Motif ID: MZF1.p2

Z-value: 3.343


Transcription factors associated with MZF1.p2:

Gene SymbolEntrez IDGene Name
MZF1 7593 myeloid zinc finger 1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
MZF1hg19_v1_chr19_-_59084630_590846940.612.0e-04Click!


Activity profile for motif MZF1.p2.

activity profile for motif MZF1.p2


Sorted Z-values histogram for motif MZF1.p2

Sorted Z-values for motif MZF1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of MZF1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr12_+_58005217 11.639 NM_182947
ARHGEF25
Rho guanine nucleotide exchange factor (GEF) 25
chr20_-_62103815 11.556 NM_004518
NM_172106
NM_172107
NM_172108
NM_172109
KCNQ2




potassium voltage-gated channel, KQT-like subfamily, member 2




chr16_-_30042123 11.455 NM_031478
FAM57B
family with sequence similarity 57, member B
chr19_-_47975244 9.634 NM_015063
SLC8A2
solute carrier family 8 (sodium/calcium exchanger), member 2
chr19_-_291335 9.596 NM_003712
NM_177526
PPAP2C

phosphatidic acid phosphatase type 2C

chr19_+_55795766 9.312 BRSK1
BR serine/threonine kinase 1
chr19_-_36523540 9.217 NM_001199570
CLIP3
CAP-GLY domain containing linker protein 3
chr2_+_69240137 8.843 NM_018153
NM_032208
NM_053034
ANTXR1


anthrax toxin receptor 1


chr13_-_108519459 8.570 NM_001080396
FAM155A
family with sequence similarity 155, member A
chr6_+_17393610 8.311 NM_006366
CAP2
CAP, adenylate cyclase-associated protein, 2 (yeast)
chr19_-_47975074 8.049 SLC8A2
solute carrier family 8 (sodium/calcium exchanger), member 2
chrX_+_100474932 7.880 NM_001171184
NM_001939
DRP2

dystrophin related protein 2

chr10_-_119301750 7.666 EMX2OS
EMX2 opposite strand/antisense RNA (non-protein coding)
chr19_-_51487070 7.600 NM_139277
NM_001207053
NM_001243126
NM_005046
KLK7



kallikrein-related peptidase 7



chr10_+_73723992 7.482 NM_004273
CHST3
carbohydrate (chondroitin 6) sulfotransferase 3
chr14_-_23834378 7.373 EFS
embryonal Fyn-associated substrate
chr7_+_128432049 7.355 NM_022742
CCDC136
coiled-coil domain containing 136
chr6_-_125623214 7.312 NM_016063
HDDC2
HD domain containing 2
chr17_+_42385780 7.290 NM_001144825
NM_001144826
NM_006695
RUNDC3A


RUN domain containing 3A


chr1_-_72748147 7.199 NM_173808
NEGR1
neuronal growth regulator 1
chr14_-_23834234 7.081


chr13_-_36705432 6.895 DCLK1
doublecortin-like kinase 1
chr21_+_47401644 6.749 NM_001848
COL6A1
collagen, type VI, alpha 1
chr15_-_88799961 6.685 NM_001007156
NM_001012338
NM_001243101
NM_002530
NTRK3



neurotrophic tyrosine kinase, receptor, type 3



chr1_-_72748491 6.584


chrX_+_103031797 6.573 PLP1
proteolipid protein 1
chr17_+_7311501 6.552 NM_020795
NLGN2
neuroligin 2
chr10_+_119301955 6.548 NM_001165924
NM_004098
EMX2

empty spiracles homeobox 2

chr14_-_23834417 6.388 EFS
embryonal Fyn-associated substrate
chr14_-_23834399 6.387 EFS
embryonal Fyn-associated substrate
chr3_-_116164363 6.328 NM_002338
LSAMP
limbic system-associated membrane protein
chr8_-_144241725 6.244 NM_001135655
LY6H
lymphocyte antigen 6 complex, locus H
chr4_-_154710207 6.224 NM_003013
SFRP2
secreted frizzled-related protein 2
chr4_-_105416050 6.182 CXXC4
CXXC finger protein 4
chr5_+_175298492 6.178 NM_001008220
CPLX2
complexin 2
chr1_+_220701800 6.140 MARK1
MAP/microtubule affinity-regulating kinase 1
chr12_+_57943843 6.091 NM_004984
KIF5A
kinesin family member 5A
chr4_+_30721865 6.087 NM_032456
NM_001173523
NM_002589
NM_032457
PCDH7



