Motif ID: MAFB.p2

Z-value: 3.392


Transcription factors associated with MAFB.p2:

Gene SymbolEntrez IDGene Name
MAFB 9935 v-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian)

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
MAFBhg19_v1_chr20_-_39317875_393178800.144.3e-01Click!


Activity profile for motif MAFB.p2.

activity profile for motif MAFB.p2


Sorted Z-values histogram for motif MAFB.p2

Sorted Z-values for motif MAFB.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of MAFB.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_+_123295860 5.586 NM_207163
LMOD2
leiomodin 2 (cardiac)
chr14_-_60337350 5.345 NM_021136
RTN1
reticulon 1
chr3_-_10547340 5.304 ATP2B2
ATPase, Ca++ transporting, plasma membrane 2
chr22_+_29876180 5.201 NM_021076
NEFH
neurofilament, heavy polypeptide
chr6_+_124125068 5.049 NM_001040214
NM_153355
NKAIN2

Na+/K+ transporting ATPase interacting 2

chr19_+_4791727 4.692 NM_018708
FEM1A
fem-1 homolog a (C. elegans)
chr19_+_4791757 4.575 FEM1A
fem-1 homolog a (C. elegans)
chr16_+_6069094 4.541 NM_001142333
NM_018723
RBFOX1

RNA binding protein, fox-1 homolog (C. elegans) 1

chr19_+_4791756 4.477 FEM1A
fem-1 homolog a (C. elegans)
chr8_+_24771276 4.401 NEFM
neurofilament, medium polypeptide
chr6_+_99282597 4.375 POU3F2
POU class 3 homeobox 2
chrX_+_21392396 4.108 NM_001168647
NM_001168648
NM_001168649
NM_014927
CNKSR2



connector enhancer of kinase suppressor of Ras 2



chr3_-_10547221 3.978 ATP2B2
ATPase, Ca++ transporting, plasma membrane 2
chrX_+_37545008 3.879 NM_021083
XK
X-linked Kx blood group (McLeod syndrome)
chr2_-_11810254 3.701 NM_012344
NTSR2
neurotensin receptor 2
chr8_+_24771268 3.659 NM_005382
NEFM
neurofilament, medium polypeptide
chr6_+_150464156 3.618 NM_030949
PPP1R14C
protein phosphatase 1, regulatory (inhibitor) subunit 14C
chr8_-_75233461 3.481 NM_020647
JPH1
junctophilin 1
chr3_-_187463227 3.450 BCL6
B-cell CLL/lymphoma 6
chr5_-_36151953 3.401 NM_001007527
LMBRD2
LMBR1 domain containing 2
chr1_-_165414499 3.260 NM_006917
RXRG
retinoid X receptor, gamma
chr17_-_50235670 3.218 CA10
carbonic anhydrase X
chr2_-_220173693 3.158 NM_001199764
PTPRN
protein tyrosine phosphatase, receptor type, N
chr9_-_101470836 3.151 NM_005458
GABBR2
gamma-aminobutyric acid (GABA) B receptor, 2
chr14_+_90863365 3.075 CALM1
calmodulin 1 (phosphorylase kinase, delta)
chr22_+_26565424 3.064 NM_001184773
NM_001184774
NM_001184775
NM_001184776
NM_001184777
NM_021115
SEZ6L





seizure related 6 homolog (mouse)-like





chr17_-_7518124 3.044 NM_004860
FXR2
fragile X mental retardation, autosomal homolog 2
chr11_+_123431036 3.024 GRAMD1B
GRAM domain containing 1B
chr8_-_125384916 3.019 NM_194291
TMEM65
transmembrane protein 65
chr3_-_10547267 3.015 NM_001001331
NM_001683
ATP2B2

