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Motif ID: NR1H4.p2

Z-value: 1.165

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr1_+_32739711	2.967	NM_001042771	LCK	lymphocyte-specific protein tyrosine kinase
chr9_-_137809710	2.928	NM_002003	FCN1	ficolin (collagen/fibrinogen domain containing) 1
chr14_-_106237675	2.640		IGHM	immunoglobulin heavy constant mu
chr3_+_111261039	2.640		CD96	CD96 molecule
chr14_-_106092256	2.603		IGHG4	immunoglobulin heavy constant gamma 4 (G4m marker)
chr3_+_111260925	2.561	NM_005816 NM_198196	CD96	CD96 molecule
chr14_-_106111114	2.513		IGHG2	immunoglobulin heavy constant gamma 2 (G2m marker)
chr5_+_133450353	2.393	NM_003202	TCF7	transcription factor 7 (T-cell specific, HMG-box)
chr14_-_25103365	2.331	NM_004131	GZMB	granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
chr19_+_7741934	2.237	NM_174918	C19orf59	chromosome 19 open reading frame 59
chr4_-_71532341	2.105	NM_144646	IGJ	immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
chr1_+_32716839	2.061	NM_005356	LCK	lymphocyte-specific protein tyrosine kinase
chr12_+_69742140	2.010		LYZ	lysozyme
chr3_+_122296432	2.008	NM_001113523	PARP15	poly (ADP-ribose) polymerase family, member 15
chr20_+_30639981	1.875	NM_001172129 NM_001172130 NM_001172131 NM_001172132 NM_001172133 NM_002110	HCK	hemopoietic cell kinase
chr11_-_64511550	1.790	NM_001098671	RASGRP2	RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr19_-_51875790	1.781	NM_005601	NKG7	natural killer cell group 7 sequence
chr19_-_11689765	1.779	NM_001111035 NM_001111036	ACP5	acid phosphatase 5, tartrate resistant
chr19_+_1026271	1.765	NM_004368 NM_201277	CNN2	calponin 2
chr11_+_117857123	1.764		IL10RA	interleukin 10 receptor, alpha
chr5_-_176326314	1.754	NM_002115	HK3	hexokinase 3 (white cell)
chr6_-_49681245	1.746	NM_001142407 NM_001142408 NM_001142417 NM_001142435 NM_003296	CRISP2	cysteine-rich secretory protein 2
chr6_-_32160289	1.686		GPSM3	G-protein signaling modulator 3
chr2_+_192542860	1.670	NM_001031716	OBFC2A	oligonucleotide/oligosaccharide-binding fold containing 2A
chr1_-_25256767	1.664	NM_004350	RUNX3	runt-related transcription factor 3
chr3_+_186560462	1.657	NM_001177800 NM_004797	ADIPOQ	adiponectin, C1Q and collagen domain containing
chr17_-_43319100	1.657
chr19_+_1026608	1.655		CNN2	calponin 2
chr4_-_71532206	1.635		IGJ	immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
chr3_+_186560478	1.613		ADIPOQ	adiponectin, C1Q and collagen domain containing
chr22_+_45072936	1.608		PRR5	proline rich 5 (renal)
chr19_+_1026627	1.589		CNN2	calponin 2
chr20_+_43803539	1.586	NM_002638	PI3	peptidase inhibitor 3, skin-derived
chr8_+_11351509	1.578	NM_001715	BLK	B lymphoid tyrosine kinase
chr11_-_5275904	1.535	NM_000184	HBG1 HBG2	hemoglobin, gamma A hemoglobin, gamma G
chr22_-_23922376	1.511	NM_020070 NM_152855	IGLL1	immunoglobulin lambda-like polypeptide 1
chr14_-_106552313	1.492		IGHA1 IGHD IGHG1	immunoglobulin heavy constant alpha 1 immunoglobulin heavy constant delta immunoglobulin heavy constant gamma 1 (G1m marker)
chr19_+_1026582	1.488		CNN2	calponin 2
chr3_-_50383009	1.434	NM_015896	ZMYND10	zinc finger, MYND-type containing 10
chr19_+_1026624	1.422		CNN2	calponin 2
chr19_+_859658	1.419	NM_001928	CFD	complement factor D (adipsin)
chrX_+_128913881	1.388	NM_018990	SASH3	SAM and SH3 domain containing 3