protocadherin 7



chr1_+_164528586 6.073 NM_001204961
NM_001204963
NM_002585
PBX1


pre-B-cell leukemia homeobox 1


chr14_-_23822025 5.970 NM_016609
SLC22A17
solute carrier family 22, member 17
chr6_-_6007097 5.908 NRN1
neuritin 1
chr9_+_8858130 5.896


chr15_-_79383080 5.850 NM_001145648
NM_002891
RASGRF1

Ras protein-specific guanine nucleotide-releasing factor 1

chr7_+_100081549 5.841 NM_173564
NYAP1
neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 1
chr6_-_29600668 5.801 GABBR1
gamma-aminobutyric acid (GABA) B receptor, 1
chr8_-_22089517 5.764 PHYHIP
phytanoyl-CoA 2-hydroxylase interacting protein
chr19_-_49149252 5.758 NM_001217
CA11
carbonic anhydrase XI
chr2_+_115919512 5.680 NM_001178034
NM_001004360
DPP10

dipeptidyl-peptidase 10 (non-functional)

chr5_-_172755195 5.678 STC2
stanniocalcin 2
chr4_-_46391771 5.668 NM_000807
GABRA2
gamma-aminobutyric acid (GABA) A receptor, alpha 2
chr6_-_32119717 5.665 NM_030651
PRRT1
proline-rich transmembrane protein 1
chr19_-_36523770 5.649 NM_015526
CLIP3
CAP-GLY domain containing linker protein 3
chr9_+_133971902 5.631 AIF1L
allograft inflammatory factor 1-like
chr12_-_50297575 5.617 NM_012306
FAIM2
Fas apoptotic inhibitory molecule 2
chr19_-_51071279 5.614 NM_001080457
LRRC4B
leucine rich repeat containing 4B
chr2_+_172950207 5.600 NM_001038493
NM_178120
DLX1

distal-less homeobox 1

chr19_+_708766 5.592 NM_001040134
NM_002579
PALM

paralemmin

chr2_+_220325533 5.587 NM_001173476
SPEG
SPEG complex locus
chr2_-_152955502 5.527 NM_000726
NM_001145798
CACNB4

calcium channel, voltage-dependent, beta 4 subunit

chr4_-_168155732 5.505 NM_001040159
NM_001204352
NM_001204354
NM_001204355
NM_001204356
NM_001204358
NM_001251967
NM_016950
SPOCK3







sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3







chr22_-_38380538 5.482 NM_006941
SOX10
SRY (sex determining region Y)-box 10
chr9_+_130374466 5.472 NM_001032221
NM_003165
STXBP1

syntaxin binding protein 1

chr2_-_56150862 5.439 EFEMP1
EGF containing fibulin-like extracellular matrix protein 1
chr22_+_35936891 5.439


chr1_+_160370363 5.399 NM_020335
VANGL2
vang-like 2 (van gogh, Drosophila)
chr15_-_37392322 5.391 MEIS2
Meis homeobox 2
chr5_+_92920592 5.379 NR2F1
NR2F2
nuclear receptor subfamily 2, group F, member 1
nuclear receptor subfamily 2, group F, member 2
chr20_-_55841090 5.368 BMP7
bone morphogenetic protein 7
chr17_+_70117154 5.354 NM_000346
SOX9
SRY (sex determining region Y)-box 9
chr19_-_291168 5.302 NM_177543
PPAP2C
phosphatidic acid phosphatase type 2C
chr1_-_177133818 5.279 ASTN1
astrotactin 1
chr9_+_2622052 5.268 VLDLR
very low density lipoprotein receptor
chr8_+_104512975 5.260 NM_001100117
RIMS2
regulating synaptic membrane exocytosis 2
chr1_-_1475739 5.206 NM_001114748
TMEM240
transmembrane protein 240
chr14_-_24047993 5.156 NM_001146028
NM_032452
JPH4

junctophilin 4

chr20_+_53092131 5.150 NM_018431
DOK5
docking protein 5
chrX_+_103031753 5.144 NM_000533
NM_199478
PLP1

proteolipid protein 1

chr14_-_27066959 5.141 NM_002515
NM_006489
NM_006491
NOVA1


neuro-oncological ventral antigen 1


chr3_+_181429711 5.127 NM_003106
SOX2
SRY (sex determining region Y)-box 2
chr19_+_41036367 5.127 NM_025213
SPTBN4
spectrin, beta, non-erythrocytic 4
chr15_-_83876165 5.125 NM_016073
HDGFRP3
hepatoma-derived growth factor, related protein 3
chr2_+_48757292 5.086 NM_001198595
NM_006873
STON1