ATPase, Ca++ transporting, plasma membrane 2

chr7_-_137531585 3.008 NM_004717
DGKI
diacylglycerol kinase, iota
chr12_-_70083055 2.977 NM_152439
BEST3
bestrophin 3
chrX_+_49126480 2.962 PPP1R3F
protein phosphatase 1, regulatory subunit 3F
chr22_+_26565623 2.949 SEZ6L
seizure related 6 homolog (mouse)-like
chr20_-_32031425 2.909 NM_003098
SNTA1
syntrophin, alpha 1 (dystrophin-associated protein A1, 59kDa, acidic component)
chr19_+_36359346 2.905 NM_001024807
NM_005166
APLP1

amyloid beta (A4) precursor-like protein 1

chr11_-_77122877 2.871 PAK1
p21 protein (Cdc42/Rac)-activated kinase 1
chr5_-_147162175 2.849 JAKMIP2
janus kinase and microtubule interacting protein 2
chr1_-_102462371 2.845 OLFM3
olfactomedin 3
chr3_-_187463474 2.836 NM_001706
BCL6
B-cell CLL/lymphoma 6
chr17_+_44101549 2.824 MAPT
microtubule-associated protein tau
chr5_-_78809658 2.812 NM_004272
HOMER1
homer homolog 1 (Drosophila)
chrX_-_154688260 2.806 NM_001007523
NM_001007524
NM_012151
F8A2
F8A3
F8A1
coagulation factor VIII-associated 2
coagulation factor VIII-associated 3
coagulation factor VIII-associated 1
chrX_+_68725077 2.800 NM_015686
FAM155B
family with sequence similarity 155, member B
chr4_-_168155691 2.770 SPOCK3
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
chr8_+_85095501 2.721 NM_173848
RALYL
RALY RNA binding protein-like
chr18_-_35145603 2.690 CELF4
CUGBP, Elav-like family member 4
chr14_-_65346554 2.652 SPTB
spectrin, beta, erythrocytic
chr8_+_85095702 2.651 RALYL
RALY RNA binding protein-like
chrX_+_49126326 2.649 PPP1R3F
protein phosphatase 1, regulatory subunit 3F
chr1_+_90286595 2.611 LRRC8D
leucine rich repeat containing 8 family, member D
chr2_-_193059249 2.609 TMEFF2
transmembrane protein with EGF-like and two follistatin-like domains 2
chr8_+_85095452 2.606 NM_001100392
NM_001100393
RALYL

RALY RNA binding protein-like

chrX_+_49126299 2.601 NM_001184745
NM_033215
PPP1R3F

protein phosphatase 1, regulatory subunit 3F

chr5_-_147162251 2.598 NM_014790
JAKMIP2
janus kinase and microtubule interacting protein 2
chr17_-_39296702 2.596 NM_030976
KRTAP4-6
keratin associated protein 4-6
chr20_+_1246959 2.572 NM_014723
SNPH
syntaphilin
chr11_-_67188614 2.566 PPP1CA
protein phosphatase 1, catalytic subunit, alpha isozyme
chr1_-_109935869 2.535 NM_001205228
SORT1
sortilin 1
chr10_-_115423640 2.527 NM_006175
NM_198060
NRAP

nebulin-related anchoring protein

chr14_-_91526731 2.503


chr12_-_109458844 2.494 NM_018711
SVOP
SV2 related protein homolog (rat)
chr1_+_177140530 2.484 NM_021165
FAM5B
family with sequence similarity 5, member B
chr5_-_146258143 2.479 NM_004576
NM_181675
NM_001127381
PPP2R2B


protein phosphatase 2, regulatory subunit B, beta


chr1_+_228395740 2.465 NM_001098623
NM_052843
OBSCN

obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF

chr2_+_198669316 2.465 NM_006226
PLCL1
phospholipase C-like 1
chr6_+_147524866 2.440 STXBP5
syntaxin binding protein 5 (tomosyn)
chr14_-_70655589 2.438 NM_033262
NM_058240
NM_182932
NM_183002
SLC8A3



