Motif ID: MZF1.p2

Z-value: 3.343


Transcription factors associated with MZF1.p2:

Gene SymbolEntrez IDGene Name
MZF1 7593 myeloid zinc finger 1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
MZF1hg19_v1_chr19_-_59084630_590846940.612.0e-04Click!


Activity profile for motif MZF1.p2.

activity profile for motif MZF1.p2


Sorted Z-values histogram for motif MZF1.p2

Sorted Z-values for motif MZF1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of MZF1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr12_+_58005217 11.639 NM_182947
 ARHGEF25
Rho guanine nucleotide exchange factor (GEF) 25
chr20_-_62103815 11.556 NM_004518
NM_172106
NM_172107
NM_172108
NM_172109
 KCNQ2




potassium voltage-gated channel, KQT-like subfamily, member 2




chr16_-_30042123 11.455 NM_031478
 FAM57B
family with sequence similarity 57, member B
chr19_-_47975244 9.634 NM_015063
 SLC8A2
solute carrier family 8 (sodium/calcium exchanger), member 2
chr19_-_291335 9.596 NM_003712
NM_177526
 PPAP2C

phosphatidic acid phosphatase type 2C

chr19_+_55795766 9.312 BRSK1
BR serine/threonine kinase 1
chr19_-_36523540 9.217 NM_001199570
 CLIP3
CAP-GLY domain containing linker protein 3
chr2_+_69240137 8.843 NM_018153
NM_032208
NM_053034
 ANTXR1


anthrax toxin receptor 1


chr13_-_108519459 8.570 NM_001080396
 FAM155A
family with sequence similarity 155, member A
chr6_+_17393610 8.311 NM_006366
 CAP2
CAP, adenylate cyclase-associated protein, 2 (yeast)
chr19_-_47975074 8.049 SLC8A2
solute carrier family 8 (sodium/calcium exchanger), member 2
chrX_+_100474932 7.880 NM_001171184
NM_001939
 DRP2

dystrophin related protein 2

chr10_-_119301750 7.666 EMX2OS
EMX2 opposite strand/antisense RNA (non-protein coding)
chr19_-_51487070 7.600 NM_139277
NM_001207053
NM_001243126
NM_005046
 KLK7



kallikrein-related peptidase 7



chr10_+_73723992 7.482 NM_004273
 CHST3
carbohydrate (chondroitin 6) sulfotransferase 3
chr14_-_23834378 7.373 EFS
embryonal Fyn-associated substrate
chr7_+_128432049 7.355 NM_022742
 CCDC136
coiled-coil domain containing 136
chr6_-_125623214 7.312 NM_016063
 HDDC2
HD domain containing 2
chr17_+_42385780 7.290 NM_001144825
NM_001144826
NM_006695
 RUNDC3A


RUN domain containing 3A


chr1_-_72748147 7.199 NM_173808
 NEGR1
neuronal growth regulator 1

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 110 entries
Enrichment   P-value GO Accession GO Term
13.06 2.47e-02 GO:0005513 detection of calcium ion
6.97 5.52e-03 GO:0030199 collagen fibril organization
5.88 2.66e-02 GO:0048489 synaptic vesicle transport
5.75 3.73e-03 GO:0001656 metanephros development
5.36 2.18e-02 GO:0021987 cerebral cortex development
5.10 3.53e-02 GO:0014020 primary neural tube formation
4.92 7.74e-03 GO:0032412 regulation of ion transmembrane transporter activity
4.73 1.19e-02 GO:0022898 regulation of transmembrane transporter activity
4.72 2.09e-03 GO:0032409 regulation of transporter activity
4.60 3.88e-02 GO:0001764 neuron migration
4.56 1.79e-02 GO:0007612 learning
4.48 2.18e-02 GO:0021543 pallium development
4.48 2.18e-02 GO:0034765 regulation of ion transmembrane transport
4.05 7.41e-04 GO:0006816 calcium ion transport
3.95 2.23e-03 GO:0021537 telencephalon development
3.76 2.27e-03 GO:0051924 regulation of calcium ion transport
3.73 6.69e-04 GO:0050804 regulation of synaptic transmission
3.71 1.43e-03 GO:0007611 learning or memory
3.69 3.07e-03 GO:0006836 neurotransmitter transport
3.60 1.63e-02 GO:0030324 lung development

Gene overrepresentation in compartment category:

Showing 1 to 20 of 50 entries
Enrichment   P-value GO Accession GO Term
16.72 8.15e-03 GO:0014701 junctional sarcoplasmic reticulum membrane
10.45 1.67e-02 GO:0030934 anchoring collagen
7.96 1.02e-03 GO:0005891 voltage-gated calcium channel complex
7.21 1.73e-04 GO:0034704 calcium channel complex
5.81 1.62e-03 GO:0005581 collagen
4.80 6.73e-11 GO:0034703 cation channel complex
4.65 1.37e-02 GO:0030672 synaptic vesicle membrane
4.40 1.61e-04 GO:0033267 axon part
4.33 4.18e-05 GO:0008076 voltage-gated potassium channel complex
4.33 4.18e-05 GO:0034705 potassium channel complex
4.25 2.86e-03 GO:0030426 growth cone
4.22 4.71e-13 GO:0034702 ion channel complex
4.18 3.55e-02 GO:0044309 neuron spine
4.12 4.08e-03 GO:0030427 site of polarized growth
4.01 6.60e-05 GO:0019717 synaptosome
3.83 2.24e-20 GO:0045202 synapse
3.70 6.79e-03 GO:0014069 postsynaptic density
3.68 9.64e-08 GO:0030424 axon
3.44 1.59e-02 GO:0030665 clathrin coated vesicle membrane
3.41 4.56e-11 GO:0044456 synapse part

Gene overrepresentation in function category:

Showing 1 to 20 of 35 entries
Enrichment   P-value GO Accession GO Term
9.50 4.21e-02 GO:0017075 syntaxin-1 binding
8.21 1.37e-05 GO:0008066 glutamate receptor activity
8.13 5.29e-03 GO:0005234 extracellular-glutamate-gated ion channel activity
7.38 4.35e-02 GO:0004970 ionotropic glutamate receptor activity
7.24 8.96e-04 GO:0005245 voltage-gated calcium channel activity
6.65 2.39e-02 GO:0016917 GABA receptor activity
4.70 1.52e-05 GO:0005201 extracellular matrix structural constituent
4.12 6.68e-08 GO:0022843 voltage-gated cation channel activity
3.98 1.78e-02 GO:0004714 transmembrane receptor protein tyrosine kinase activity
3.82 1.36e-05 GO:0005267 potassium channel activity
3.80 7.19e-03 GO:0005262 calcium channel activity
3.77 1.55e-02 GO:0005230 extracellular ligand-gated ion channel activity
3.68 6.27e-14 GO:0022836 gated channel activity
3.58 1.54e-07 GO:0005244 voltage-gated ion channel activity
3.58 1.54e-07 GO:0022832 voltage-gated channel activity
3.41 7.79e-10 GO:0005261 cation channel activity
3.41 7.54e-03 GO:0005249 voltage-gated potassium channel activity
3.19 1.11e-12 GO:0022838 substrate-specific channel activity
3.18 2.07e-12 GO:0005216 ion channel activity
3.18 3.67e-03 GO:0015276 ligand-gated ion channel activity