stonin 1

chr19_-_35625989 5.085 NM_139284
LGI4
leucine-rich repeat LGI family, member 4
chr19_-_2721337 5.023 NM_145173
DIRAS1
DIRAS family, GTP-binding RAS-like 1
chr8_-_144241918 5.022 NM_001130478
LY6H
lymphocyte antigen 6 complex, locus H
chr6_+_121756744 5.019 NM_000165
GJA1
gap junction protein, alpha 1, 43kDa
chr11_-_64410785 5.011 NM_138734
NRXN2
neurexin 2
chr2_+_39893021 5.000 NM_152390
TMEM178
transmembrane protein 178
chr19_+_55795533 4.991 NM_032430
BRSK1
BR serine/threonine kinase 1
chr17_+_64960754 4.966 NM_014405
CACNG4
calcium channel, voltage-dependent, gamma subunit 4
chr16_+_29912146 4.954 NM_181718
ASPHD1
aspartate beta-hydroxylase domain containing 1
chrX_+_144899330 4.940 NM_001144003
NM_001144004
NM_001144005
NM_032539
SLITRK2



SLIT and NTRK-like family, member 2



chr11_+_125034604 4.926 PKNOX2
PBX/knotted 1 homeobox 2
chr17_+_37783202 4.925 PPP1R1B
protein phosphatase 1, regulatory (inhibitor) subunit 1B
chr6_-_32119667 4.918 PRRT1
proline-rich transmembrane protein 1
chr2_+_17721806 4.903 NM_003385
VSNL1
visinin-like 1
chrX_+_119029799 4.892 NM_001008534
NM_001008535
NM_178813
AKAP14


A kinase (PRKA) anchor protein 14


chr5_-_92916924 4.881 FLJ42709
uncharacterized LOC441094
chr15_-_37392358 4.877 NM_170674
NM_170675
NM_170676
NM_170677
MEIS2



Meis homeobox 2



chr11_+_17757494 4.864 NM_001112741
NM_004976
KCNC1

potassium voltage-gated channel, Shaw-related subfamily, member 1

chr20_+_5891973 4.838 NM_001819
CHGB
chromogranin B (secretogranin 1)
chr15_-_37391893 4.774 MEIS2
Meis homeobox 2
chr11_-_62688732 4.772 CHRM1
cholinergic receptor, muscarinic 1
chr9_+_2622134 4.707 VLDLR
very low density lipoprotein receptor
chr6_+_21666645 4.674 LINC00340
long intergenic non-protein coding RNA 340
chr2_+_210636700 4.667 NM_032504
NM_182587
UNC80

unc-80 homolog (C. elegans)

chr6_+_127440047 4.666 NM_032784
RSPO3
R-spondin 3
chr12_+_49209300 4.665 NM_001206916
CACNB3
calcium channel, voltage-dependent, beta 3 subunit
chr14_+_29236171 4.660 NM_005249
FOXG1
forkhead box G1
chr9_+_2622099 4.643 VLDLR
very low density lipoprotein receptor
chr8_+_95653340 4.617 NM_001034915
NM_001122825
NM_001122826
NM_001122827
NM_017697
ESRP1




epithelial splicing regulatory protein 1




chr5_-_73936299 4.612 ENC1
ectodermal-neural cortex 1 (with BTB-like domain)
chr2_-_51259536 4.605 NM_001135659
NM_004801
NRXN1

neurexin 1

chr3_-_116164321 4.593 LSAMP
limbic system-associated membrane protein
chr9_+_109625347 4.588 NM_021224
ZNF462
zinc finger protein 462
chr16_-_65155881 4.549 NM_001797
CDH11
cadherin 11, type 2, OB-cadherin (osteoblast)
chr9_-_124990949 4.533 NM_014368
NM_199160
LHX6