solute carrier family 8 (sodium/calcium exchanger), member 3



chr11_-_35440514 2.435 SLC1A2
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr8_-_92053043 2.427 NM_018710
TMEM55A
transmembrane protein 55A
chr19_-_13617037 2.409 NM_000068
NM_001127221
NM_001127222
NM_001174080
NM_023035
CACNA1A




calcium channel, voltage-dependent, P/Q type, alpha 1A subunit




chr21_+_34398210 2.408 NM_005806
OLIG2
oligodendrocyte lineage transcription factor 2
chr3_+_85008031 2.387 NM_001167674
NM_001167675
CADM2

cell adhesion molecule 2

chr7_-_143059696 2.365 NM_001031690
FAM131B
family with sequence similarity 131, member B
chr2_+_79740171 2.363 CTNNA2
catenin (cadherin-associated protein), alpha 2
chr11_+_109292874 2.348 C11orf87
chromosome 11 open reading frame 87
chr16_+_7382750 2.333 NM_145891
NM_145892
NM_145893
RBFOX1


RNA binding protein, fox-1 homolog (C. elegans) 1


chr19_+_1450117 2.332 NM_005883
APC2
adenomatosis polyposis coli 2
chrX_-_46618596 2.307 SLC9A7
solute carrier family 9 (sodium/hydrogen exchanger), member 7
chr4_-_168155576 2.288 NM_001204353
SPOCK3
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
chr5_-_147162264 2.264 JAKMIP2
janus kinase and microtubule interacting protein 2
chr4_-_168155732 2.253 NM_001040159
NM_001204352
NM_001204354
NM_001204355
NM_001204356
NM_001204358
NM_001251967
NM_016950
SPOCK3







sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3







chr1_-_241520384 2.250 RGS7
regulator of G-protein signaling 7
chr11_-_61348290 2.243 NM_001252065
NM_004200
SYT7

synaptotagmin VII

chr5_+_6449114 2.217 UBE2QL1
ubiquitin-conjugating enzyme E2Q family-like 1
chr12_-_111021122 2.203 PPTC7
PTC7 protein phosphatase homolog (S. cerevisiae)
chr5_-_27038650 2.200 NM_016279
CDH9
cadherin 9, type 2 (T1-cadherin)
chr2_+_79740059 2.193 NM_001164883
NM_004389
CTNNA2

catenin (cadherin-associated protein), alpha 2

chr16_-_12009775 2.193 GSPT1
G1 to S phase transition 1
chr6_-_84418492 2.168 SNAP91
synaptosomal-associated protein, 91kDa homolog (mouse)
chr10_-_133109808 2.150 TCERG1L
transcription elongation regulator 1-like
chr12_+_125478234 2.147 BRI3BP
BRI3 binding protein
chr1_-_31712733 2.146 NM_024522
NKAIN1
Na+/K+ transporting ATPase interacting 1
chr1_-_102462789 2.130 NM_058170
OLFM3
olfactomedin 3
chr22_+_26565454 2.126 SEZ6L
seizure related 6 homolog (mouse)-like
chr16_-_12009568 2.117


chr17_-_7517849 2.107 FXR2
fragile X mental retardation, autosomal homolog 2
chr6_+_150070844 2.093 PCMT1
protein-L-isoaspartate (D-aspartate) O-methyltransferase
chr1_+_110527399 2.079 AHCYL1
adenosylhomocysteinase-like 1
chr13_-_26625164 2.078 NM_001007538
SHISA2
shisa homolog 2 (Xenopus laevis)
chr1_-_31845818 2.071 NM_004102
FABP3
fatty acid binding protein 3, muscle and heart (mammary-derived growth inhibitor)
chr5_-_147162056 2.055 JAKMIP2
janus kinase and microtubule interacting protein 2
chr10_-_75410778 2.049 NM_024875
SYNPO2L
synaptopodin 2-like
chr2_-_179672056 2.043 NM_003319
NM_133378
NM_133379
NM_133432
NM_133437
TTN




