_030924
ACSBG2
acyl-CoA synthetase bubblegum family member 2
chr7_-_120498128 2.791 NM_012338
TSPAN12
tetraspanin 12
chr19_-_14629235 2.752


chr19_-_14629160 2.683 NM_006145
DNAJB1
DnaJ (Hsp40) homolog, subfamily B, member 1

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 6 of 6 entries
Enrichment   P-value GO Accession GO Term
14.64 1.35e-02 GO:0071804 cellular potassium ion transport
14.64 1.35e-02 GO:0071805 potassium ion transmembrane transport
1.88 8.72e-03 GO:0042221 response to chemical stimulus
1.73 1.34e-03 GO:0007275 multicellular organismal development
1.70 2.93e-02 GO:0048731 system development
1.63 7.47e-03 GO:0032502 developmental process

Gene overrepresentation in compartment category:

Showing 1 to 5 of 5 entries
Enrichment   P-value GO Accession GO Term
3.89 2.06e-03 GO:0005578 proteinaceous extracellular matrix
3.77 7.36e-04 GO:0031012 extracellular matrix
3.42 8.74e-10 GO:0044421 extracellular region part
3.19 5.58e-06 GO:0005615 extracellular space
2.72 6.54e-12 GO:0005576 extracellular region

Nothing significant found in function category.