LIM homeobox 6

chr2_-_237416091 4.491 NM_024726
IQCA1
IQ motif containing with AAA domain 1
chr6_-_29600959 4.474 NM_001470
NM_021904
GABBR1

gamma-aminobutyric acid (GABA) B receptor, 1

chr5_+_148786439 4.470 MIR143HG
MIR143 host gene (non-protein coding)
chr12_-_118406027 4.464 NM_173598
KSR2
kinase suppressor of ras 2
chr17_+_70117168 4.417 SOX9
SRY (sex determining region Y)-box 9
chrX_-_119445306 4.409 NM_001104544
NM_001104545
NM_017938
FAM70A


family with sequence similarity 70, member A


chr2_+_48757063 4.390 NM_001198593
STON1-GTF2A1L
STON1-GTF2A1L readthrough
chr11_-_62689011 4.382 NM_000738
CHRM1
cholinergic receptor, muscarinic 1
chr17_+_40913233 4.346 RAMP2
receptor (G protein-coupled) activity modifying protein 2
chr13_-_44361032 4.334 NM_001242863
NM_017993
ENOX1

ecto-NOX disulfide-thiol exchanger 1

chr6_-_112575766 4.334 NM_001105206
NM_001105207
NM_001105208
NM_001105209
NM_002290
LAMA4




laminin, alpha 4




chr7_+_31092067 4.317 NM_001118
NM_001199635
NM_001199636
NM_001199637
ADCYAP1R1



adenylate cyclase activating polypeptide 1 (pituitary) receptor type I



chr19_-_11591439 4.248 NM_001420
NM_032281
ELAVL3

ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C)

chr11_-_64490654 4.234 NM_015080
NM_138732
NRXN2

neurexin 2

chr5_+_92918924 4.205 NM_005654
NR2F1
nuclear receptor subfamily 2, group F, member 1
chr6_-_29600859 4.201 GABBR1
gamma-aminobutyric acid (GABA) B receptor, 1
chr17_+_39969205 4.194 FKBP10
FK506 binding protein 10, 65 kDa
chr14_-_23834841 4.159 NM_005864
NM_032459
EFS

embryonal Fyn-associated substrate

chr8_+_27491460 4.156 NM_016240
NM_182826
SCARA3

scavenger receptor class A, member 3

chr15_+_80696569 4.151 NM_014862
ARNT2
aryl-hydrocarbon receptor nuclear translocator 2
chr7_-_108096693 4.139 NM_001193582
NM_001193583
NM_001193584
NM_005010
NRCAM



neuronal cell adhesion molecule



chr12_+_53491448 4.118 IGFBP6
insulin-like growth factor binding protein 6
chr14_-_53417808 4.099 NM_001134999
NM_001135000
NM_006832
FERMT2


fermitin family member 2


chr14_-_24020766 4.071 NM_033400
ZFHX2
zinc finger homeobox 2
chr16_+_86544104 4.019 NM_001451
FOXF1
forkhead box F1
chr1_-_57045129 4.014 PPAP2B
phosphatidic acid phosphatase type 2B
chr2_-_56151273 4.007 NM_001039348
NM_001039349
EFEMP1

EGF containing fibulin-like extracellular matrix protein 1

chr16_-_65155984 4.003 CDH11
cadherin 11, type 2, OB-cadherin (osteoblast)
chr3_-_150421718 4.002 NM_152394
FAM194A
family with sequence similarity 194, member A
chr10_+_119302709 3.981


chrX_-_128788913 3.976 NM_017413
APLN
apelin
chr20_-_18038520 3.971 NM_021220
OVOL2
ovo-like 2 (Drosophila)
chr14_+_96342728 3.967 LOC100507043
uncharacterized LOC100507043
chr11_-_47615902 3.959 NM_031909
C1QTNF4
C1q and tumor necrosis factor related protein 4
chr20_-_55841671 3.936 NM_001719
BMP7
bone morphogenetic protein 7
chr2_+_39892637 3.935 NM_001167959
TMEM178
transmembrane protein 178
chr1_+_205473768 3.935 CDK18
cyclin-dependent kinase 18
chr2_+_17721983 3.890 VSNL1
visinin-like 1
chr8_+_24771276 3.872 NEFM
neurofilament, medium polypeptide
chr2_+_105471745 3.861 NM_006236
POU3F3
POU class 3 homeobox 3
chr1_+_20878931 3.857 NM_207334
FAM43B
family with sequence similarity 43, member B
chrX_+_122318095 3.840 NM_000828
NM_007325
GRIA3

