Motif ID: NFIL3.p2

Z-value: 1.704


Transcription factors associated with NFIL3.p2:

Gene SymbolEntrez IDGene Name
NFIL3 4783 nuclear factor, interleukin 3 regulated

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
NFIL3hg19_v1_chr9_-_94185959_94186129-0.421.7e-02Click!


Activity profile for motif NFIL3.p2.

activity profile for motif NFIL3.p2


Sorted Z-values histogram for motif NFIL3.p2

Sorted Z-values for motif NFIL3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NFIL3.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr4_+_74269971 22.835 NM_000477
 ALB
albumin
chr10_+_135340865 20.788 NM_000773
 CYP2E1
cytochrome P450, family 2, subfamily E, polypeptide 1
chr10_-_95360959 19.989 NM_006744
 RBP4
retinol binding protein 4, plasma
chr3_+_133494275 15.858 TF
transferrin
chr10_-_82049178 12.715 NM_000429
 MAT1A
methionine adenosyltransferase I, alpha
chr3_+_186383770 11.244 NM_000412
 HRG
histidine-rich glycoprotein
chr1_+_57320442 11.132 NM_000562
 C8A
complement component 8, alpha polypeptide
chr4_+_155484131 10.480 NM_001184741
NM_005141
 FGB

fibrinogen beta chain

chr1_+_196946666 8.882 NM_030787
 CFHR5
complement factor H-related 5
chr9_-_104198045 8.699 NM_000035
 ALDOB
aldolase B, fructose-bisphosphate
chr14_-_70263871 7.861 NM_003049
 SLC10A1
solute carrier family 10 (sodium/bile acid cotransporter family), member 1
chr19_+_41497182 7.837 NM_000767
 CYP2B6
cytochrome P450, family 2, subfamily B, polypeptide 6
chr8_-_17752847 7.823 NM_147203
NM_201553
NM_004467
NM_201552
 FGL1



fibrinogen-like 1



chr19_+_41430123 7.127 CYP2B7P1
cytochrome P450, family 2, subfamily B, polypeptide 7 pseudogene 1
chr1_-_203155910 6.875 NM_001276
 CHI3L1
chitinase 3-like 1 (cartilage glycoprotein-39)
chr1_-_203155813 6.553 CHI3L1
chitinase 3-like 1 (cartilage glycoprotein-39)
chr1_-_203155745 6.520 CHI3L1
chitinase 3-like 1 (cartilage glycoprotein-39)
chr1_-_203155827 6.410 CHI3L1
chitinase 3-like 1 (cartilage glycoprotein-39)
chr19_-_41388656 6.375 NM_000764
NM_030589
 CYP2A7

cytochrome P450, family 2, subfamily A, polypeptide 7

chr6_+_131894343 6.250 NM_000045
NM_001244438
 ARG1

arginase, liver


Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 24 entries
Enrichment   P-value GO Accession GO Term
56.55 9.35e-03 GO:0042738 exogenous drug catabolic process
45.24 1.98e-02 GO:0042737 drug catabolic process
37.70 1.89e-03 GO:0015721 bile acid and bile salt transport
35.49 2.45e-03 GO:0019433 triglyceride catabolic process
34.80 4.66e-02 GO:0006957 complement activation, alternative pathway
33.51 3.14e-03 GO:0044269 glycerol ether catabolic process
33.51 3.14e-03 GO:0046461 neutral lipid catabolic process
33.51 3.14e-03 GO:0046464 acylglycerol catabolic process
27.42 7.35e-03 GO:0046503 glycerolipid catabolic process
25.14 1.06e-02 GO:0017144 drug metabolic process
12.37 3.11e-02 GO:0072376 protein activation cascade
9.08 1.71e-03 GO:0006805 xenobiotic metabolic process
9.08 1.71e-03 GO:0071466 cellular response to xenobiotic stimulus
9.01 1.81e-03 GO:0009410 response to xenobiotic stimulus
7.58 1.34e-04 GO:0008202 steroid metabolic process
5.68 6.51e-03 GO:0006954 inflammatory response
5.25 3.38e-02 GO:0010035 response to inorganic substance
3.89 2.13e-04 GO:0006952 defense response
3.71 2.07e-04 GO:0009611 response to wounding
3.34 2.08e-03 GO:0006629 lipid metabolic process

Gene overrepresentation in compartment category:

Showing 1 to 12 of 12 entries
Enrichment   P-value GO Accession GO Term
14.51 3.06e-03 GO:0031983 vesicle lumen
12.84 3.39e-02 GO:0031093 platelet alpha granule lumen
12.57 3.67e-02 GO:0034774 secretory granule lumen
12.07 4.30e-02 GO:0060205 cytoplasmic membrane-bounded vesicle lumen
7.10 5.58e-05 GO:0005792 microsome
6.86 7.79e-05 GO:0042598 vesicular fraction
3.45 1.01e-03 GO:0005615 extracellular space
3.16 5.53e-03 GO:0005624 membrane fraction
3.06 8.11e-03 GO:0005626 insoluble fraction
2.97 2.37e-03 GO:0044421 extracellular region part
2.63 1.96e-02 GO:0000267 cell fraction
2.30 1.62e-03 GO:0005576 extracellular region

Gene overrepresentation in function category:

Showing 1 to 18 of 18 entries
Enrichment   P-value GO Accession GO Term
150.79 8.47e-03 GO:0004854 xanthine dehydrogenase activity
150.79 8.47e-03 GO:0016726 oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor
150.79 8.47e-03 GO:0047042 androsterone dehydrogenase (B-specific) activity
150.79 8.47e-03 GO:0047718 indanol dehydrogenase activity
113.09 2.19e-04 GO:0047023 androsterone dehydrogenase activity
25.14 3.40e-03 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
25.14 4.18e-02 GO:0004033 aldo-keto reductase activity
23.21 4.74e-03 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
21.55 6.42e-03 GO:0016229 steroid dehydrogenase activity
16.76 2.24e-03 GO:0019825 oxygen binding
9.43 3.67e-02 GO:0004497 monooxygenase activity
7.10 3.35e-03 GO:0009055 electron carrier activity
6.65 1.75e-02 GO:0001871 pattern binding
6.65 1.75e-02 GO:0030247 polysaccharide binding
5.84 1.37e-02 GO:0005506 iron ion binding
4.55 5.90e-03 GO:0030246 carbohydrate binding
3.99 1.95e-02 GO:0008289 lipid binding
3.39 6.69e-03 GO:0016491 oxidoreductase activity