Motif ID: IKZF1.p2

Z-value: 1.235


Transcription factors associated with IKZF1.p2:

Gene SymbolEntrez IDGene Name
IKZF1 10320 IKAROS family zinc finger 1 (Ikaros)

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
IKZF1hg19_v1_chr7_+_50348255_50348383-0.354.8e-02Click!


Activity profile for motif IKZF1.p2.

activity profile for motif IKZF1.p2


Sorted Z-values histogram for motif IKZF1.p2

Sorted Z-values for motif IKZF1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of IKZF1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr12_-_49259549 4.235 NM_014470
 RND1
Rho family GTPase 1
chr11_-_35440514 3.463 SLC1A2
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr12_-_322612 3.171 NM_003044
NM_001122847
 SLC6A12

solute carrier family 6 (neurotransmitter transporter, betaine/GABA), member 12

chr4_-_155533882 2.872 NM_000509
NM_021870
 FGG

fibrinogen gamma chain

chr4_-_155533800 2.830 FGG
fibrinogen gamma chain
chr4_-_155533850 2.819 FGG
fibrinogen gamma chain
chr10_+_135340865 2.786 NM_000773
 CYP2E1
cytochrome P450, family 2, subfamily E, polypeptide 1
chr11_-_35441501 2.615 NM_001195728
NM_001252652
 SLC1A2

solute carrier family 1 (glial high affinity glutamate transporter), member 2

chr1_-_160039946 2.569 NM_002241
 KCNJ10
potassium inwardly-rectifying channel, subfamily J, member 10
chr4_-_155533757 2.518 FGG
fibrinogen gamma chain
chr20_+_56136136 2.491 NM_002591
 PCK1
phosphoenolpyruvate carboxykinase 1 (soluble)
chr17_+_7517263 2.441 SHBG
sex hormone-binding globulin
chr4_-_176733413 2.403 GPM6A
glycoprotein M6A
chr16_+_56703725 2.227 NM_005951
 MT1H
metallothionein 1H
chr4_-_176733901 2.119 GPM6A
glycoprotein M6A
chr2_+_17721806 2.088 NM_003385
 VSNL1
visinin-like 1
chr11_-_35441099 2.073 NM_004171
 SLC1A2
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr18_-_74728963 2.030 MBP
myelin basic protein
chr2_+_17721983 2.016 VSNL1
visinin-like 1
chr18_-_74729049 1.977 NM_001025081
NM_001025090
NM_001025092
NM_002385
 MBP



myelin basic protein




Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 7 of 7 entries
Enrichment   P-value GO Accession GO Term
17.89 2.74e-02 GO:0007269 neurotransmitter secretion
6.37 3.53e-03 GO:0007268 synaptic transmission
6.30 1.15e-03 GO:0019226 transmission of nerve impulse
6.30 1.15e-03 GO:0035637 multicellular organismal signaling
4.12 4.51e-02 GO:0007267 cell-cell signaling
3.73 2.22e-02 GO:0007154 cell communication
2.64 1.33e-02 GO:0042221 response to chemical stimulus

Gene overrepresentation in compartment category:

Showing 1 to 9 of 9 entries
Enrichment   P-value GO Accession GO Term
80.43 2.22e-02 GO:0005577 fibrinogen complex
80.43 2.22e-02 GO:0030673 axolemma
24.14 2.16e-02 GO:0032994 protein-lipid complex
24.14 2.16e-02 GO:0034358 plasma lipoprotein particle
6.99 1.67e-02 GO:0042598 vesicular fraction
4.43 8.73e-04 GO:0005624 membrane fraction
4.29 1.21e-03 GO:0005626 insoluble fraction
3.82 7.79e-04 GO:0000267 cell fraction
2.93 4.63e-02 GO:0005887 integral to plasma membrane

Nothing significant found in function category.