Motif ID: KLF4.p3

Z-value: 2.499


Transcription factors associated with KLF4.p3:

Gene SymbolEntrez IDGene Name
KLF4 9314 Kruppel-like factor 4 (gut)

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
KLF4hg19_v1_chr9_-_110251754_1102519260.709.4e-06Click!


Activity profile for motif KLF4.p3.

activity profile for motif KLF4.p3


Sorted Z-values histogram for motif KLF4.p3

Sorted Z-values for motif KLF4.p3



Network of associatons between targets according to the STRING database.



First level regulatory network of KLF4.p3

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_-_38471170 4.829 NM_001243878
NM_004468
FHL3

four and a half LIM domains 3

chr9_-_110251754 4.552 KLF4
Kruppel-like factor 4 (gut)
chr4_+_154387450 4.474 NM_001131007
NM_015196
KIAA0922

KIAA0922

chrX_-_153599581 4.465 FLNA
filamin A, alpha
chr18_+_11981457 4.450 IMPA2
inositol(myo)-1(or 4)-monophosphatase 2
chr22_-_36784001 4.412 MYH9
myosin, heavy chain 9, non-muscle
chr18_+_11981552 4.407 IMPA2
inositol(myo)-1(or 4)-monophosphatase 2
chr22_-_36783851 4.238 MYH9
myosin, heavy chain 9, non-muscle
chr8_+_37553269 4.098 NM_025069
ZNF703
zinc finger protein 703
chr22_-_36783930 4.077 MYH9
myosin, heavy chain 9, non-muscle
chr17_+_81037504 3.941 NM_001004431
METRNL
meteorin, glial cell differentiation regulator-like
chr1_+_154975041 3.835 NM_001252405
NM_015872
ZBTB7B

zinc finger and BTB domain containing 7B

chr15_+_90931505 3.729 IQGAP1
IQ motif containing GTPase activating protein 1
chr19_+_54371170 3.699 MYADM
myeloid-associated differentiation marker
chr18_+_11981421 3.677 NM_014214
IMPA2
inositol(myo)-1(or 4)-monophosphatase 2
chr2_+_85132999 3.666 TMSB10
thymosin beta 10
chr1_-_9189087 3.659 NM_024980
GPR157
G protein-coupled receptor 157
chrX_+_152990322 3.642 NM_000033
ABCD1
ATP-binding cassette, sub-family D (ALD), member 1
chr7_-_102257135 3.642 RASA4
RAS p21 protein activator 4
chr15_+_90931489 3.624 IQGAP1
IQ motif containing GTPase activating protein 1
chr19_-_6767417 3.588 NM_005490
SH2D3A
SH2 domain containing 3A
chr12_+_57916607 3.580 NM_052897
MBD6
methyl-CpG binding domain protein 6
chr22_-_36783977 3.570 MYH9
myosin, heavy chain 9, non-muscle
chr11_+_819696 3.542 PNPLA2
patatin-like phospholipase domain containing 2
chr7_-_102257199 3.539 NM_001079877
NM_006989
RASA4

RAS p21 protein activator 4

chr11_-_73694297 3.448 UCP2
uncoupling protein 2 (mitochondrial, proton carrier)
chr15_+_90931509 3.413 IQGAP1
IQ motif containing GTPase activating protein 1
chr9_-_130533509 3.297 NM_001252334
NM_005489
SH2D3C

SH2 domain containing 3C

chr19_+_54371150 3.270 MYADM
myeloid-associated differentiation marker
chr5_+_40680042 3.225 PTGER4
prostaglandin E receptor 4 (subtype EP4)
chr19_+_45504686 3.224 NM_006509
RELB
v-rel reticuloendotheliosis viral oncogene homolog B
chr19_+_54371125 3.213 NM_001020819
NM_138373
MYADM

myeloid-associated differentiation marker

chr2_+_11295569 3.209 PQLC3
PQ loop repeat containing 3
chr20_+_62371218 3.185 SLC2A4RG
SLC2A4 regulator
chr16_+_30676098 3.175 FBRS
fibrosin
chr2_-_37898768 3.110 CDC42EP3
CDC42 effector protein (Rho GTPase binding) 3
chr5_+_40680021 3.039 NM_000958
PTGER4
prostaglandin E receptor 4 (subtype EP4)
chr9_-_110252045 3.007 NM_004235
KLF4
Kruppel-like factor 4 (gut)
chr2_-_16847070 3.002 NM_030797
FAM49A
family with sequence similarity 49, member A
chr15_+_90931470 2.992 NM_003870
IQGAP1
IQ motif containing GTPase activating protein 1
chr19_+_3178735 2.970 NM_003775
S1PR4
sphingosine-1-phosphate receptor 4
chr16_+_89238160 2.918 NM_004933
CDH15
cadherin 15, type 1, M-cadherin (myotubule)
chr8_-_37756971 2.870 NM_001002814
NM_025151
RAB11FIP1