chr16_+_30194925	1.383		CORO1A	coronin, actin binding protein, 1A
chr17_-_27038871	1.372	NM_152465	PROCA1	protein interacting with cyclin A1
chr1_+_12123433	1.367	NM_001243	TNFRSF8	tumor necrosis factor receptor superfamily, member 8
chr14_-_107099379	1.351		IGHG1 IGHG3	immunoglobulin heavy constant gamma 1 (G1m marker) immunoglobulin heavy constant gamma 3 (G3m marker)
chr19_+_859673	1.342		CFD	complement factor D (adipsin)
chr19_-_11689591	1.334	NM_001111034	ACP5	acid phosphatase 5, tartrate resistant
chr16_+_30194730	1.330	NM_001193333 NM_007074	CORO1A	coronin, actin binding protein, 1A
chr22_+_22569155	1.318
chr14_-_106994001	1.318		IGHV3-48 IGH@ IGHA1 IGHM	immunoglobulin heavy variable 3-48 immunoglobulin heavy locus immunoglobulin heavy constant alpha 1 immunoglobulin heavy constant mu
chrX_-_70838298	1.298	NM_001142797 NM_001504	CXCR3	chemokine (C-X-C motif) receptor 3
chr6_+_31554975	1.290	NM_001166538 NM_007161 NM_205840	LST1	leukocyte specific transcript 1
chr22_-_21386837	1.274	NM_004173	SLC7A4	solute carrier family 7 (orphan transporter), member 4
chr11_+_128563772	1.273	NM_001167681 NM_002017	FLI1	Friend leukemia virus integration 1
chr17_+_59529778	1.268		TBX4	T-box 4
chr22_+_23134980	1.259
chr17_-_73840495	1.240		UNC13D	unc-13 homolog D (C. elegans)
chrX_+_65235279	1.227
chr22_+_45072687	1.214	NM_001017530 NM_001198721 NM_015366	PRR5	proline rich 5 (renal)
chrX_+_1387692	1.211	NM_001161529 NM_001161531 NM_001161532 NM_006140 NM_172245 NM_172246 NM_172249	CSF2RA	colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)
chr5_-_171615239	1.211		STK10	serine/threonine kinase 10
chr18_-_46469118	1.201	NM_001190823	SMAD7	SMAD family member 7
chr11_-_118123001	1.192	NM_198275	MPZL3	myelin protein zero-like 3
chr9_-_37034358	1.180	NM_016734	PAX5	paired box 5
chr12_-_7281374	1.175	NM_031491	RBP5	retinol binding protein 5, cellular
chr14_-_91710851	1.172	NM_001177676	GPR68	G protein-coupled receptor 68
chrX_-_49965003	1.171	NM_139289	AKAP4	A kinase (PRKA) anchor protein 4
chr11_-_6676851	1.162	NM_003737	DCHS1	dachsous 1 (Drosophila)
chr6_-_133084585	1.160	NM_078488	VNN2	vanin 2
chr17_-_73840422	1.154		UNC13D	unc-13 homolog D (C. elegans)
chr11_+_119076974	1.148	NM_005188	CBL	Cas-Br-M (murine) ecotropic retroviral transforming sequence
chr8_-_57359148	1.135	NM_001135690	PENK	proenkephalin
chr22_+_22712091	1.134		IGLV1-44 IGL@	immunoglobulin lambda variable 1-44 immunoglobulin lambda locus
chr19_+_36203829	1.127	NM_014383	ZBTB32	zinc finger and BTB domain containing 32
chr19_-_42947050	1.124	NM_198477	CXCL17	chemokine (C-X-C motif) ligand 17
chr7_+_2671582	1.123	NM_025250	TTYH3	tweety homolog 3 (Drosophila)
chr11_-_62380202	1.121	NM_153265	EML3	echinoderm microtubule associated protein like 3
chrX_+_107288199	1.116	NM_001170553 NM_182607	VSIG1	V-set and immunoglobulin domain containing 1
chr18_-_67624159	1.115	NM_006566	CD226	CD226 molecule
chr19_-_47290541	1.105	NM_001145144	SLC1A5	solute carrier family 1 (neutral amino acid transporter), member 5
chr1_+_29241002	1.103	NM_001166006	EPB41	erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked)
chr4_-_40631846	1.095	NM_001098634	RBM47	RNA binding motif protein 47
chr7_+_2671630	1.083		TTYH3	tweety homolog 3 (Drosophila)
