Motif ID: MTF1.p2

Z-value: 1.977


Transcription factors associated with MTF1.p2:

Gene SymbolEntrez IDGene Name
MTF1 4520 metal-regulatory transcription factor 1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
MTF1hg19_v1_chr1_-_38325224_38325292-0.451.1e-02Click!


Activity profile for motif MTF1.p2.

activity profile for motif MTF1.p2


Sorted Z-values histogram for motif MTF1.p2

Sorted Z-values for motif MTF1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of MTF1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr16_-_56701904 6.753 NM_005950
MT1G
metallothionein 1G
chr5_-_11904127 6.103 CTNND2
catenin (cadherin-associated protein), delta 2 (neural plakophilin-related arm-repeat protein)
chr6_+_56819706 5.460 NM_152731
BEND6
BEN domain containing 6
chr5_-_11903964 5.242 NM_001332
CTNND2
catenin (cadherin-associated protein), delta 2 (neural plakophilin-related arm-repeat protein)
chr2_+_231902194 4.864 NM_001144994
C2orf72
chromosome 2 open reading frame 72
chr16_+_56666533 4.675 NM_176870
MT1M
metallothionein 1M
chr15_-_29862926 4.611 NM_015307
FAM189A1
family with sequence similarity 189, member A1
chr16_+_56703725 4.526 NM_005951
MT1H
metallothionein 1H
chr2_+_14772839 4.366 FAM84A
family with sequence similarity 84, member A
chr10_-_43762366 3.958 NM_145313
RASGEF1A
RasGEF domain family, member 1A
chr3_+_39851028 3.781 NM_015460
MYRIP
myosin VIIA and Rab interacting protein
chr6_+_56819923 3.748 BEND6
BEN domain containing 6
chr20_-_55841090 3.697 BMP7
bone morphogenetic protein 7
chr16_+_12995454 3.688 NM_001145204
NM_001145205
SHISA9

shisa homolog 9 (Xenopus laevis)

chr22_+_43808011 3.674 NM_001044370
MPPED1
metallophosphoesterase domain containing 1
chr8_+_1711869 3.618 NM_018941
CLN8
ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation)
chr16_+_58497548 3.583 NM_020465
NDRG4
NDRG family member 4
chr7_-_44365019 3.513 NM_001220
NM_172078
NM_172079
NM_172080
NM_172081
NM_172082
NM_172083
NM_172084
CAMK2B







calcium/calmodulin-dependent protein kinase II beta







chr8_-_26371387 3.364 NM_007257
PNMA2
paraneoplastic antigen MA2
chr11_+_125774271 3.345 NM_013264
DDX25
DEAD (Asp-Glu-Ala-Asp) box polypeptide 25
chr19_+_7660698 3.134 NM_001080429
NM_020902
CAMSAP3

calmodulin regulated spectrin-associated protein family, member 3

chr15_-_101459410 3.112


chr22_+_29279573 3.076 NM_001206998
ZNRF3
zinc and ring finger 3
chr3_-_183979074 3.000 NM_033259
CAMK2N2
calcium/calmodulin-dependent protein kinase II inhibitor 2
chr9_+_140772228 2.974 NM_000718
NM_001243812
CACNA1B

calcium channel, voltage-dependent, N type, alpha 1B subunit

chr6_-_99797530 2.892 NM_032511
C6orf168
chromosome 6 open reading frame 168
chr2_+_56411123 2.868 NM_001080433
CCDC85A
coiled-coil domain containing 85A
chr5_+_176237435 2.800 NM_133369
UNC5A
unc-5 homolog A (C. elegans)
chr5_+_92920592 2.777 NR2F1
NR2F2
nuclear receptor subfamily 2, group F, member 1
nuclear receptor subfamily 2, group F, member 2
chr16_+_56691854 2.774 NM_005949
MT1F
metallothionein 1F
chr1_+_104068312 2.698 RNPC3
RNA-binding region (RNP1, RRM) containing 3
chr2_+_219824346 2.682 NM_003936
CDK5R2
cyclin-dependent kinase 5, regulatory subunit 2 (p39)
chr7_+_45614081 2.677 NM_021116
ADCY1
adenylate cyclase 1 (brain)
chr4_-_109684053 2.667 NM_001146590
NM_001146627
NM_031279
AGXT2L1


