Motif ID: NKX3-1.p2

Z-value: 1.496


Transcription factors associated with NKX3-1.p2:

Gene SymbolEntrez IDGene Name
NKX3-1 4824 NK3 homeobox 1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
NKX3-1hg19_v1_chr8_-_23540401_23540462-0.009.9e-01Click!


Activity profile for motif NKX3-1.p2.

activity profile for motif NKX3-1.p2


Sorted Z-values histogram for motif NKX3-1.p2

Sorted Z-values for motif NKX3-1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NKX3-1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr9_-_104198045 7.424 NM_000035
ALDOB
aldolase B, fructose-bisphosphate
chr4_+_88896838 5.967 SPP1
secreted phosphoprotein 1
chr4_+_88896801 5.608 NM_000582
NM_001040058
NM_001040060
NM_001251829
NM_001251830
SPP1




secreted phosphoprotein 1




chr4_+_88896868 5.508 SPP1
secreted phosphoprotein 1
chr4_+_88896899 5.039 SPP1
secreted phosphoprotein 1
chr6_+_131958441 4.936 NM_005021
ENPP3
ectonucleotide pyrophosphatase/phosphodiesterase 3
chr12_+_41831484 4.509 NM_013377
PDZRN4
PDZ domain containing ring finger 4
chr17_-_64225496 4.304 NM_000042
APOH
apolipoprotein H (beta-2-glycoprotein I)
chrX_-_131261871 3.951 NM_194277
FRMD7
FERM domain containing 7
chr10_+_101088794 3.844 NM_020348
CNNM1
cyclin M1
chr4_+_74269971 3.426 NM_000477
ALB
albumin
chr17_-_56492938 3.382 RNF43
ring finger protein 43
chr5_+_156696351 3.293 NM_014376
CYFIP2
cytoplasmic FMR1 interacting protein 2
chr3_-_42917191 3.069 CYP8B1
cytochrome P450, family 8, subfamily B, polypeptide 1
chr2_+_135596185 2.800 NM_138326
ACMSD
aminocarboxymuconate semialdehyde decarboxylase
chr8_-_124749573 2.739 NM_001003954
NM_004306
ANXA13

annexin A13

chr5_+_92918924 2.700 NM_005654
NR2F1
nuclear receptor subfamily 2, group F, member 1
chr15_+_59904090 2.699 GCNT3
glucosaminyl (N-acetyl) transferase 3, mucin type
chr2_+_102953716 2.674 NM_003856
IL1RL1
interleukin 1 receptor-like 1
chr12_-_103311380 2.632 NM_000277
PAH
phenylalanine hydroxylase

Gene Ontology Analysis

Nothing significant found in process category.

Gene overrepresentation in compartment category:

Showing 1 to 9 of 9 entries
Enrichment   P-value GO Accession GO Term
65.80 8.35e-04 GO:0005577 fibrinogen complex
13.07 2.21e-02 GO:0031093 platelet alpha granule lumen
12.80 2.40e-02 GO:0034774 secretory granule lumen
12.29 2.81e-02 GO:0060205 cytoplasmic membrane-bounded vesicle lumen
11.82 3.27e-02 GO:0031983 vesicle lumen
10.78 4.66e-02 GO:0031091 platelet alpha granule
3.34 8.47e-05 GO:0044421 extracellular region part
3.10 8.51e-03 GO:0005615 extracellular space
2.83 5.38e-07 GO:0005576 extracellular region

Gene overrepresentation in function category:

Showing 1 to 3 of 3 entries
Enrichment   P-value GO Accession GO Term
13.66 3.28e-02 GO:0019825 oxygen binding
9.60 2.76e-02 GO:0004497 monooxygenase activity
9.60 2.76e-02 GO:0005201 extracellular matrix structural constituent