chr3_-_58652469	1.072	NM_138805	FAM3D	family with sequence similarity 3, member D
chrX_+_106449861	1.056	NM_001169154 NM_173494	CXorf41	chromosome X open reading frame 41
chr1_+_32757702	1.046		HDAC1	histone deacetylase 1
chr1_+_32757707	1.037	NM_004964	HDAC1	histone deacetylase 1
chr12_+_6898605	1.036	NM_000616 NM_001195014 NM_001195015 NM_001195016 NM_001195017	CD4	CD4 molecule
chr12_+_6898673	1.034		CD4	CD4 molecule
chr12_+_6898699	1.021		CD4	CD4 molecule
chr11_-_64510339	1.006		RASGRP2	RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr17_-_73840587	1.003	NM_199242	UNC13D	unc-13 homolog D (C. elegans)
chrX_-_118827322	0.992	NM_015129 NM_145799 NM_145800 NM_145802	SEPT6	septin 6
chr17_-_56409868	0.992
chr1_+_171217632	0.982	NM_002021	FMO1	flavin containing monooxygenase 1
chr19_-_39826625	0.979		GMFG	glia maturation factor, gamma
chr1_+_178482211	0.968	NM_001170722 NM_001170723 NM_001170724 NM_032126	C1orf49	chromosome 1 open reading frame 49
chr4_+_36283243	0.967	NM_001136536	DTHD1	death domain containing 1
chr19_-_51530781	0.966	NM_144947	KLK11	kallikrein-related peptidase 11
chr1_+_32757711	0.959		HDAC1	histone deacetylase 1
chr16_+_81478774	0.956	NM_198390	CMIP	c-Maf inducing protein
chr12_-_57873364	0.950	NM_001080157	ARHGAP9	Rho GTPase activating protein 9
chrY_+_1337692	0.950	NM_001161529 NM_001161531 NM_001161532 NM_006140 NM_172245 NM_172246 NM_172249	CSF2RA	colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)
chr5_-_33891967	0.940	NM_030955	ADAMTS12	ADAM metallopeptidase with thrombospondin type 1 motif, 12
chr19_-_18385166	0.939	NM_001145304 NM_001145305 NM_025249	KIAA1683	KIAA1683
chr11_+_119077021	0.936		CBL	Cas-Br-M (murine) ecotropic retroviral transforming sequence
chr16_+_57702156	0.922	NM_170776	GPR97	G protein-coupled receptor 97
chr13_+_31506809	0.919	NM_152325	C13orf26	chromosome 13 open reading frame 26
chr19_-_8567473	0.915	NM_032152	PRAM1	PML-RARA regulated adaptor molecule 1
chr14_-_69444970	0.914		ACTN1	actinin, alpha 1
chr1_+_29213569	0.905	NM_001166005 NM_001166007 NM_004437 NM_203342 NM_203343	EPB41	erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked)
chr12_+_69742130	0.901	NM_000239	LYZ	lysozyme
chr1_-_47695442	0.897	NM_003189	TAL1	T-cell acute lymphocytic leukemia 1
chr11_+_67806454	0.895	NM_006019	TCIRG1	T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3
chr1_-_25256718	0.891		RUNX3	runt-related transcription factor 3
chr5_-_171615199	0.879		STK10	serine/threonine kinase 10
chr1_+_154293568	0.877	NM_080429	AQP10	aquaporin 10
chr12_+_6898705	0.876		CD4	CD4 molecule
chr10_-_71906452	0.876	NM_001040273 NM_173555	TYSND1	trypsin domain containing 1
chr21_-_46707748	0.873	NM_015227 NM_133635	POFUT2	protein O-fucosyltransferase 2
chr19_-_51893791	0.866	NM_001193623	LOC147646	uncharacterized LOC147646
chr11_-_58345593	0.866	NM_001143995	LPXN	leupaxin
chr19_+_52264452	0.865	NM_001005738	FPR2	formyl peptide receptor 2
chr6_+_152011630	0.864	NM_001122742	ESR1	estrogen receptor 1
chr9_-_117444368	0.861	NM_001199233	LOC100505478	uncharacterized LOC100505478
chr20_+_57594308	0.855	NM_030773	TUBB1	tubulin, beta 1 class VI
chr1_-_149908098	0.850	NM_181873	MTMR11	myotubularin related protein 11
chr3_-_151102536	0.840	NM_022788	P2RY12	purinergic receptor P2Y, G-protein coupled, 12