glutamate receptor, ionotrophic, AMPA 3

chr2_+_187558654 3.838 NM_177454
FAM171B
family with sequence similarity 171, member B
chr13_+_88324777 3.817 NM_015567
SLITRK5
SLIT and NTRK-like family, member 5
chr13_-_36705513 3.813 NM_004734
DCLK1
doublecortin-like kinase 1
chr3_+_96533424 3.813 NM_001080448
EPHA6
EPH receptor A6
chr17_+_70117177 3.810 SOX9
SRY (sex determining region Y)-box 9
chr11_-_119187811 3.804 NM_006500
MCAM
melanoma cell adhesion molecule
chr6_+_41606193 3.781 NM_005586
MDFI
MyoD family inhibitor
chr12_+_57943806 3.778 KIF5A
kinesin family member 5A
chr7_-_79082870 3.742 NM_012301
MAGI2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr6_-_94129059 3.731 NM_004440
EPHA7
EPH receptor A7
chr8_-_144241678 3.719 LY6H
lymphocyte antigen 6 complex, locus H
chr8_+_95653272 3.715 ESRP1
epithelial splicing regulatory protein 1
chrX_-_102531673 3.709 NM_001012979
TCEAL5
transcription elongation factor A (SII)-like 5
chr6_+_1390068 3.691 NM_001452
FOXF2
forkhead box F2
chr7_+_103969103 3.683 NM_199000
LHFPL3
lipoma HMGIC fusion partner-like 3
chr12_+_53491417 3.675 NM_002178
IGFBP6
insulin-like growth factor binding protein 6
chr9_-_122131579 3.668 NM_014618
DBC1
deleted in bladder cancer 1
chr22_+_48972117 3.667 NM_015381
FAM19A5
family with sequence similarity 19 (chemokine (C-C motif)-like), member A5
chr11_+_125034558 3.662 NM_022062
PKNOX2
PBX/knotted 1 homeobox 2
chr6_-_6007632 3.657 NM_016588
NRN1
neuritin 1
chr12_+_6937570 3.637 NM_014262
LEPREL2
leprecan-like 2
chr18_-_35145603 3.621 CELF4
CUGBP, Elav-like family member 4
chr19_-_51472003 3.615 NM_001012964
NM_001012965
KLK6

kallikrein-related peptidase 6

chr12_-_48152180 3.615 NM_001098532
NM_006105
RAPGEF3

Rap guanine nucleotide exchange factor (GEF) 3

chr1_+_205473683 3.608 NM_002596
NM_212502
NM_212503
CDK18


cyclin-dependent kinase 18


chr8_+_24771268 3.608 NM_005382
NEFM
neurofilament, medium polypeptide
chr14_-_54423448 3.586 NM_001202
NM_130850
BMP4

bone morphogenetic protein 4

chr8_+_95653399 3.572 ESRP1
epithelial splicing regulatory protein 1
chr20_-_48184652 3.565 NM_000961
PTGIS
prostaglandin I2 (prostacyclin) synthase
chr2_+_79740059 3.538 NM_001164883
NM_004389
CTNNA2

catenin (cadherin-associated protein), alpha 2

chr9_+_139249251 3.526 NM_001200003
GPSM1
G-protein signaling modulator 1
chr11_-_62457001 3.508 LRRN4CL
LRRN4 C-terminal like
chr19_-_54984341 3.499 NM_145057
CDC42EP5
CDC42 effector protein (Rho GTPase binding) 5
chr5_+_175298538 3.483 CPLX2
complexin 2
chr1_+_47489239 3.483 NM_178033
CYP4X1
cytochrome P450, family 4, subfamily X, polypeptide 1
chr14_-_53417636 3.482 FERMT2
fermitin family member 2
chr12_+_2162388 3.475 NM_000719
NM_001129827
NM_001129829
NM_001129830
NM_001129831
NM_001129832
NM_001129833
NM_001129834
NM_001129835
NM_001129836
NM_001129837
NM_001129838
NM_001129839
NM_001129840
NM_001129841
NM_001129842
NM_001129843
NM_001129844
NM_001129846
NM_001167623
NM_001167624
NM_001167625
NM_199460
CACNA1C






















calcium channel, voltage-dependent, L type, alpha 1C subunit






















chr6_+_30852326 3.473 NM_013993
DDR1
discoidin domain receptor tyrosine kinase 1
chr8_+_21900389 3.465 NM_003867
FGF17
fibroblast growth factor 17
chr19_+_19322763 3.465 NM_004386
NCAN
neurocan
chr2_+_95963026 3.457 NM_013434
KCNIP3
Kv channel interacting protein 3, calsenilin