RAB11 family interacting protein 1 (class I)

chr19_-_47734215 2.859 NM_014417
BBC3
BCL2 binding component 3
chr14_-_21566497 2.855 ZNF219
zinc finger protein 219
chr2_+_11295602 2.830 PQLC3
PQ loop repeat containing 3
chrX_-_153599719 2.826 FLNA
filamin A, alpha
chr10_-_126849556 2.722 NM_001083914
CTBP2
C-terminal binding protein 2
chr18_+_77155966 2.716 NFATC1
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
chr9_+_140500097 2.709 ARRDC1
arrestin domain containing 1
chr17_+_76164624 2.706 NM_004710
SYNGR2
synaptogyrin 2
chr3_+_127391768 2.688 NM_032548
NM_172027
ABTB1

ankyrin repeat and BTB (POZ) domain containing 1

chr15_+_90931449 2.676 IQGAP1
IQ motif containing GTPase activating protein 1
chr17_-_73840422 2.672 UNC13D
unc-13 homolog D (C. elegans)
chr6_+_35420149 2.657 FANCE
Fanconi anemia, complementation group E
chr11_-_73693820 2.652 UCP2
uncoupling protein 2 (mitochondrial, proton carrier)
chr7_+_97911023 2.651 BRI3
brain protein I3
chr22_-_36784055 2.592 NM_002473
MYH9
myosin, heavy chain 9, non-muscle
chr10_+_75757847 2.586 NM_003373
NM_014000
VCL

vinculin

chr11_-_73693883 2.567 NM_003355
UCP2
uncoupling protein 2 (mitochondrial, proton carrier)
chrX_+_117629871 2.564 NM_144658
DOCK11
dedicator of cytokinesis 11
chr5_+_133861344 2.562 PHF15
PHD finger protein 15
chr12_-_58240746 2.560 NM_005730
CTDSP2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2
chr20_-_52210780 2.530 ZNF217
zinc finger protein 217
chr17_-_66453561 2.513 NM_017983
WIPI1
WD repeat domain, phosphoinositide interacting 1
chr4_+_3076236 2.499 NM_002111
HTT
huntingtin
chr15_-_72612247 2.491 NM_001172684
CELF6
CUGBP, Elav-like family member 6
chr21_+_17102370 2.482 NM_013396
USP25
ubiquitin specific peptidase 25
chr1_-_36851484 2.478 NM_032017
STK40
serine/threonine kinase 40
chr6_+_35420115 2.465 NM_021922
FANCE
Fanconi anemia, complementation group E
chr17_+_78234626 2.457 NM_020914
NM_020954
RNF213

ring finger protein 213

chr2_-_37899227 2.456 NM_006449
CDC42EP3
CDC42 effector protein (Rho GTPase binding) 3
chr19_+_14544216 2.446 PKN1
protein kinase N1
chrX_+_49028183 2.435 NM_002668
PLP2
proteolipid protein 2 (colonic epithelium-enriched)
chr22_+_43547526 2.435 NM_000714
NM_007311
TSPO

translocator protein (18kDa)

