Motif ID: NFY{A,B,C}.p2

Z-value: 3.218


Transcription factors associated with NFY{A,B,C}.p2:

Gene SymbolEntrez IDGene Name
NFYA 4800 nuclear transcription factor Y, alpha
NFYB 4801 nuclear transcription factor Y, beta
NFYC 4802 nuclear transcription factor Y, gamma

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
NFYBhg19_v1_chr12_-_104531875_104532039-0.707.8e-06Click!
NFYChg19_v1_chr1_+_41157392_411573980.355.0e-02Click!
NFYAhg19_v1_chr6_+_41040687_41040712-0.336.2e-02Click!


Activity profile for motif NFY{A,B,C}.p2.

activity profile for motif NFY{A,B,C}.p2


Sorted Z-values histogram for motif NFY{A,B,C}.p2

Sorted Z-values for motif NFY{A,B,C}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NFY{A,B,C}.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr16_-_2264776 7.277 NM_001042371
 PGP
phosphoglycolate phosphatase
chr17_-_79818406 6.794 P4HB
prolyl 4-hydroxylase, beta polypeptide
chr17_-_79818444 6.689 P4HB
prolyl 4-hydroxylase, beta polypeptide
chr2_-_240322620 6.497 NM_006037
 HDAC4
histone deacetylase 4
chr19_-_2042022 6.251 MKNK2
MAP kinase interacting serine/threonine kinase 2
chr17_-_79818370 6.054 P4HB
prolyl 4-hydroxylase, beta polypeptide
chr19_-_14228362 5.978 NM_002730
 PRKACA
protein kinase, cAMP-dependent, catalytic, alpha
chr17_-_79818318 5.903 P4HB
prolyl 4-hydroxylase, beta polypeptide
chr17_-_79818418 5.845 P4HB
prolyl 4-hydroxylase, beta polypeptide
chr19_+_19174792 5.788 NM_178526
 SLC25A42
solute carrier family 25, member 42
chr9_+_131843378 5.472 NM_001135917
NM_020438
 DOLPP1

dolichyl pyrophosphate phosphatase 1

chr2_+_70142152 5.387 NM_001202513
NM_001202514
NM_002357
 MXD1


MAX dimerization protein 1


chr1_+_25757381 5.324 NM_018202
 TMEM57
transmembrane protein 57
chr19_-_14228560 5.195 PRKACA
protein kinase, cAMP-dependent, catalytic, alpha
chr14_+_24584467 5.139 NM_181357
 DCAF11
DDB1 and CUL4 associated factor 11
chr1_+_227127937 4.793 NM_020247
 ADCK3
aarF domain containing kinase 3
chr1_+_227127959 4.791 ADCK3
aarF domain containing kinase 3
chr19_+_50270068 4.723 NM_014203
NM_130787
 AP2A1

adaptor-related protein complex 2, alpha 1 subunit

chr16_-_1832576 4.720 NM_080861
 SPSB3
splA/ryanodine receptor domain and SOCS box containing 3
chr16_-_1832571 4.679 SPSB3
splA/ryanodine receptor domain and SOCS box containing 3

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 21 entries
Enrichment   P-value GO Accession GO Term
9.10 1.17e-02 GO:0006695 cholesterol biosynthetic process
8.76 3.58e-03 GO:0016126 sterol biosynthetic process
4.26 1.56e-02 GO:0006323 DNA packaging
2.52 2.12e-02 GO:0006325 chromatin organization
2.31 1.85e-02 GO:0051276 chromosome organization
1.82 6.14e-04 GO:0044281 small molecule metabolic process
1.72 9.69e-05 GO:0009058 biosynthetic process
1.68 7.99e-04 GO:0044249 cellular biosynthetic process
1.67 3.02e-02 GO:0006464 protein modification process
1.65 2.48e-02 GO:0043412 macromolecule modification
1.63 2.23e-03 GO:0044267 cellular protein metabolic process
1.62 9.05e-04 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.61 1.38e-04 GO:0034641 cellular nitrogen compound metabolic process
1.56 7.81e-04 GO:0006807 nitrogen compound metabolic process
1.50 5.98e-05 GO:0044260 cellular macromolecule metabolic process
1.49 3.39e-02 GO:0019538 protein metabolic process
1.45 1.13e-07 GO:0044238 primary metabolic process
1.45 2.57e-07 GO:0044237 cellular metabolic process
1.43 1.15e-08 GO:0008152 metabolic process
1.41 9.88e-04 GO:0043170 macromolecule metabolic process

Gene overrepresentation in compartment category:

Showing 1 to 20 of 30 entries
Enrichment   P-value GO Accession GO Term
3.38 9.68e-04 GO:0005792 microsome
3.27 1.58e-03 GO:0042598 vesicular fraction
2.90 3.54e-02 GO:0000785 chromatin
2.83 2.92e-02 GO:0005759 mitochondrial matrix
2.83 4.53e-02 GO:0005635 nuclear envelope
2.46 9.59e-04 GO:0005694 chromosome
2.37 1.56e-02 GO:0044427 chromosomal part
2.31 5.18e-04 GO:0031967 organelle envelope
2.27 7.83e-04 GO:0031975 envelope
2.23 2.89e-03 GO:0044429 mitochondrial part
1.88 8.68e-04 GO:0005739 mitochondrion
1.80 3.22e-06 GO:0070013 intracellular organelle lumen
1.79 4.02e-06 GO:0043233 organelle lumen
1.78 4.26e-06 GO:0031974 membrane-enclosed lumen
1.73 8.60e-05 GO:0044428 nuclear part
1.73 2.15e-02 GO:0005654 nucleoplasm
1.67 3.89e-03 GO:0031981 nuclear lumen
1.60 6.64e-03 GO:0005829 cytosol
1.59 3.62e-12 GO:0005634 nucleus
1.54 2.41e-02 GO:0031090 organelle membrane

Gene overrepresentation in function category:

Showing 1 to 6 of 6 entries
Enrichment   P-value GO Accession GO Term
5.27 5.87e-03 GO:0031625 ubiquitin protein ligase binding
2.12 6.05e-03 GO:0019899 enzyme binding
1.40 4.36e-02 GO:0003676 nucleic acid binding
1.32 8.84e-03 GO:0003824 catalytic activity
1.27 2.24e-03 GO:0005515 protein binding
1.17 7.25e-05 GO:0005488 binding