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
3.09 7.75e-46 GO:0007399 nervous system development
2.16 5.89e-34 GO:0048731 system development
2.01 3.94e-30 GO:0048856 anatomical structure development
1.95 5.92e-30 GO:0007275 multicellular organismal development
3.13 2.69e-27 GO:0022008 neurogenesis
1.84 1.63e-26 GO:0032502 developmental process
3.16 3.83e-26 GO:0048699 generation of neurons
1.65 1.12e-25 GO:0032501 multicellular organismal process
2.24 2.40e-25 GO:0030154 cell differentiation
2.19 3.13e-24 GO:0048869 cellular developmental process
3.33 1.14e-23 GO:0030182 neuron differentiation
2.90 2.41e-22 GO:0048468 cell development
3.46 3.68e-21 GO:0048666 neuron development
3.55 2.26e-19 GO:0000904 cell morphogenesis involved in differentiation
3.22 3.42e-18 GO:0000902 cell morphogenesis
3.45 9.22e-18 GO:0019226 transmission of nerve impulse
3.45 9.22e-18 GO:0031175 neuron projection development
3.45 9.22e-18 GO:0035637 multicellular organismal signaling
2.23 3.78e-17 GO:0009653 anatomical structure morphogenesis
3.56 6.91e-17 GO:0007268 synaptic transmission
3.06 1.03e-16 GO:0032989 cellular component morphogenesis
3.51 3.01e-16 GO:0048667 cell morphogenesis involved in neuron differentiation
2.80 3.22e-16 GO:0007267 cell-cell signaling
3.45 7.83e-16 GO:0048812 neuron projection morphogenesis
3.26 1.79e-15 GO:0048858 cell projection morphogenesis
3.23 2.93e-15 GO:0032990 cell part morphogenesis
3.48 3.47e-15 GO:0007409 axonogenesis
2.90 1.14e-14 GO:0030030 cell projection organization
2.39 1.36e-13 GO:0007154 cell communication
3.04 6.64e-13 GO:0007417 central nervous system development
1.54 2.72e-10 GO:0023052 signaling
2.38 1.63e-09 GO:0007155 cell adhesion
2.38 1.63e-09 GO:0022610 biological adhesion
3.06 4.21e-08 GO:0007411 axon guidance
2.88 2.18e-07 GO:0007420 brain development
3.15 4.15e-07 GO:0035295 tube development
2.99 4.52e-07 GO:0060284 regulation of cell development
1.68 1.68e-06 GO:0048513 organ development
2.08 1.94e-06 GO:0040011 locomotion
2.44 5.38e-06 GO:0030001 metal ion transport
2.99 5.38e-06 GO:0051960 regulation of nervous system development
1.79 6.02e-06 GO:0050877 neurological system process
1.24 6.33e-06 GO:0065007 biological regulation
1.27 9.72e-06 GO:0050794 regulation of cellular process
3.55 1.02e-05 GO:0030900 forebrain development
2.24 1.74e-05 GO:0009887 organ morphogenesis
1.66 2.41e-05 GO:0003008 system process
3.06 3.68e-05 GO:0048568 embryonic organ development
1.95 4.46e-05 GO:0006811 ion transport
1.24 7.22e-05 GO:0050789 regulation of biological process
2.91 1.20e-04 GO:0050767 regulation of neurogenesis
3.44 1.27e-04 GO:0006813 potassium ion transport
3.08 2.36e-04 GO:0045664 regulation of neuron differentiation
2.05 2.45e-04 GO:0045595 regulation of cell differentiation
2.93 2.62e-04 GO:0002009 morphogenesis of an epithelium
1.72 2.99e-04 GO:0051239 regulation of multicellular organismal process
2.12 4.57e-04 GO:0006812 cation transport
2.50 5.86e-04 GO:0044057 regulation of system process
3.73 6.69e-04 GO:0050804 regulation of synaptic transmission
3.34 7.33e-04 GO:0043062 extracellular structure organization
4.05 7.41e-04 GO:0006816 calcium ion transport
2.54 8.59e-04 GO:0007610 behavior
3.54 8.62e-04 GO:0051969 regulation of transmission of nerve impulse
2.39 9.30e-04 GO:0048598 embryonic morphogenesis
1.86 1.12e-03 GO:0009888 tissue development
2.15 1.13e-03 GO:0006935 chemotaxis
2.15 1.13e-03 GO:0042330 taxis
3.36 1.19e-03 GO:0031644 regulation of neurological system process
3.57 1.39e-03 GO:0050890 cognition
3.71 1.43e-03 GO:0007611 learning or memory
3.00 1.81e-03 GO:0035239 tube morphogenesis
1.81 2.04e-03 GO:0050793 regulation of developmental process
4.72 2.09e-03 GO:0032409 regulation of transporter activity
3.95 2.23e-03 GO:0021537 telencephalon development
3.76 2.27e-03 GO:0051924 regulation of calcium ion transport
1.37 2.35e-03 GO:0007165 signal transduction
3.69 3.07e-03 GO:0006836 neurotransmitter transport
2.48 3.10e-03 GO:0048729 tissue morphogenesis
5.75 3.73e-03 GO:0001656 metanephros development
6.97 5.52e-03 GO:0030199 collagen fibril organization
1.73 6.85e-03 GO:0032879 regulation of localization
1.85 7.04e-03 GO:2000026 regulation of multicellular organismal development
4.92 7.74e-03 GO:0032412 regulation of ion transmembrane transporter activity
1.86 8.75e-03 GO:0051049 regulation of transport
3.59 8.78e-03 GO:0021700 developmental maturation
2.33 8.88e-03 GO:0015672 monovalent inorganic cation transport
3.07 9.34e-03 GO:0060562 epithelial tube morphogenesis
2.23 9.67e-03 GO:0060429 epithelium development
1.87 1.03e-02 GO:0009790 embryo development
3.26 1.10e-02 GO:0001763 morphogenesis of a branching structure
3.52 1.16e-02 GO:0010720 positive regulation of cell development
4.73 1.19e-02 GO:0022898 regulation of transmembrane transporter activity
3.60 1.63e-02 GO:0030324 lung development
4.56 1.79e-02 GO:0007612 learning
2.95 1.80e-02 GO:0048562 embryonic organ morphogenesis
4.48 2.18e-02 GO:0021543 pallium development
4.48 2.18e-02 GO:0034765 regulation of ion transmembrane transport
5.36 2.18e-02 GO:0021987 cerebral cortex development
3.10 2.24e-02 GO:0070838 divalent metal ion transport
3.48 2.47e-02 GO:0030323 respiratory tube development
13.06 2.47e-02 GO:0005513 detection of calcium ion
5.88 2.66e-02 GO:0048489 synaptic vesicle transport
3.16 2.91e-02 GO:0010959 regulation of metal ion transport
2.27 2.95e-02 GO:0001501 skeletal system development
3.01 3.51e-02 GO:0072511 divalent inorganic cation transport
5.10 3.53e-02 GO:0014020 primary neural tube formation
4.60 3.88e-02 GO:0001764 neuron migration
3.08 4.12e-02 GO:0010769 regulation of cell morphogenesis involved in differentiation
3.20 4.22e-02 GO:0060541 respiratory system development
3.06 4.61e-02 GO:0022604 regulation of cell morphogenesis