chr7_+_21467572 2.433 NM_003112
SP4
Sp4 transcription factor
chr20_+_62371109 2.430 NM_020062
SLC2A4RG
SLC2A4 regulator
chr19_-_10679328 2.429 CDKN2D
cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
chr12_-_58240472 2.426 CTDSP2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2
chr17_-_7382804 2.396 ZBTB4
zinc finger and BTB domain containing 4
chr11_-_2292181 2.385 NM_005170
ASCL2
achaete-scute complex homolog 2 (Drosophila)
chr20_+_35089817 2.384 NM_001042486
DLGAP4
discs, large (Drosophila) homolog-associated protein 4
chr4_+_38665587 2.365 NM_016531
KLF3
Kruppel-like factor 3 (basic)
chr9_+_140500136 2.361 ARRDC1
arrestin domain containing 1
chr16_-_88752788 2.352 SNAI3
snail homolog 3 (Drosophila)
chr3_+_50273645 2.333 NM_002070
GNAI2
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
chr11_-_64014140 2.328 PPP1R14B
protein phosphatase 1, regulatory (inhibitor) subunit 14B
chr1_-_154155594 2.319 TPM3
tropomyosin 3
chrX_+_48398048 2.298 NM_002536
TBC1D25
TBC1 domain family, member 25
chr5_+_95998170 2.293 CAST
calpastatin
chr15_+_65134081 2.291 NM_001195059
NM_025201
PLEKHO2

pleckstrin homology domain containing, family O member 2

chr1_-_115632047 2.285 NM_005725
TSPAN2
tetraspanin 2
chr19_-_10679620 2.274 NM_001800
NM_079421
CDKN2D

cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)

chr17_-_28257017 2.265 NM_033389
SSH2
slingshot homolog 2 (Drosophila)
chr8_+_22457098 2.233 NM_001013842
NM_001198827
NM_173686
C8orf58


chromosome 8 open reading frame 58


chr9_-_139890984 2.225 NM_004669
CLIC3
chloride intracellular channel 3
chr1_-_36851517 2.219 STK40
serine/threonine kinase 40
chr1_-_153508463 2.213 S100A6
S100 calcium binding protein A6
chr9_+_140500156 2.212


chr11_-_64645925 2.210 EHD1
EH-domain containing 1
chr2_+_238600878 2.207 LRRFIP1
leucine rich repeat (in FLII) interacting protein 1
chr9_+_95858561 2.195 C9orf89
chromosome 9 open reading frame 89
chr1_+_154975201 2.192 NM_001252406
ZBTB7B
zinc finger and BTB domain containing 7B
chr6_-_31550065 2.187 NM_002341
NM_009588
LTB

lymphotoxin beta (TNF superfamily, member 3)

chr19_+_48828820 2.178 EMP3
epithelial membrane protein 3
chr3_+_50273648 2.175 GNAI2
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
chr1_+_26856252 2.170 RPS6KA1
ribosomal protein S6 kinase, 90kDa, polypeptide 1
chr2_+_11295539 2.165 NM_152391
PQLC3
PQ loop repeat containing 3
chr12_+_68042493 2.161 NM_003583
NM_006482
DYRK2

dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2

chr19_-_14116875 2.138 RFX1
regulatory factor X, 1 (influences HLA class II expression)
chr3_+_50273575 2.136 GNAI2
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
chr20_+_34894190 2.133 DLGAP4
discs, large (Drosophila) homolog-associated protein 4
chr1_+_26856259 2.115 RPS6KA1
ribosomal protein S6 kinase, 90kDa, polypeptide 1
chr1_+_26856240 2.112 NM_002953
RPS6KA1
ribosomal protein S6 kinase, 90kDa, polypeptide 1
chr17_+_75277491 2.101 NM_001113491
SEPT9
septin 9
chr1_-_154155698 2.092 NM_001043351
NM_001043352
NM_001043353
NM_153649
TPM3



tropomyosin 3



chr19_+_10713055 2.083 NM_001145056
SLC44A2
solute carrier family 44, member 2
chr5_+_176853673 2.080 NM_001004105
NM_001004106
NM_002082
GRK6


G protein-coupled receptor kinase 6


chr16_+_66638652 2.079 CMTM3
CKLF-like MARVEL transmembrane domain containing 3
chr7_+_65338349 2.074 VKORC1L1
vitamin K epoxide reductase complex, subunit 1-like 1
chr20_+_43803539 2.071 NM_002638
PI3
peptidase inhibitor 3, skin-derived
chr9_+_140500148 2.070 ARRDC1
arrestin domain containing 1
chr12_+_69004708 2.069 RAP1B
RAP1B, member of RAS oncogene family
chr3_+_50273745 2.068 GNAI2
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
chr1_-_156470538 2.067 MEF2D
myocyte enhancer factor 2D
chrX_-_135056132 2.066 NM_173470
MMGT1
membrane magnesium transporter 1
chr20_-_62711160 2.065 NM_001039467
RGS19
regulator of G-protein signaling 19
chr14_+_64319607 2.064 NM_015180
NM_182914
SYNE2