alanine-glyoxylate aminotransferase 2-like 1


chr15_+_80696569 2.605 NM_014862
ARNT2
aryl-hydrocarbon receptor nuclear translocator 2
chr8_-_119964059 2.599 NM_002546
TNFRSF11B
tumor necrosis factor receptor superfamily, member 11b
chr20_-_55841671 2.565 NM_001719
BMP7
bone morphogenetic protein 7
chr16_+_58497628 2.548 NDRG4
NDRG family member 4
chr10_-_118501981 2.546 NM_025015
HSPA12A
heat shock 70kDa protein 12A
chr16_+_56672577 2.521 NM_005946
MT1A
metallothionein 1A
chr16_+_56659679 2.500 MT1E
metallothionein 1E
chr1_-_21949010 2.489 RAP1GAP
RAP1 GTPase activating protein
chr2_+_26915390 2.475 NM_002246
KCNK3
potassium channel, subfamily K, member 3
chr7_+_86274076 2.468 GRM3
glutamate receptor, metabotropic 3
chr2_+_14772809 2.457 NM_145175
FAM84A
family with sequence similarity 84, member A
chr11_+_66045645 2.421 NM_182553
CNIH2
cornichon homolog 2 (Drosophila)
chr17_-_36762105 2.419 NM_025248
SRCIN1
SRC kinase signaling inhibitor 1
chr19_-_49944613 2.412 NM_020309
SLC17A7
solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7
chr1_-_32229635 2.386 NM_001703
BAI2
brain-specific angiogenesis inhibitor 2
chr10_-_135238075 2.384 NM_001012508
SPRN
shadow of prion protein homolog (zebrafish)
chr14_-_25519076 2.384 NM_014178
STXBP6
syntaxin binding protein 6 (amisyn)
chr22_+_39853316 2.356 NM_002409
MGAT3
mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase
chr11_-_12030128 2.340 NM_001018057
DKK3
dickkopf 3 homolog (Xenopus laevis)
chr2_-_233792825 2.313 NM_001114090
NGEF
neuronal guanine nucleotide exchange factor
chr7_+_86273951 2.292 GRM3
glutamate receptor, metabotropic 3
chr4_+_30721865 2.286 NM_032456
NM_001173523
NM_002589
NM_032457
PCDH7



protocadherin 7



chr2_-_224903933 2.277 NM_001136528
NM_006216
SERPINE2

serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2

chr7_-_142985270 2.271


chr16_+_87636492 2.269 NM_020655
JPH3
junctophilin 3
chr13_+_98795410 2.261 NM_001001715
NM_005766
FARP1

FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)

chr16_+_58497993 2.240 NM_001130487
NDRG4
NDRG family member 4
chr10_+_134901408 2.238 NM_001083909
GPR123
G protein-coupled receptor 123
chr7_+_31092067 2.226 NM_001118
NM_001199635
NM_001199636
NM_001199637
ADCYAP1R1



adenylate cyclase activating polypeptide 1 (pituitary) receptor type I



chr4_+_150999412 2.210 NM_001040260
NM_001040261
DCLK2

doublecortin-like kinase 2

chr10_+_83635069 2.203 NM_001010848
NM_001165972
NRG3

neuregulin 3

chr10_+_124220990 2.189 NM_002775
HTRA1
HtrA serine peptidase 1
chr3_-_10749715 2.188 ATP2B2
ATPase, Ca++ transporting, plasma membrane 2
chr9_-_112083005 2.178 NM_018424
NM_019114
EPB41L4B