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
3.83 2.24e-20 GO:0045202 synapse
1.88 2.19e-15 GO:0044459 plasma membrane part
3.38 7.54e-15 GO:0043005 neuron projection
1.55 3.19e-14 GO:0005886 plasma membrane
1.55 3.43e-14 GO:0071944 cell periphery
4.22 4.71e-13 GO:0034702 ion channel complex
2.73 1.05e-12 GO:0030054 cell junction
3.41 4.56e-11 GO:0044456 synapse part
4.80 6.73e-11 GO:0034703 cation channel complex
3.07 1.01e-10 GO:0031012 extracellular matrix
3.21 4.42e-10 GO:0005578 proteinaceous extracellular matrix
2.12 2.18e-08 GO:0042995 cell projection
3.68 9.64e-08 GO:0030424 axon
3.34 2.10e-06 GO:0030425 dendrite
1.79 2.37e-06 GO:0031226 intrinsic to plasma membrane
1.28 2.90e-06 GO:0044425 membrane part
1.79 3.61e-06 GO:0005887 integral to plasma membrane
1.23 5.21e-06 GO:0016020 membrane
2.41 1.53e-05 GO:0044463 cell projection part
4.33 4.18e-05 GO:0008076 voltage-gated potassium channel complex
4.33 4.18e-05 GO:0034705 potassium channel complex
4.01 6.60e-05 GO:0019717 synaptosome
4.40 1.61e-04 GO:0033267 axon part
7.21 1.73e-04 GO:0034704 calcium channel complex
3.25 1.97e-04 GO:0045211 postsynaptic membrane
1.26 3.66e-04 GO:0031224 intrinsic to membrane
7.96 1.02e-03 GO:0005891 voltage-gated calcium channel complex
5.81 1.62e-03 GO:0005581 collagen
3.33 2.26e-03 GO:0044420 extracellular matrix part
1.66 2.66e-03 GO:0044421 extracellular region part
1.80 2.70e-03 GO:0031988 membrane-bounded vesicle
4.25 2.86e-03 GO:0030426 growth cone
3.13 3.24e-03 GO:0031225 anchored to membrane
4.12 4.08e-03 GO:0030427 site of polarized growth
1.77 5.97e-03 GO:0016023 cytoplasmic membrane-bounded vesicle
1.23 6.17e-03 GO:0016021 integral to membrane
3.70 6.79e-03 GO:0014069 postsynaptic density
1.73 6.96e-03 GO:0031982 vesicle
2.71 7.16e-03 GO:0043025 neuronal cell body
16.72 8.15e-03 GO:0014701 junctional sarcoplasmic reticulum membrane
2.63 1.13e-02 GO:0044297 cell body
4.65 1.37e-02 GO:0030672 synaptic vesicle membrane
3.44 1.59e-02 GO:0030665 clathrin coated vesicle membrane
2.27 1.60e-02 GO:0030659 cytoplasmic vesicle membrane
10.45 1.67e-02 GO:0030934 anchoring collagen
1.70 1.79e-02 GO:0031410 cytoplasmic vesicle
3.36 2.07e-02 GO:0008021 synaptic vesicle
2.19 2.92e-02 GO:0012506 vesicle membrane
2.08 3.25e-02 GO:0044433 cytoplasmic vesicle part
4.18 3.55e-02 GO:0044309 neuron spine