titin




chr1_-_32403888 2.041 PTP4A2
protein tyrosine phosphatase type IVA, member 2
chr17_+_40610875 2.028 ATP6V0A1
ATPase, H+ transporting, lysosomal V0 subunit a1
chr3_-_119812512 2.027 GSK3B
glycogen synthase kinase 3 beta
chr11_-_35441099 2.024 NM_004171
SLC1A2
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr5_-_131347249 2.024 NM_001009185
NM_001205247
NM_015256
ACSL6


acyl-CoA synthetase long-chain family member 6


chr3_-_62860561 2.012


chr13_+_96743092 1.993 NM_153456
HS6ST3
heparan sulfate 6-O-sulfotransferase 3
chr1_+_109792640 1.990 NM_001408
CELSR2
cadherin, EGF LAG seven-pass G-type receptor 2 (flamingo homolog, Drosophila)
chr20_-_35374530 1.990 NM_022477
NM_032013
NDRG3

NDRG family member 3

chr10_+_26505235 1.988 NM_000818
NM_001134366
GAD2

glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)

chr6_+_71377471 1.985 NM_001044305
NM_021940
SMAP1

small ArfGAP 1

chr17_+_40610897 1.977 ATP6V0A1
ATPase, H+ transporting, lysosomal V0 subunit a1
chr1_+_110527307 1.976 AHCYL1
adenosylhomocysteinase-like 1
chr14_-_60097531 1.974 NM_206852
RTN1
reticulon 1
chr1_+_90286469 1.967 NM_001134479
LRRC8D
leucine rich repeat containing 8 family, member D
chr9_-_93405066 1.956 NM_017594
DIRAS2
DIRAS family, GTP-binding RAS-like 2
chr2_-_179659680 1.928 TTN
titin
chr12_-_58132028 1.924 NM_001122772
AGAP2
ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
chr17_-_56065474 1.921 VEZF1
vascular endothelial zinc finger 1
chr3_+_49591897 1.918 NM_003458
BSN
bassoon (presynaptic cytomatrix protein)
chr10_-_75634219 1.909 NM_001204492
NM_001222
NM_172169
NM_172170
NM_172171
NM_172173
CAMK2G





calcium/calmodulin-dependent protein kinase II gamma





chr6_+_150070856 1.908 PCMT1
protein-L-isoaspartate (D-aspartate) O-methyltransferase
chr1_-_166135978 1.903


chr1_-_32403975 1.902 NM_080391
PTP4A2
protein tyrosine phosphatase type IVA, member 2
chr1_-_182360400 1.896 NM_001033056
GLUL
glutamate-ammonia ligase
chr3_+_160473995 1.884 NM_139245
PPM1L
protein phosphatase, Mg2+/Mn2+ dependent, 1L
chr4_-_44450509 1.884 KCTD8
potassium channel tetramerisation domain containing 8
chr1_+_110082493 1.882 NM_031936
GPR61
G protein-coupled receptor 61
chr5_-_138730884 1.882 NM_001161546
C5orf65
chromosome 5 open reading frame 65
chr3_-_131753757 1.877 NM_130808
CPNE4
copine IV
chr17_+_40610905 1.875 ATP6V0A1
ATPase, H+ transporting, lysosomal V0 subunit a1
chr1_+_110527418 1.872 AHCYL1
adenosylhomocysteinase-like 1
chr5_+_137774897 1.864 REEP2
receptor accessory protein 2
chr6_+_150070818 1.845 NM_001252049
NM_001252050
NM_001252051
NM_001252052
NM_001252053
NM_005389
PCMT1





protein-L-isoaspartate (D-aspartate) O-methyltransferase





chr5_-_141993691 1.840 NM_033137
FGF1
fibroblast growth factor 1 (acidic)
chr16_+_87636492 1.837 NM_020655
JPH3
junctophilin 3
chr17_+_40610857 1.835 NM_001130020
NM_001130021
NM_005177
ATP6V0A1