chr1_+_160765927	0.828	NM_001033667 NM_002348	LY9	lymphocyte antigen 9
chr17_-_62207475	0.825	NM_001433	ERN1	endoplasmic reticulum to nucleus signaling 1
chr11_-_5271035	0.825	NM_000559	HBG1	hemoglobin, gamma A
chr5_-_66492574	0.817	NM_005582	CD180	CD180 molecule
chr17_+_7533403	0.814		SHBG	sex hormone-binding globulin
chr2_-_182545212	0.812	NM_002500	CERKL NEUROD1	ceramide kinase-like neurogenic differentiation 1
chr4_-_76944585	0.809	NM_001565	CXCL10	chemokine (C-X-C motif) ligand 10
chr3_-_15374082	0.795	NM_004844	SH3BP5	SH3-domain binding protein 5 (BTK-associated)
chr16_-_87525317	0.790	NM_015144	ZCCHC14	zinc finger, CCHC domain containing 14
chr4_+_100737980	0.788	NM_014395	DAPP1	dual adaptor of phosphotyrosine and 3-phosphoinositides
chrX_-_118827116	0.783		SEPT6	septin 6
chr1_-_16539103	0.783	NM_153213	ARHGEF19	Rho guanine nucleotide exchange factor (GEF) 19
chr3_-_182880463	0.780	NM_014398	LAMP3	lysosomal-associated membrane protein 3
chr17_+_7812703	0.770		CHD3	chromodomain helicase DNA binding protein 3
chr17_-_26879577	0.765		UNC119	unc-119 homolog (C. elegans)
chr15_+_81517639	0.764	NM_172217	IL16	interleukin 16
chr12_+_60083125	0.764	NM_004731	SLC16A7	solute carrier family 16, member 7 (monocarboxylic acid transporter 2)
chr2_-_85637486	0.761	NM_001747	CAPG	capping protein (actin filament), gelsolin-like
chr17_-_26879645	0.756	NM_005148 NM_054035	UNC119	unc-119 homolog (C. elegans)
chr3_+_52828783	0.748	NM_002217	ITIH3	inter-alpha-trypsin inhibitor heavy chain 3
chr14_-_106518424	0.737		IGH@ IGHA1 IGHG1 IGHG2 IGHM	immunoglobulin heavy locus immunoglobulin heavy constant alpha 1 immunoglobulin heavy constant gamma 1 (G1m marker) immunoglobulin heavy constant gamma 2 (G2m marker) immunoglobulin heavy constant mu
chr2_+_177016112	0.735	NM_014621	HOXD4	homeobox D4
chr10_+_26727282	0.729		APBB1IP	amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
chr1_+_26872306	0.725		RPS6KA1	ribosomal protein S6 kinase, 90kDa, polypeptide 1
chr15_+_39873276	0.724	NM_003246	THBS1	thrombospondin 1
chr1_+_154300275	0.724	NM_020452	ATP8B2	ATPase, class I, type 8B, member 2
chr17_-_62207362	0.719		ERN1	endoplasmic reticulum to nucleus signaling 1
chr7_+_100199881	0.713	NM_002593	PCOLCE	procollagen C-endopeptidase enhancer
chr17_-_59940669	0.713	NM_032043	BRIP1	BRCA1 interacting protein C-terminal helicase 1
chr17_-_61920029	0.709		SMARCD2	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2
chr1_-_36789754	0.707	NM_018166	FAM176B	family with sequence similarity 176, member B
chr19_+_10197023	0.707		C19orf66	chromosome 19 open reading frame 66
chr17_-_47841517	0.706	NM_030802	FAM117A	family with sequence similarity 117, member A
chr1_+_25598883	0.704	NM_001127691 NM_016124	RHD	Rh blood group, D antigen
chr11_-_119076888	0.704		CCDC153	coiled-coil domain containing 153
chr14_-_106471439	0.696		IGHA1 IGHG1 IGHM	immunoglobulin heavy constant alpha 1 immunoglobulin heavy constant gamma 1 (G1m marker) immunoglobulin heavy constant mu
chr3_+_46448678	0.696	NM_003965 NM_001130910	CCRL2	chemokine (C-C motif) receptor-like 2
chrX_-_133119624	0.694	NM_001164617 NM_001164618 NM_001164619 NM_004484	GPC3	glypican 3
chr2_+_98330030	0.693	NM_001079	ZAP70	zeta-chain (TCR) associated protein kinase 70kDa
chr11_-_6341708	0.689	NM_145040	PRKCDBP	protein kinase C, delta binding protein