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
3.68 6.27e-14 GO:0022836 gated channel activity
3.19 1.11e-12 GO:0022838 substrate-specific channel activity
3.14 1.21e-12 GO:0015267 channel activity
3.14 1.36e-12 GO:0022803 passive transmembrane transporter activity
3.18 2.07e-12 GO:0005216 ion channel activity
3.41 7.79e-10 GO:0005261 cation channel activity
4.12 6.68e-08 GO:0022843 voltage-gated cation channel activity
3.58 1.54e-07 GO:0005244 voltage-gated ion channel activity
3.58 1.54e-07 GO:0022832 voltage-gated channel activity
2.10 1.21e-06 GO:0015075 ion transmembrane transporter activity
3.82 1.36e-05 GO:0005267 potassium channel activity
8.21 1.37e-05 GO:0008066 glutamate receptor activity
4.70 1.52e-05 GO:0005201 extracellular matrix structural constituent
2.18 1.70e-05 GO:0008324 cation transmembrane transporter activity
1.85 1.33e-04 GO:0022891 substrate-specific transmembrane transporter activity
1.76 5.97e-04 GO:0022857 transmembrane transporter activity
1.93 6.29e-04 GO:0005509 calcium ion binding
7.24 8.96e-04 GO:0005245 voltage-gated calcium channel activity
1.71 1.11e-03 GO:0030528 transcription regulator activity
2.99 3.39e-03 GO:0005539 glycosaminoglycan binding
3.18 3.67e-03 GO:0015276 ligand-gated ion channel activity
3.18 3.67e-03 GO:0022834 ligand-gated channel activity
1.60 4.25e-03 GO:0005215 transporter activity
1.66 5.00e-03 GO:0022892 substrate-specific transporter activity
8.13 5.29e-03 GO:0005234 extracellular-glutamate-gated ion channel activity
3.80 7.19e-03 GO:0005262 calcium channel activity
3.41 7.54e-03 GO:0005249 voltage-gated potassium channel activity
2.76 1.15e-02 GO:0001871 pattern binding
2.76 1.15e-02 GO:0030247 polysaccharide binding
3.77 1.55e-02 GO:0005230 extracellular ligand-gated ion channel activity
3.98 1.78e-02 GO:0004714 transmembrane receptor protein tyrosine kinase activity
6.65 2.39e-02 GO:0016917 GABA receptor activity
1.72 4.12e-02 GO:0043565 sequence-specific DNA binding
9.50 4.21e-02 GO:0017075 syntaxin-1 binding
7.38 4.35e-02 GO:0004970 ionotropic glutamate receptor activity