ATPase, H+ transporting, lysosomal V0 subunit a1


chrX_+_72223351 1.829 NM_001042506
PABPC1L2B
poly(A) binding protein, cytoplasmic 1-like 2B
chr2_+_191745568 1.826 GLS
glutaminase
chr2_-_74601653 1.825 NM_001135041
NM_023019
DCTN1

dynactin 1

chr3_-_142682177 1.819 NM_198504
PAQR9
progestin and adipoQ receptor family member IX
chr17_+_40610940 1.818 ATP6V0A1
ATPase, H+ transporting, lysosomal V0 subunit a1
chr1_-_177133818 1.818 ASTN1
astrotactin 1
chr2_+_207308280 1.809 NM_003812
ADAM23
ADAM metallopeptidase domain 23
chr11_-_119252267 1.808 USP2
ubiquitin specific peptidase 2
chr7_+_95401817 1.803 NM_001135556
NM_001135557
NM_004411
DYNC1I1


dynein, cytoplasmic 1, intermediate chain 1


chr3_+_10857867 1.801 NM_014229
SLC6A11
solute carrier family 6 (neurotransmitter transporter, GABA), member 11
chr14_+_29236882 1.799 FOXG1
forkhead box G1
chr11_-_119252364 1.795 NM_001243759
NM_004205
USP2

ubiquitin specific peptidase 2

chr1_+_110527432 1.784 AHCYL1
adenosylhomocysteinase-like 1
chr3_+_111718006 1.778 NM_001008273
TAGLN3
transgelin 3
chr6_+_72596699 1.770 RIMS1
regulating synaptic membrane exocytosis 1
chr5_+_65017993 1.769 NM_020726
NLN
neurolysin (metallopeptidase M3 family)
chr1_+_44870926 1.768 NM_018150
RNF220
ring finger protein 220
chr1_-_144931967 1.759 NM_001002811
PDE4DIP
phosphodiesterase 4D interacting protein
chrX_+_154114609 1.757 NM_001007523
NM_001007524
NM_012151
F8A2
F8A3
F8A1
coagulation factor VIII-associated 2
coagulation factor VIII-associated 3
coagulation factor VIII-associated 1
chr6_+_99282579 1.755 NM_005604
POU3F2
POU class 3 homeobox 2
chr16_-_28074776 1.754 NM_001109763
GSG1L
GSG1-like
chr17_+_40610899 1.750 ATP6V0A1
ATPase, H+ transporting, lysosomal V0 subunit a1
chr1_+_87170222 1.749 NM_001206651
NM_001206652
NM_001206653
NM_016009
SH3GLB1



SH3-domain GRB2-like endophilin B1



chr11_+_109292837 1.746 NM_207645
C11orf87
chromosome 11 open reading frame 87
chr19_-_59069747 1.745 UBE2M
ubiquitin-conjugating enzyme E2M
chr6_+_73331808 1.731 KCNQ5
potassium voltage-gated channel, KQT-like subfamily, member 5
chr10_+_105344714 1.730 NEURL
neuralized homolog (Drosophila)
chr1_-_6662681 1.729 KLHL21
kelch-like 21 (Drosophila)
chr2_-_178937472 1.729 NM_016953
PDE11A
phosphodiesterase 11A
chr2_+_170683900 1.723 NM_172070
UBR3
ubiquitin protein ligase E3 component n-recognin 3 (putative)
chr17_-_42988797 1.721 GFAP
glial fibrillary acidic protein
chr9_+_140033588 1.720 NM_000832
NM_001185090
NM_001185091
NM_007327
NM_021569
GRIN1




