Motif ID: KLF12.p2

Z-value: 2.244


Transcription factors associated with KLF12.p2:

Gene SymbolEntrez IDGene Name
KLF12 11278 Kruppel-like factor 12

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
KLF12hg19_v1_chr13_-_74708361_74708431-0.327.0e-02Click!


Activity profile for motif KLF12.p2.

activity profile for motif KLF12.p2


Sorted Z-values histogram for motif KLF12.p2

Sorted Z-values for motif KLF12.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of KLF12.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_+_159175048 5.958 NM_001122951
 DARC
Duffy blood group, chemokine receptor
chr1_+_170633312 5.049 NM_006902
NM_022716
 PRRX1

paired related homeobox 1

chr17_-_48265912 4.461 COL1A1
collagen, type I, alpha 1
chr14_+_63671101 4.111 NM_020663
 RHOJ
ras homolog gene family, member J
chr15_-_65360297 3.272 NM_016563
 RASL12
RAS-like, family 12
chr12_+_54378929 3.086 NM_017409
 HOXC10
homeobox C10
chr10_-_75401199 3.067 MYOZ1
myozenin 1
chr10_-_118501981 3.054 NM_025015
 HSPA12A
heat shock 70kDa protein 12A
chr7_+_123295860 2.937 NM_207163
 LMOD2
leiomodin 2 (cardiac)
chr10_-_119301750 2.761 EMX2OS
EMX2 opposite strand/antisense RNA (non-protein coding)
chr17_+_48262816 2.754


chr17_-_37353731 2.745 NM_000723
NM_199247
NM_199248
 CACNB1


calcium channel, voltage-dependent, beta 1 subunit


chr10_-_75401492 2.728 NM_021245
 MYOZ1
myozenin 1
chr1_-_203317366 2.676 FMOD
fibromodulin
chr8_-_82359620 2.666 NM_002677
 PMP2
peripheral myelin protein 2
chr21_-_48024985 2.626 NM_006272
 S100B
S100 calcium binding protein B
chrX_+_153046422 2.553 NM_001170760
NM_001170761
NM_014370
 SRPK3


SRSF protein kinase 3


chr2_+_176994421 2.551 NM_001199747
NM_001199746
NM_019558
 HOXD8


homeobox D8


chr20_+_34742656 2.543 NM_012156
 EPB41L1
erythrocyte membrane protein band 4.1-like 1
chr3_-_87040246 2.463 NM_016206
 VGLL3
vestigial like 3 (Drosophila)

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 44 entries
Enrichment   P-value GO Accession GO Term
22.19 2.05e-03 GO:0008038 neuron recognition
11.96 8.68e-03 GO:0055002 striated muscle cell development
11.49 1.10e-02 GO:0032412 regulation of ion transmembrane transporter activity
11.06 1.38e-02 GO:0022898 regulation of transmembrane transporter activity
10.65 1.71e-02 GO:0055001 muscle cell development
10.46 1.90e-02 GO:0034765 regulation of ion transmembrane transport
10.28 2.11e-02 GO:0008037 cell recognition
9.45 3.42e-02 GO:0007519 skeletal muscle tissue development
9.45 3.42e-02 GO:0032409 regulation of transporter activity
8.88 4.89e-02 GO:0060538 skeletal muscle organ development
8.78 3.04e-03 GO:0030326 embryonic limb morphogenesis
8.78 3.04e-03 GO:0035113 embryonic appendage morphogenesis
7.96 5.90e-07 GO:0007517 muscle organ development
7.74 7.84e-03 GO:0035107 appendage morphogenesis
7.74 7.84e-03 GO:0035108 limb morphogenesis
7.44 1.05e-02 GO:0048736 appendage development
7.44 1.05e-02 GO:0060173 limb development
6.41 1.19e-06 GO:0061061 muscle structure development
6.20 3.92e-02 GO:0042692 muscle cell differentiation
6.11 1.49e-02 GO:0043062 extracellular structure organization

Gene overrepresentation in compartment category:

Showing 1 to 15 of 15 entries
Enrichment   P-value GO Accession GO Term
58.57 1.63e-03 GO:0014701 junctional sarcoplasmic reticulum membrane
18.60 8.71e-03 GO:0033017 sarcoplasmic reticulum membrane
13.20 5.58e-03 GO:0016529 sarcoplasmic reticulum
12.85 6.37e-03 GO:0016528 sarcoplasm
8.14 1.49e-02 GO:0042383 sarcolemma
7.42 2.49e-02 GO:0014069 postsynaptic density
5.90 3.01e-02 GO:0030016 myofibril
5.56 4.31e-02 GO:0043292 contractile fiber
4.06 7.52e-04 GO:0031012 extracellular matrix
3.78 1.78e-03 GO:0045202 synapse
3.75 3.85e-03 GO:0009986 cell surface
1.97 2.31e-03 GO:0044459 plasma membrane part
1.85 3.20e-02 GO:0005576 extracellular region
1.78 1.68e-05 GO:0071944 cell periphery
1.78 2.19e-05 GO:0005886 plasma membrane

Nothing significant found in function category.