Motif ID: MAFB.p2

Z-value: 3.392


Transcription factors associated with MAFB.p2:

Gene SymbolEntrez IDGene Name
MAFB 9935 v-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian)

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
MAFBhg19_v1_chr20_-_39317875_393178800.144.3e-01Click!


Activity profile for motif MAFB.p2.

activity profile for motif MAFB.p2


Sorted Z-values histogram for motif MAFB.p2

Sorted Z-values for motif MAFB.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of MAFB.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_+_123295860 5.586 NM_207163
 LMOD2
leiomodin 2 (cardiac)
chr14_-_60337350 5.345 NM_021136
 RTN1
reticulon 1
chr3_-_10547340 5.304 ATP2B2
ATPase, Ca++ transporting, plasma membrane 2
chr22_+_29876180 5.201 NM_021076
 NEFH
neurofilament, heavy polypeptide
chr6_+_124125068 5.049 NM_001040214
NM_153355
 NKAIN2

Na+/K+ transporting ATPase interacting 2

chr19_+_4791727 4.692 NM_018708
 FEM1A
fem-1 homolog a (C. elegans)
chr19_+_4791757 4.575 FEM1A
fem-1 homolog a (C. elegans)
chr16_+_6069094 4.541 NM_001142333
NM_018723
 RBFOX1

RNA binding protein, fox-1 homolog (C. elegans) 1

chr19_+_4791756 4.477 FEM1A
fem-1 homolog a (C. elegans)
chr8_+_24771276 4.401 NEFM
neurofilament, medium polypeptide
chr6_+_99282597 4.375 POU3F2
POU class 3 homeobox 2
chrX_+_21392396 4.108 NM_001168647
NM_001168648
NM_001168649
NM_014927
 CNKSR2



connector enhancer of kinase suppressor of Ras 2



chr3_-_10547221 3.978 ATP2B2
ATPase, Ca++ transporting, plasma membrane 2
chrX_+_37545008 3.879 NM_021083
 XK
X-linked Kx blood group (McLeod syndrome)
chr2_-_11810254 3.701 NM_012344
 NTSR2
neurotensin receptor 2
chr8_+_24771268 3.659 NM_005382
 NEFM
neurofilament, medium polypeptide
chr6_+_150464156 3.618 NM_030949
 PPP1R14C
protein phosphatase 1, regulatory (inhibitor) subunit 14C
chr8_-_75233461 3.481 NM_020647
 JPH1
junctophilin 1
chr3_-_187463227 3.450 BCL6
B-cell CLL/lymphoma 6
chr5_-_36151953 3.401 NM_001007527
 LMBRD2
LMBR1 domain containing 2

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 44 entries
Enrichment   P-value GO Accession GO Term
52.45 7.93e-03 GO:0021529 spinal cord oligodendrocyte cell differentiation
52.45 7.93e-03 GO:0021530 spinal cord oligodendrocyte cell fate specification
52.45 7.93e-03 GO:0021778 oligodendrocyte cell fate specification
52.45 7.93e-03 GO:0021780 glial cell fate specification
39.34 3.13e-02 GO:0021779 oligodendrocyte cell fate commitment
10.49 2.12e-02 GO:0021515 cell differentiation in spinal cord
9.84 3.14e-02 GO:0048489 synaptic vesicle transport
9.16 2.95e-05 GO:0007269 neurotransmitter secretion
7.15 1.20e-04 GO:0001505 regulation of neurotransmitter levels
6.77 2.53e-02 GO:0032409 regulation of transporter activity
6.17 6.21e-04 GO:0006836 neurotransmitter transport
5.94 9.45e-04 GO:0003001 generation of a signal involved in cell-cell signaling
5.94 9.45e-04 GO:0023061 signal release
5.00 2.62e-13 GO:0007268 synaptic transmission
4.92 1.07e-14 GO:0019226 transmission of nerve impulse
4.92 1.07e-14 GO:0035637 multicellular organismal signaling
4.89 1.81e-02 GO:0014706 striated muscle tissue development
4.48 4.18e-02 GO:0060537 muscle tissue development
4.14 4.26e-03 GO:0045664 regulation of neuron differentiation
3.88 2.37e-03 GO:0050767 regulation of neurogenesis

Gene overrepresentation in compartment category:

Showing 1 to 16 of 16 entries
Enrichment   P-value GO Accession GO Term
8.51 1.57e-02 GO:0042734 presynaptic membrane
8.16 5.04e-03 GO:0030672 synaptic vesicle membrane
7.68 2.84e-02 GO:0008287 protein serine/threonine phosphatase complex
6.63 1.88e-04 GO:0008021 synaptic vesicle
4.56 6.84e-08 GO:0044456 synapse part
4.33 7.59e-10 GO:0045202 synapse
4.27 2.97e-02 GO:0043292 contractile fiber
4.24 3.14e-03 GO:0030136 clathrin-coated vesicle
3.73 6.23e-03 GO:0030135 coated vesicle
3.28 4.43e-02 GO:0034702 ion channel complex
3.24 2.22e-07 GO:0030054 cell junction
3.05 3.22e-02 GO:0030659 cytoplasmic vesicle membrane
2.95 4.69e-02 GO:0012506 vesicle membrane
2.60 3.52e-02 GO:0043005 neuron projection
1.59 1.63e-03 GO:0043234 protein complex
1.38 4.84e-02 GO:0005886 plasma membrane

Gene overrepresentation in function category:

Showing 1 to 16 of 16 entries
Enrichment   P-value GO Accession GO Term
52.45 1.81e-03 GO:0004351 glutamate decarboxylase activity
39.34 7.13e-03 GO:0050321 tau-protein kinase activity
9.71 3.66e-02 GO:0019905 syntaxin binding
7.32 4.04e-02 GO:0008307 structural constituent of muscle
5.91 1.56e-02 GO:0005200 structural constituent of cytoskeleton
5.66 1.72e-05 GO:0005516 calmodulin binding
3.18 1.28e-02 GO:0005261 cation channel activity
2.84 3.01e-02 GO:0003779 actin binding
2.75 5.49e-04 GO:0008092 cytoskeletal protein binding
2.63 2.22e-02 GO:0015267 channel activity
2.63 2.29e-02 GO:0022803 passive transmembrane transporter activity
2.62 3.56e-02 GO:0005216 ion channel activity
2.58 4.35e-02 GO:0022838 substrate-specific channel activity
2.35 2.59e-02 GO:0008324 cation transmembrane transporter activity
2.16 2.28e-02 GO:0015075 ion transmembrane transporter activity
1.85 3.20e-02 GO:0005215 transporter activity