spectrin repeat containing, nuclear envelope 2

chr10_-_104001229 2.060 NM_005029
PITX3
paired-like homeodomain 3
chr16_+_30675777 2.057 NM_001105079
FBRS
fibrosin
chr3_+_50273674 2.032 GNAI2
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
chr1_-_154155680 2.027 TPM3
tropomyosin 3
chr12_-_58240493 2.024 CTDSP2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2
chr3_+_50649292 2.003 NM_001243926
MAPKAPK3
mitogen-activated protein kinase-activated protein kinase 3
chr1_-_154155646 2.002 TPM3
tropomyosin 3
chr16_-_67281312 2.001 FHOD1
formin homology 2 domain containing 1
chrY_-_1521733 1.996 NM_001173474
NM_004192
ASMTL

acetylserotonin O-methyltransferase-like

chr19_+_17581276 1.989 NM_198580
SLC27A1
solute carrier family 27 (fatty acid transporter), member 1
chr3_+_50273635 1.983 GNAI2
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
chr12_-_58240446 1.980 CTDSP2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2
chr3_+_133495925 1.978 TF
transferrin
chr19_+_4679293 1.975 NM_001242901
LOC100131094
uncharacterized LOC100131094
chr1_+_150521786 1.968 NM_019032
NM_025008
ADAMTSL4

ADAMTS-like 4

chr11_-_75236418 1.966 NM_030792
GDPD5
glycerophosphodiester phosphodiesterase domain containing 5
chr7_+_65338343 1.960 VKORC1L1
vitamin K epoxide reductase complex, subunit 1-like 1
chr3_+_38206968 1.955 NM_005109
OXSR1
oxidative-stress responsive 1
chr16_-_67281398 1.951 NM_013241
FHOD1
formin homology 2 domain containing 1
chrX_+_64887510 1.931 NM_002444
MSN
moesin
chr9_-_139581795 1.930 AGPAT2
1-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta)
chr19_+_54695103 1.928 NM_001077446
TSEN34
tRNA splicing endonuclease 34 homolog (S. cerevisiae)
chr5_+_133450353 1.921 NM_003202
TCF7
transcription factor 7 (T-cell specific, HMG-box)
chr19_-_40971623 1.920 NM_000713
BLVRB
biliverdin reductase B (flavin reductase (NADPH))
chr11_+_65082288 1.919 NM_006779
CDC42EP2
CDC42 effector protein (Rho GTPase binding) 2
chr2_+_219264719 1.915 CTDSP1
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
chr19_+_42788605 1.915 NM_015125
CIC
capicua homolog (Drosophila)
chr2_-_220252513 1.911 DNPEP
aspartyl aminopeptidase
chr12_-_109125289 1.908 NM_014325
CORO1C
coronin, actin binding protein, 1C
chr1_+_226250413 1.908 H3F3A
H3 histone, family 3A
chr4_-_2935851 1.905 NM_001120
MFSD10
major facilitator superfamily domain containing 10
chr14_-_92302612 1.897 NM_001128595
NM_152332
TC2N

tandem C2 domains, nuclear

chr1_-_154155685 1.890 TPM3
tropomyosin 3
chr1_-_33815411 1.889 PHC2
polyhomeotic homolog 2 (Drosophila)
chr19_-_2038937 1.887 MKNK2
MAP kinase interacting serine/threonine kinase 2
chr9_+_95858449 1.886 NM_032310
C9orf89
chromosome 9 open reading frame 89
chr1_-_33168356 1.884 NM_001161708
NM_030786
SYNC

syncoilin, intermediate filament protein

chr7_-_128049959 1.883 IMPDH1
IMP (inosine 5'-monophosphate) dehydrogenase 1
chr7_+_97910978 1.868 NM_001159491
NM_015379
BRI3

brain protein I3

chr3_+_38207247 1.867 OXSR1
oxidative-stress responsive 1
chr8_+_26149080 1.865 PPP2R2A
protein phosphatase 2, regulatory subunit B, alpha
chr8_-_12990502 1.865 DLC1
deleted in liver cancer 1
chr19_+_6739697 1.864 NM_004240
TRIP10
thyroid hormone receptor interactor 10
chr17_+_7239847 1.864 NM_014716
ACAP1
ArfGAP with coiled-coil, ankyrin repeat and PH domains 1
chr1_+_29213569 1.858 NM_001166005
NM_001166007
NM_004437
NM_203342
NM_203343
EPB41




erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked)




chr12_+_69004710 1.857 RAP1B
RAP1B, member of RAS oncogene family
chr19_+_7985884 1.856 SNAPC2
small nuclear RNA activating complex, polypeptide 2, 45kDa
chr9_+_127539382 1.855 NM_182487
OLFML2A
olfactomedin-like 2A
chr5_+_95998678 1.853 CAST
calpastatin
chr1_-_154155636 1.852 TPM3
tropomyosin 3
chr1_-_154155637 1.848 TPM3
tropomyosin 3
chr7_+_36192844 1.844 EEPD1
endonuclease/exonuclease/phosphatase family domain containing 1
chr12_+_69004684 1.838 RAP1B
RAP1B, member of RAS oncogene family
chr19_-_18632886 1.823 NM_006532
ELL
elongation factor RNA polymerase II
chr7_-_128045995 1.822 NM_001142573
NM_001142574
NM_001142575
IMPDH1


IMP (inosine 5'-monophosphate) dehydrogenase 1


chrX_-_1572648 1.819 NM_001173473
ASMTL
acetylserotonin O-methyltransferase-like
chr16_-_67281393 1.810 FHOD1
formin homology 2 domain containing 1
chr12_-_122231554 1.808 NM_019034
RHOF
ras homolog gene family, member F (in filopodia)
chr12_-_48298765 1.808 NM_000376
NM_001017535
NM_001017536
VDR


vitamin D (1,25- dihydroxyvitamin D3) receptor


chr1_+_2487803 1.805 NM_003820
TNFRSF14
tumor necrosis factor receptor superfamily, member 14
chr11_-_64014264 1.798 PPP1R14B
protein phosphatase 1, regulatory (inhibitor) subunit 14B
chr20_-_56884488 1.796 PPP4R1L
protein phosphatase 4, regulatory subunit 1-like
chr16_+_29817810 1.787 NM_001042539
NM_002383
MAZ

MYC-associated zinc finger protein (purine-binding transcription factor)

chr1_+_12227050 1.784 NM_001066
TNFRSF1B
tumor necrosis factor receptor superfamily, member 1B
chr22_+_50354428 1.783 PIM3
pim-3 oncogene
chr16_-_88752879 1.782 NM_178310
SNAI3
snail homolog 3 (Drosophila)
chr6_-_41702734 1.782 NM_007162
TFEB
transcription factor EB
chr11_+_2466171 1.781 NM_000218
KCNQ1
potassium voltage-gated channel, KQT-like subfamily, member 1
chr4_-_2935650 1.770 MFSD10
major facilitator superfamily domain containing 10
chrY_-_1522648 1.769 NM_001173473
ASMTL
acetylserotonin O-methyltransferase-like
chr6_-_30654978 1.767 PPP1R18
protein phosphatase 1, regulatory subunit 18
chr12_-_58240217 1.767 CTDSP2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
1.47 1.37e-10 GO:0050794 regulation of cellular process
1.45 1.39e-10 GO:0050789 regulation of biological process
1.41 4.89e-10 GO:0065007 biological regulation
1.84 5.24e-08 GO:0048518 positive regulation of biological process
1.67 7.47e-07 GO:0007165 signal transduction
2.21 8.20e-07 GO:0035556 intracellular signal transduction
1.56 1.24e-05 GO:0019222 regulation of metabolic process
1.58 1.59e-05 GO:0023052 signaling
1.53 2.70e-05 GO:0051716 cellular response to stimulus
1.73 5.38e-05 GO:0048522 positive regulation of cellular process
1.56 9.24e-05 GO:0031323 regulation of cellular metabolic process
1.56 1.40e-04 GO:0080090 regulation of primary metabolic process
1.83 1.57e-04 GO:0048583 regulation of response to stimulus
1.89 2.25e-04 GO:0023051 regulation of signaling
1.96 3.20e-04 GO:0009966 regulation of signal transduction
3.36 6.62e-04 GO:0030029 actin filament-based process
1.70 1.35e-03 GO:0048523 negative regulation of cellular process
1.52 1.63e-03 GO:0060255 regulation of macromolecule metabolic process
1.34 1.68e-03 GO:0050896 response to stimulus
2.65 2.08e-03 GO:0007010 cytoskeleton organization
1.64 2.40e-03 GO:0048519 negative regulation of biological process
2.15 3.24e-03 GO:0006351 transcription, DNA-dependent
3.39 3.34e-03 GO:0030036 actin cytoskeleton organization
1.63 5.50e-03 GO:0051252 regulation of RNA metabolic process
2.68 8.68e-03 GO:0007243 intracellular protein kinase cascade
2.68 8.68e-03 GO:0023014 signal transduction via phosphorylation event
1.57 1.10e-02 GO:0010468 regulation of gene expression
2.19 1.13e-02 GO:0006468 protein phosphorylation
1.55 1.17e-02 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.54 1.33e-02 GO:0051171 regulation of nitrogen compound metabolic process
2.15 1.80e-02 GO:0006955 immune response
1.98 1.91e-02 GO:0032774 RNA biosynthetic process
1.84 2.31e-02 GO:0002376 immune system process
1.15 2.90e-02 GO:0009987 cellular process
4.04 3.19e-02 GO:0034329 cell junction assembly
1.52 3.21e-02 GO:0009889 regulation of biosynthetic process
1.54 3.32e-02 GO:0010556 regulation of macromolecule biosynthetic process
1.52 3.55e-02 GO:0031326 regulation of cellular biosynthetic process
1.55 3.77e-02 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.58 4.76e-02 GO:0006355 regulation of transcription, DNA-dependent
1.91 4.80e-02 GO:0006793 phosphorus metabolic process
1.91 4.80e-02 GO:0006796 phosphate metabolic process