erythrocyte membrane protein band 4.1 like 4B

chr12_+_2162388 2.177 NM_000719
NM_001129827
NM_001129829
NM_001129830
NM_001129831
NM_001129832
NM_001129833
NM_001129834
NM_001129835
NM_001129836
NM_001129837
NM_001129838
NM_001129839
NM_001129840
NM_001129841
NM_001129842
NM_001129843
NM_001129844
NM_001129846
NM_001167623
NM_001167624
NM_001167625
NM_199460
CACNA1C






















calcium channel, voltage-dependent, L type, alpha 1C subunit






















chr9_-_93405066 2.154 NM_017594
DIRAS2
DIRAS family, GTP-binding RAS-like 2
chr9_+_34958320 2.138 KIAA1045
KIAA1045
chr8_+_136469557 2.136 NM_006558
KHDRBS3
KH domain containing, RNA binding, signal transduction associated 3
chr2_+_153191830 2.136 FMNL2
formin-like 2
chr22_+_29601685 2.114 NM_133455
EMID1
EMI domain containing 1
chr17_-_27053119 2.111 NM_138463
TLCD1
TLC domain containing 1
chr9_+_133320247 2.101 ASS1
argininosuccinate synthase 1
chr20_+_34742656 2.099 NM_012156
EPB41L1
erythrocyte membrane protein band 4.1-like 1
chr8_+_1712011 2.093 CLN8
ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation)
chr4_+_1795004 2.092 NM_000142
NM_001163213
NM_022965
FGFR3


fibroblast growth factor receptor 3


chrX_-_102319096 2.088 NM_018476
BEX1
brain expressed, X-linked 1
chr12_+_50451486 2.082 NM_001095
NM_020039
ACCN2

amiloride-sensitive cation channel 2, neuronal

chr10_+_116853118 2.056 NM_207303
ATRNL1
attractin-like 1
chr22_-_46933066 2.042 NM_014246
CELSR1
cadherin, EGF LAG seven-pass G-type receptor 1 (flamingo homolog, Drosophila)
chr2_-_107503517 2.035 NM_001142352
NM_032528
ST6GAL2

ST6 beta-galactosamide alpha-2,6-sialyltranferase 2

chr15_+_78632625 2.020 NM_004378
CRABP1
cellular retinoic acid binding protein 1
chrX_-_102319080 2.015 BEX1
brain expressed, X-linked 1
chr7_+_103969103 2.011 NM_199000
LHFPL3
lipoma HMGIC fusion partner-like 3
chr16_+_77822400 1.997 NM_020927
VAT1L
vesicle amine transport protein 1 homolog (T. californica)-like
chr2_+_242498118 1.993 NM_032515
BOK
BCL2-related ovarian killer
chr13_+_100633977 1.983 NM_007129
ZIC2
Zic family member 2
chr17_+_8924822 1.982 NM_004822
NTN1
netrin 1
chr4_-_77819001 1.968 NM_001029870
ANKRD56
ankyrin repeat domain 56
chr11_+_107461955 1.966 ELMOD1
ELMO/CED-12 domain containing 1
chr14_+_100111446 1.951 NM_001127258
NM_032425
HHIPL1

HHIP-like 1

chr1_-_241520384 1.920 RGS7
regulator of G-protein signaling 7
chr5_+_169931023 1.912 NM_001034837
NM_014592
KCNIP1

