Motif ID: NFE2L1.p2

Z-value: 2.717


Transcription factors associated with NFE2L1.p2:

Gene SymbolEntrez IDGene Name
NFE2L1 4779 nuclear factor (erythroid-derived 2)-like 1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
NFE2L1hg19_v1_chr17_+_46125675_461257230.701.0e-05Click!


Activity profile for motif NFE2L1.p2.

activity profile for motif NFE2L1.p2


Sorted Z-values histogram for motif NFE2L1.p2

Sorted Z-values for motif NFE2L1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NFE2L1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr2_+_88367298 8.954 NM_198274
 SMYD1
SET and MYND domain containing 1
chr5_+_36608430 6.513 NM_001166695
 SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr12_+_12938540 6.437 NM_030817
 APOLD1
apolipoprotein L domain containing 1
chr6_-_56716412 5.470 DST
dystonin
chr7_+_123249076 5.392 NM_080928
 ASB15
ankyrin repeat and SOCS box containing 15
chr12_+_81101407 4.972 NM_002469
 MYF6
myogenic factor 6 (herculin)
chr18_+_59157774 4.858 NM_031891
 CDH20
cadherin 20, type 2
chr15_+_91769329 4.825 SV2B
synaptic vesicle glycoprotein 2B
chr3_+_127641901 4.596 NM_207335
 KBTBD12
kelch repeat and BTB (POZ) domain containing 12
chr1_-_26393984 4.227 NM_032588
 TRIM63
tripartite motif containing 63
chrX_-_32430370 4.123 NM_004011
NM_004012
 DMD

dystrophin

chr17_-_42992852 4.048 NM_001131019
NM_001242376
NM_002055
 GFAP


glial fibrillary acidic protein


chr12_+_109577201 3.999 NM_001093
 ACACB
acetyl-CoA carboxylase beta
chr19_+_50706868 3.850 NM_001077186
NM_001145809
NM_024729
 MYH14


myosin, heavy chain 14, non-muscle


chr6_-_46047978 3.848 NM_001114086
 CLIC5
chloride intracellular channel 5
chr14_-_65289812 3.772 NM_000347
NM_001024858
 SPTB

spectrin, beta, erythrocytic

chr4_-_177190258 3.708 NM_080874
 ASB5
ankyrin repeat and SOCS box containing 5
chr6_+_41020939 3.659 NM_006789
 APOBEC2
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2
chr3_+_158991035 3.657 NM_001197107
NM_001197108
NM_014575
 SCHIP1


schwannomin interacting protein 1


chr2_-_142889269 3.654 NM_018557
 LRP1B
low density lipoprotein receptor-related protein 1B

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 30 entries
Enrichment   P-value GO Accession GO Term
12.87 6.66e-03 GO:0016339 calcium-dependent cell-cell adhesion
11.44 1.39e-02 GO:0031032 actomyosin structure organization
9.74 7.91e-03 GO:0006941 striated muscle contraction
6.34 4.65e-02 GO:0051147 regulation of muscle cell differentiation
5.80 3.16e-02 GO:0008016 regulation of heart contraction
5.32 4.33e-06 GO:0007517 muscle organ development
5.09 5.66e-05 GO:0003012 muscle system process
4.89 6.00e-04 GO:0006936 muscle contraction
4.38 9.76e-06 GO:0061061 muscle structure development
3.70 1.01e-02 GO:0007507 heart development
3.50 9.41e-04 GO:0044057 regulation of system process
3.16 2.46e-02 GO:0060284 regulation of cell development
2.99 1.58e-03 GO:0072358 cardiovascular system development
2.99 1.58e-03 GO:0072359 circulatory system development
2.57 1.03e-02 GO:0009887 organ morphogenesis
2.33 1.69e-08 GO:0003008 system process
2.14 7.84e-05 GO:0007399 nervous system development
2.03 9.99e-10 GO:0048731 system development
2.01 8.09e-03 GO:0051239 regulation of multicellular organismal process
2.00 1.45e-03 GO:0009653 anatomical structure morphogenesis

Gene overrepresentation in compartment category:

Showing 1 to 19 of 19 entries
Enrichment   P-value GO Accession GO Term
15.84 1.84e-02 GO:0031672 A band
14.30 3.95e-03 GO:0005859 muscle myosin complex
12.87 6.93e-03 GO:0016460 myosin II complex
10.51 6.08e-13 GO:0030017 sarcomere
10.48 5.07e-15 GO:0044449 contractile fiber part
10.21 9.40e-15 GO:0030016 myofibril
10.05 2.84e-15 GO:0043292 contractile fiber
9.66 6.45e-05 GO:0031674 I band
8.13 1.78e-02 GO:0016528 sarcoplasm
8.13 1.78e-02 GO:0030018 Z disc
6.44 6.78e-03 GO:0016459 myosin complex
3.78 4.29e-05 GO:0015629 actin cytoskeleton
3.75 1.99e-02 GO:0070161 anchoring junction
2.91 1.47e-05 GO:0030054 cell junction
2.79 5.29e-03 GO:0045202 synapse
2.01 7.93e-05 GO:0005856 cytoskeleton
1.67 3.91e-03 GO:0044459 plasma membrane part
1.53 6.03e-05 GO:0071944 cell periphery
1.53 9.62e-05 GO:0005886 plasma membrane

Gene overrepresentation in function category:

Showing 1 to 7 of 7 entries
Enrichment   P-value GO Accession GO Term
10.78 2.90e-05 GO:0008307 structural constituent of muscle
5.80 1.78e-02 GO:0005200 structural constituent of cytoskeleton
4.08 2.24e-02 GO:0005516 calmodulin binding
3.94 3.21e-06 GO:0003779 actin binding
3.10 6.81e-06 GO:0008092 cytoskeletal protein binding
2.51 2.21e-03 GO:0005198 structural molecule activity
2.22 2.67e-02 GO:0005509 calcium ion binding