chr16_+_23847359	0.675		PRKCB	protein kinase C, beta
chr17_-_76899282	0.673	NM_001243540 NM_001243541	LOC100653515	differential display clone 8
chr3_-_15373807	0.665		SH3BP5	SH3-domain binding protein 5 (BTK-associated)
chr12_-_122107559	0.665	NM_173855	MORN3	MORN repeat containing 3
chr9_+_117373622	0.662	NM_153045	C9orf91	chromosome 9 open reading frame 91
chr9_-_34691135	0.659	NM_006274	CCL19	chemokine (C-C motif) ligand 19
chr19_+_54372659	0.652	NM_001020821 NM_001020818	MYADM	myeloid-associated differentiation marker
chr19_+_35607218	0.652		FXYD3	FXYD domain containing ion transport regulator 3
chr11_-_123756339	0.651	NM_001013743	TMEM225	transmembrane protein 225
chr13_-_46961314	0.648		KIAA0226L	KIAA0226-like
chr1_+_199996729	0.648	NM_003822 NM_205860	NR5A2	nuclear receptor subfamily 5, group A, member 2
chr12_-_89745753	0.645		DUSP6	dual specificity phosphatase 6
chr7_-_21985421	0.638	NM_001127370 NM_001127371 NM_018719	CDCA7L	cell division cycle associated 7-like
chrX_-_47489243	0.636	NM_001145252	CFP	complement factor properdin
chrX_-_118827060	0.636		SEPT6	septin 6
chr22_+_38035718	0.632		SH3BP1	SH3-domain binding protein 1
chr12_-_6756533	0.627	NM_032489	ACRBP	acrosin binding protein
chr17_-_8301143	0.627	NM_001146684	RNF222	ring finger protein 222
chr1_+_151483861	0.626	NM_020770	CGN	cingulin
chr19_+_10196972	0.623		C19orf66	chromosome 19 open reading frame 66
chr15_+_40453263	0.623		BUB1B	budding uninhibited by benzimidazoles 1 homolog beta (yeast)
chr2_+_27371858	0.621	NM_175769	TCF23	transcription factor 23
chr1_+_21766559	0.621	NM_032264	NBPF3	neuroblastoma breakpoint family, member 3
chr19_+_51226593	0.617	NM_002975	CLEC11A	C-type lectin domain family 11, member A
chr2_+_219433302	0.614		RQCD1	RCD1 required for cell differentiation1 homolog (S. pombe)
chr19_-_17516383	0.610	NM_004335	BST2	bone marrow stromal cell antigen 2
chr19_+_36505409	0.610
chr6_+_29974352	0.610		HLA-J	major histocompatibility complex, class I, J (pseudogene)
chr6_-_24719286	0.609	NM_030939	C6orf62	chromosome 6 open reading frame 62
chr1_-_211848820	0.607	NM_001204182 NM_001204183 NM_002497	NEK2	NIMA (never in mitosis gene a)-related kinase 2
chr1_-_150693321	0.605	NM_001199829 NM_032132	HORMAD1	HORMA domain containing 1

Gene overrepresentation in process category:

Enrichment	P-value	GO Accession	GO Term
4.41	4.35e-06	GO:0002376	immune system process
5.76	4.52e-06	GO:0006955	immune response
1.81	2.25e-03	GO:0050896	response to stimulus
10.00	1.38e-02	GO:0002697	regulation of immune effector process
21.30	1.71e-02	GO:0032680	regulation of tumor necrosis factor production
7.53	1.81e-02	GO:0002694	regulation of leukocyte activation
4.28	2.05e-02	GO:0002682	regulation of immune system process
7.24	2.31e-02	GO:0050865	regulation of cell activation
19.21	2.57e-02	GO:0006909	phagocytosis
8.36	3.77e-02	GO:0002696	positive regulation of leukocyte activation
8.22	4.14e-02	GO:0050867	positive regulation of cell activation
122.38	4.65e-02	GO:0050765	negative regulation of phagocytosis

Gene overrepresentation in compartment category:

Enrichment	P-value	GO Accession	GO Term
2.32	3.58e-02	GO:0005576	extracellular region

Gene overrepresentation in function category:

Enrichment	P-value	GO Accession	GO Term
61.20	4.36e-14	GO:0003823	antigen binding