Kv channel interacting protein 1

chr9_-_112260529 1.908 NM_001145368
NM_002829
PTPN3

protein tyrosine phosphatase, non-receptor type 3

chr2_+_207308280 1.903 NM_003812
ADAM23
ADAM metallopeptidase domain 23
chr8_-_110704019 1.897 NM_001099743
NM_001099744
SYBU

syntabulin (syntaxin-interacting)

chr20_-_3154169 1.895 ProSAPiP1
ProSAPiP1 protein
chr3_+_184097860 1.889 NM_003741
CHRD
chordin
chr8_+_56015013 1.884 NM_052898
XKR4
XK, Kell blood group complex subunit-related family, member 4
chr9_+_126773851 1.875 NM_004789
LHX2
LIM homeobox 2
chr19_+_19322763 1.871 NM_004386
NCAN
neurocan
chr19_+_708766 1.867 NM_001040134
NM_002579
PALM

paralemmin

chr4_-_6474009 1.865 PPP2R2C
protein phosphatase 2, regulatory subunit B, gamma
chr16_+_84002099 1.859 NM_019065
NECAB2
N-terminal EF-hand calcium binding protein 2
chr20_-_39995497 1.853 NM_052846
EMILIN3
elastin microfibril interfacer 3
chr16_-_51185150 1.848 NM_002968
SALL1
sal-like 1 (Drosophila)
chr16_+_56225301 1.848 GNAO1
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
chr12_-_120806893 1.846 NM_002442
MSI1
musashi homolog 1 (Drosophila)
chr4_+_95679075 1.839 NM_001203
BMPR1B
bone morphogenetic protein receptor, type IB
chr14_+_105331581 1.839 NM_001112726
NM_015005
KIAA0284

KIAA0284

chr19_+_15218141 1.832 NM_033025
SYDE1
synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
chr16_+_56623266 1.817 NM_005954
MT3
metallothionein 3
chr21_+_18885296 1.809 CXADR
coxsackie virus and adenovirus receptor
chr4_-_46995440 1.806 NM_001204266
NM_001204267
GABRA4

gamma-aminobutyric acid (GABA) A receptor, alpha 4

chr17_+_42836546 1.801 NM_002390
ADAM11
ADAM metallopeptidase domain 11
chr13_-_101327102 1.794 NM_001079669
NM_032813
TMTC4

transmembrane and tetratricopeptide repeat containing 4

chr16_+_89894853 1.793 NM_032451
SPIRE2
spire homolog 2 (Drosophila)
chr11_+_35639734 1.791 NM_014344
FJX1
four jointed box 1 (Drosophila)
chr16_+_56225250 1.783 NM_020988
NM_138736
GNAO1

guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O

chr12_+_51985016 1.783 NM_014191
SCN8A
sodium channel, voltage gated, type VIII, alpha subunit
chr8_-_133493003 1.780 NM_004519
KCNQ3
potassium voltage-gated channel, KQT-like subfamily, member 3
chr7_+_86273867 1.778 GRM3
glutamate receptor, metabotropic 3
chr4_+_187065994 1.769 NM_015398
FAM149A
family with sequence similarity 149, member A
chr2_-_230579198 1.764 NM_139072
DNER
delta/notch-like EGF repeat containing
chr22_+_43808090 1.763 MPPED1
metallophosphoesterase domain containing 1
chr13_+_44947977 1.753 NM_001010897
SERP2
stress-associated endoplasmic reticulum protein family member 2
chr22_+_26565424 1.752 NM_001184773
NM_001184774
NM_001184775
NM_001184776
NM_001184777
NM_021115
SEZ6L





seizure related 6 homolog (mouse)-like





chr13_-_101327027 1.750 TMTC4
transmembrane and tetratricopeptide repeat containing 4
chr1_+_110693131 1.746 NM_001010898
SLC6A17
solute carrier family 6, member 17
chr16_+_56659584 1.739 NM_175617
MT1E
metallothionein 1E
chr14_+_96505566 1.737 NM_001252507
C14orf132
chromosome 14 open reading frame 132
chr9_+_80911990 1.737 NM_021154
NM_058179
PSAT1