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
1.21 4.54e-08 GO:0005622 intracellular
1.22 8.39e-08 GO:0044424 intracellular part
1.91 1.26e-07 GO:0005829 cytosol
1.40 1.52e-05 GO:0005634 nucleus
4.07 2.60e-04 GO:0070161 anchoring junction
4.24 3.10e-04 GO:0005912 adherens junction
9.57 3.16e-04 GO:0042641 actomyosin
5.18 3.19e-04 GO:0005925 focal adhesion
4.93 5.62e-04 GO:0005924 cell-substrate adherens junction
1.24 8.55e-04 GO:0005737 cytoplasm
4.75 8.64e-04 GO:0030055 cell-substrate junction
3.04 1.03e-03 GO:0015629 actin cytoskeleton
1.20 1.19e-03 GO:0043229 intracellular organelle
1.19 1.43e-03 GO:0043226 organelle
1.21 4.28e-03 GO:0043231 intracellular membrane-bounded organelle
1.21 4.72e-03 GO:0043227 membrane-bounded organelle
3.10 5.77e-03 GO:0016323 basolateral plasma membrane
7.08 1.21e-02 GO:0000118 histone deacetylase complex
8.46 1.49e-02 GO:0001725 stress fiber
7.89 2.25e-02 GO:0032432 actin filament bundle
1.62 3.93e-02 GO:0005856 cytoskeleton
4.44 4.67e-02 GO:0009898 internal side of plasma membrane

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
1.40 4.82e-09 GO:0005515 protein binding
1.17 2.19e-05 GO:0005488 binding
2.21 2.26e-05 GO:0001071 nucleic acid binding transcription factor activity
2.21 2.26e-05 GO:0003700 sequence-specific DNA binding transcription factor activity
2.07 2.79e-04 GO:0030528 transcription regulator activity
2.27 1.06e-03 GO:0043565 sequence-specific DNA binding
3.46 3.15e-03 GO:0010843 promoter binding
3.32 5.36e-03 GO:0000975 regulatory region DNA binding
3.32 5.36e-03 GO:0001067 regulatory region nucleic acid binding
3.32 5.36e-03 GO:0044212 transcription regulatory region DNA binding
3.01 6.94e-03 GO:0005096 GTPase activator activity
2.30 7.32e-03 GO:0008092 cytoskeletal protein binding
2.40 8.99e-03 GO:0030695 GTPase regulator activity
1.54 9.44e-03 GO:0003677 DNA binding
1.90 1.37e-02 GO:0030234 enzyme regulator activity
2.34 1.43e-02 GO:0060589 nucleoside-triphosphatase regulator activity
2.76 1.48e-02 GO:0008134 transcription factor binding
1.95 4.48e-02 GO:0019899 enzyme binding