Motif ID: MTF1.p2

Z-value: 1.977


Transcription factors associated with MTF1.p2:

Gene SymbolEntrez IDGene Name
MTF1 4520 metal-regulatory transcription factor 1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
MTF1hg19_v1_chr1_-_38325224_38325292-0.451.1e-02Click!


Activity profile for motif MTF1.p2.

activity profile for motif MTF1.p2


Sorted Z-values histogram for motif MTF1.p2

Sorted Z-values for motif MTF1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of MTF1.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr16_-_56701904 6.753 NM_005950
 MT1G
metallothionein 1G
chr5_-_11904127 6.103 CTNND2
catenin (cadherin-associated protein), delta 2 (neural plakophilin-related arm-repeat protein)
chr6_+_56819706 5.460 NM_152731
 BEND6
BEN domain containing 6
chr5_-_11903964 5.242 NM_001332
 CTNND2
catenin (cadherin-associated protein), delta 2 (neural plakophilin-related arm-repeat protein)
chr2_+_231902194 4.864 NM_001144994
 C2orf72
chromosome 2 open reading frame 72
chr16_+_56666533 4.675 NM_176870
 MT1M
metallothionein 1M
chr15_-_29862926 4.611 NM_015307
 FAM189A1
family with sequence similarity 189, member A1
chr16_+_56703725 4.526 NM_005951
 MT1H
metallothionein 1H
chr2_+_14772839 4.366 FAM84A
family with sequence similarity 84, member A
chr10_-_43762366 3.958 NM_145313
 RASGEF1A
RasGEF domain family, member 1A
chr3_+_39851028 3.781 NM_015460
 MYRIP
myosin VIIA and Rab interacting protein
chr6_+_56819923 3.748 BEND6
BEN domain containing 6
chr20_-_55841090 3.697 BMP7
bone morphogenetic protein 7
chr16_+_12995454 3.688 NM_001145204
NM_001145205
 SHISA9

shisa homolog 9 (Xenopus laevis)

chr22_+_43808011 3.674 NM_001044370
 MPPED1
metallophosphoesterase domain containing 1
chr8_+_1711869 3.618 NM_018941
 CLN8
ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation)
chr16_+_58497548 3.583 NM_020465
 NDRG4
NDRG family member 4
chr7_-_44365019 3.513 NM_001220
NM_172078
NM_172079
NM_172080
NM_172081
NM_172082
NM_172083
NM_172084
 CAMK2B







calcium/calmodulin-dependent protein kinase II beta







chr8_-_26371387 3.364 NM_007257
 PNMA2
paraneoplastic antigen MA2
chr11_+_125774271 3.345 NM_013264
 DDX25
DEAD (Asp-Glu-Ala-Asp) box polypeptide 25

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 38 entries
Enrichment   P-value GO Accession GO Term
5.43 1.32e-04 GO:0030900 forebrain development
5.37 4.89e-02 GO:0051924 regulation of calcium ion transport
4.34 3.71e-08 GO:0007268 synaptic transmission
4.13 2.63e-08 GO:0019226 transmission of nerve impulse
4.13 2.63e-08 GO:0035637 multicellular organismal signaling
4.11 1.21e-05 GO:0007420 brain development
4.02 5.42e-08 GO:0007417 central nervous system development
3.16 7.80e-04 GO:0000904 cell morphogenesis involved in differentiation
3.14 4.35e-03 GO:0048667 cell morphogenesis involved in neuron differentiation
3.10 8.97e-03 GO:0007409 axonogenesis
3.09 2.41e-07 GO:0048699 generation of neurons
3.09 5.69e-03 GO:0048812 neuron projection morphogenesis
3.07 2.28e-03 GO:0031175 neuron projection development
3.06 1.10e-07 GO:0022008 neurogenesis
3.05 5.02e-06 GO:0007267 cell-cell signaling
2.99 7.69e-04 GO:0048666 neuron development
2.93 1.95e-12 GO:0007399 nervous system development
2.85 2.85e-04 GO:0030182 neuron differentiation
2.75 3.25e-02 GO:0048858 cell projection morphogenesis
2.73 3.70e-02 GO:0032990 cell part morphogenesis

Gene overrepresentation in compartment category:

Showing 1 to 19 of 19 entries
Enrichment   P-value GO Accession GO Term
9.55 3.47e-04 GO:0044309 neuron spine
8.71 2.97e-03 GO:0043197 dendritic spine
6.18 3.18e-03 GO:0008021 synaptic vesicle
5.43 9.00e-03 GO:0019717 synaptosome
4.76 1.43e-04 GO:0030425 dendrite
4.46 3.76e-09 GO:0045202 synapse
4.35 3.98e-06 GO:0044456 synapse part
3.74 7.08e-06 GO:0043005 neuron projection
3.06 2.19e-05 GO:0030054 cell junction
2.17 1.32e-08 GO:0044459 plasma membrane part
2.12 9.54e-04 GO:0005887 integral to plasma membrane
2.12 2.59e-02 GO:0042995 cell projection
2.08 1.51e-03 GO:0031226 intrinsic to plasma membrane
1.72 7.77e-08 GO:0005886 plasma membrane
1.71 8.57e-08 GO:0071944 cell periphery
1.48 1.78e-06 GO:0044425 membrane part
1.47 3.12e-09 GO:0016020 membrane
1.40 3.53e-03 GO:0016021 integral to membrane
1.38 9.12e-03 GO:0031224 intrinsic to membrane

Gene overrepresentation in function category:

Showing 1 to 18 of 18 entries
Enrichment   P-value GO Accession GO Term
35.81 1.21e-02 GO:0046870 cadmium ion binding
11.94 1.38e-02 GO:0030295 protein kinase activator activity
9.95 3.45e-02 GO:0019209 kinase activator activity
9.63 4.05e-02 GO:0005272 sodium channel activity
5.25 3.87e-02 GO:0019887 protein kinase regulator activity
5.05 1.33e-03 GO:0022843 voltage-gated cation channel activity
4.47 9.13e-04 GO:0005244 voltage-gated ion channel activity
4.47 9.13e-04 GO:0022832 voltage-gated channel activity
3.62 2.81e-03 GO:0005261 cation channel activity
3.57 9.51e-04 GO:0022836 gated channel activity
2.98 6.77e-03 GO:0005216 ion channel activity
2.96 1.71e-03 GO:0030695 GTPase regulator activity
2.93 8.39e-03 GO:0022838 substrate-specific channel activity
2.88 2.61e-03 GO:0060589 nucleoside-triphosphatase regulator activity
2.85 1.27e-02 GO:0015267 channel activity
2.84 1.31e-02 GO:0022803 passive transmembrane transporter activity
2.84 2.07e-02 GO:0008047 enzyme activator activity
2.14 1.16e-02 GO:0030234 enzyme regulator activity