phosphoserine aminotransferase 1

chr7_+_45614179 1.736 ADCY1
adenylate cyclase 1 (brain)
chr2_-_135476541 1.732 NM_030923
TMEM163
transmembrane protein 163
chr22_+_51039178 1.719 MAPK8IP2
mitogen-activated protein kinase 8 interacting protein 2
chr17_-_8534008 1.714 NM_005964
MYH10
myosin, heavy chain 10, non-muscle
chr20_-_36889173 1.703 NM_001029864
KIAA1755
KIAA1755
chr2_+_217498082 1.689 NM_000597
IGFBP2
insulin-like growth factor binding protein 2, 36kDa
chr7_-_98467663 1.679 NM_001134450
NM_001134451
NM_152913
TMEM130


transmembrane protein 130


chr1_+_99729847 1.677 NM_001166252
NM_014839
LPPR4

lipid phosphate phosphatase-related protein type 4

chr9_+_17578952 1.669 NM_003026
SH3GL2
SH3-domain GRB2-like 2
chr16_+_5083671 1.669 LOC100507589
uncharacterized LOC100507589
chr11_+_8102691 1.661 NM_177972
TUB
tubby homolog (mouse)
chr2_-_20424627 1.655 NM_002997
SDC1
syndecan 1
chr17_+_72983723 1.654 NM_014603
CDR2L
cerebellar degeneration-related protein 2-like
chr9_+_34958171 1.654 NM_015297
KIAA1045
KIAA1045
chr11_+_107462073 1.647 ELMOD1
ELMO/CED-12 domain containing 1
chr6_-_11044354 1.642 NM_017770
ELOVL2
ELOVL fatty acid elongase 2
chr20_+_6748744 1.626 NM_001200
BMP2
bone morphogenetic protein 2
chr2_+_73144603 1.625 NM_004097
EMX1
empty spiracles homeobox 1
chr13_-_29069215 1.621 NM_001159920
NM_001160030
NM_001160031
NM_002019
FLT1



fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)



chr19_+_1446268 1.620 APC2
adenomatosis polyposis coli 2
chr17_+_9548853 1.619 NM_153210
USP43
ubiquitin specific peptidase 43
chr19_-_13030074 1.618 NM_001105578
SYCE2
synaptonemal complex central element protein 2
chr17_-_5404304 1.612 NM_001162371
LOC728392
uncharacterized LOC728392
chr5_-_83680590 1.606 NM_005711
EDIL3
EGF-like repeats and discoidin I-like domains 3
chr1_+_55446464 1.600 NM_182532
TMEM61
transmembrane protein 61
chr19_-_57352055 1.596 NM_001146326
NM_001146327
NM_015363
NM_001146184
NM_001146185
NM_001146187
NM_006210
ZIM2


PEG3



zinc finger, imprinted 2


paternally expressed 3



chr22_-_38851012 1.596 NM_152868
KCNJ4
potassium inwardly-rectifying channel, subfamily J, member 4
chr1_+_237205701 1.589 NM_001035
RYR2
ryanodine receptor 2 (cardiac)
chr2_+_153191591 1.582 NM_052905
FMNL2
formin-like 2
chr2_-_56150862 1.581 EFEMP1
EGF containing fibulin-like extracellular matrix protein 1
chrX_-_13956445 1.581


chr20_+_36531548 1.578 VSTM2L
V-set and transmembrane domain containing 2 like
chr1_+_4715104 1.566 NM_001042478
NM_018836
AJAP1

adherens junctions associated protein 1

chr19_-_2721337 1.556 NM_145173
DIRAS1
DIRAS family, GTP-binding RAS-like 1
chr22_+_38864015 1.556 NM_006855
NM_016657
KDELR3

KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3

chr4_+_145567147 1.544 NM_022475
HHIP
hedgehog interacting protein
chr2_+_219187858 1.541 NM_022572
PNKD
paroxysmal nonkinesigenic dyskinesia
chr13_-_36705432 1.531 DCLK1
doublecortin-like kinase 1
chr15_+_84322809 1.529 NM_207517
ADAMTSL3
ADAMTS-like 3
chr2_-_74669005 1.517 RTKN
rhotekin
chr3_-_160822625 1.516 NM_033169
NM_001038628
NM_003781
NM_033167
NM_033168
B3GALNT1




beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)




chr2_-_74669026 1.510 RTKN
rhotekin
chr1_-_11714738 1.507 NM_012168
FBXO2
F-box protein 2
chr1_-_85358851 1.502 NM_012152
LPAR3
lysophosphatidic acid receptor 3
chr15_+_59730272 1.499 NM_152450
FAM81A
family with sequence similarity 81, member A
chr11_+_20691116 1.498 NM_006157
NM_201551
NELL1

NEL-like 1 (chicken)

chr22_+_18957970 1.497 DGCR5
DiGeorge syndrome critical region gene 5 (non-protein coding)
chr11_-_790103 1.493 NM_016564
CEND1
cell cycle exit and neuronal differentiation 1
chr10_-_44880452 1.472 NM_000609
NM_001033886
NM_001178134
NM_199168
CXCL12



chemokine (C-X-C motif) ligand 12



chr9_+_126774028 1.471 LHX2
LIM homeobox 2
chr4_-_5890142 1.464 CRMP1
collapsin response mediator protein 1
chr3_-_56502364 1.463 NM_015576
ERC2
ELKS/RAB6-interacting/CAST family member 2
chr15_+_69591272 1.460 NM_017705
PAQR5
progestin and adipoQ receptor family member V
chr20_-_32274070 1.460 E2F1
E2F transcription factor 1
chr17_-_27332888 1.457 NM_001098635
NM_178860
SEZ6

seizure related 6 homolog (mouse)

chr14_+_70346113 1.455 NM_001034852
NM_022137
SMOC1

SPARC related modular calcium binding 1

chr17_-_3796270 1.448 CAMKK1
calcium/calmodulin-dependent protein kinase kinase 1, alpha
chrX_+_68725077 1.448 NM_015686
FAM155B
family with sequence similarity 155, member B
chr10_-_61122219 1.422 NM_001001971
NM_001166698
NM_198215
FAM13C


family with sequence similarity 13, member C


chr3_+_133465204 1.417 TF
transferrin
chr2_-_107502609 1.416 NM_001142351
ST6GAL2
ST6 beta-galactosamide alpha-2,6-sialyltranferase 2
chr2_-_74669055 1.406 NM_001015055
RTKN
rhotekin
chr7_+_121513158 1.397 NM_001206838
NM_001206839
NM_002851
PTPRZ1


protein tyrosine phosphatase, receptor-type, Z polypeptide 1


chr19_-_44143943 1.395 NM_145296
CADM4
cell adhesion molecule 4
chr12_-_48152180 1.395 NM_001098532
NM_006105
RAPGEF3

