Motif ID: MYFfamily.p2

Z-value: 3.626


Transcription factors associated with MYFfamily.p2:

Gene SymbolEntrez IDGene Name
MYF5 4617 myogenic factor 5
MYF6 4618 myogenic factor 6 (herculin)
MYOD1 4654 myogenic differentiation 1
MYOG 4656 myogenin (myogenic factor 4)

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
MYOD1hg19_v1_chr11_+_17741109_17741329-0.531.7e-03Click!
MYF6hg19_v1_chr12_+_81101407_81101498-0.522.1e-03Click!
MYF5hg19_v1_chr12_+_81110689_81110842-0.494.4e-03Click!
MYOGhg19_v1_chr1_-_203055376_203055376-0.468.9e-03Click!


Activity profile for motif MYFfamily.p2.

activity profile for motif MYFfamily.p2


Sorted Z-values histogram for motif MYFfamily.p2

Sorted Z-values for motif MYFfamily.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of MYFfamily.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr11_-_130298502 9.433 NM_007037
 ADAMTS8
ADAM metallopeptidase with thrombospondin type 1 motif, 8
chr11_-_130298305 8.752 ADAMTS8
ADAM metallopeptidase with thrombospondin type 1 motif, 8
chr3_+_159943628 8.251 C3orf80
chromosome 3 open reading frame 80
chr3_+_111717585 6.666 NM_001008272
NM_013259
 TAGLN3

transgelin 3

chr2_+_187558654 6.475 NM_177454
 FAM171B
family with sequence similarity 171, member B
chr3_+_159943252 6.146 NM_001168214
 C3orf80
chromosome 3 open reading frame 80
chr8_+_65493610 6.039 BHLHE22
basic helix-loop-helix family, member e22
chr4_-_5021095 6.024 NM_018659
 CYTL1
cytokine-like 1
chr8_-_23712297 5.461 NM_003155
 STC1
stanniocalcin 1
chr22_+_22712091 5.438 IGLV1-44
IGL@
immunoglobulin lambda variable 1-44
immunoglobulin lambda locus
chr3_+_111718006 5.437 NM_001008273
 TAGLN3
transgelin 3
chr11_-_9113092 5.414 NM_001170690
NM_020974
 SCUBE2

signal peptide, CUB domain, EGF-like 2

chr16_+_29823557 5.371 PRRT2
proline-rich transmembrane protein 2
chr16_+_86544233 5.366 FOXF1
forkhead box F1
chr5_+_92920592 5.307 NR2F1
NR2F2
nuclear receptor subfamily 2, group F, member 1
nuclear receptor subfamily 2, group F, member 2
chr2_+_79740059 5.256 NM_001164883
NM_004389
 CTNNA2

catenin (cadherin-associated protein), alpha 2

chr2_-_230579198 4.947 NM_139072
 DNER
delta/notch-like EGF repeat containing
chr6_+_99282597 4.794 POU3F2
POU class 3 homeobox 2
chr5_+_137801178 4.725 NM_001964
 EGR1
early growth response 1
chr1_-_59042827 4.651 TACSTD2
tumor-associated calcium signal transducer 2

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 53 entries
Enrichment   P-value GO Accession GO Term
44.56 3.68e-04 GO:0045110 intermediate filament bundle assembly
19.81 4.24e-02 GO:0045109 intermediate filament organization
8.91 1.58e-02 GO:0003014 renal system process
4.64 1.32e-03 GO:0043062 extracellular structure organization
3.40 5.69e-03 GO:0001568 blood vessel development
3.36 2.20e-03 GO:0016337 cell-cell adhesion
3.33 4.45e-03 GO:0001944 vasculature development
3.20 2.80e-03 GO:0007411 axon guidance
3.13 3.60e-09 GO:0007155 cell adhesion
3.13 3.60e-09 GO:0022610 biological adhesion
3.05 6.15e-05 GO:0000904 cell morphogenesis involved in differentiation
3.05 4.45e-02 GO:0007423 sensory organ development
3.01 1.01e-03 GO:0007409 axonogenesis
2.97 3.87e-02 GO:0022603 regulation of anatomical structure morphogenesis
2.91 1.97e-03 GO:0048667 cell morphogenesis involved in neuron differentiation
2.86 2.72e-03 GO:0048812 neuron projection morphogenesis
2.82 8.63e-03 GO:0016477 cell migration
2.65 9.28e-04 GO:0000902 cell morphogenesis
2.63 1.43e-04 GO:0030182 neuron differentiation
2.62 2.33e-04 GO:0045595 regulation of cell differentiation

Gene overrepresentation in compartment category:

Showing 1 to 20 of 22 entries
Enrichment   P-value GO Accession GO Term
7.43 2.81e-02 GO:0005581 collagen
5.73 5.36e-03 GO:0005604 basement membrane
4.73 1.87e-03 GO:0044420 extracellular matrix part
4.37 2.86e-09 GO:0005578 proteinaceous extracellular matrix
4.20 3.66e-10 GO:0031012 extracellular matrix
3.86 2.88e-02 GO:0031225 anchored to membrane
2.93 6.07e-04 GO:0009986 cell surface
2.58 1.42e-08 GO:0044421 extracellular region part
2.23 1.13e-06 GO:0031226 intrinsic to plasma membrane
2.20 1.97e-11 GO:0005576 extracellular region
2.20 3.73e-06 GO:0005887 integral to plasma membrane
2.19 2.38e-05 GO:0000267 cell fraction
2.10 5.16e-03 GO:0005624 membrane fraction
2.10 6.95e-03 GO:0005615 extracellular space
2.09 4.39e-03 GO:0005626 insoluble fraction
1.73 1.62e-04 GO:0044459 plasma membrane part
1.58 9.91e-07 GO:0005886 plasma membrane
1.57 1.35e-06 GO:0071944 cell periphery
1.49 3.44e-07 GO:0031224 intrinsic to membrane
1.46 3.26e-06 GO:0016021 integral to membrane

Gene overrepresentation in function category:

Showing 1 to 10 of 10 entries
Enrichment   P-value GO Accession GO Term
26.74 3.46e-02 GO:0031694 alpha-2A adrenergic receptor binding
16.21 2.33e-02 GO:0048407 platelet-derived growth factor binding
9.69 4.30e-02 GO:0005520 insulin-like growth factor binding
8.91 7.98e-04 GO:0003823 antigen binding
6.37 3.48e-03 GO:0004714 transmembrane receptor protein tyrosine kinase activity
5.50 4.28e-03 GO:0019199 transmembrane receptor protein kinase activity
5.00 1.64e-03 GO:0019838 growth factor binding
2.20 1.23e-02 GO:0005509 calcium ion binding
1.96 8.07e-03 GO:0005102 receptor binding
1.64 4.17e-02 GO:0004872 receptor activity