Motif ID: NR1H4.p2

Z-value: 1.165


Transcription factors associated with NR1H4.p2:

Gene SymbolEntrez IDGene Name
NR1H4 9971 nuclear receptor subfamily 1, group H, member 4

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
NR1H4hg19_v1_chr12_+_100867739_100867751-0.125.1e-01Click!


Activity profile for motif NR1H4.p2.

activity profile for motif NR1H4.p2


Sorted Z-values histogram for motif NR1H4.p2

Sorted Z-values for motif NR1H4.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NR1H4.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_+_32739711 2.967 NM_001042771
LCK
lymphocyte-specific protein tyrosine kinase
chr9_-_137809710 2.928 NM_002003
FCN1
ficolin (collagen/fibrinogen domain containing) 1
chr14_-_106237675 2.640 IGHM
immunoglobulin heavy constant mu
chr3_+_111261039 2.640 CD96
CD96 molecule
chr14_-_106092256 2.603 IGHG4
immunoglobulin heavy constant gamma 4 (G4m marker)
chr3_+_111260925 2.561 NM_005816
NM_198196
CD96

CD96 molecule

chr14_-_106111114 2.513 IGHG2
immunoglobulin heavy constant gamma 2 (G2m marker)
chr5_+_133450353 2.393 NM_003202
TCF7
transcription factor 7 (T-cell specific, HMG-box)
chr14_-_25103365 2.331 NM_004131
GZMB
granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
chr19_+_7741934 2.237 NM_174918
C19orf59
chromosome 19 open reading frame 59
chr4_-_71532341 2.105 NM_144646
IGJ
immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
chr1_+_32716839 2.061 NM_005356
LCK
lymphocyte-specific protein tyrosine kinase
chr12_+_69742140 2.010 LYZ
lysozyme
chr3_+_122296432 2.008 NM_001113523
PARP15
poly (ADP-ribose) polymerase family, member 15
chr20_+_30639981 1.875 NM_001172129
NM_001172130
NM_001172131
NM_001172132
NM_001172133
NM_002110
HCK





hemopoietic cell kinase





chr11_-_64511550 1.790 NM_001098671
RASGRP2
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr19_-_51875790 1.781 NM_005601
NKG7
natural killer cell group 7 sequence
chr19_-_11689765 1.779 NM_001111035
NM_001111036
ACP5

acid phosphatase 5, tartrate resistant

chr19_+_1026271 1.765 NM_004368
NM_201277
CNN2

calponin 2

chr11_+_117857123 1.764 IL10RA
interleukin 10 receptor, alpha

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 12 of 12 entries
Enrichment   P-value GO Accession GO Term
122.38 4.65e-02 GO:0050765 negative regulation of phagocytosis
21.30 1.71e-02 GO:0032680 regulation of tumor necrosis factor production
19.21 2.57e-02 GO:0006909 phagocytosis
10.00 1.38e-02 GO:0002697 regulation of immune effector process
8.36 3.77e-02 GO:0002696 positive regulation of leukocyte activation
8.22 4.14e-02 GO:0050867 positive regulation of cell activation
7.53 1.81e-02 GO:0002694 regulation of leukocyte activation
7.24 2.31e-02 GO:0050865 regulation of cell activation
5.76 4.52e-06 GO:0006955 immune response
4.41 4.35e-06 GO:0002376 immune system process
4.28 2.05e-02 GO:0002682 regulation of immune system process
1.81 2.25e-03 GO:0050896 response to stimulus

Gene overrepresentation in compartment category:

Showing 1 to 1 of 1 entries
Enrichment   P-value GO Accession GO Term
2.32 3.58e-02 GO:0005576 extracellular region

Gene overrepresentation in function category:

Showing 1 to 1 of 1 entries
Enrichment   P-value GO Accession GO Term
61.20 4.36e-14 GO:0003823 antigen binding