Rap guanine nucleotide exchange factor (GEF) 3


Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
2.93 1.95e-12 GO:0007399 nervous system development
1.87 1.19e-08 GO:0023052 signaling
4.13 2.63e-08 GO:0019226 transmission of nerve impulse
4.13 2.63e-08 GO:0035637 multicellular organismal signaling
4.34 3.71e-08 GO:0007268 synaptic transmission
2.02 4.53e-08 GO:0048731 system development
4.02 5.42e-08 GO:0007417 central nervous system development
1.87 1.09e-07 GO:0007275 multicellular organismal development
3.06 1.10e-07 GO:0022008 neurogenesis
2.22 1.89e-07 GO:0030154 cell differentiation
3.09 2.41e-07 GO:0048699 generation of neurons
2.16 6.17e-07 GO:0048869 cellular developmental process
1.88 8.56e-07 GO:0048856 anatomical structure development
1.60 1.11e-06 GO:0032501 multicellular organismal process
1.74 4.01e-06 GO:0032502 developmental process
3.05 5.02e-06 GO:0007267 cell-cell signaling
4.11 1.21e-05 GO:0007420 brain development
5.43 1.32e-04 GO:0030900 forebrain development
2.50 2.13e-04 GO:0007154 cell communication
2.85 2.85e-04 GO:0030182 neuron differentiation
2.53 5.10e-04 GO:0048468 cell development
2.99 7.69e-04 GO:0048666 neuron development
3.16 7.80e-04 GO:0000904 cell morphogenesis involved in differentiation
3.07 2.28e-03 GO:0031175 neuron projection development
1.61 4.26e-03 GO:0007165 signal transduction
3.14 4.35e-03 GO:0048667 cell morphogenesis involved in neuron differentiation
3.09 5.69e-03 GO:0048812 neuron projection morphogenesis
3.10 8.97e-03 GO:0007409 axonogenesis
2.63 1.23e-02 GO:0032989 cellular component morphogenesis
1.97 1.35e-02 GO:0009653 anatomical structure morphogenesis
2.66 1.53e-02 GO:0000902 cell morphogenesis
2.59 1.56e-02 GO:0030030 cell projection organization
1.88 2.47e-02 GO:0023051 regulation of signaling
2.75 3.25e-02 GO:0048858 cell projection morphogenesis
2.73 3.70e-02 GO:0032990 cell part morphogenesis
2.36 3.76e-02 GO:0007155 cell adhesion
2.36 3.76e-02 GO:0022610 biological adhesion
5.37 4.89e-02 GO:0051924 regulation of calcium ion transport

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
1.47 3.12e-09 GO:0016020 membrane
4.46 3.76e-09 GO:0045202 synapse
2.17 1.32e-08 GO:0044459 plasma membrane part
1.72 7.77e-08 GO:0005886 plasma membrane
1.71 8.57e-08 GO:0071944 cell periphery
1.48 1.78e-06 GO:0044425 membrane part
4.35 3.98e-06 GO:0044456 synapse part
3.74 7.08e-06 GO:0043005 neuron projection
3.06 2.19e-05 GO:0030054 cell junction
4.76 1.43e-04 GO:0030425 dendrite
9.55 3.47e-04 GO:0044309 neuron spine
2.12 9.54e-04 GO:0005887 integral to plasma membrane
2.08 1.51e-03 GO:0031226 intrinsic to plasma membrane
8.71 2.97e-03 GO:0043197 dendritic spine
6.18 3.18e-03 GO:0008021 synaptic vesicle
1.40 3.53e-03 GO:0016021 integral to membrane
5.43 9.00e-03 GO:0019717 synaptosome
1.38 9.12e-03 GO:0031224 intrinsic to membrane
2.12 2.59e-02 GO:0042995 cell projection

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
4.47 9.13e-04 GO:0005244 voltage-gated ion channel activity
4.47 9.13e-04 GO:0022832 voltage-gated channel activity
3.57 9.51e-04 GO:0022836 gated channel activity
5.05 1.33e-03 GO:0022843 voltage-gated cation channel activity
2.96 1.71e-03 GO:0030695 GTPase regulator activity
2.88 2.61e-03 GO:0060589 nucleoside-triphosphatase regulator activity
3.62 2.81e-03 GO:0005261 cation channel activity
2.98 6.77e-03 GO:0005216 ion channel activity
2.93 8.39e-03 GO:0022838 substrate-specific channel activity
2.14 1.16e-02 GO:0030234 enzyme regulator activity
35.81 1.21e-02 GO:0046870 cadmium ion binding
2.85 1.27e-02 GO:0015267 channel activity
2.84 1.31e-02 GO:0022803 passive transmembrane transporter activity
11.94 1.38e-02 GO:0030295 protein kinase activator activity
2.84 2.07e-02 GO:0008047 enzyme activator activity
9.95 3.45e-02 GO:0019209 kinase activator activity
5.25 3.87e-02 GO:0019887 protein kinase regulator activity
9.63 4.05e-02 GO:0005272 sodium channel activity