Motif ID: MSX1,2.p2

Z-value: 2.243


Transcription factors associated with MSX1,2.p2:

Gene SymbolEntrez IDGene Name
MSX1 4487 msh homeobox 1
MSX2 4488 msh homeobox 2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
MSX2hg19_v1_chr5_+_174151531_174151694-0.144.4e-01Click!
MSX1hg19_v1_chr4_+_4861371_48614260.048.4e-01Click!


Activity profile for motif MSX1,2.p2.

activity profile for motif MSX1,2.p2


Sorted Z-values histogram for motif MSX1,2.p2

Sorted Z-values for motif MSX1,2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of MSX1,2.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr14_-_65409445 22.010 NM_002083
 GPX2
glutathione peroxidase 2 (gastrointestinal)
chr9_-_116840551 16.911 AMBP
alpha-1-microglobulin/bikunin precursor
chr4_+_155484131 14.179 NM_001184741
NM_005141
 FGB

fibrinogen beta chain

chr9_-_116840460 13.407 AMBP
alpha-1-microglobulin/bikunin precursor
chr4_+_88896838 12.431 SPP1
secreted phosphoprotein 1
chr3_-_165555167 11.646 BCHE
butyrylcholinesterase
chr4_+_88896801 11.603 NM_000582
NM_001040058
NM_001040060
NM_001251829
NM_001251830
 SPP1




secreted phosphoprotein 1




chr10_-_74714479 11.378 NM_032562
 PLA2G12B
phospholipase A2, group XIIB
chr17_+_68071386 10.684 NM_018658
NM_170741
 KCNJ16

potassium inwardly-rectifying channel, subfamily J, member 16

chr3_+_186383770 10.517 NM_000412
 HRG
histidine-rich glycoprotein
chr4_+_88896868 10.437 SPP1
secreted phosphoprotein 1
chr9_-_116840604 10.384 AMBP
alpha-1-microglobulin/bikunin precursor
chr10_+_7745325 10.383 ITIH2
inter-alpha-trypsin inhibitor heavy chain 2
chr3_-_165555252 9.395 NM_000055
 BCHE
butyrylcholinesterase
chr4_+_88896899 8.629 SPP1
secreted phosphoprotein 1
chr10_+_7745354 8.591 ITIH2
inter-alpha-trypsin inhibitor heavy chain 2
chr10_-_74714563 8.222 PLA2G12B
phospholipase A2, group XIIB
chr19_-_14169970 8.003 NM_001145028
 PALM3
paralemmin 3
chr8_+_76452202 7.668 NM_004133
 HNF4G
hepatocyte nuclear factor 4, gamma
chr3_+_25470067 7.589 RARB
retinoic acid receptor, beta

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 2 of 2 entries
Enrichment   P-value GO Accession GO Term
19.16 3.35e-03 GO:0006956 complement activation
15.83 1.18e-03 GO:0072376 protein activation cascade

Gene overrepresentation in compartment category:

Showing 1 to 10 of 10 entries
Enrichment   P-value GO Accession GO Term
68.94 9.24e-04 GO:0005577 fibrinogen complex
18.57 9.22e-05 GO:0031983 vesicle lumen
16.76 1.34e-03 GO:0034774 secretory granule lumen
16.09 1.64e-03 GO:0060205 cytoplasmic membrane-bounded vesicle lumen
13.70 2.35e-02 GO:0031093 platelet alpha granule lumen
11.30 4.97e-02 GO:0031091 platelet alpha granule
5.64 2.87e-02 GO:0030141 stored secretory granule
4.11 1.60e-05 GO:0005615 extracellular space
3.66 1.07e-05 GO:0044421 extracellular region part
3.13 9.24e-09 GO:0005576 extracellular region

Nothing significant found in function category.