Motif ID: LHX3,4.p2

Z-value: 1.922


Transcription factors associated with LHX3,4.p2:

Gene SymbolEntrez IDGene Name
LHX3 8022 LIM homeobox 3
LHX4 89884 LIM homeobox 4

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
LHX4hg19_v1_chr1_+_180199432_1801994410.251.7e-01Click!
LHX3hg19_v1_chr9_-_139094886_1390950900.241.9e-01Click!


Activity profile for motif LHX3,4.p2.

activity profile for motif LHX3,4.p2


Sorted Z-values histogram for motif LHX3,4.p2

Sorted Z-values for motif LHX3,4.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of LHX3,4.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr19_-_51920841 7.898 NM_001171156
NM_001171157
NM_001171158
NM_001171159
NM_001171160
NM_001171161
NM_033130
 SIGLEC10






sialic acid binding Ig-like lectin 10






chr12_-_10282680 7.206 NM_022570
NM_197947
NM_197948
NM_197949
NM_197950
NM_197954
 CLEC7A





C-type lectin domain family 7, member A





chr1_+_198608216 6.714 PTPRC
protein tyrosine phosphatase, receptor type, C
chrX_+_107288199 6.552 NM_001170553
NM_182607
 VSIG1

V-set and immunoglobulin domain containing 1

chr1_+_155853546 6.344 SYT11
synaptotagmin XI
chr3_-_57234279 6.179 NM_003865
 HESX1
HESX homeobox 1
chr1_+_159259503 6.009 NM_002001
 FCER1A
Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
chr13_-_46425756 5.932 NM_198849
 SIAH3
seven in absentia homolog 3 (Drosophila)
chr5_+_175108463 5.339 NM_022304
 HRH2
histamine receptor H2
chr6_+_12717036 4.902 NM_001242648
NM_030948
 PHACTR1

phosphatase and actin regulator 1

chr1_+_117544371 4.861 NM_004258
 CD101
CD101 molecule
chr13_-_99910548 4.658 NM_001098200
NM_005292
 GPR18

G protein-coupled receptor 18

chr3_-_157221362 4.582 NM_001167915
NM_001167916
 VEPH1

ventricular zone expressed PH domain homolog 1 (zebrafish)

chr2_+_162272800 4.529 TBR1
T-box, brain, 1
chr12_+_8666135 4.463 NM_080387
 CLEC4D
C-type lectin domain family 4, member D
chr8_-_108510094 4.387 NM_001146
NM_001199859
 ANGPT1

angiopoietin 1

chr11_-_71524890 4.244 LOC285407
asparagine-linked glycosylation 1 homolog pseudogene
chr12_+_9980076 4.230 NM_016523
 KLRF1
killer cell lectin-like receptor subfamily F, member 1
chrX_-_102531673 4.226 NM_001012979
 TCEAL5
transcription elongation factor A (SII)-like 5
chr16_+_12058963 4.184 NM_001192
 TNFRSF17
tumor necrosis factor receptor superfamily, member 17

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 6 of 6 entries
Enrichment   P-value GO Accession GO Term
22.52 1.91e-02 GO:0050854 regulation of antigen receptor-mediated signaling pathway
3.23 1.08e-04 GO:0006955 immune response
2.68 4.91e-02 GO:0002682 regulation of immune system process
2.66 7.56e-05 GO:0002376 immune system process
2.63 1.78e-02 GO:0006952 defense response
1.96 2.43e-02 GO:0048583 regulation of response to stimulus

Gene overrepresentation in compartment category:

Showing 1 to 2 of 2 entries
Enrichment   P-value GO Accession GO Term
1.47 3.41e-02 GO:0071944 cell periphery
1.47 3.94e-02 GO:0005886 plasma membrane

Gene overrepresentation in function category:

Showing 1 to 2 of 2 entries
Enrichment   P-value GO Accession GO Term
5.34 4.90e-04 GO:0005529 sugar binding
3.24 2.06e-02 GO:0030246 carbohydrate binding