glutamate receptor, ionotropic, N-methyl D-aspartate 1




chr2_+_200776025 1.708 C2orf69
chromosome 2 open reading frame 69
chr18_-_40695483 1.700 NM_002930
RIT2
Ras-like without CAAX 2
chrX_+_103411235 1.694 FAM199X
family with sequence similarity 199, X-linked
chr2_+_219824346 1.693 NM_003936
CDK5R2
cyclin-dependent kinase 5, regulatory subunit 2 (p39)
chr6_+_72596405 1.691 RIMS1
regulating synaptic membrane exocytosis 1
chr14_-_91526912 1.690 NM_004755
NM_182398
RPS6KA5

ribosomal protein S6 kinase, 90kDa, polypeptide 5

chr17_-_74236272 1.688 NM_052916
RNF157
ring finger protein 157
chr1_+_160051343 1.680 NM_004983
KCNJ9
potassium inwardly-rectifying channel, subfamily J, member 9
chr11_+_17757494 1.675 NM_001112741
NM_004976
KCNC1

potassium voltage-gated channel, Shaw-related subfamily, member 1

chr17_+_40610915 1.670 ATP6V0A1
ATPase, H+ transporting, lysosomal V0 subunit a1
chr17_+_43972014 1.670 MAPT
microtubule-associated protein tau
chr11_+_107462073 1.656 ELMOD1
ELMO/CED-12 domain containing 1
chr14_+_102829298 1.654 NM_001172631
NM_014844
TECPR2

tectonin beta-propeller repeat containing 2

chr3_+_181417387 1.653 SOX2-OT
SOX2 overlapping transcript (non-protein coding)
chr17_+_43971998 1.647 MAPT
microtubule-associated protein tau
chr14_-_31676826 1.644


chr20_-_21494663 1.639 NM_002509
NKX2-2
NK2 homeobox 2
chr1_+_50574601 1.638 ELAVL4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr19_+_35521591 1.632 NM_001037
NM_199037
SCN1B

sodium channel, voltage-gated, type I, beta

chr6_+_32936375 1.628


chr2_+_200776006 1.624 C2orf69
chromosome 2 open reading frame 69
chr8_+_56015013 1.622 NM_052898
XKR4
XK, Kell blood group complex subunit-related family, member 4
chr2_-_55277421 1.619 RTN4
reticulon 4
chr2_+_44396061 1.615 PPM1B
protein phosphatase, Mg2+/Mn2+ dependent, 1B
chr10_-_133109983 1.614 NM_174937
TCERG1L
transcription elongation regulator 1-like
chr11_+_107461955 1.611 ELMOD1
ELMO/CED-12 domain containing 1
chrX_+_37430821 1.609 NM_001170331
NM_198511
LANCL3

LanC lantibiotic synthetase component C-like 3 (bacterial)


Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
4.92 1.07e-14 GO:0019226 transmission of nerve impulse
4.92 1.07e-14 GO:0035637 multicellular organismal signaling
5.00 2.62e-13 GO:0007268 synaptic transmission
2.73 9.05e-12 GO:0007399 nervous system development
3.21 2.40e-08 GO:0007267 cell-cell signaling
2.71 4.54e-07 GO:0007154 cell communication
2.81 5.61e-07 GO:0022008 neurogenesis
2.85 1.00e-06 GO:0048699 generation of neurons
1.80 1.77e-05 GO:0048731 system development
1.51 2.38e-05 GO:0032501 multicellular organismal process
9.16 2.95e-05 GO:0007269 neurotransmitter secretion
1.71 7.08e-05 GO:0048856 anatomical structure development
7.15 1.20e-04 GO:0001505 regulation of neurotransmitter levels
1.65 1.54e-04 GO:0007275 multicellular organismal development
2.76 1.58e-04 GO:0030182 neuron differentiation
1.86 5.31e-04 GO:0030154 cell differentiation
2.41 5.36e-04 GO:0048468 cell development
1.58 5.55e-04 GO:0032502 developmental process
6.17 6.21e-04 GO:0006836 neurotransmitter transport
1.84 6.56e-04 GO:0048869 cellular developmental process
5.94 9.45e-04 GO:0003001 generation of a signal involved in cell-cell signaling
5.94 9.45e-04 GO:0023061 signal release
3.88 2.37e-03 GO:0050767 regulation of neurogenesis
1.53 3.61e-03 GO:0023052 signaling
4.14 4.26e-03 GO:0045664 regulation of neuron differentiation
1.99 4.85e-03 GO:0050877 neurological system process
1.55 4.93e-03 GO:0051179 localization
52.45 7.93e-03 GO:0021529 spinal cord oligodendrocyte cell differentiation
52.45 7.93e-03 GO:0021530 spinal cord oligodendrocyte cell fate specification
52.45 7.93e-03 GO:0021778 oligodendrocyte cell fate specification
52.45 7.93e-03 GO:0021780 glial cell fate specification
3.45 1.17e-02 GO:0051960 regulation of nervous system development
3.45 1.17e-02 GO:0061061 muscle structure development
3.25 1.44e-02 GO:0032940 secretion by cell
1.57 1.47e-02 GO:0051234 establishment of localization
3.21 1.66e-02 GO:0060284 regulation of cell development
4.89 1.81e-02 GO:0014706 striated muscle tissue development
1.80 2.10e-02 GO:0003008 system process
10.49 2.12e-02 GO:0021515 cell differentiation in spinal cord
6.77 2.53e-02 GO:0032409 regulation of transporter activity
2.62 3.08e-02 GO:0007417 central nervous system development
39.34 3.13e-02 GO:0021779 oligodendrocyte cell fate commitment
9.84 3.14e-02 GO:0048489 synaptic vesicle transport
4.48 4.18e-02 GO:0060537 muscle tissue development

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
4.33 7.59e-10 GO:0045202 synapse
4.56 6.84e-08 GO:0044456 synapse part
3.24 2.22e-07 GO:0030054 cell junction
6.63 1.88e-04 GO:0008021 synaptic vesicle
1.59 1.63e-03 GO:0043234 protein complex
4.24 3.14e-03 GO:0030136 clathrin-coated vesicle
8.16 5.04e-03 GO:0030672 synaptic vesicle membrane
3.73 6.23e-03 GO:0030135 coated vesicle
8.51 1.57e-02 GO:0042734 presynaptic membrane
7.68 2.84e-02 GO:0008287 protein serine/threonine phosphatase complex
4.27 2.97e-02 GO:0043292 contractile fiber
3.05 3.22e-02 GO:0030659 cytoplasmic vesicle membrane
2.60 3.52e-02 GO:0043005 neuron projection
3.28 4.43e-02 GO:0034702 ion channel complex
2.95 4.69e-02 GO:0012506 vesicle membrane
1.38 4.84e-02 GO:0005886 plasma membrane

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
5.66 1.72e-05 GO:0005516 calmodulin binding
2.75 5.49e-04 GO:0008092 cytoskeletal protein binding
52.45 1.81e-03 GO:0004351 glutamate decarboxylase activity
39.34 7.13e-03 GO:0050321 tau-protein kinase activity
3.18 1.28e-02 GO:0005261 cation channel activity
5.91 1.56e-02 GO:0005200 structural constituent of cytoskeleton
2.63 2.22e-02 GO:0015267 channel activity
2.16 2.28e-02 GO:0015075 ion transmembrane transporter activity
2.63 2.29e-02 GO:0022803 passive transmembrane transporter activity
2.35 2.59e-02 GO:0008324 cation transmembrane transporter activity
2.84 3.01e-02 GO:0003779 actin binding
1.85 3.20e-02 GO:0005215 transporter activity
2.62 3.56e-02 GO:0005216 ion channel activity
9.71 3.66e-02 GO:0019905 syntaxin binding
7.32 4.04e-02 GO:0008307 structural constituent of muscle
2.58 4.35e-02 GO:0022838 substrate-specific channel activity